Journal of Babol University of Medical Sciences最新文献_第10页

بهینه سازی فرآیند اکسیداسیون پیشرفته بر پایه پرسولفات (UV/Na2S2O8/Fe2+) برای حذف فتالیک اسید از محلولهای آبی توسط روش سطح پاسخ

Journal of Babol University of Medical Sciences Pub Date : 2018-02-15 DOI: 10.18869/ACADPUB.JBUMS.20.2.13

مجتبی یگانه بادی, سودا فلاح جوکندان, علی اسرافیلی, سمیرا یوسف زاده, احسان احمدی, علی محسن پور آذری, سید احمد مختاری, سلیمه رضایی نیا, میترا غلامی

引用次数: 1

Production of recombinant CAMP – Sialidase protein and preparation of chitosan nanoparticles carrying this protein to be used as a candidate for vaccines targeting Propionibacterium acnes 重组CAMP -唾液酸酶蛋白的制备及壳聚糖纳米颗粒的制备及其在痤疮丙酸杆菌疫苗中的应用

Journal of Babol University of Medical Sciences Pub Date : 2018-02-10 DOI: 10.18869/ACADPUB.JBUMS.20.2.64

P. Zargham, M. Heshmati, K. Mansouri, J. Amani, J. Salimian, A. Ahmadi

引用次数: 2

The Study of Abnormal Liver Ultrasound Findings in Candidate Patients Undergoing Renal Transplantation from Brain Dead Donors 脑死亡供体肾移植候选患者肝脏超声异常表现的研究

Journal of Babol University of Medical Sciences Pub Date : 2018-02-10 DOI: 10.18869/ACADPUB.JBUMS.20.2.22

M. Sadeghi, M. Aliakbarian, Shaghayegh Beshtar, N. Samiee, E. Khaleghi

{"title":"The Study of Abnormal Liver Ultrasound Findings in Candidate Patients Undergoing Renal Transplantation from Brain Dead Donors","authors":"M. Sadeghi, M. Aliakbarian, Shaghayegh Beshtar, N. Samiee, E. Khaleghi","doi":"10.18869/ACADPUB.JBUMS.20.2.22","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.2.22","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Chronic kidney disease in addition to kidney involvement may cause abnormalities in various systems of the body, in which liver disorders are one of the most commonly encountered disorders. Failure to identify some of these disorders can cause a serious problem in transolant patient. This study was performed to determine the frequency and type of abnormal liver ultrasound findings in renal transplant patients. METHODS: In this cross-sectional study, recorded data of 480 kidney failure patients who had received kidney transplant from brain death donors during the last 6 years in three Mashhad hospitals were investigated. Ultrasonography was considered before the transplant and abnormal liver findings were recorded in a checklist and were assesed. FINDINGS: The mean age was 39.07±12.67 years of which 52.70% were male and 42.30% were female. Liver disorders were observed in 13.12% of patients. The highest prevalence was related to fatty liver grade I (2.5%), grade II (1.46%), gallstone (1.25%) and liver cysts (1.25%). CONCLUSION: The results of the study showed that liver asymptomatic disorders in renal transplant patients have significant prevalence and because some of these disorders require treatment before transplantation, enough attention to screening before transplantation can help to prevent post-transplant complications.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"64 1","pages":"22-26"},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91361824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparison of the Effect of Ondansetron and Propofol on Intrathecal Opioid-Induced itch in Elective Cesarean Section 昂丹司琼与异丙酚对选择性剖宫产术鞘内阿片瘙痒的影响比较

Journal of Babol University of Medical Sciences Pub Date : 2018-02-10 DOI: 10.18869/ACADPUB.JBUMS.20.2.7

