{"title":"Evaluation of the Modified SAMe-TT2R2 Score to Predict Good Anticoagulation Control with Warfarin Among non-valvular Atrial Fibrillation Patients","authors":"R. Bahmaid, Filwah Almarzouq","doi":"10.47363/jcrrr/2021(2)155","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(2)155","url":null,"abstract":"Background: The SAMe-TT2 R2 Score was developed to identify vitamin K antagonists control outliers before non-valvular atrial fibrillation (AF) patients start treatment. SAMe-TT2 R2 Score was derived and validated using a primarily white Caucasian population to predict TTR. Given that non-Caucasian race already confers 2 points in this score, the SAMe-TT2 R2 score requires validation and/or re-calibration despite race of population. Method: We conducted a cohort retrospective study that included all non-valvular atrial fibrillation patients who were on warfarin therapy from January to December 2019. Then we calculated the modified SAMe-TT2 R2 and SAMe-TT2 R2 for all study populations and we correlated the result with patients' TTR. The TTR was calculated through the Rosendaal's method. Results: We had 662 patient using warfarin therapy, among those 662, 60.9% were under cardiology and using it for cardiac indication, and only 18.1% diagnosed to have non-valvular AF. Modified SAMe-TT2 R2 score has good relation to original SAMe-TT2 R2 score as showed 75.71% (95% CI. 63.99 to 85.17%), 100% (95% CI. 92.89 to 100%) and 15% (95% CI. 3.21 to 77.95%); accuracy, sensitivity and specificity in relation to SAMe-TT2 R2 respectively. In addition to that in this small cohort we found that there is universal relationship between SAMe-TT2 R2 score, Modified SAMe-TT2 R2 score and TTR; TTR >=65% associate with low score (<2) of both SAMe-TT2 R2 , Modified SAMe-TT2 R2 score. Conclusion: The use of Modified SAMe-TT2 R2 score allows clinicians to make an informed decision on whether to start vitamin K antagonist or other non-vitamin K antagonist oral anticoagulant despite the race of the patients.","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115046633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Chronic Kidney Disease on Outcomes in Patients Admitted to the Hospital for Paroxysmal Atrial Fibrillation: A National Inpatient Sample Database Analysis","authors":"A. Gulati","doi":"10.47363/jcrrr/2021(2)153","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(2)153","url":null,"abstract":"","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128798376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unusual Case of a Massive Cardiomegaly","authors":"A. Mendes","doi":"10.47363/jcrrr/2021(2)151","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(2)151","url":null,"abstract":"We report a case of a 74-year-old woman that was admitted in the emergency department complaining of severe leg edema, progressive and persistent dyspnea at rest, easy fatiguability and paroxysmal nocturnal dyspnea aggravated over the past 4 months. According to her personal and medical history, she had been not attending to her medical appointments and, therefore, missed the close heart failure (HF) monitoring that was demanded.","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121337398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Fogante, Azienda Ospedaliero-Universitaria “Ospedali Riuniti” Ancona
{"title":"Relationship between Epicardial Adipose Tissue and High-Risk Coronary Plaque Features in Patients with Suspected Acute Coronary Syndrome","authors":"M. Fogante, Azienda Ospedaliero-Universitaria “Ospedali Riuniti” Ancona","doi":"10.47363/jcrrr/2021(2)148","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(2)148","url":null,"abstract":"Objective: To evaluate the association between EAT volume and attenuation and high-risk coronary plaque (HRP) in patients with suspected acute coronary syndrome (ACS). Material and Methods: In this prospective study were enrolled, from November 2020 to August 2021, consecutive patients who underwent cardiac computed tomography (CCT) for suspected ACS. All exams were performed using a 2x192-slice dual source CT scanner. EAT volume and attenuation were evaluated in all patients. HRP was defined as plaque with more than 2 high-risk features (low attenuation plaque, positive remolding, napkin-ring sign, spotty calcification) on CCT image. Based on the presence or absence of HRP patients were divided into two groups and EAT volume and attenuation were compared. Results: In this study were enrolled 106 patients: 37 with HRP and 69 without HRP. Patients with HRP have higher EAT volume and attenuation than those without HRP, respectively, 119.0±14.0 cm3 vs 96.3±8.3 cm3 (p<0.0001) and -85.7±15.7 HU vs -95.0±18.4 HU (p=0.0108). After adjustment by coronary calcium score (CCS) and coronary stenosis, EAT volume and attenuation were independent risk predictors of presence of HRP. Conclusions: Higher EAT volume and attenuation are associated with HRP in patient with ACS and are independent of CCS and coronary stenosis.","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121721149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Covid-19 Effects on the Cardiovascular System; A Focus on Myocarditis","authors":"Praise E Chovwen, Ibukun Oshobu","doi":"10.47363/jcrrr/2021(2)147","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(2)147","url":null,"abstract":"The WHO declared COVID 19 a global pandemic on March 11, 2020. The effect the virus has created in various aspects of our lives has made it of primary importance that we understand its pathophysiology, complication, preventive care, and treatment. A significant number of COVID patients develop some form of cardiac injury, whether while infected or after recovery. In this article, we aim to discuss these aspects and