Journal of baghdad college of dentistry最新文献

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Minimally invasive access cavities in endodontics 牙髓学中的微创通道腔
Journal of baghdad college of dentistry Pub Date : 2023-06-15 DOI: 10.26477/jbcd.v35i2.3406
Lubna A Abdulrazaq, A. Ali, F. Foschi
{"title":"Minimally invasive access cavities in endodontics","authors":"Lubna A Abdulrazaq, A. Ali, F. Foschi","doi":"10.26477/jbcd.v35i2.3406","DOIUrl":"https://doi.org/10.26477/jbcd.v35i2.3406","url":null,"abstract":"Background: The access cavity is a critical stage in root canal therapy and it may influence the subsequent steps of the treatment. The new minimally invasive endodontic access cavity preparation concept aims to preserve sound tooth structure by conserving as much intact dentine as possible including the pulp chamber's roof, to keep the teeth from fracturing during and after endodontic treatment. While there is great interest in such access opening designs in numerous publications, still there is a lack of scientific evidence to support the application of such modern access cavity designs in clinical practice. This review aims to critically examine the literature on minimal access cavity preparations, explain the effect of minimally invasive access cavity designs on various aspects of root canal treatment, and identify areas where additional research is required. Data: An electronic search for English-language articles was performed using the following databases: Google Scholar, PubMed, and Research Gate. The following keywords were used: \"minimally invasive access cavity\", \"conservative endodontic cavity \", and \"classification of access cavity\". Study selection: 64 papers that were the most relevant to the topics in this review were selected between 1969 to 26 February 2022. Conclusions: Minimally invasive access cavities can be classified into conservative, ultraconservative, truss access, caries and restorative-driven cavities. There is a deficiency of proof that a minimally invasive access cavity maintains the resistance to fracture of endodontically treated teeth greater than traditional access cavities. There was no difference in the percentage of untouched walls and debris removal in teeth with conservative vs traditional access cavities, however, truss and ultraconservative access cavities resulted in poor irrigation efficacy compared to traditional ones. Also, the lower cyclic fatigue resistance of rotary instruments and root canal obturation with voids were associated with minimally invasive access cavities. The studies about minimally invasive access cavities still have a wide range of methodological disadvantages or register unsatisfactory or inconclusive results. Therefore, further research on this topic is needed especially with the everyday advancement of techniques and armamentarium used in endodontics.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80200893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of titanium dioxide nanoparticles on the activity of salivary peroxidase in periodontitis patients 二氧化钛纳米颗粒对牙周炎患者唾液过氧化物酶活性的影响
Journal of baghdad college of dentistry Pub Date : 2023-06-15 DOI: 10.26477/jbcd.v35i2.3393
Mays A Talib, Basima G Ali, Eaman A Al-Rubaee, Maysaa Mahdy
{"title":"The Effect of titanium dioxide nanoparticles on the activity of salivary peroxidase in periodontitis patients","authors":"Mays A Talib, Basima G Ali, Eaman A Al-Rubaee, Maysaa Mahdy","doi":"10.26477/jbcd.v35i2.3393","DOIUrl":"https://doi.org/10.26477/jbcd.v35i2.3393","url":null,"abstract":"Background:The technology of nanoparticles has been expanded to many aspects of modern life. Titanium dioxide nanoparticles were of many nanomaterials utilized in biomedical applications. The interactions between nanoparticles and proteins are believed to be the base for the biological effect of the nanoparticles. The oxidation reaction of many substances is catalyzed by oxidizing enzymes called peroxidases. The activity of salivary peroxidase is elevated with periodontal diseases. the aim ofthis study is to examine the action of titanium dioxide nanoparticles on salivary peroxidase activity.Material and method75 participants were enrolled in this study—Periodontitis group with 44 participants and the non-periodontitis group with 31 participants. The participants' age range was 35 to 50 years for both groups. The clinical parameters of plaque index, gingival index, probing pocket depth and clinical attachment level were used in this study to determine the presence or absence of the periodontal disease. Unstimulated saliva was collected from all participants and analyzed for the activity of peroxidase enzyme under the effect of titanium dioxide nanoparticles. ResultsThe Periodontitis group showed higher peroxidase enzyme activity than the non-periodontitis group and the activity of salivary peroxidase showed no correlation with the clinical parameters. Titanium dioxide nanoparticles increased salivary peroxidase activity. ConclusionThis study demonstrated that the solid surface of nanoparticles could induce changes in the attached protein molecule which in turn causes changes in the effect of the nanoparticles on living tissue or organism. The titanium dioxide nanoparticles Play a role in increasing the activity of salivary peroxidase within the saliva of chronic periodontitis patients.