A. Lamas, P. Regal, Laura Sanjulián, Aroa Lopez-Santamarina, C. Franco, A. Cepeda
{"title":"An Overview of Salmonella Biofilms and the Use of Bacteriocins and Bacteriophages as New Control Alternatives","authors":"A. Lamas, P. Regal, Laura Sanjulián, Aroa Lopez-Santamarina, C. Franco, A. Cepeda","doi":"10.5772/INTECHOPEN.98208","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.98208","url":null,"abstract":"Salmonella is a major food-borne pathogen around the world. In the European Union (EU), this pathogen is responsible of more than 90,000 human cases of salmonellosis every year. Salmonellosis in normally linked to the consumption of contaminated food, especially poultry products as meat, eggs and the products elaborated with them. Several control measures have been implemented in the EU to reduce the prevalence of Salmonella in the food chain. However, the ability of Salmonella to form biofilm along the food chain difficult its eradication. Also, ineffective cleaning and disinfection measures favors biofilm formation. The widespread use of biocides along the food chain has led to the emergence of resistant Salmonella strains. Therefore, it is necessary to look for alternatives to biocides to eradicate Salmonella biofilms. In this chapter we evaluate the use of bacteriocins and bacteriophages and their derivatives as a new alternative to eliminate Salmonella biofilms along the food chain.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115393515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rohit Mishra, Y. Tan, A. A. El-Aal, Chandrajit Lahiri
{"title":"Computational Identification of the Plausible Molecular Vaccine Candidates of Multidrug-Resistant Salmonella enterica","authors":"Rohit Mishra, Y. Tan, A. A. El-Aal, Chandrajit Lahiri","doi":"10.5772/INTECHOPEN.95856","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.95856","url":null,"abstract":"Salmonella enterica serovars are responsible for the life-threatening, fatal, invasive diseases that are common in children and young adults. According to the most recent estimates, globally, there are approximately 11–20 million cases of morbidity and between 128,000 and 161,000 mortality per year. The high incidence rates of diseases like typhoid, caused by the serovars Typhi and Paratyphi, and gastroenteritis, caused by the non-typhoidal Salmonellae, have become worse, with the ever-increasing pathogenic strains being resistant to fluoroquinolones or almost even the third generation cephalosporins, such as ciprofloxacin and ceftriaxone. With vaccination still being one of the chosen methods of eradicating this disease, identification of candidate proteins, to be utilized for effective molecular vaccines, has probably remained a challenging issue. In our study here, we portray the usage of computational tools to analyze and predict potential vaccine candidate(s) for the multi-drug resistant serovars of S. enterica.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132757620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anisha M. Thanki, Steven P T Hooton, A. Gigante, R. Atterbury, M. Clokie
{"title":"Potential Roles for Bacteriophages in Reducing Salmonella from Poultry and Swine","authors":"Anisha M. Thanki, Steven P T Hooton, A. Gigante, R. Atterbury, M. Clokie","doi":"10.5772/INTECHOPEN.96984","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96984","url":null,"abstract":"This chapter discusses application of natural parasites of bacteria, bacteriophages (phages), as a promising biological control for Salmonella in poultry and swine. Many studies have shown phages can be applied at different points from farm-to-fork, from pre to post slaughter, to control the spread of Salmonella in the food chain. Pre-slaughter applications include administering phages via oral gavage, in drinking water and in feed. Post slaughter applications include adding phages to carcasses and during packaging of meat products. The research discussed in this chapter demonstrate a set of promising data that relate to the ability of phages to reduce Salmonella colonisation and abundance. Collectively the studies support the viability of phage as antimicrobial prophylactics and therapeutics to prevent and control Salmonella in the food chain.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122645828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enteric Fever in Primary Care","authors":"Abdulmaleek Idanesimhe Sado, Aduke Oluwambe Sado","doi":"10.5772/INTECHOPEN.96047","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96047","url":null,"abstract":"Enteric fever is a bacterial infection caused by Salmonella typhi and paratyphi. It is endemic in many parts of Africa and South Asia where there is poor access to safe portable water and below par food quality assurance. It is important to ensure prompt recognition, diagnosis and management of symptoms to forestall complications. Due to the rising global burden, significant effort has to be made to improve primary care services like vaccination, antimicrobial stewardship and encouragement of hygiene measures. Hence, it is imperative to be aware of its current burden and options available in primary care for its prevention and treatment.