Noor Ibrahim Dhaidan, Ghada Ibrahim Taha, Maher Al Shayeb
{"title":"Potential role of matrix metalloproteinase-8 as a predictive marker for peri-implant mucositis progress","authors":"Noor Ibrahim Dhaidan, Ghada Ibrahim Taha, Maher Al Shayeb","doi":"10.26477/jbcd.v37i2.3962","DOIUrl":"https://doi.org/10.26477/jbcd.v37i2.3962","url":null,"abstract":"Background: Osseointegrated dental implants have become increasingly common as a treatment option for missing teeth. Peri-implant infections are caused by bacterial plaque that may initiate an inflammatory release of cytokines, enhance accumulation of neutrophils in implant lesion, and trigger the production of matrix metalloproteinase-8 (MMP-8). MMP-8 is essential in inflammatory and degenerative processes of periodontal tissues and produced by activated cells. The purpose of this study was to detect the role of MMP-8 as a biomarker of active and aggressive peri-implant mucositis. Material and method: Eighty subjects (40 with peri-implant mucositis and 40 with successful and healthy peri-implant mucosa) were enrolled in this study. The 42 male and 38 female subjects were attended at AL-Karama and AL-Ma'amoun Specialized Dental Centers in Baghdad, Iraq from November 24, 2021 to May 25, 2022. Follow-up examinations were performed on patients to monitor the progression of disease. Peri-implant sulcular fluid was examined and identified using enzyme-linked immunosorbent assay technique for MMP-8. Results: Results showed that MMP-8 levels continue to rise after 3 weeks and are significantly higher in the patient group (P=0.00000) than the group with successful implants. Conclusion: MMP-8 can be used to reflect, associate, and predict clinical disease activity and progression of peri-implant mucositis properly.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"37 2","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/download/3962/1204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147884583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayat Mohammed, Raghad Fadhil, Maha Sh Mahmood, Haider A Al-Waeli
{"title":"Diagnostic biomarkers for periodontitis (observational case-control study)","authors":"Ayat Mohammed, Raghad Fadhil, Maha Sh Mahmood, Haider A Al-Waeli","doi":"10.26477/jbcd.v36i2.3673","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3673","url":null,"abstract":"Background: Early detection of periodontal tissue loss prevents further development and halts additional damage. The purpose of this study was to investigate the diagnostic ability of salivary Pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP) and deoxypyridinoline (DPD) in differentiating periodontitis from periodontal health. Material and method: A case-control included 80 participants who were divided into two groups: 40 periodontitis patients and 40 subjects with a healthy periodontium. Salivary samples were collected from each patient, followed by a clinical examination. The collected saliva samples were centrifuged and frozen at -80⁰C until analysis using Enzyme-Linked Immunosorbent Assay. Results: the results indicated that both biomarkers were effective in diagnosis periodontitis. The area under the curve (AUC) for ICTP was 0.99 and the proposed cut-off point was 6.6 ng/ml, while for DPD the AUC was 0.95 and the proposed cut-off point was 211.5 nmol/L. Conclusion: Salivary ICTP and DPD demonstrated diagnostic ability in distinguishing periodontitis from a healthy periodontium, making them valuable tools in early detection and management of periodontal diseases.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"78 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141337771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the effect of barium titanate nanofiller addition on the thermal conductivity and physio-mechanical properties of maxillofacial silicone","authors":"Y. M. Kareem, T. I. Hamad, Matheel AL-Rawas","doi":"10.26477/jbcd.v36i2.3674","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3674","url":null,"abstract":"Background: Silicone elastomers have been extensively used as the most acceptable material in the manufacturing of maxillofacial and other kinds of prosthetic devices. The durability of maxillofacial prostheses depends on the material chosen, the patient's attitude and feelings regarding the prosthesis, and how they perform for specific needs. Aims: This study aimed to investigate the influence of adding barium titanate (BaTiO3) nanoparticles on the mechanical and physical characteristics of room-temperature-vulcanized (RTV) VerSilTal (VST-50) maxillofacial silicone elastomer, including thermal conductivity, tear strength, and water absorption and solubility. Materials and methods: 0.5 wt% and 0.75 wt% BaTiO3 nanoparticles were added to RTV VST-50 platinum silicone elastomer. Ninety specimens were prepared and divided into three main groups: one control group and two experimental groups (0.5 and 0.75 wt%). The collected data were statistically analyzed by one-way ANOVA and Tukey (HSD) test (significant level at P ≤ 0.05). The homogeneity and normal distribution