Journal of Arrhythmia最新文献

{"title":"Electrogram Transition Patterns During Atrial Antitachycardia Pacing-Mediated Termination","authors":"Kosuke Nakasuka,&nbsp;Youmei Sakurai,&nbsp;Satoru Sekimoto,&nbsp;Hirokazu Naganawa,&nbsp;Kento Mori,&nbsp;Toshihiko Goto,&nbsp;Takeshi Suzuki,&nbsp;Yoshimasa Murakami,&nbsp;Yoshihiro Seo","doi":"10.1002/joa3.70472","DOIUrl":"10.1002/joa3.70472","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Atrial antitachycardia pacing (aATP) reduces atrial tachyarrhythmia (ATA) burden, yet the electrogram dynamics after aATP delivery remain uncharacterized. We sought to characterize electrogram transition patterns during aATP-mediated ATA termination by clinician review of intracardiac electrograms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We performed a multicenter retrospective study of patients with dual-chamber cardiac implantable electronic devices with aATP activated. Stored intracardiac atrial electrograms from aATP-terminated ATA episodes were analyzed by electrophysiologists using predefined criteria to classify pre-aATP electrogram regularity and post-aATP transition patterns.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 119 patients with aATP activated, 83 had device-detected ATAs. Stored electrograms were available in 38 patients (1641 aATP-terminated episodes), of whom 15 had prior catheter ablation for ATAs and 23 had no prior ablation. We identified six electrogram transition patterns. Regardless of pre-aATP regularity, irregular post-aATP activity was the most common pattern preceding termination (47% in regular and 63% in irregular pre-aATP episodes, <i>p</i> &lt; 0.001). Episodes with irregular pre-aATP activity took longer to terminate than those with regular pre-aATP activity (median 13 vs. 9 s, <i>p</i> &lt; 0.001). At the episode level, the regular-to-irregular pattern was more common in patients with prior ATA catheter ablation than those without (39% vs. 22%, <i>p</i> &lt; 0.001), although this was not significant after accounting for within-patient clustering (<i>p</i> = 0.11).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Regardless of pre-aATP electrogram regularity, irregular post-aATP activity was the most common pattern preceding termination. This association is consistent with pacing-induced destabilization, although alternative explanations cannot be excluded. Episodes with irregular pre-aATP activity took longer to terminate, suggesting that pre-aATP regularity is associated with the electrogram dynamics preceding termination.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “R1 Prognostic Significance of T-Wave Amplitude Variability for Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis”","authors":"","doi":"10.1002/joa3.70493","DOIUrl":"10.1002/joa3.70493","url":null,"abstract":"<p>\u0000 <span>Y. Sobue</span>, <span>K. Takeda</span>, <span>M. Amino</span>, <span>K. Yoshioka</span>, <span>T. Ichikawa</span>, and <span>E. Watanabe</span>, “ <span>R1 Prognostic Significance of T-Wave Amplitude Variability for Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis</span>,” <i>Journal of Arrhythmia</i> <span>42</span>, no. <span>4</span> (<span>2026</span>): e70411, https://doi.org/10.1002/joa3.70411.\u0000 </p><p>The title of the article “R1 Prognostic Significance of T-Wave Amplitude Variability for Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis” is corrected to “Prognostic Significance of T-Wave Amplitude Variability for Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis”.</p><p>The online version of the article is corrected accordingly.</p><p>We apologize for this error.</p>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reverse Ratchet Syndrome With Intracardiac Looping","authors":"Gen Matsuura,&nbsp;Hidehira Fukaya,&nbsp;Tomoharu Yoshizawa,&nbsp;Atsuhiko Sugimoto,&nbsp;Junya Ako","doi":"10.1002/joa3.70489","DOIUrl":"10.1002/joa3.70489","url":null,"abstract":"<p>Intracardiac lead looping developed 7 years after ICD implantation due to reverse Ratchet syndrome. Despite marked radiographic abnormalities, device parameters remained stable and the patient was asymptomatic. Inadequate fixation of the generator and lead sleeves likely contributed to lead advancement. Surgical revision with secure fixation prevented recurrence, highlighting the importance of proper device fixation and long-term imaging follow-up to detect delayed lead malposition.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Resynchronization as an Enabler of ARNI Efficacy: Insights From a Real-World Cohort","authors":"Amato Santoro,&nbsp;Laura Spaccaterra,&nbsp;Maurizio Collantoni,&nbsp;Claudia Baiocchi,&nbsp;Benedetta Maria Natali,&nbsp;Stefano Lunghetti,&nbsp;Antonio Pagliaro,&nbsp;Niccolò Manetti,&nbsp;Francesco Morrone,&nbsp;Massimo Fineschi,&nbsp;Alberto Palazzuoli","doi":"10.1002/joa3.70488","DOIUrl":"10.1002/joa3.70488","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Sacubitril/valsartan (ARNI) improves outcomes in heart failure with reduced ejection fraction (HFrEF). In patients undergoing cardiac resynchronization therapy (CRT), the potential synergy between device-based and pharmacological strategies remains underexplored.