{"title":"Current State of Genome Medicine in the World","authors":"Yasushi Okazaki","doi":"10.7143/jhep.49.271","DOIUrl":"https://doi.org/10.7143/jhep.49.271","url":null,"abstract":"","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115019678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gene-related Examination in Health Evaluation and Promotion","authors":"T. Yamagami","doi":"10.7143/jhep.49.255","DOIUrl":"https://doi.org/10.7143/jhep.49.255","url":null,"abstract":"This paper describes the present state and problems of genetic testing of monogenic and multifactorial disorders in genetic disorder. Hereditary breast and ovarian cancer syndrome (HBOC) is picked up as a sample of monogenic disorder. Persons affected by HBOC have mutations in BRCA1/BRCA2 gene, therefore, persons who have mutations in those genes must be taken care of occurrence of HBOC. Persons who have the plural number of family history about breast or ovarian cancers had better recommended to genetic testing of BRCA1/2 gene. Genome-wide association study (GWAS) and polygenic risk factor (PRS) study are developed rapidly but those studies about Japanese population are few for the present. Many genetic disorders are specific to populations. GWAS or PRS using Japanese population must increase from now on. genome-wide association study polygenic","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128729719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Informed-consent and Result Explanation of Genomic Testing","authors":"N. Yamashita","doi":"10.7143/jhep.49.278","DOIUrl":"https://doi.org/10.7143/jhep.49.278","url":null,"abstract":"Genomic testing is now becoming popular. Although DTC (direct-to-consumer) service for genomic testing is available through internet, some problems remain in DTC. My co-investigators and I have investigated the efficacy of genomic testing, and found that it was useful if the results were properly explained by the doctor. In this study we prepared the informed consent form and developed the method for explanation, which I describe in this article. Various items including the purpose, significance and methods for genomic testing, and the way to protect personal information should be included in the informed consent form. With regard to explanation of the results, data of health check and information of family history are also taken into account and the explanation should be done by the doctor in person. When the rare variant is detected, the examinee is introduced to the genetic counselor and the specialist prior to the explanation of common variants. When rare variants are not detected, explanation of common variants, which includes diseases, diathesis and drug responses, is carried out. Disease risk consists of genetic and environmental risk. It is important to educate that overall disease risk is reduced by decreasing the environmental risk, which can be achieved by the examinee’s own effort to improve the life style.","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"151 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126115696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of the Feasibility of Implementing Nutrition Education for Health Promotion at the Company Cafeteria: Attempt to Provide Information of Nutrition Education to the Company Cafeteria Management Staffs","authors":"J. Murata, Yukiko Yoshioka","doi":"10.7143/jhep.49.289","DOIUrl":"https://doi.org/10.7143/jhep.49.289","url":null,"abstract":"Objective: To study the feasibility of implementing nutrition education for health promotion at the company cafeteria by providing information of nutrition education to the company cafeteria management staffs. Methods: In order to examined changes in knowledge and attitude (intention and self-efficacy) of the contents of the nutrition education for health promotion at the company cafeteria, self-administered questionnaire survey to four company cafeteria management staffs and one employee of the company cafeteria were conducted. For the survey, the nutrition education manual for health promotion at the company cafeteria was prepared in advance based on the actual situation of the company cafeteria, and provided to the targets at the time of the survey. This study was a case series study based on the KAP-KAB model, the Theory of Planned Behavior, and the concepts of self-efficacy and intention. Results: After reading the manual, the answers of all the company cafeteria management staffs were almost positive that they understood the contents related to nutrition education for health promotion at the company cafeteria and they would like to implement to provide nutrition education for health promotion. However, in terms of self-efficacy, there the answers were given both high and low, showing differences depending on the nutrition education. On the other hand, the answer of the cafeteria employee in relation to intention appeared almost positive but it depends whether the company cafeteria management staffs understood nutrition education or not. Conclusions: Providing information of nutrition education to the company cafeteria management staffs improved their knowledge and attitudes, the survey demonstrates the feasibility of implementing nutrition education for health promotion at the company cafeteria. For collaborative efforts by company cafeteria management staffs and cafeteria employees in implementing nutrition education, it is necessary to review the content of providing information and the behavioral science theories to be used. company health provide","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115237135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Ishii, K. Asahi, R. Yoshida, Katsumi Arai, Yayoi Masuno, Yoko Saito, F. Katsukawa