A. Mahouri, S. Sane, E. Hassani, H. Rezaie, L. Aghasi

{"title":"A Comparison of the Effect of Ondansetron and Propofol on Intrathecal Opioid-Induced itch in Elective Cesarean Section","authors":"A. Mahouri, S. Sane, E. Hassani, H. Rezaie, L. Aghasi","doi":"10.18869/ACADPUB.JBUMS.20.2.7","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.2.7","url":null,"abstract":"J Babol Univ Med Sci; 20(2); Feb 2018; PP: 7-12 Received: Jun 12 2017, Revised: Sep 23 2017, Accepted: Dec 2 2017. ABSTRACT BACKGROUND AND OBJECTIVE: Itch is one of the most common and uncomfortable side effects of neuraxial anesthesia. Its incidence is higher especially in cesarean section. The aim of this study was to compare the effect of ondansetron and propofol at doses lower than the hypnotic dose on the treatment of itch induced by intrathecal fentanyl in cesarean section. METHODS: In this prospective study, 90 patients with American Society of Anesthesiologists (ASA) class I and class II with an average age of 30 years and first time cesarean section underwent intra-spinal anesthesia with 25 μg fentanyl and 10 mg bupivacaine 0.5%. Women were randomly divided into two groups of 45. One group received 4 mg ondansetron and another group received 10 mg propofol at first and then 10 μg/kg / min through infusion. The incidence and severity of itch were recorded on the basis of the visual scoring system during operation and during recovery. FINDINGS:The highest incidence of itch was 30 to 60 minutes after injection. The incidence of itch during surgery was 2.22% and 7.26%, and during recovery was 7.6% and 8.8%, in the ondansetron and propofol groups, respectively (p=0.5, p=0.4). The mean itch severity scores during surgery were 1.85±0.69 and 1.66±0.81, and during the recovery were 1.33±0.57 and 1.25±0.5, in the ondansetron and propofol groups, respectively (p=0.65) (p=0.84). CONCLUSION: Based on the results of this study, ondansetron and propofol at doses lower than the hypnotic dose were well tolerated. Considering the effect of both drugs on the treatment of itch caused by intrathecal fentanyl, both of them can be used clinically.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"101 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89554782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Iron Oxide Nanoparticles and Magnetic Field on Apoptosis and Bax Gene Expression in Rat Hippocampus after Ischemic Reperfusion 氧化铁纳米颗粒和磁场对大鼠缺血再灌注后海马细胞凋亡和Bax基因表达的影响

Journal of Babol University of Medical Sciences Pub Date : 2018-02-10 DOI: 10.18869/ACADPUB.JBUMS.20.2.42

Sh Bagheri Tari, Z. K. Koohpar, M. Falahati

{"title":"The Role of Iron Oxide Nanoparticles and Magnetic Field on Apoptosis and Bax Gene Expression in Rat Hippocampus after Ischemic Reperfusion","authors":"Sh Bagheri Tari, Z. K. Koohpar, M. Falahati","doi":"10.18869/ACADPUB.JBUMS.20.2.42","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.2.42","url":null,"abstract":"J Babol Univ Med Sci; 20(2); Feb 2018; PP: 42-8 Received: Jan 7 2017, Revised: Oct 22 2017, Accepted: Dec 12 2017. ABSTRACT BACKGROUND AND OBJECTIVE: Stroke is the second leading cause of mortality in the worldwide. After a stroke, many neurons in the ischemic penumbra will undergo apoptosis. The aim of this study was investigation of effects of iron oxide nanoparticles and magnetic field on apoptosis reduction after ischemic reperfusion in rat model. METHODS: In this experimental study, 50 male Wistar rats weighing 220-250g were randomly divided into five groups of 10 rats each: including control, sham (ischemic reperfusion model), ischemic reperfusion+iron oxide nanoparticles (10mg/kg), ischemic reperfusion +magnetic field (1 Tesla, 20 min in 4 days), and ischemic reperfusion+iron oxide nanoparticles and magnetic field groups. Injections were performed intraperitoneally. After Four days, the hippocampi were removed for studying of Apoptosis Induction (by TUNEL technique) and changes in Bax gene expression (by Q-PCR method). FINDINGS: After induction of ischemic reperfusion, TUNEL+ cells number treated with iron oxide nanoparticles (7±2) and or the magnetic field (12±2) had significant decrease (p<0.01) relative to ischemic reperfusion group (27±5) during 4 days. But simultaneous treatment with nanoparticles and magnetic field (23±2.6) did not show significant difference compared to ischemic reperfusion group (27±5) during 4 days. Furthermore Bax gene expression decreased in iron oxide nanoparticles treated group (2.46±0.22) or the magnetic field exposed group (3.28±0.33) significantly (p<0.01)compared to ischemic reperfusion model (5.21±0.73).. CONCLUSION: It seems that iron oxide nanoparticles as well as magnetic field to be two effective methods in decrease of apoptosis after ischemic reperfusion.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"16 1","pages":"42-48"},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89057167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Relationship between Severity of Nasal Septum Deviation and Pneumatization of Mastoid Cells and Chronic Otitis Media 鼻中隔偏曲程度与乳突细胞气化与慢性中耳炎的关系

Journal of Babol University of Medical Sciences Pub Date : 2018-02-10 DOI: 10.18869/ACADPUB.JBUMS.20.2.27