expand further on the cardiovascular effects seen in COVID 19 infected patients, emphasizing myocarditis. We discuss the case of a patient who developed cardiac injuries while infected with COVID 19, which she contacted 18 days after receiving the first dose of the COVID mRNA vaccine. This article provides more understanding of the relationship between COVID-19 and the heart.","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128598093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selected Landmark Studies in the Role of the Mesolimbic System","authors":"Prakul Suresh, B. Baccouche","doi":"10.47363/jcrrr/2021(3)144","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(3)144","url":null,"abstract":"The mesolimbic system has been demonstrated to have a major role in the perception of pain, but the mechanisms by which this occurs are poorly understood. In this paper, we review selected landmark studies that have contributed to our present understanding of the role of the mesolimbic system. The included studies outline the molecular mechanisms of the mesolimbic system's role in analgesia, pain relief, and feelings of decreased motivation and depression as a result of chronic pain. Because chronic pain is among the most highly-cited reasons for decreased quality of life, advancing our understanding of the function and mechanism of the mesolimbic system may be critical to improving the quality of life for millions of people around the globe","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127967531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors Associated with Congenital Heart Disease in Patients Presenting to Aljalila Cardiology Clinic between January 2020- May 2020: A Case Control Study","authors":"Samah Alasrawi, Hessa Almansoori","doi":"10.47363/jcrrr/2021(3)143","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(3)143","url":null,"abstract":"Objective: To investigate the association of maternal diabetes, maternal smoking and syndromes with congenital heart disease (CHD) in patients attending Aljalila cardiology clinic between January 2020 and May of 2020. Methods: A case control study to assess the association of maternal diabetes, maternal smoking and syndromes with CHD. All patients that presented to the clinic between January 2020 and May of 2020 were included. An interviewer administered questionnaire was used to record the presence of maternal diabetes, maternal smoking, and the type of syndrome and type of CHD. Patients with CHD were included in the case group and patients who did not have CHD were in the control group. Age, gender, and nationality were also collected from the hospital records. Fisher exact test and logistic regression was used to analyze the results. Results: A total of 177 cases and 211 controls were recruited. All the risk factors increase the risk of CHD, with maternal diabetes (OR 6.3, 95% CI 2.7-14.6) having the strongest association, then syndromes (OR 5.1, 95% CI 2.3-11.3) and lastly maternal smoking (OR 4.0, 95% CI 1.0-16.3). The most common type of CHD is ventricular septal defect. Conclusion: Maternal diabetes, maternal smoking and syndromes are significant risk factors of CHD in children visiting Aljalila cardiology clinic. Action needs to be taken in order to decrease these risk factors and so, decrease the incidence of CHD in the future. Clearly, more research is needed in order to identify other risk factors for patients in the United Arab Emirates (UAE)","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127605656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolated Cleft of the Posterior Mitral Leaflet in 8 Year Old Patient","authors":"Merjema Karavdić, Herzegovina, M. Halimić","doi":"10.47363/jcrrr/2021(2)145","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(2)145","url":null,"abstract":"Cleft of the mitral valve is a rare cause of the congenital mitral regurgitation. Isolated cleft is uncommon finding and is more often found associated with some form of endocardial cushion defect. Cleft of the septal leaflet is found much more often than the defect in the posterior leaflet. Mitral clefts can extend to the mitral annulus or they can be less ''deep'' and show only minor regurgitation. Clinical importance of the isolated cleft of the mitral valve (ICMV) is that it can be successfully corrected by surgery and that it can have good long-term results.","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122217090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The “Depression and Elevation” Of ST Segment Settle Down As Momentary “Up and Down “ Of Architect of Artefact : A Case Report Of COVID-19 Patient","authors":"Anurodh Dadarwal, Sudeep Kumar","doi":"10.47363/jcrrr/2021(3)146.","DOIUrl":"https://doi.org/10.47363/jcrrr/2021(3)146.","url":null,"abstract":"A young male was admitted with diagnosis of Covid-19 SARS infection and was having fever, cough & non-cardiac chest pain. There was no past history of cardiac symptoms and physical examination was unremarkable. His vitals were stable. His ECG showed ST elevation and Tall but notched T wave in V3 and ST depression in inferior and lateral leads. Carefully looking these manifestations, they seem the artifacts based on their ECG features and history of the patient. ECG was repeated removing all possible sources of technical errors for these ECG manifestations which showed normal ECG confirming the diagnosis of artifactual ECG. Patient was discharged uneventfully. Recognition of ECG artifact and their technical causes is necessary to avoid inappropriate management.","PeriodicalId":152005,"journal":{"name":"Journal of Cardiology Research Review & Reports","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122574909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}