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84953000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro assessment of bracket adhesion post enamel conditioning with a novel etchant paste 新型蚀刻膏体对牙釉质调理后支架附着力的体外评价
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3309
Hayder A. Kadhim, Sanjukta Deb, Ali I Ibrahim
{"title":"In vitro assessment of bracket adhesion post enamel conditioning with a novel etchant paste","authors":"Hayder A. Kadhim, Sanjukta Deb, Ali I Ibrahim","doi":"10.26477/jbcd.v35i1.3309","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3309","url":null,"abstract":"Background: 37% phosphoric acid (PA) is the traditional enamel etching technique prior to bracket ‎adhesion, yet it has been implicated in numerous enamel injuries. The purpose of the current study was to create a calcium phosphate (CaP) etching paste in a ‎‎simplified capsule ‎formula that can underpin clinically ‎adequate bracket bond strength ‎without jeopardizing the ‎integrity of enamel upon ‎the debracketing procedure. Materials and Methods: micro-sized hydroxyapatite (HA) powder was mixed with 40% PA solution to prepare ‎experimental acidic CaP paste. Sixty human premolars were ‎assigned into two groups of 30 each. ‎Enamel conditioning was accomplished using 37% PA-gel‎ for control group and CaP paste for experimental group. Each group was further divided into two subgroups regarding the water storage (WS) period (24 h and 30 days). Shear bond strength (SBS) test conducted with examination of debonded surfaces for adhesive remnants and enamel damage using a digital microscope. Results: CaP paste produced significantly lower SBS values than PA (p < 0.01), yet sufficient for clinical use. PA etching caused often cracked enamel surfaces with excessive ‎retention of adhesive remnants (mainly ARI scores 2 and 3). Contrarily, enamel treated with the experimental CaP paste exhibited smooth, ‎unblemished surfaces mostly clean of adhesives residues (scores 0 and 1). Conclusion: a newly developed CaP paste in a capsule formula fosters ‎clinically adequate bracket ‎adhesion with a sustained bonding performance, allows a harmless bracket removal with ‎minimal or no adhesive residues on debonded surfaces; thus, it can be introduced as a suitable ‎alternative to PA‎.  ","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72501645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete Blood Count and saliva parameters as an indicator for infected patients with coronavirus covid-19 全血细胞计数和唾液参数作为covid-19感染患者的指标
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3317
Sumaiah I. Hussein, S. Abd, F. A. Al-khayat, Heba k Mahmood
{"title":"Complete Blood Count and saliva parameters as an indicator for infected patients with coronavirus covid-19","authors":"Sumaiah I. Hussein, S. Abd, F. A. Al-khayat, Heba k Mahmood","doi":"10.26477/jbcd.v35i1.3317","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3317","url":null,"abstract":"Background: Coronavirus, which causes respiratory illness, has been a public health issue in recent decades. Because the clinical symptoms of infection are not always specific, it is difficult to expose all suspects to qualitative testing in order to confirm or rule out infection as a test. Methods: According to the scientific studies and investigations, seventy-three results of scientific articles and research  were obtained using PubMed, Medline, Research gate and Google Scholar. The research keywords used were COVID-19, coronavirus, blood parameters, and saliva. Results: This review provides a report on the changes in the blood and saliva tests of those who are infected with the COVID-19.COVID-19 is a systemic infection that has a substantial influence on the hematological system and hemostasis, thus deviations from normal levels of laboratory tests, including the blood and saliva test show that specific testing for detecting COVID-19 infection is required. Conclusions: The blood and saliva tests aid in the clinical monitoring of the patient's health.  It has advantages such as the following: it has non-invasive properties, low cost, and good stability, addition to minimum risk of infection transport.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83947665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crystallization firing effect on the marginal discrepancy of the IPS. emax CAD crowns using two different CAD/CAM systems 结晶烧成效应对IPS边缘差异的影响。emax CAD冠使用两个不同的CAD/CAM系统