E. Shobeiri, M. Salehi, A. Jalalvandian

{"title":"Relationship between Severity of Nasal Septum Deviation and Pneumatization of Mastoid Cells and Chronic Otitis Media","authors":"E. Shobeiri, M. Salehi, A. Jalalvandian","doi":"10.18869/ACADPUB.JBUMS.20.2.27","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.2.27","url":null,"abstract":"J Babol Univ Med Sci; 20(2); Feb 2018; PP: 27-32 Received: Oct 15 2017, Revised: Jan 23 2018, Accepted: Mar 3 2018. ABSTRACT BACKGROUND AND OBJECTIVE: Nasal septum deviation (NSD) is one of the leading causes of chronic otitis media and pneumatization of mastoid air cells. In this study, the effect of NSD on pneumatization of mastoid cells and the relationship between NSD and chronic otitis media were investigated using CT scan. METHODS: In this cross-sectional study, 75 paranasal sinus CT scans with NSD and mastoid view were investigated. Patients were divided into three groups based on the severity of NSD: mild (deviation less than 9 degrees, 25 patients), moderate (deviation from 9 to 15 degrees, 25 patients) and severe (deviation equal to or greater than 15 degrees, 25 patients). Chronic otitis media is defined as the presence of bone destruction or sclerosis accompanied by mass fluid or structural changes in temporal bone air cells. The pneumatization of mastoid cells was determined visually and as formation of mastoid air cells. FINDINGS: There was no significant difference in the frequency of pneumatization of mastoid cells between mild (25 patients, 100%), moderate (25 patients, 100%) and severe (23 patients, 92%) nasal septum deviation (p = 0.128). However, the prevalence of chronic otitis media was significantly higher in severe NSD (13 patients, 52%) compared to mild (4 patients, 16%) and moderate (9 patients, 36%) NSD (p = 0.028) CONCLUSION: The results of the study showed that the severity of NSD does not have an effect on pneumatization of mastoid cells, but severe NSD increases the frequency of otitis media.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"32 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89585150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

مقایسه کارایی نسبی بیمارستانهای وابسته به علوم پزشکی بابل و مازندران قبل و بعد از طرح تحول سلامت با تکنیک تحلیل پوششی داده ها

Journal of Babol University of Medical Sciences Pub Date : 2018-01-15 DOI: 10.18869/acadpub.jbums.20.1.68

اباذر عموزاده دوغیکلا, رضا شاه وردی, فرزاد رضائی بالف

引用次数: 0

Effect of Ursodeoxycholic Acid on Pentylenetetrazole Kindling and Kindling Induced Memory Impairment in Rat 熊去氧胆酸对戊四唑点火及点火所致大鼠记忆损伤的影响

Journal of Babol University of Medical Sciences Pub Date : 2018-01-15 DOI: 10.18869/ACADPUB.JBUMS.20.1.56

مریم نادری, ابوالفضل ژند, یحیی ژند, تینا رهجو, محمدرضا پالیزوان

{"title":"Effect of Ursodeoxycholic Acid on Pentylenetetrazole Kindling and Kindling Induced Memory Impairment in Rat","authors":"مریم نادری, ابوالفضل ژند, یحیی ژند, تینا رهجو, محمدرضا پالیزوان","doi":"10.18869/ACADPUB.JBUMS.20.1.56","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.1.56","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Epilepsy is one of the common diseases of the brain that about 30-40 of patients with epilepsy experience recurent attacks due to drug resistance. Recently, the beneficial effects of Ursodeoxycholic acid on brain disorders have been considered. The aim of this study was to evaluate the effect of Ursodeoxycholic acid(UDCA)on the Pentylenetetrazole (PTZ) induced kindling, and related learning and memory impairments on Morris water maze. METHODS: This experimental study was done on 32 male Winstar rats divided into 4 groups. The first(n=7)and the second (n=9) groups have received three injections of 0.5 ml NaCl or 50 mg/kg of UDCA respectively and third(n=7) and fourth(n=9) groups have received fifteen injections of 0.5 ml NaCl or 50 mg/kg of UDCA respectively. All injections were given intraperitoneally(ip)(every 48 hours). In all groups, chemical kindling were started after third injections. Twenty-four hour after the last injection, spatial memory was investigated in the Morris water maze. FINDING: Fifteen injections of UDCA significantly reduced the seizure stage from 3.5±0.17 to 3.08±0.11 and duration of stages five from 12.38±1.2 to 8.61±0.58 and increased time to reach the stage five seizures from 1021.65±72.07 to 1252.41±49.63 as compared to control group. However, three injections of UDCA have no effect on the kindling process. However, three time administration of UDCA significantly increased reference memory from 18.72±1.2 s to 26.11±1.8 s. CONCLUSION: Ursodeoxycholic acid inhibits chemical kindling and improves kindling induced memory impairment. © 2018, Babol University of Medical Sciences. All rights reserved.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"831 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73665451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

اثربخشی آب، شیر و آب لیموی طبیعی درترشح کبدی-صفراوی رادیوداروی99mTc-MIBI دراسکن پرفیوژن قلب

Journal of Babol University of Medical Sciences Pub Date : 2018-01-10 DOI: 10.18869/acadpub.jbums.20.1.12

سید حسین موسوی انیجدان, امیر غلامی

引用次数: 1

A Case Report of Asymptomatic Glandular Odontogenic Cyst Mimicking as a Nasopalatine Duct Cyst 无症状腺源性牙源性囊肿酷似鼻腭管囊肿1例

Journal of Babol University of Medical Sciences Pub Date : 2018-01-10 DOI: 10.18869/acadpub.jbums.20.1.7

S. Nafarzadeh, A. Pournabi, F. Bijani

引用次数: 0