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The aim of this study was to assess the effect of ARNI therapy on reverse remodeling, clinical response, and cardiovascular events at 1 year in CRT recipients, in order to clarify the potential synergistic role of pharmacological and device-based strategies. A retrospective cohort of 194 consecutive CRT patients was analyzed, of whom 65 (33.5%) received ARNI. Echocardiographic response was defined as an increase in LVEF &gt; 5% or ≥ 15% reduction in LV end-systolic volume at 12 months; clinical response as an improvement of at least one NYHA class. The primary endpoint was echocardiographic response. Device-detected remote monitoring heart failure (RM-HF) events were pre-specified as the key time-to-event endpoint, while mortality and HF hospitalization were exploratory.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Baseline characteristics were comparable, although systolic blood pressure was higher in ARNI recipients. At 12 months, ARNI therapy was associated with greater reverse remodeling (ΔLVEF 14.4% ± 10.2% vs. 10.8% ± 11.0%, <i>p</i> = 0.04). Rates of echocardiographic (68% vs. 67%) and clinical response (68% vs. 74%) were similar. Mortality and HF hospitalization did not differ significantly. In contrast, ARNI recipients showed fewer RM-HF events, with higher event-free survival among echocardiographic responders (95.7% vs. 82.6%; log-rank <i>p</i> = 0.021, <i>q</i> = 0.042) and clinical responders (93.4% vs. 85.3%; <i>p</i> = 0.040, <i>q</i> = 0.040).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In this real-world CRT cohort, ARNI therapy enhanced reverse remodeling and reduced subclinical congestion events detected by remote monitoring. These findings support a synergistic interaction between CRT and ARNI, where resynchronization provides the substrate for pharmacological efficacy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Sinus Electrogram Changes After Cavotricuspid Isthmus Ablation for Typical Atrial Flutter: What Is the Mechanism?","authors":"Shun Nakamura,&nbsp;Takashi Nakashima,&nbsp;Takahisa Ido,&nbsp;Shigekiyo Takahashi,&nbsp;Takuma Aoyama","doi":"10.1002/joa3.70475","DOIUrl":"10.1002/joa3.70475","url":null,"abstract":"<p>Typical atrial flutter was terminated and sinus rhythm was restored. We discussed the mechanism of changes in the coronary sinus atrial electrograms.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and Demographic Disparities Among Adults With Sudden Cardiac Death and Diabetes Mellitus in the United States: A Nationwide Analysis","authors":"Taha Mehmood,&nbsp;Muhammad Abdullah,&nbsp;Masab Ali,&nbsp;Amina Jamil,&nbsp;Muhammad Husnain Ahmad,&nbsp;Muhammad Mujtaba Tariq,&nbsp;Areej Asif,&nbsp;Sunnia Khan,&nbsp;Moeez Ahmad Saeed,&nbsp;Muhammad Hassan,&nbsp;Aasim Ali,&nbsp;Muhammad Umar Shahid,&nbsp;Shahzaib Ihsan,&nbsp;Muhammad Usama Yasin,&nbsp;Usama Siddique","doi":"10.1002/joa3.70467","DOIUrl":"10.1002/joa3.70467","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Sudden cardiac death (SCD) represents a major cause of cardiovascular mortality, with diabetes mellitus (DM) significantly increasing susceptibility. However, long-term national trends and demographic disparities in SCD among decedents with co-documented SCD and DM remain insufficiently characterized.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a retrospective analysis using the CDC WONDER database from 1999 to 2020. Adults with SCD and DM listed on death certificates were included. Age-adjusted mortality rates (AAMRs) per 100 000 population were calculated and stratified by sex, age group, race/ethnicity, census region, state, and urbanization status. Temporal trends were assessed using annual percent changes (APCs), with <i>p</i> &lt; 0.05 considered statistically significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 51 756 deaths among decedents with co-documented SCD and DM were identified. Overall AAMR increased from 1.29 in 1999 to 1.46 in 2020 (APC +0.46%, <i>p</i> = 0.012). Men had significantly higher mortality than women. Older adults (≥ 75 years) exhibited the highest mortality burden, though relative increases were notable in younger groups. Black individuals had the highest mortality, with a sharp rise in 2020. Rural populations experienced higher mortality than urban counterparts, with significant upward trends. Southern states demonstrated the highest regional burden.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The population-level burden of co-documented SCD and DM in the United States has increased modestly over the past two decades, with significant demographic and geographic disparities. Targeted public health interventions and equitable cardiovascular risk management are urgently needed to reduce these disparities.