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3316
Fatima K Ghadeer, L. E. Alwan, A. K. Al-Azzawi
{"title":"Crystallization firing effect on the marginal discrepancy of the IPS. emax CAD crowns using two different CAD/CAM systems","authors":"Fatima K Ghadeer, L. E. Alwan, A. K. Al-Azzawi","doi":"10.26477/jbcd.v35i1.3316","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3316","url":null,"abstract":"Background: Marginal adaptation is critical for long – term success of crown and bridge restoration. Computer aided design / computer aided manufacture (CAD/ CAM) system is gaining more importance in the fabrication of dental restoration. Objective: The aim of this study is to evaluate the effect of crystallization firing on the vertical marginal gap of IPS. emax CAD crowns which fabricated with two different CAD/CAM systems .Materials and Methods: Twenty IPS e.max CAD crowns were fabricated. We had two major groups (A, B) (10 crowns for each group) according to the CAD/CAM system being used: Group A: fabricated with Imes - Icore CAD/CAM system; Group B: fabricated with In Lab Sirona CAD/CAM system. Each group was subdivided into two subgroups pre-crystallized (Group A1, B1) and crystallized crowns (Group A2, B2). At four points on each aspect of the crown, marginal gaps were assessed on the master metal die by using digital microscope at a magnification of (110X) and image- J program. The measurement was done twice for each crown; before and after crystallization process.Results: The lowest mean of marginal gap before and after crystallization was (29.387±2.774μm) and (70.108±5.569μm) respectively for Group A (Imes - Icore system) and the highest mean value before and after crystallization was (51.728 ±3.774μm) and (84.071 ±4.567μm) respectively for Group B (Sirona system). Paired sample t-test result showed a statistically highly significant difference in marginal gap between all groups.Conclusions: The crystallization process increases the vertical marginal gap. Imes - Icore system showed the lower marginal gap than Sirona system. The two systems have an acceptable marginal gap","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83624070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of adding titanium dioxide nanoparticles on anti-microbial activity and surface detail reproduction of dental alginate 二氧化钛纳米颗粒对藻酸盐抑菌活性及表面细节繁殖的影响
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3313
Ranj A. Omer, Hoshang Kh. Abdel-Rahman, Mahabad Saleh, Sazgar S. Q. AL-Hawezi, Fahd S. Ikram
{"title":"Effect of adding titanium dioxide nanoparticles on anti-microbial activity and surface detail reproduction of dental alginate","authors":"Ranj A. Omer, Hoshang Kh. Abdel-Rahman, Mahabad Saleh, Sazgar S. Q. AL-Hawezi, Fahd S. Ikram","doi":"10.26477/jbcd.v35i1.3313","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3313","url":null,"abstract":"Most dental works require a diagnostic impression; alginate is contemplated as the most popular material used for this purpose. Titanium dioxide nanoparticles show evidence of antimicrobial activity in the recent era, for this purpose, this study aimed to evaluate the effect of adding Titanium dioxide nanoparticles on antimicrobial activity and surface detail reproduction of alginate impression material. Materials and methods: Titanium dioxide nanoparticles (purity = 99%, size= 20nm) was added to alginate at three different concentrations (2%, 3% and 5%). 84 samples were prepared in total. Samples were tested for antimicrobial activity using a disc diffusion test, and surface detail reproduction was done using (ISO 21563:2021). One-way ANOVA and independent sample t-test were used for data analysis through SPSS software. Results: for the antimicrobial test, inhibition zones for Streptococcus mutans and Candida albicans showed significant changes concerning the alteration in Titanium dioxide nanoparticle concentrations. The inhibition zone significantly increased with an increase in the percentage of Titanium dioxide nanoparticles. The mean of the inhibition zone for S. mutans was superior to C. albicans and the difference was statistically significant. Regarding surface detail reproduction, the control group, 2% and 3% groups manifested very similar results, only the group to which 5% of Titanium dioxide nanoparticles were added showed a decline in detail reproduction when compared to the other three groups. Conclusion: Within the limitation of this study, we can conclude that the antimicrobial activity against S mutans and C. albicans were significantly increased in modified groups, and this escalation was directly linked to the increase in Titanium dioxide nanoparticles concentration. In contrast, the surface detail reproduction was decreased when adding 5% Titanium dioxide nanoparticles to alginate.