of data were assessed by Levene's and Shapiro Wilk's tests, respectively. Result: Both experimental groups showed a remarkable increase in tear strength, thermal conductivity, and water absorption compared with the nonadditive control group. For solubility, the group of 0.5 wt% additive showed an insignificant increase, whereas the group of 0.75 wt% showed a significant increase compared with the control group. Conclusion: The addition of BaTiO3 nanoparticles to RTV VST-50 enhanced the thermal conductivity and tear strength. Water absorption and solubility were also increased, but the values were clinically insignificant. FTIR revealed no chemical interaction between BaTiO3 and silicone. FE-SEM showed the uniform scattering of BaTiO3 inside the silicone matrix.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141336408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the influence of Ti6Al4V alloy particles on mechanical properties of heat-cured PMMA","authors":"Nihad H AlFuraiji, S. Altaie, S. Qasim","doi":"10.26477/jbcd.v36i2.3676","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3676","url":null,"abstract":"Background: Titanium alloy (Ti6Al4V) is considered a promising material for prosthetic dental applications due to its superior density, high strength, improved corrosion resistance and superior biocompatibility. Due to the low strength and brittleness of the practicable denture foundation material in heat-cured acrylic resin, improving the strength properties is a crucial issue. The present study aimed to evaluate the influence of Ti6Al4V alloy particles on the tensile strength transverse strength, and the surface hardness of heat-cured PMMA as a base material. Materials and methods: A total of 75 specimens were prepared by combining heat-cured acrylic resin with Ti6Al4V additive particles (0.5, 1, 1.5, and 2 wt. % respectively). Each group was subdivided into three subgroups according to the samples subjected to the test (n = 25), tensile strength; transverse strength; and surface hardness. Results: The result showed a significant difference (P= 0.007) in all tested groups. The results showed that the addition of Ti6Al4V particles to heat-cured material considerably increased the tensile strength, transverse strength, and surface hardness-a compared to the untreated control specimens. Conclusion: It was found that increasing the weight concentration (wt.) of Ti6Al4V particles improved the tensile strength, transverse strength, and surface hardness of heat-cured PMMA specimens.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"79 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141338003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gene polymorphisms for patients with Class III malocclusion. A pilot study","authors":"Aqeel M Bahya, Mushriq F Abid, Elham Alsahafi","doi":"10.26477/jbcd.v36i2.3675","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3675","url":null,"abstract":"Background: The interactions of genetic and environmental factors may account for the variability in the expression of malocclusion. The study of malocclusion etiology is fundamental to understand the biology underlying craniofacial growth and dental relations. Understanding biology will improve progress toward effective treatment and prevention, thereby decreasing the burden of this condition. Aims: The present study was set out to investigate the association of the single nucleotide polymorphisms (SNPs) in different genes (rs2249492 in COLA1A, rs4434184 in SOX2, rs2162540 in FGFR2, rs11696257 in MAFB, and rs881301 in FGFR1) with Class III malocclusion. Materials and Methods: A total of 10 patients, comprising 5 with Skeletal Class I and 5 with Skeletal Class III malocclusion, were included in the present study. Salivary DNA samples were collected and analyzed using Sanger sequencing. Digital tracing was performed on lateral cephalometric radiographs by using AutoCAD software for digitization to assess the anterio-posterior and vertical relationship of the maxillary and mandibular arch. Results: Out of five genes polymorphisms only two genes polymorphisms (SOX2 and FGFR1) showed an association with Cl.III malocclusion. Conclusion: This study reveals that SOX2 and FGFR1 genetic polymorphisms may be responsible for Class III malocclusion. However, more study with a larger participant pool is required to confirm these findings.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"10 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141336711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noor AM Ali, L. Nissan, Amar H Khamis, Nameer Al-Taai
