Journal of Behavioral and Brain Science最新文献

{"title":"Altered microstructural connectivity of the arcuate fasciculus is related to language disability in children with autism spectrum disorder","authors":"Mika Kimura, Ryuzo Hanaie, I. Mohri, K. Kagitani-Shimono, M. Tachibana, Junko Matsuzaki, N. Fujita, Yoshiyuki Watanabe, M. Taniike","doi":"10.20821/JBS.42.0_21","DOIUrl":"https://doi.org/10.20821/JBS.42.0_21","url":null,"abstract":"","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"25 1","pages":"21-42"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84504134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children's behavioural problems are perceived differently by their teachers and parents : The Hamamatsu School Survey","authors":"Norihiro Sakurai, K. Tsuchiya, Katsuaki Suzuki, M. Wakuta, N. Takei, N. Mori","doi":"10.18910/26153","DOIUrl":"https://doi.org/10.18910/26153","url":null,"abstract":"Background: Studies have suggested that to","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"60 1","pages":"28-53"},"PeriodicalIF":0.0,"publicationDate":"2013-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76488310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An animal model of Parkinson's disease produced by rotenone intraperitoneal injection","authors":"Zhao-qiang Zhang, Xiao Sun, Xiang-lin Chi, Xianan Sun, Hong Jiang","doi":"10.20821/JBS.40.0_54","DOIUrl":"https://doi.org/10.20821/JBS.40.0_54","url":null,"abstract":"","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"34 8 1","pages":"54-65"},"PeriodicalIF":0.0,"publicationDate":"2013-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88211218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual perception of unstructured figures in patients with autism spectrum disorder : a preliminary study","authors":"Tomoko Muramatsu, Hideo Nakatani, M. Kikuchi, T. Munesue","doi":"10.18910/26148","DOIUrl":"https://doi.org/10.18910/26148","url":null,"abstract":"Ambiguous figures, sueh as the reversible figure of the girilold women 5 (Boring, 1930), have mspired an enormous amount ot research into the domain of visual perception. Howevet visual perception of unstructured figures, such as stains on walls, which contain no meanings themselves, has not been a main topic of research in healthy subjects or in subjects with autism spectrum disorder (ASD). The aims of this study were to obtain inkblot re$ponses characteristic of subjects with ASD (n = 36), to compare these response to those of healthy subjects (n = 50), and to assess whether these responses had any relevance to ASD trajts, as evaluated using standard questionnaires, such as the Autism-spectrum Quotient (AQ) and thg Empathy Quotient (EQ). Atl of the responses of each subject were scored Japan Brain Science Society NII-Electronic Library Service apanBrainScienceSociety ! ThistiHe / i,Iili, Sllil}Lesp\"cd ,. 'i\"1er`e it .l}.:.i.Ml.J...,iofBrainScience, March 30, 2013,Vol.40 using the Exner Comprehensive Scoring System, which is the standard method for evaluating responses to the Rorschach test. The scores of total responses were not different between the subjects with ASD and healthy subjects. Only the scores for the variable designated FM were significantly lower in ASD subjects compared to healthy subjects, indicating that the subjects perceived animals in motion in their visual perceptions of unstructured figures in inkblots. Furthermore, the FM scores demonstrated a significantly inverse correlation with the AQ scores and were $ignificantly coffelated with the EQ scores. Each variable of M indicated a response of humans in motion, with m indicating a response of inanimate in motion, Human indicating total responses conceming humans, and Animal indicating total responses conceming animals; these measurements were not ditferent between the two groups and 6 were not correlated with the scores on the AQ or the EQ. Based on this preliminary study, representations of animals in motion in visual perception may be a subject that could shed light on the biological relevance between unstructured figures and autism traits. Kfflf words ambiguous figure, autjsm phenotype, autism spectrum disordet illusion, inkblots of the Rorschach, unstructured figure, visuat perception lntroduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder that comprises autistic disorder, Aspergeris