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84076831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of a novel coating material on the microleakage of glass hybrid restoration in primary teeth – An in vitro study 新型涂层材料对乳牙玻璃复合修复体微渗漏的影响-体外研究
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3311
Halah Abdulkareem Alkhawaja, A. A. Al Haidar
{"title":"Effect of a novel coating material on the microleakage of glass hybrid restoration in primary teeth – An in vitro study","authors":"Halah Abdulkareem Alkhawaja, A. A. Al Haidar","doi":"10.26477/jbcd.v35i1.3311","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3311","url":null,"abstract":"Background: Glass ionomer restorations are widely employed in the field of pediatric dentistry. There is a constant demand for a durable restoration that remains functional until exfoliation. This study aimed to measure and compare the effect of a novel coating material (EQUIA Forte Coat) on the microleakage of glass hybrid restoration (EQUIA Forte HT) in primary teeth. Material and method: Thirty cavitated (class-II) primary molars were allocated randomly into two groups based on the coat application; uncoated (control) and coated group (experimental). Cavities were prepared by the use of a ceramic bur (CeraBur) and restored with EQUIA Forte HT with or without applying a protective coat (EQUIA Forte Coat). Samples went through the thermocycling process and dipped in 2% methylene blue dye before being sectioned through the center of the restoration. Microleakage was evaluated digitally using software and a camera connected to a stereomicroscope (30 x magnification) to assess dye penetration of the sectioned samples at both the occlusal and gingival marginal levels. Results: There was a significant difference between the coated and uncoated groups at both occlusal (p=.029) and gingival margin sites (p=.001). Conclusion: Higher microleakage values were associated with the uncoated group compared to the coated one. The application of a protective coating to the restorations is an efficient approach to decrease the microleakage of the restorations that can be usefully adopted in clinical practice.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78136646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salivary protein carbonyl and selected antioxidants in relation to dental caries among pregnant women 唾液蛋白羰基和抗氧化剂与孕妇龋齿的关系
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3312
B. H. Awn
{"title":"Salivary protein carbonyl and selected antioxidants in relation to dental caries among pregnant women","authors":"B. H. Awn","doi":"10.26477/jbcd.v35i1.3312","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3312","url":null,"abstract":"Background: Pregnancy is a physiological condition that affects the general and oral health.It is also associated with an increase in oxidative stress, which may presispose to oral diseases including dental caries. Aim of the study: This study aimed to measure salivary protein carbonyl, glutathione peroxidase and selenium levels of women who are pregnant and their association with dental caries in comparison to non-pregnant women, and to find out the mostly affected biomarker of oxidative stress during pregnancy. Subjects, materials and methods: A cross-sectional research was performed for a samples of 30 pregnant and 30 non-pregnant women who were chosen from city of Baghdad's Primary Healthcare Centers. Both groups aged 25-30 years. In unstimulated salivary samples protein carbonyl and glutathione peroxidase were determined colorimetrically using spectrophotometer by utilizing ready-made assay kits. Salivary selenium level was obtained by atomic absorption spectrophotometer. Plaque index had been used to determine the thickness of dental plaque. Caries was recorded using the Decayed, Missing, and Filled (DMF) index. described by WHO in 1997. Data was statistically analyzed using descriptive statistics method and Student's t-test, Wilcoxon sum rank test and Spearman’s correlation in addition to Receiver Operating Characteristics Curve (ROC test) (α=5%). Results: The plaque index