{"title":"Risk of Elevated Blood Pressure Based on Obesity Criteria: Comparison of Body Mass Index and Waist Circumference","authors":"H. Ishii, K. Asahi, R. Yoshida, Katsumi Arai, Yayoi Masuno, Yoko Saito, F. Katsukawa","doi":"10.7143/jhep.49.308","DOIUrl":"https://doi.org/10.7143/jhep.49.308","url":null,"abstract":"Purpose: This study aims to compare the risk of elevated blood pressure in relation to obesity using three of its criteria, and to determine its association with body mass index (BMI) and waist circumference (WC). Method: This study enrolled 15,560 individuals: 7,126 men and 8,434 women, aged 20–59 years, who had undergone annual workplace health checkups at two adjacent prefectures in the Tohoku region in 2013. Some individuals were flagged because of the following reasons: missing data, use of antihypertensive medication, uncertainty about the use of antihypertensive medication, smoking habit, or clinically implausible values. These individuals were excluded. The participants were classified first by sex and then by age group: those in their 20s and 30s and those in their 40s and 50s. Four cutoff values for blood pressure (sBP/dBP: ≧ 120/80, ≧ 130/80, ≧ 130/85, and ≧ 140/90 mmHg) were compared using three obesity criteria (BMI and criteria by the Japan Society for the Study of Obesity and the World Health Organization for WC ). The areas under the receiver operating characteristic (ROC) curves (AUCs) for BMI and WC for each cutoff value were compared using the DeLong test, and further cutoff values were calculated. Results: The odds ratios for participants in their 20s and 30s (men: 3.78–6.75, women: 3.80– 8.37) were greater than those for participants in their 40s and 50s (men: 1.87–2.64, women: 2.41–4.15). Comparisons of BMI and WC by AUC of the ROC curve did not show significant differences for most criteria, except for women in their 40–50s and ≧ 120/80 mmHg. Conclusion: Our results showed no significant difference between BMI and WC in determining elevated blood pressure. In addition, for many criteria, AUC<0.7 was a limitation in predicting high blood pressure using obesity indices alone.","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117264944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Supporting Changes in Physical Activity Due to Covid-19","authors":"Kumi Watanabe","doi":"10.7143/jhep.49.324","DOIUrl":"https://doi.org/10.7143/jhep.49.324","url":null,"abstract":"the declaration of a state of emergency in response to the Covid-19 pandemic, the lifestyles physical activity immunity, to","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125423949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Establishment of Standard Image Finding Names, Synonyms, and Location Names for Glossary of Health Checkup Terms","authors":"Nobuyuki Kobayashi","doi":"10.7143/jhep.48.511","DOIUrl":"https://doi.org/10.7143/jhep.48.511","url":null,"abstract":"","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129014445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation Between Anthropometric Measurements and Radiation Doses by X-ray Examination of the Upper Gastrointestinal Tract","authors":"M. Nemoto, Y. Inaba, Yuya Kumada, K. Chida","doi":"10.7143/jhep.48.495","DOIUrl":"https://doi.org/10.7143/jhep.48.495","url":null,"abstract":"The upper gastrointestinal tract (UGI) is useful in gastric cancer screening, but it has the disadvantage of exposure due to radiographic examinations under fluoroscopy. The purpose of this study was to compare the median value of radiation dose for UGI in a medical clinic and Diagnostic Reference Levels 2020 (DRLs2020). We also estimated the correlation between radiation dose and four anthropometric measurements (height, weight, Body Mass Index, and abdominal girth). The median value of air kerma-area product (P KA ) and incident air kerma at the patient entrance reference point (K a,r ) were 17.0 Gycm 2 and 64.9 mGy respectively, that were about 0.6 to 0.7 times higher than DRLs2020. The median value of the fluoroscopic time was 168.4 seconds. There was a strong correlation between radiation dose for UGI and the body weight, BMI, and abdominal girth (R=0.71). The relationship between anthropometric measurements and radiation dose for UGI was strongly influenced by fluoroscopic doses which accounts for 83% of the total dose and fluoroscopic times.","PeriodicalId":150891,"journal":{"name":"Health Evaluation and Promotion","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129831006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}