disorder, and pervasive developmental disorder not othenNise specified as designated in the i!2iegnnoshc end SlatAsifca/ ildlanua/ or nebnta/ avsotvlers Fbutth Eb(h)bn 7etrt y?evofston (DSM-tX--TR) (i]. Behavioral signs of ASD emerge between 6 and t2 months of age in the Japan Brain Science Society NII-Electronic Library Service apanBrainScienceSociety ' Th!stLlte , iiiill:i.iiS ',orsei,-II-l] d rcr,.PSC.J.,.,i.fBrainscie\"ce, March 30, 2013,Vol.40 form of a decline in social engagement, such as gazing at faces and social smiles t2]・ [3]. Moreover, the head circumference ","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"40 1","pages":"5-27"},"PeriodicalIF":0.0,"publicationDate":"2013-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88002563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of executive function using the Behavior Rating Inventory of Executive Function (BRIEF) and the Cambridge Neuropsychological Test Automated Battery (CANTAB) in young children with attention deficit/hyperactivity disorder, inattention type","authors":"Fumiyo Nagatani, Junko Matsuzaki, Moe Eto, K. Kagitani-Shimono, I. Mohri, M. Taniike","doi":"10.20821/JBS.39.0_5","DOIUrl":"https://doi.org/10.20821/JBS.39.0_5","url":null,"abstract":"Nagatani Fumiyo, Matsuzaki Junko, Eto Moe, Kagitani-Shimono Kuriko, Mohri Ikuko, Taniike Masako, Assessment of executive function using the Behavior Rating Inventory of Executive Function (BRIEF) and the Cambridge Neuropsychological Test Automated Battery (CANTAB) in young children with attention deficit/hyperactivity disorder, inattention type, Journai of Brain Science, 39, 5-21, 2012","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"34 1","pages":"5-21"},"PeriodicalIF":0.0,"publicationDate":"2013-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81003303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How the Brain Process Stimulus-Response Conflict? New Insights from Lateralized Readiness Potentials Scalp Topography and Reaction Times.","authors":"Marc E Lavoie,&nbsp;Johannes E A Stauder","doi":"10.4236/jbbs.2013.31014","DOIUrl":"https://doi.org/10.4236/jbbs.2013.31014","url":null,"abstract":"<p><p>Stimulus-Response Compatibility (SRC) refers to the fact that some tasks are performed easier and better than others because of the way stimuli and responses are paired with each other. To assess the brain responses to stimulus-response conflicts, we investigated the behavioral (accuracy and Reaction Times: RTs) as well as the physiological response (Lateralized Readiness Potentials: LRP) modulations in a positional blocked and a conditional mixed design in twelve university students. Results revealed that the performance was less accurate and the RTs, as well as the LRP onset, were delayed under the mixed conditional design. A greater compatibility effect was also noted on accuracy, RTs and LRP onset latency in the mixed design. Consistent with these findings, smaller peak activation at fronto-central areas suggests that more selective inhibition is needed in a mixed design context. Despite a smaller activation, the topographical distribution is similar in both designs. These results indicate that the translation time between stimulus- and response codes are greater under the mixed instruction, while the similar LRP topography suggests that common neural structures underlie LRPs in response to both type of designs.</p>","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"3 1","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2013-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006818/pdf/nihms3320.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32314567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statins Protect the Blood Brain Barrier Acutely after Experimental Intracerebral Hemorrhage.","authors":"Dongmei Yang,&nbsp;Robert A Knight,&nbsp;Yuxia Han,&nbsp;Kishor Karki,&nbsp;Jianfeng Zhang,&nbsp;Michael Chopp,&nbsp;Donald M Seyfried","doi":"10.4236/jbbs.2013.31010","DOIUrl":"https://doi.org/10.4236/jbbs.2013.31010","url":null,"abstract":"<p><strong>Objectives: </strong>The goal of this study was to measure the impact of simvastatin and atorvastatin treatment on blood brain barrier (BBB) integrity after experimental intracerebral hemorrhage (ICH).