Journal of biomedical materials research最新文献_第5页

Applied biomaterials. Proceedings of a symposium on retrieval and analysis of surgical implants and biomaterials. August, 1988. Snowbird, Utah. 应用生物材料。外科植入物和生物材料检索与分析研讨会论文集。1988年8月。雪鸟,犹他州。

Journal of biomedical materials research Pub Date : 1989-12-01

引用次数: 0

An investigation of Bioglass powders: quality assurance test procedure and test criteria. 生物玻璃粉末的研究:质量保证测试程序和测试标准。

Journal of biomedical materials research Pub Date : 1989-08-01

L D Warren, A E Clark, L L Hench

引用次数: 0

Elastic properties and strength of a novel small-diameter, compliant polyurethane vascular graft. 一种新型小直径柔性聚氨酯血管移植物的弹性性能和强度。

Journal of biomedical materials research Pub Date : 1989-08-01

K Hayashi, K Takamizawa, T Saito, K Kira, K Hiramatsu, K Kondo

引用次数: 0

A chronic intracortical electrode array: preliminary results. 慢性皮质内电极阵列:初步结果。

Journal of biomedical materials research Pub Date : 1989-08-01

P K Campbell, R A Normann, K W Horch, S S Stensaas

{"title":"A chronic intracortical electrode array: preliminary results.","authors":"P K Campbell, R A Normann, K W Horch, S S Stensaas","doi":"","DOIUrl":"","url":null,"abstract":"Two sets of electrode arrays made of either 25- or 50-microns-diameter Teflon-insulated platinum-iridium wire and Teflon have been developed for chronic intracortical electrical stimulation. Cortical histological studies were performed following acute and chronic implantation in cats. While some neural damage resulted from the implantations of either array configuration, a unique set of problems was associated with each diameter wire. Arrays with 50-microns electrodes and lead wires tended to maintain interelectrode spacing upon implantation, but the percutaneous leads retained residual stress which made array implantation difficult. Arrays with 25-microns electrodes and lead wires suffered from changes in interelectrode spacing upon implantation, but were much easier to manipulate during surgery. Both array configurations demonstrated some movement after implantation. It is concluded that a chronic intracortical stimulating electrode array of this geometry should have the following properties: 1) the penetrating electrodes and supporting substrate must be stiff (to maintain interelectrode spacings upon implantation), and 2) the percutaneous leads must be extremely flexible (to avoid array movement after implantation).","PeriodicalId":15159,"journal":{"name":"Journal of biomedical materials research","volume":"23 A2 Suppl","pages":"245-59"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13816642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of blood compatibility of PEO grafted and heparin immobilized polyurethanes. PEO移植物和肝素固定化聚氨酯的血液相容性评价。

Journal of biomedical materials research Pub Date : 1989-08-01

D K Han, S Y Jeong, Y H Kim

引用次数: 0

Fatigue properties of acrylic bone cement: S-N, P-N, and P-S-N data. 丙烯酸骨水泥的疲劳性能:S-N, P-N和P-S-N数据。

Journal of biomedical materials research Pub Date : 1989-08-01

J P Davies, T P Harrigan

引用次数: 0

Bone bonding behavior of bead-coated alumina ceramic under load-bearing conditions. 承载条件下珠膜氧化铝陶瓷的骨结合行为。

Journal of biomedical materials research Pub Date : 1989-08-01

H Takagi, T Yamamuro, K Hyakuna, T Nakamura, Y Kotoura, M Oka

{"title":"Bone bonding behavior of bead-coated alumina ceramic under load-bearing conditions.","authors":"H Takagi, T Yamamuro, K Hyakuna, T Nakamura, Y Kotoura, M Oka","doi":"","DOIUrl":"","url":null,"abstract":"Alumina ceramic has good biocompatibility, high mechanical strength, and excellent lubrication properties. However, it is bioinert and does not bond with bone tissue. Therefore, to promote mechanical bonding, we have developed an alumina ceramic material coated with alumina ceramic beads using identical alumina ceramic binder. In this study, we evaluated the bone bonding capability of this material under load-bearing conditions along with its mechanical properties. The test pieces with or without bead-coating were implanted into the load-bearing portions of the medial and lateral femoral condyles of adult mongrel dogs. The dogs were euthanized 4, 8, and 24 weeks after implantation, and the pull-out test and histological examination were performed. The uncoated implants showed signs of loosening similar to those observed clinically. In contrast, the bonding strength of the bead-coated implants was significantly greater than that of the uncoated implants and increased with implantation time. This increase in strength differs from the results obtained in the non-load-bearing experiments, in which a plateau was seen relatively early after implantation. Results of histological examination suggested that this increase was caused by thickening of ingrown trabeculae, which could be observed as early as 4 weeks after implantation, at the bone-implant interface. In addition, the mechanical properties of the bead-coated alumina ceramic were comparable to those of grooved alumina ceramic which has been used clinically. These results indicate the possibility for clinical application of the bead-coated alumina ceramic.","PeriodicalId":15159,"journal":{"name":"Journal of biomedical materials research","volume":"23 A2 Suppl","pages":"161-81"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13816639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone attachment to hydroxyapatite coated polymers. 骨附着羟基磷灰石涂层聚合物。