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13628289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Procedural Efficiency and Clinical Outcomes of a Region-Specific Radiofrequency Ablation Strategy for Pulmonary Vein Isolation","authors":"Etel Silva,&nbsp;Joaquín Alba-Camacho,&nbsp;Rafael Fernández-Rivero,&nbsp;Lucas Cano-Calabria,&nbsp;Iván Lobo-Torres,&nbsp;Saman Golmaryami,&nbsp;Ana María Solano-Mulero,&nbsp;Juan Fernández-Armenta","doi":"10.1002/joa3.70468","DOIUrl":"10.1002/joa3.70468","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>High-power short-duration radiofrequency ablation improves procedural efficiency during pulmonary vein isolation (PVI), but concerns remain regarding lesion transmurality and posterior wall collateral injury. We evaluated whether a region-specific ablation strategy was associated with improved procedural efficiency without a detected difference in acute efficacy or 12-month arrhythmia recurrence compared with conventional ablation index-guided PVI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this retrospective single-center study, 250 patients undergoing first-time PVI were treated with either ablation index-guided ablation or a region-specific strategy using very high-power short-duration applications on the posterior wall and ablation index-guided lesions on the anterior wall. The primary endpoint was first-pass isolation, analyzed per pulmonary vein using generalized estimating equations to account for within-patient clustering. Secondary endpoints included procedural efficiency, peri-procedural safety, and 12-month arrhythmia recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>First-pass isolation was achieved in 919 of 1 000 pulmonary veins (91.9%): 454 of 500 veins (90.8%) with the region-specific strategy and 465 of 500 veins (93.0%) with ablation index-guided ablation, with no significant between-group difference (OR, 0.74; 95% CI, 0.41–1.34; <i>p</i> = 0.322). The region-specific strategy was associated with shorter procedure duration, ablation time, radiofrequency time, fluoroscopy time, and lower radiation dose (all <i>p</i> &lt; 0.001). Acute complications occurred in 4 patients (1.6%). At 12 months, arrhythmia recurrence occurred in 43 patients (17.2%), with no detected difference between strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A region-specific ablation strategy improved procedural efficiency without a detected difference in first-pass isolation or 12-month arrhythmia recurrence compared with ablation index-guided PVI.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulsed-Field Ablation for Atrial Fibrillation in Partial Anomalous Pulmonary Venous Return With Right Atrial Drainage of Both Right Pulmonary Veins","authors":"Keisho Kurokawa,&nbsp;Hiroshi Kawakami,&nbsp;Tomoki Fujisawa,&nbsp;Momo Taira,&nbsp;Rikako Horie,&nbsp;Shunsuke Tamaki,&nbsp;Osamu Yamaguchi","doi":"10.1002/joa3.70485","DOIUrl":"10.1002/joa3.70485","url":null,"abstract":"<p>Pulsed-field ablation was safely performed in a patient with atrial fibrillation and partial anomalous pulmonary venous return. Electroanatomical mapping defined the sinus node region and confirmed sufficient distance from anomalous right pulmonary vein ablation sites, enabling successful isolation.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leadless Atrial Pacemaker Implantation at a Nonstandard Site After Unsuccessful Conventional Atrial Placement","authors":"Morio Ono,&nbsp;Taku Asano,&nbsp;Toshihiko Gokan,&nbsp;Yuya Nakamura,&nbsp;Junko Honye","doi":"10.1002/joa3.70486","DOIUrl":"10.1002/joa3.70486","url":null,"abstract":"<p>After unsuccessful implantation at the conventional right atrial appendage site, an atrial leadless pacemaker was implanted at the high right atrial septum. Electrical parameters were maintained during 6-month follow-up.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stepwise Localization of Non-Pulmonary-Vein Ectopy Using Cycle-Length-Based Activation Map Separation and Local Electrogram Morphology on the Affera System","authors":"Suguru Nishiuchi,&nbsp;Shingo Yoshimura,&nbsp;Takehito Sasaki,&nbsp;Kohki Nakamura,&nbsp;Shigeto Naito","doi":"10.1002/joa3.70484","DOIUrl":"10.1002/joa3.70484","url":null,"abstract":"<p>On the Affera system, a single voltage-map dataset containing both sinus and ectopic beats, collected without rhythm-specific settings, can be separated by cycle length (coupling interval) into SR and PAC activation maps. Stepwise filtering by activation threshold (voltage-per-second, excluding far-field potentials) and close-unipolar QS-like morphology then precisely localizes the ectopic origin.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"42 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}