{"title":"PRODUCT FOCUS: Analytical and Preparative Instrumentation","authors":"","doi":"10.1177/10870571070120071301","DOIUrl":"https://doi.org/10.1177/10870571070120071301","url":null,"abstract":"profiling (RAP) technology, RAP id 4 enables real-time, label-free measurement and analysis of biomolecular interactions. RAP measures the oscillation of a resonating quartz crystal, which decreases in proportion to the mass of the molecules binding to its surface. Proprietary electronics and algorithms generate measurements, which provide binding information on biomolecular interactions. RAP measures materials that physically bind to the crystal and is unaffected by solvents. Researchers interrogate and evaluate the data using RAP id workbench software. The system is flow based and generates kinetic, affinity, and concentration measurements from mixtures such as cell culture supernatants and periplasmic extracts. A stand-alone automated platform, RAP id 4 typically processes an average of 400 samples per day. For further information, visit www.akubio.com.","PeriodicalId":15087,"journal":{"name":"Journal of Biomolecular Screening","volume":"12 1","pages":"1012 - 1018"},"PeriodicalIF":0.0,"publicationDate":"2007-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/10870571070120071301","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65310370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Product Focus","authors":"","doi":"10.1177/10870571070120051601","DOIUrl":"https://doi.org/10.1177/10870571070120051601","url":null,"abstract":"BioTek Instruments has announced the SynergyTM 2 Multi-Detection Microplate Reader, which is a 5-mode microplate reader. Detection modes include fluorescence intensity, fluorescence polarization, time-resolved fluorescence, luminescence, and UV-visible absorbance. The reader uses a combination of monochromator, filters and dichroic mirrors, and 3 broad-spectrum light sources. It is driven by BioTek Instruments’ Gen5TM Reader Control and Data Analysis","PeriodicalId":15087,"journal":{"name":"Journal of Biomolecular Screening","volume":"12 1","pages":"748 - 752"},"PeriodicalIF":0.0,"publicationDate":"2007-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/10870571070120051601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65310358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Product Focus","authors":"Assay ReagentsSupplies","doi":"10.1177/108705710501000111","DOIUrl":"https://doi.org/10.1177/108705710501000111","url":null,"abstract":"division. This antibody is targeted against human cyclophilin A, which is thought to play an important role in the mechanism of protein folding. Non-animal-based and in vitro–generated recombinant antibodies are new to the research markets and seem to have several advantages over traditional antibodies. They can be generated within 8 weeks from only a minimum amount of protein, DNA, or peptide. In addition, in vitro–generated antibodies allow for high-throughput production, thus facilitating the development of novel array platforms.","PeriodicalId":15087,"journal":{"name":"Journal of Biomolecular Screening","volume":"10 1","pages":"80 - 84"},"PeriodicalIF":0.0,"publicationDate":"2005-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/108705710501000111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65309304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Product Focus","authors":"","doi":"10.1177/1087057104272442","DOIUrl":"https://doi.org/10.1177/1087057104272442","url":null,"abstract":"and cosmids kept in almost all known media types. Robots perform a series of plate and tube actions that transfer compounds from their original source plate locations to desired destination plate locations for particular screens, providing up to 20,000 picks per day. Housed in a cold-room environment, the MatriStore system operates at –20 °C, with storage capacity from 750,000 to 40 million compounds. Orders are submitted and the status of pending requests verified through an intuitive graphical user interface.","PeriodicalId":15087,"journal":{"name":"Journal of Biomolecular Screening","volume":"9 1","pages":"737 - 740"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1087057104272442","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65306656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From the Desk of the SBS Executive Director.","authors":"C. Giordano","doi":"10.1089/108705701753364850","DOIUrl":"https://doi.org/10.1089/108705701753364850","url":null,"abstract":"","PeriodicalId":15087,"journal":{"name":"Journal of Biomolecular Screening","volume":"6 6 1","pages":"363-4"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60621120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Male caregivers of spouses with Alzheimer's disease: risk factors and health status.","authors":"H A Shanks-McElroy, J Strobino","doi":"10.1177/153331750101600308","DOIUrl":"10.1177/153331750101600308","url":null,"abstract":"<p><p>Caregiving for persons with Alzheimer's disease (AD) has been shown to pose a challenge to the health of the spousal caregiver. Because most of the caregiving literature focuses on the female caregiver, there is some question about the generalizability of such literature to the male caregiver. This report focuses on male caregivers of spouses with AD and represents a subsample from a larger descriptive study that examined the relationship between risk factors and the health status of spousal caregivers. Twenty-nine male caregivers affiliated with Alzheimer's organizations in Pennsylvania and Ontario, Canada, returned mail surveys. On average, physical health symptoms increased by one-third when comparing pre- and post-caregiving data. Caregivers also were experiencing moderate to severe depression and burden. Male caregivers generally rated their physical health as fair to excellent and exhibited fewer than expected physical health symptoms. Caregiver health was related to perceptions of stress surrounding the provision of activities of daily living (ADL) assistance, the frequency of behavioral problems, perceptions of stress associated with the AD spouse's dysfunctional behaviors, and satisfaction with leisure opportunities. The identification of the role that caregiver perceptions of stressfulness associated with caregiving and the need for leisure satisfaction offer important implications for community-based education and respite services to maintain health status for spousal caregivers.</p>","PeriodicalId":15087,"journal":{"name":"Journal of Biomolecular Screening","volume":"12 1","pages":"167-75"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10833828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87384563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