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124730705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-Typhoidal Salmonellosis: A Major Concern for Poultry Industry","authors":"Mamta Pandey, Emmagouni Sharath K. Goud","doi":"10.5772/INTECHOPEN.96400","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96400","url":null,"abstract":"Salmonella is the most important gastrointestinal pathogen distributed ubiquitously. The major serovars involved in Non-typhoidal salmonellosis are S. Typhimurium and S. Enteritidis. In the viewpoint of ban in the export and import of the Salmonella contaminated poultry food and poultry products, the need for rapid detection and mitigation of Salmonella has increased mani-folds. The major problem associated with its control is the growing incidence of antimicrobial resistance, which has been reported worldwide in the recent years. From causing self limiting gastroenteritis they have found to be responsible for several fatal diseases like endocarditis, meningitis, lung infestations, appendicitis, pneumonia, and cerebral abscess in human beings. Targeting several proteins such as adhesive proteins, lipoproteins, outer membrane proteins (Omps) etc. as vaccine candidates may pave a way in its control. So, continuous monitoring using one health approach and development of effective treatment and control strategies are critical.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128964760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Virulence Factors of Salmonella Typhi","authors":"N. S. Al-Khafaji, A. Al-Bayati, H. Al-Dahmoshi","doi":"10.5772/INTECHOPEN.95587","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.95587","url":null,"abstract":"S. Typhi is an enteric bacillus which belongs,to the genus Salmonella in the family Enterobacteriacaea and it is a multi–organs pathogen which inhibits the lymphatic tissues of the small intestine, liver, spleen, and blood stream of infected humans.S.Typhi has a mixture of features that make it an efficient pathogen. This species contains an endotoxin that is characteristic of Gram-negative organisms, as well as the virulence-enhancing Vi antigen. Many of the S. Typhi virulence factors are clustered in some areas of the chromosome known as Salmonella pathogenicity islands (SPI), such as adhesion, invasion, and toxin genes. A protein known as invasin that permits non-phagocytic cells is also produced and excreted by the bacterium., Where it is capable of intracellular living. The oxidative burst of leukocytes may also be inhibited, making innate immune reaction ineffective.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123076933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Rubira, L. Figueras, J. C. Jiménez, M. R. D. Arcaute, H. Ruíz, J. Ventura, D. Lacasta
{"title":"Salmonella enterica subsp. diarizonae Serotype 61:k:1:5:(7) a Host Adapted to Sheep","authors":"I. Rubira, L. Figueras, J. C. Jiménez, M. R. D. Arcaute, H. Ruíz, J. Ventura, D. Lacasta","doi":"10.5772/INTECHOPEN.95513","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.95513","url":null,"abstract":"Salmonella genus is widely distributed in nature and causes a spectrum of diseases in man and animals. Salmonella enterica subsp. diarizonae serotype 61: k: 1,5, (7) (SED) is a host adapted to sheep and its presence as saprophytic bacteria in sheep has been described in different countries. Several studies performed in abattoirs reported the presence of SED in healthy sheep in the intestinal content and also in the respiratory tract. In addition, this microorganism has also been isolated from nostril and faecal samples in healthy live animals. For this reason, this microorganism is considered well adapted to sheep, behaving normally these animals as asymptomatic carriers. However, SED has also been reported causing health disorders such as chronic proliferative rhinitis in adult sheep, abortions, testicular lesions in rams or alimentary tract disorders in young animals. The zoonotic potential of this microorganism is also discussed.","PeriodicalId":151982,"journal":{"name":"Salmonella - a Challenge From Farm to Fork [Working Title]","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133726763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}