Annals of Clinical Nutrition and Metabolism最新文献

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Letter from the Editor 编辑来信
Annals of Clinical Nutrition and Metabolism Pub Date : 2021-12-31 DOI: 10.15747/acnm.2021.13.2.25
Suk‐Kyung Hong
{"title":"Letter from the Editor","authors":"Suk‐Kyung Hong","doi":"10.15747/acnm.2021.13.2.25","DOIUrl":"https://doi.org/10.15747/acnm.2021.13.2.25","url":null,"abstract":"I applaud my colleagues for undertaking the SIngulair in Mild asthma: comPLiance and Effectiveness (SIMPLE) study (1) because real-world studies are crucial to our understanding of asthma care. Given the trial design and patient characteristics, I believe that their conclusions are misleading. The authors indicate that in the survey phase, 75.9% of patients were not adherent to inhaled corticosteroid (ICS) therapy and, at baseline, 58.1% of patients reported not missing any ICS doses during the previous two weeks. The authors should reconcile these different adherence reports. It is also important to know why the majority of patients in the survey phase did not progress to the treatment phase. If the reason for this discrepancy was related to wellcontrolled asthma, it should be stated and included in the discussion because this would influence how the reader interprets the data from a clinical perspective; if this was the case, then only a minority of patients not well controlled with ICS benefited from montelukast as an alternative therapy. Furthermore, because more than 40% of patients at baseline were not adherent to ICS, it does not appear reasonable that the group – as a whole – should serve as a control, particularly because we do not know if those patients who were compliant were receiving adequate doses of ICS. The latter comments and the lack of ICS and placebo arms make it very difficult – if not impossible – to interpret the results of the SIMPLE study in a clinically meaningful way, although the conclusions suggest that “montelukast is an effective...alternative to ICS treatment in patients with mild asthma who are uncontrolled... with low-dose ICS therapy”. I am troubled by the fact that inappropriate use of ICS is compared with a therapeutic intervention that is not considered first line (2). I do not believe that it is appropriate (given some critical design limitations of the study) to compare real world-driven outcomes measured at baseline with protocol (clinical trial) -driven outcomes given the influence that clinical trial participation may have on patient behaviour. The authors should have clarified what proportion of the survey population receiving ICS failed to make it to treatment because of well-controlled asthma, because this would have conveyed an important and reassuring message to family physicians about the effectiveness of ICS in this population. The theme in the discussion should have focused more on the importance of compliance with ICS, rather than presenting second-line therapy as a therapeutic equivalent.","PeriodicalId":150496,"journal":{"name":"Annals of Clinical Nutrition and Metabolism","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130433412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Significance of Malnutrition Risk in Severe Trauma Patients: A Single-Center Study 严重创伤患者营养不良风险的临床意义:一项单中心研究
Annals of Clinical Nutrition and Metabolism Pub Date : 2021-12-31 DOI: 10.15747/acnm.2021.13.2.68
Hohyun Kim, Ku Hong, I. Choi, K. Lee, G. Song
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引用次数: 0
Perioperative Management of Morbidly Obese Patients during Major Abdominal Surgery 腹部大手术中病态肥胖患者围手术期的处理
Annals of Clinical Nutrition and Metabolism Pub Date : 2021-12-31 DOI: 10.15747/acnm.2021.13.2.26
B. Na, Sang-Jae Park
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引用次数: 0
Clinical Significance of Sarcopenia in Patients with Advanced Hepatocellular Carcinoma Undergoing Sorafenib Treatment 索拉非尼治疗晚期肝癌患者肌肉减少的临床意义
Annals of Clinical Nutrition and Metabolism Pub Date : 2021-12-31 DOI: 10.15747/acnm.2021.13.2.62
Min-Hyuk Lee, Min-Su Park
{"title":"Clinical Significance of Sarcopenia in Patients with Advanced Hepatocellular Carcinoma Undergoing Sorafenib Treatment","authors":"Min-Hyuk Lee, Min-Su Park","doi":"10.15747/acnm.2021.13.2.62","DOIUrl":"https://doi.org/10.15747/acnm.2021.13.2.62","url":null,"abstract":"","PeriodicalId":150496,"journal":{"name":"Annals of Clinical Nutrition and Metabolism","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128058873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Post-Operative Nutritional Status according to the Extent of Gastrectomy and the Reconstruction Method in Patients with Gastric Cancer 胃癌患者术后营养状况与胃切除术及重建方式的比较
Annals of Clinical Nutrition and Metabolism Pub Date : 2021-12-31 DOI: 10.15747/acnm.2021.13.2.34
Kyung Hwan Kim, J. Yoon, G. Song, M. Son, S. Kim, M. Baek, Moon-Soo Lee
{"title":"Comparison of Post-Operative Nutritional Status according to the Extent of Gastrectomy and the Reconstruction Method in Patients with Gastric Cancer","authors":"Kyung Hwan Kim, J. Yoon, G. Song, M. Son, S. Kim, M. Baek, Moon-Soo Lee","doi":"10.15747/acnm.2021.13.2.34","DOIUrl":"https://doi.org/10.15747/acnm.2021.13.2.34","url":null,"abstract":"","PeriodicalId":150496,"journal":{"name":"Annals of Clinical Nutrition and Metabolism","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128987809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal Change in Health-Related Quality of Life after Total Gastrectomy: Approach Based on the Minimally Important Difference 全胃切除术后健康相关生活质量的纵向变化:基于最小重要差异的方法
Annals of Clinical Nutrition and Metabolism Pub Date : 2021-12-31 DOI: 10.15747/acnm.2021.13.2.43
S. Park, O. Jeong, Ji Hoon Kang, M. Jung
{"title":"Longitudinal Change in Health-Related Quality of Life after Total Gastrectomy: Approach Based on the Minimally Important Difference","authors":"S. Park, O. Jeong, Ji Hoon Kang, M. Jung","doi":"10.15747/acnm.2021.13.2.43","DOIUrl":"https://doi.org/10.15747/acnm.2021.13.2.43","url":null,"abstract":"","PeriodicalId":150496,"journal":{"name":"Annals of Clinical Nutrition and Metabolism","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124403279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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