and salivary protein carbonyl values were significantly higher among pregnant while salivary selenium and glutathione peroxidase recorded significantly lower levels among pregnant women. Dental caries parameters were higher among pregnant with significant difference for MS fraction only. ROC area for protein carbonyl equal one with highest sensitivity and specificity. Conclusion: Pregnant women recorded higher dental caries severity with higher salivary protein oxidation but lowers salivary antioxidant defense mechanisms. Salivary protein carbonyl is more ideal, valid and mostly affected biomarker in revealing the oxidative stress status during pregnancy","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89411965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Different methods of canine retraction- Part 2 犬科动物的不同缩回方法-第2部分
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3314
Mohammed Nahidh, Yassir A. Yassir, Grant T. McIntyre
{"title":"Different methods of canine retraction- Part 2","authors":"Mohammed Nahidh, Yassir A. Yassir, Grant T. McIntyre","doi":"10.26477/jbcd.v35i1.3314","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3314","url":null,"abstract":"Background: This review aims to discuss various canine retraction techniques using frictionless mechanics. Methods: Between 1930 and February 2022, searches were conducted about various canine retraction techniques using fixed orthodontic appliances in various databases, including PubMed Central, Science Direct, Wiley Online Library, the Cochrane Library, Textbooks, Google Scholar, Research Gate, and manual searching. Results: After removing the duplicate articles, publications that described how to use archwires to perform canine retraction with the archwires were included. Conclusions: The pros and cons of various canine retraction techniques using archwires were thoroughly discussed. T-loop is the preferred spring of all because of its characteristics","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135598950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Anti-inflammatory effects of manuka honey on salivary cytokines (clinical study) 麦卢卡蜂蜜对唾液细胞因子的抗炎作用(临床研究)
Journal of baghdad college of dentistry Pub Date : 2023-03-15 DOI: 10.26477/jbcd.v35i1.3310
M. W. Al-Kubaisi, B. Al-Ghurabi, Waqar Alkubaisy, N. Abdullah
{"title":"Anti-inflammatory effects of manuka honey on salivary cytokines (clinical study)","authors":"M. W. Al-Kubaisi, B. Al-Ghurabi, Waqar Alkubaisy, N. Abdullah","doi":"10.26477/jbcd.v35i1.3310","DOIUrl":"https://doi.org/10.26477/jbcd.v35i1.3310","url":null,"abstract":"Background: Manuka honey (MH) is a mono-floral honey derived from the Manuka tree (Leptospermum scoparium). MH is a highly recognized for its non-peroxide antibacterial activities, which are mostly related to its unique methylglyoxal content (MGO) in MH. The beneficial phytochemicals in MH is directly related to their favorable health effects, which include wound healing, anticancer, antioxidant, and anti-inflammatory properties. Aims: The purpose of this study was to evaluate the effect of MH on pro-inflammatory cytokines (IL-8 and TNF-α) in patients with gingivitis and compare it with chlorhexidine (CHX) and distilled water (DW). Materials and Methods: This study was a randomized, double blinded, and parallel clinical trial. Forty-five young participants aged (20–40) years were randomly selected and allocated into three groups: MH, CHX, and DW mouthwash groups. Each participant was given a random bottle. Five milliliters each of honey-based mouthwash formulation, CHX mouthwashes (0.2%) and DW were used twice daily for 21 days. All the participants were examined twice, once on the zero day (base line) and once after 21 days. Before and after each participant's mouthwash use IL-8 and TNF-α were measured using enzyme-linked immunosorbent assay (ELISA). Results: The results revealed a drop in the level of interleukin-8 in the manuka honey group which was statistically significant, but the decrease in the same biomarker in the chlorhexidine group was insignificant statistically. TNF-α levels were found to be insignificantly reduced in both the MH and CHX groups (P˃0.05). The DW group, on the other hand, obtained the opposite outcome in both biomarkers. Conclusion: Mouthwash containing MH had an anti-inflammatory impact, indicating an immunomodulatory action. These signs may be encouraging and promising for the use of MH in treating gingivitis.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"122 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77302814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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