{"title":"Enamel demineralization around Orthodontic brackets bonded with new bioactive composite (in-vitro study)","authors":"Noor AM Ali, L. Nissan, Amar H Khamis, Nameer Al-Taai","doi":"10.26477/jbcd.v36i2.3678","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3678","url":null,"abstract":"background: This study aimed to evaluate the effect of bioactive composite (ACTIVA) on enamel demineralisation when used as an orthodontic adhesive, compared to other adhesives. Materials and methods: Human upper premolars (n=64) were randomly divided into two equal groups; the first group stored the bonded teeth in deionised water for 30 days at 37°C, and the second group exposed the bonded teeth to acidic media. Each group was further subdivided into four subgroups, with eight premolars in each subgroup, based on the type of adhesive used to bond metal brackets: non-fluoride-releasing adhesive (Transbond XT), fluoride-releasing adhesive (Light Bond), light-cured, resin-reinforced glass ionomer (GC Fuji ortho LC), and bioactive restorative composite (ACTIVA BioACTIVE-RESTORATIVE). Enamel demineralisation was assessed at baseline and after 30 days with a laser fluorescence device (DIAGNOdent™ Pen). Results: There were significant differences in fluorescence variation values (ΔFV) among all four tested adhesive systems in both water and acid groups after 30 days. Light Bond adhesive showed the highest fluorescence variation value, while glass ionomer showed the lowest, indicating less enamel demineralisation around the bracket. ACTIVA had less enamel demineralisation in acidic media. However, there was no significant difference in enamel demineralisation between water storage and acidic media groups. Conclusion: ACTIVA (RMGIC + composite) exhibited less enamel demineralisation than Light Bond; however, Fuji ortho LC showed the lowest enamel demineralisation.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141336132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noor R. Al-Hasani, Sumayah Abdul-Jabbar, Ali I Ibrahim
{"title":"Validity of digital interceptive orthodontic/therapeutic protocols post global pandemics: A review","authors":"Noor R. Al-Hasani, Sumayah Abdul-Jabbar, Ali I Ibrahim","doi":"10.26477/jbcd.v36i2.3669","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3669","url":null,"abstract":"Background: Aggressive global pandemics such as COVID-19 can disrupt societies tragically, imposing a suspension to almost every field throughout the world; the orthodontic treatment and follow-up is no exemption. Objectives: To provide practical recommendations about resuming treatment for orthodontic patients during the “Return-to-Practice” phase and emphasize the validity of certain digital interceptive measures post global pandemics to minify the risk of infection spread. Materials and Methods: Sources of information pertaining to orthodontic/therapeutic implications during the COVID-19 pandemic were searched using electronic databases including COVID-19 Open Research Dataset (CORD-19 2020), Google Scholar, Scopus, PubMed, MEDLINE, reports from Centers for Disease Control (CDC), World Health Organization, in addition to recommendations by the American Association of Orthodontists (AAO) and British Orthodontic Society (BOS). Results: Many viruses are transmitted predominantly via droplets and secretions (cough, sneeze), providing the virus a path through the mucous membrane of the mouth, nose, and eyes. The virus can survive for days on plastic and stainless-steel objects. Tele-orthodontics has proven successful in performing many tasks that can be valid and helpful even post the pandemic. Conclusions: With the high expectations of a pandemic recurrence, attempts to reinforce tele-orthodontics, digital prescription and patient follow-up, and adherence to strict infection control measures are mandatory steps towards reducing contamination within dental/orthodontic practices.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"8 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141337207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The prevalence of periodontitis in an Iraqi population using the 2017 classification","authors":"Nada K Imran, H. Abdulbaqi, Mike Milward","doi":"10.26477/jbcd.v36i2.3668","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3668","url":null,"abstract":"Background: To determine the prevalence and severity of periodontitis in an Iraqi population using the 2017 classification. Methods: Data on the periodontal status of patients were retrospectively collected from healthcare records. The information included demographics, clinical parameters including bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment loss (CAL). Descriptive and inferential statistical analyses were performed using SPSS (version 26, IBM, USA) software. Results: Out of 1578 records, the periodontal health, gingivitis, and periodontitis represented 26.4%, 37.1%, and 36.5%, respectively with males more affected by periodontal disease compared with females. Periodontitis cases were dominated by stage 3 and 4 which combined accounted for 77.3%, followed by stage 2 (21.3%), and stage 1 (1.4%). When looking at disease grade and levels of stability, localized pattern, Grade C, and unstable status were the most prevalent domains. Regression analysis suggested age, BOP, male, and positive family history as predictors for increasing extent and severity of CAL both in periodontal health and disease. Conclusion: The prevalence of periodontal disease (periodontitis, and gingivitis) was almost equally expressed. Severe periodontitis was the most dominant group whilst milder forms of disease were least prevalent. The data indicated that demographic variables and clinical parameters could predict severity of attachment loss.