{"title":"Treatment challenges in childhood cancer","authors":"B. Wilson","doi":"10.15406/jcpcr.2018.09.00368","DOIUrl":"https://doi.org/10.15406/jcpcr.2018.09.00368","url":null,"abstract":"","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83817961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iel Marciano de Moraes-Filho, Maria Rubiene Timoteo Nery, Sheila da Silva Santos, María Fern, A. R. Proença, Carla Chiste Tomazoli Santos, R. M. Silva
{"title":"Knowledge level and prevetive strategies on penile cancer in health area degree students","authors":"Iel Marciano de Moraes-Filho, Maria Rubiene Timoteo Nery, Sheila da Silva Santos, María Fern, A. R. Proença, Carla Chiste Tomazoli Santos, R. M. Silva","doi":"10.15406/JCPCR.2018.09.00370","DOIUrl":"https://doi.org/10.15406/JCPCR.2018.09.00370","url":null,"abstract":"Penile cancer, although considered rare in developed countries, presents relevant incidence rates in Brazil. The increase in neoplasias in the male population is due to the adjustment of multiple factors, some of them environmental, genetic and lifestyle, such as smoking, sedentary lifestyle, poor diet, obesity, alcoholism, resulting from exposure to infectious agents, without condoms and with multiple partners.1,2 This amount of factors increases the risk of development of certain types of cancer, and the single reduction of only one of them may be limited to cover the effectiveness of precautionary actions.2 Amidst the clinical forms of cancers that often affect the male population, I emphasize penile cancer. An uncommon neoplasm in developed countries, unlike what occurs in regions of low socioeconomic class, as in most of the Brazilian Northeast.3 In Brazil, penile carcinoma is the fourth most common type of male cancer in the North and Northeast, simultaneously 5.7 and 5.3%; in the CenterWest region takes eighth place and in the South and Southeast regions and occupies the top ten male neoplasms.4","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"2010 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78586051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conventıonal and targeted therapy in metastatıc colorectal cancer","authors":"A. M. Sedef, A. Sümbül","doi":"10.15406/jcpcr.2018.09.00369","DOIUrl":"https://doi.org/10.15406/jcpcr.2018.09.00369","url":null,"abstract":"Colorectal cancer is the second leading cause of death in the United States among all cancers.1 Approximately 20% to 25% of colorectal cancer patients are diagnosed with liver metastasis at the time of initial diagnosis and a further 40% to 50% of patients will develop liver metastasis within 3 years from initial diagnosis.2,3 Metastatic colorectal cancer is generally not curable disease. However, a subset of patients with isolated metastases to liver and/or lung are potentially curable with local therapies such as surgery. Treatment is systemic chemotherapy with purpose palliation and control of symptoms, control of tumor growth for patients with non-curable metastatic colorectal cancer. The median survival is 5 to 6 months for metastatic colorectal cancer patients without specific therapy. After fluorouracil plus leucovorin (LV) therapy median survival is approximately 1 year for these patients. The addition of oxaliplatin and irinotecan to the fluorouracil and LV therapy provided an improvement in median survival to nearly 20 months since the year 2000. Finally new pathways has been defined and new therapies started to use which targeted these new pathways. Overall survival was increased with these novel agents such as bevacisumab, cetuximab, panitumumab, other TKİs and immunotherapies.4","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89783049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toluleke Oloruntobi Famuyiwa, Joubin Jebelli, James Kwasi Kumi Diaka, W. Asghar
{"title":"Interaction between 3-Bromopyruvate and SC-514 in prostate cancer treatment","authors":"Toluleke Oloruntobi Famuyiwa, Joubin Jebelli, James Kwasi Kumi Diaka, W. Asghar","doi":"10.15406/JCPCR.2018.09.00367","DOIUrl":"https://doi.org/10.15406/JCPCR.2018.09.00367","url":null,"abstract":"Prostate cancer (PCa) still remains a medical challenge to the world1 and it is becoming a common disease in the world.2 PCa account for 15% of all cancers in men worldwide.3 Prostate cancer is the most prevalent among the cancer related diseases and the second leading cause of cancer related death in USA.4 Prostate cancer poses a major economic limitation in humans. The economic limitation on patients makes prostate cancer one of the deadliest diseases. Patients with advanced stage of the disease have a low quality of life; they constantly visit the hospital for extremely expensive treatments. Regardless of the costly treatment of prostate cancer, there is life threatening transformations in the patient’s body system.5‒7","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"2006 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82575137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of genotoxic and cytotoxic effects of acrylamide in HEK293 cell line","authors":"F. Çelik, T. Cora, A. Yiğin","doi":"10.15406/jcpcr.2018.09.00365","DOIUrl":"https://doi.org/10.15406/jcpcr.2018.09.00365","url":null,"abstract":"Until 2000, the knowledge that acrylamide was not formed naturally but could be