</p><p><strong>Methods: </strong>Primary ICH was induced in 27 male Wistar rats by stereotactic injection of 100 µL of autologous blood into the striatum. Rats were divided into three groups (n= 9/group): 1) oral treatment (2 mg/kg) of atorvastatin, 2) oral treatment (2 mg/kg) simvastatin, or 3) phosphate buffered saline daily starting 24-hours post-ICH and continuing daily for the next 3 days. On the fourth day, the animals underwent magnetic resonance imaging (MRI) for measurements of T_1sat (a marker for BBB integrity), T₂ (edema), and cerebral blood flow (CBF). After MRI, the animals were sacrificed and immunohistology or Western blotting was performed.</p><p><strong>Results: </strong>MRI data for animals receiving simvastatin treatment showed significantly reduced BBB dysfunction and improved CBF in the ICH rim compared to controls (<i>P</i><0.05) 4 days after ICH. Simvastatin also significantly reduced edema (T₂) in the rim at 4 days after ICH (<i>P</i><0.05). Both statin-treated groups demonstrated increased occludin and endothelial barrier antigen levels within the vessel walls, indicating better preservation of BBB function (<i>P</i><0.05) and increased number of blood vessels (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>Simvastatin treatment administered acutely after ICH protects BBB integrity as measured by MRI and correlative immunohistochemistry. There was also evidence of improved CBF and reduced edema by MRI. Conversely, atorvastatin showed a non-significant trend by MRI measurement.</p>","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"3 1","pages":"100-106"},"PeriodicalIF":0.0,"publicationDate":"2013-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583226/pdf/nihms434278.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31281382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"5-HT_2A Receptor Activation Normalizes Exaggerated Fear Behavior in <i>p</i>-Chlorophenylalanine (PCPA)-Treated Rats.","authors":"Cathryn R Hughes,&nbsp;Lee Tran,&nbsp;N Bradley Keele","doi":"10.4236/jbbs.2012.24053","DOIUrl":"https://doi.org/10.4236/jbbs.2012.24053","url":null,"abstract":"<p><p>Deficits in serotonin (5-hydroxytryptamine, 5-HT) neurotransmission are implicated in abnormal emotional behaviors such as aggression, anxiety, and depression. However, the specific 5-HT receptor mechanisms involved are not well understood. The role of 5-HT₂ receptors in fear potentiated startle, (FPS) was examined in rats chronically treated with <i>p</i>-chlorophenylalanine (PCPA) to reduce brain 5-HT. PCPA-treated rats show an enhanced magnitude of FPS. Systemic administration of the 5-HT₂ receptor agonist (±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride (DOI) reduced FPS in both PCPA-treated and saline (SAL)-treated control animals, normalizing the exaggerated fear response in PCPA-treated rats. In both SAL- and PCPA-treated animals, the DOI-induced reduction of learned fear was reversed by the 5-HT₂ antagonist ketanserin, but not by the 5-HT_2B/2C antagonist SB 206553. Together, these findings suggest 5-HT_2A receptors are critical regulators of learned fear, and that 5-HT_2A receptors may be an important pharmacological target to normalize exaggerated learned fear resulting from chronic 5-HT-ergic disruption.</p>","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"2 4","pages":"454-462"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003617/pdf/nihms-1874699.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9109221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explore the method of observing dynamic changes in microcirculation of rabbit's duodenal mucosal villi with a red color coordinate following brainstem hemorrhage","authors":"Xuelong Jin, Bin Liang, Fei-Ge Wang, Zhiwen Zhang","doi":"10.20821/JBS.39.0_32","DOIUrl":"https://doi.org/10.20821/JBS.39.0_32","url":null,"abstract":"","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"54 1","pages":"32-40"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80185817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stem cell transplantation strategies following traumatic brain injury","authors":"Xingju Liu","doi":"10.20821/JBS.39.0_41","DOIUrl":"https://doi.org/10.20821/JBS.39.0_41","url":null,"abstract":"","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"27 1","pages":"41-50"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73750195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}