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"88 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141337468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleep disorders and dental caries related to salivary alpha-amylase among dental students","authors":"Abrar A Ahmed, B. Diab, S. Razeghi","doi":"10.26477/jbcd.v36i2.3679","DOIUrl":"https://doi.org/10.26477/jbcd.v36i2.3679","url":null,"abstract":"College students experience several sleep problems, which may impact academic performance and health including dental health. The purpose of the study was to assess the effect of sleep disorders on dental caries status related to salivary alpha-amylase among dental students. Methods: A cross-sectional comparative study was done among dental students, aged 22 to 23 years attending the College of Dentistry, Al- Kufa University, 270 students have participated in this study. A questionnaire completed by those students was used to collect information about sleep disorders using Pittsburg sleep quality index. According to Manji et al (1989) criteria, teeth affected by dental caries were recorded. Unstimulated salivary samples were chemically analyzed for the detection of alpha-amylase using Enzyme Linked Immuno-Sorbent Assay. Results: It was found that the prevalence of poor sleep quality among dental students was 58.9% while the prevalence of dental caries in students with good sleep quality (75.68%) was higher than that for students with poor sleep quality (71.07%), also founded decay,missing and filling surfaces and decay level three of caries severity were significantly higher for students who had a good sleep quality. The mean value of salivary alpha-amylase was higher for students who had poor sleep quality yet difference was not significant. Conclusion: Caries experience was significantly higher among students with good sleep quality that was not affected by salivary amylase.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"3 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141336370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Salivary irisin in relation to recurrent aphthous ulcerand weight status in Diyala city/Iraq","authors":"Ayat K. Taher, N. Radhi","doi":"10.26477/jbcd.v36i1.3587","DOIUrl":"https://doi.org/10.26477/jbcd.v36i1.3587","url":null,"abstract":"Background: Recurrent aphthous stomatitis remains the most common ulcerative disease of the oral mucosa that exists as painfull round shallow ulcers with a well-defined erythematous margin and a yellowish grey pseudomembranous centre. Salivary irisin is an identified adipomyokine and research has revealed that it has an anti-inflammatory effect and is a novel myokine; it is synthesized in skeletal muscle and adipose tissue. The aim of the present study was to evaluate the relation of salivary irisin to recurrent aphthous ulcers and weight status in Diyala City / Iraq. Materials and methods: A cross-sectional comparative study was carried out during the period from the end of December (2021) until the end of March (2022). The total sample size composed of all patients attending a specialised dental center in Ba’aquba / Diyala governorate with recurrent aphthous ulcers of both gender and ages ranged from 20-30 years (100 patients consider the study group) assessed according to the directions suggested by the WHO (1997) and compared to the control group free from this lesion (100 patients consider the control group) matching in age and sex. The weight status was assessed using the digital weight scale. The sub samples of 45 from each study and the control group were selected to analyse salivary irisin. The description of data, presentation, and analysis process is carried out through the use of the SPSS package (SPSS version 22, Chicago, Illinois, USA). For the quantitative variable mean, the standard deviation (SD) was used. Frequency and percentage are used for the qualitative variable. The independent sample T test was used for the difference between the two groups. Pearson’s correlation was used for the linear correlation between two quantitative variables. Results: The highest percentage of recurrent aphthous ulcer was found in the lower lip. The mean value of irisin was higher among the study group than in the control group. The mean value of the body mass index among the control group was higher than that of the study group. When correlating the body mass index with salivary irisin, it is a positive weak not significant correlation. Conclusions: This study concluded that there is an elevated level of irisin among recurrent aphthous ulcers, in addition to that, the recurrent aphthous ulcer decreases the body mass index.","PeriodicalId":15041,"journal":{"name":"Journal of baghdad college of dentistry","volume":"86 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140238131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}