chemically synthesized was accepted. Tareke and colleagues from Stockholm University have announced to the scientific world that abundant amounts of acrylamide are formed when food is cooked at temperatures above 120°C.1,2 The amount of acrylamide present during the cooking process is increasing in direct proportion to the temperature and duration of exposure. The first study of how much acrylamide we take on a daily basis after being detected in acrylamide-cooked foods was done in the Netherlands. According to this study, human subjects fed with foods cooked at high temperatures were found to take 0.5mg/kg of acrylamide on average per day depending on their body weight.3 However, in recent studies it has been reported that this amount is 0.27μg/ kg for female individuals and 0.36μg/kg for male individuals in the Dutch population.4 Similar to these results, in the American population study this amount was found to be 0.44μg/kg per person per day.5","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80864113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expatriates with cancer diagnosis in the United Arab Emirates, hanging on the edge","authors":"H. Al-Shamsi","doi":"10.15406/JCPCR.2018.09.00364","DOIUrl":"https://doi.org/10.15406/JCPCR.2018.09.00364","url":null,"abstract":"","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73610675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On cancer-fighting nanorobots","authors":"A. Fymat","doi":"10.15406/jcpcr.2018.09.00363","DOIUrl":"https://doi.org/10.15406/jcpcr.2018.09.00363","url":null,"abstract":"There have recently been two major developments and advances in this field, namely1 the construction of an autonomous DNA nanorobot as an intelligent drug delivery and therapeutic system that responds to molecular triggers in vivo and2 the successful programming of autonomous nanorobots to shrink tumors by cutting-off their blood supply (an antiangiogenic approach, see Fymat).3 The structures are built from DNA that can self-fold in all sorts of shapes and sizes.","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81112273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Saldera, Rubnawaz Baloch, Naveed Ahmed, T. Mahmood, S. Kadri
{"title":"Role of Cyber knife Radiosurgery in pituitary mass and improvement in growth hormone levels","authors":"K. Saldera, Rubnawaz Baloch, Naveed Ahmed, T. Mahmood, S. Kadri","doi":"10.15406/JCPCR.2018.09.00362","DOIUrl":"https://doi.org/10.15406/JCPCR.2018.09.00362","url":null,"abstract":"Pituitary adenoma is one of the most common benign tumors of central nervous system, 1,2 accounting 10% of intracranial tumors.3,4 An estimated prevalence of asymptomatic small pituitary tumor is 16.7% (14.4% in autopsy and 22.5% in radiologic studies).3,4 Pituitary adenoma prevalence is based on recent crosssectional study is estimated to be 80-90 per 100,000. 30% of pituitary tumors are non-secretary and 70% secrets greater amount of pituitary hormones. In secretary adenomas 60% prolactinomas, 20% growth hormone secreting tumors and with decreasing frequency is adrenocorticotrophic hormone (ACTH) secreting tumors and thyroid stimulating hormone (TSH)) secreting tumors (10). Pituitary adenoma can be micro or macroadenoma by cutoff size of 10mm. Tumors exceeding 30-40mm are giant adenoma. Most tumors are benign, but 20-55% shows invasion.5,6","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83230830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Family functionality and coping strategies in patients with breast cancer","authors":"CS Concepción Ramón López,, M. Martínez Cortés","doi":"10.15406/jcpcr.2018.09.00361","DOIUrl":"https://doi.org/10.15406/jcpcr.2018.09.00361","url":null,"abstract":"The family is a system variable structure in which its members interact, grow and develop throughout life; always subject to external factors that influence positively or negatively on its composition and interactions so that family functioning is the ability to face and overcome each of the stages of the life cycle and crises being experienced. Within the study of family functioning has become very important to be demonstrated in several studies the influence on the health of its members.1–5 The assessment of family functionality in family medicine has specific characteristics that differentiate it from which can be performed by other disciplines, because it has the fundamental purpose of comprehensively understanding the context in which the pathology is produced by allowing reorient their treatment different solutions to those traditionally offered, contributing elements to the biopsychosocial vision that characterizes familiar3,4 medical attention. Breast cancer is suffering from a stressful event that threatens significantly in different areas and decay can occur daily activities and cause negative emotional states in patients; so it is important to evaluate and understand the impact of the disease and treatment on perceived welfare of the patient; that assessment should be comprehensive and individualized to each woman considering the physical, social and psicológico6,7 appearance.","PeriodicalId":15185,"journal":{"name":"Journal of Cancer Prevention & Current Research","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72678641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}