Journal of biomedical materials research Pub Date : 1989-08-01

P S Boone, M C Zimmerman, E Gutteling, C K Lee, J R Parsons, N Langrana

{"title":"Bone attachment to hydroxyapatite coated polymers.","authors":"P S Boone, M C Zimmerman, E Gutteling, C K Lee, J R Parsons, N Langrana","doi":"","DOIUrl":"","url":null,"abstract":"Bone attachment to two classes of hydroxyapatite (HA) coated polymers was evaluated mechanically and histologically. Particulate HA was molded into the surface of thermoplastic implants and cast into the surface of thermoset implants. Coated and uncoated implants of both types were implanted in the distal femurs of rabbits for four and twelve weeks. After sacrifice, the bone/implant interface was evaluated mechanically via a push-out test with a servohydraulic test system. Paired statistical analysis revealed significantly greater shear strengths for coated vs. uncoated implants for both polymer systems at both time periods. Mixed mode of failure occurred with particle removal from the polymer surface and from the bone. One animal at each time period was saved for histology. Histology at both time periods indicated direct bone apposition to the HA coating as compared to a fibrous encapsulation about the uncoated implants. This was confirmed with backscatter scanning electron microscopy and scanning acoustic microscopy. Hydroxyapatite coatings significantly improve the bond strength between polymers and bone by allowing direct bone apposition and some mechanical interlocking with the bone.","PeriodicalId":15159,"journal":{"name":"Journal of biomedical materials research","volume":"23 A2 Suppl","pages":"183-99"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13816640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deconvoluted X-ray diffraction analysis of bone and mixtures of bone and particulate hydroxyapatite. 骨及骨与羟基磷灰石颗粒混合物的反卷积x射线衍射分析。

Journal of biomedical materials research Pub Date : 1988-04-01

M Germine, J R Parsons

{"title":"Deconvoluted X-ray diffraction analysis of bone and mixtures of bone and particulate hydroxyapatite.","authors":"M Germine, J R Parsons","doi":"","DOIUrl":"","url":null,"abstract":"Recent evidence suggests that bone phosphate exists almost entirely as hydroxyapatite (HA). The relative deficiency of calcium and presence of substantial HPO2-4 in bone phosphate indicates modification of the ideal HA structure, however. An inability to resolve closely spaced lines in fine grained materials, coupled with the limited periodicity of the thin mineral crystals of bone have prevented definitive characterization of the structure of bone mineral using standard X-ray diffraction (XRD) techniques. We have applied computer deconvolution XRD techniques to aid in the resolution of component overlapped profiles from bone, synthetic hydroxyapatite (HA) and mixtures of bone and synthetic HA resulting from implantation studies. In the course of this resolution process separate profiles were resolved from the (002) profile of bone derived HA. The ratio of integrated intensities of these profiles to the intensity of the profile of synthetic HA appears to provide an approximate measure of the ratio of bone to synthetic HA in a given sample. The finding of shoulders on the (002) peak of bone provides the basis for resolution into separate profiles. The asymmetry of these shoulders in mature bone cannot be attributed to crystallinity, particle size, or computer artifact. The same finding has been previously reported in hydrolyzed, deproteinated bone. Further work will be needed to resolve the question of whether the structural heterogeneity implied by profile geometry is the result of multiple HA phases, surface layer structure involving hydrolysis and calcium absences, or some other factor.","PeriodicalId":15159,"journal":{"name":"Journal of biomedical materials research","volume":"22 A1 Suppl","pages":"55-67"},"PeriodicalIF":0.0,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14498139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulation of orthopedic devices. 规管矫形器材。

Journal of biomedical materials research Pub Date : 1988-04-01

引用次数: 0