Journal of biomedical materials research最新文献_第6页

Fatigue properties of acrylic bone cements: review of the literature. 丙烯酸骨水泥的疲劳性能:文献综述。

Journal of biomedical materials research Pub Date : 1988-04-01

W Krause, R S Mathis

引用次数: 0

Wear, creep, and frictional heating of femoral implant articulating surfaces and the effect on long-term performance--Part II, Friction, heating, and torque. 股骨植入物关节表面的磨损、蠕变和摩擦加热及其对长期性能的影响——第二部分，摩擦、加热和扭矩。

Journal of biomedical materials research Pub Date : 1988-04-01

J A Davidson, G Schwartz, G Lynch, S Gir

{"title":"Wear, creep, and frictional heating of femoral implant articulating surfaces and the effect on long-term performance--Part II, Friction, heating, and torque.","authors":"J A Davidson, G Schwartz, G Lynch, S Gir","doi":"","DOIUrl":"","url":null,"abstract":"In Part I, (J.A. Davidson and G. Schwartz, \"Wear, creep, and frictional heating of femoral implant articulating surfaces and the effect on long-term performance--Part I, A review,\" J. Biomed. Mater. Res., 21, 000-000 (1987) it was shown that lubrication of the artificial hip joint was complex and that long-term performance is governed by the combined wear, creep, and to a lesser extent, oxidation degradation of the articulating materials. Importantly, it was shown that a tendency for heating exists during articulation in the hip joint and that elevated temperatures can increase the wear, creep, and oxidation degradation rate of UHMWPE. The present study was performed to examine closely the propensity to generate heat during articulation in a hip joint simulator. The systems investigated were polished Co-Cr-Mo alloy articulating against UHMWPE, polished alumina ceramic against UHMWPE, and polished alumina against itself. Frictional torque was also evaluated for each system at various levels of applied loads. A walking load history was used in both the frictional heating and torque tests. The majority of tests were performed with 5 mL of water lubricant. However, the effect of various concentrations of hyaluronic acid was also evaluated. Results showed frictional heating to occur in all three systems, reaching an equilibrium after roughly 30 min articulation time. Ceramic systems showed reduced levels of heating compared to the cobalt alloy-UHMWPE system. The level of frictional torque for each system ranked similar to their respective tendencies to generate heat. Hyaluronic acid had little effect, while dry conditions and the presence of small quantities of bone cement powder in water lubricant significantly increased frictional torque.","PeriodicalId":15159,"journal":{"name":"Journal of biomedical materials research","volume":"22 A1 Suppl","pages":"69-91"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14498140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomaterial-associated calcification: pathology, mechanisms, and strategies for prevention. 生物材料相关钙化:病理、机制和预防策略。

Journal of biomedical materials research Pub Date : 1988-04-01

F J Schoen, H Harasaki, K M Kim, H C Anderson, R J Levy

{"title":"Biomaterial-associated calcification: pathology, mechanisms, and strategies for prevention.","authors":"F J Schoen, H Harasaki, K M Kim, H C Anderson, R J Levy","doi":"","DOIUrl":"","url":null,"abstract":"Deposition of calcium-containing apatite mineral occurs widely in association with cardiovascular and noncardiovascular medical devices and biomaterials, is the leading cause of failure of contemporary bioprosthetic heart valves, and limits the functional lifetime of experimental (and potentially clinical) mechanical blood pumps and polymeric heart valves. Calcification of bioprosthetic tissue is primarily intrinsic, related to cuspal connective tissue cells and fragments, and collagen. In contrast, the predominant site of calcific crystals on flexing polymeric surfaces in blood pumps or valve prostheses is extrinsic, associated with adherent cells, thrombus, or pseudointima. Pathologic calcification shares key features with physiologic skeletal mineralization, including crystal initiation through the mediation of cell membranes, usually in the form of extracellular vesicles. This suggests a unified hypothesis for normal and abnormal mineralization. Several approaches are being studied experimentally for the inhibition of bioprosthetic heart valve calcification. Controlled-release diphosphonate therapy, perhaps in conjunction with an anticalcification cuspal pretreatment, appears most effective. Research objectives in biomaterial-associated calcification include (1) development of animal models, (2) determination of initial crystal nucleation events and sites, (3) elucidation of the relative roles of host, implant, and mechanical determinants, and (4) development of approaches for the inhibition of mineralization.","PeriodicalId":15159,"journal":{"name":"Journal of biomedical materials research","volume":"22 A1 Suppl","pages":"11-36"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14413040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The combined anterior cruciate and medial collateral ligament replacement by various materials: a comparative animal study. 不同材料联合前交叉韧带和内侧副韧带置换:一项比较动物研究。