{"title":"Comment on \"Prevention of postoperative nausea and vomiting with rapid sequence induction and intubation in patients undergoing thyroidectomy: a randomized controlled trial\".","authors":"Zhiyang Li, Tiejun Li","doi":"10.1007/s00540-026-03912-8","DOIUrl":"https://doi.org/10.1007/s00540-026-03912-8","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149038631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of combination therapy with recombinant thrombomodulin and antithrombin on outcomes in patients with sepsis-induced disseminated intravascular coagulation in a surgical intensive care unit: a retrospective observational study.","authors":"Masashi Takakura, Tasuku Fujii, Tomoya Taniguchi, Akitaka Saito, Shogo Suzuki, Koichi Akiyama","doi":"10.1007/s00540-026-03903-9","DOIUrl":"https://doi.org/10.1007/s00540-026-03903-9","url":null,"abstract":"<p><strong>Purpose: </strong>Sepsis-induced disseminated intravascular coagulation (DIC) is associated with high morbidity and mortality. We evaluated the association of recombinant thrombomodulin (rTM) plus antithrombin (AT) with outcomes in adults with sepsis-induced DIC treated in a surgical intensive care unit (ICU).</p><p><strong>Methods: </strong>We conducted a single-center retrospective observational study between January 2018 and March 2025. Patients receiving rTM plus AT were compared with those receiving AT alone using 1:1 propensity-score matching. The primary outcome was 28-day all-cause mortality. Secondary outcomes included DIC resolution, ICU length of stay, and severe bleeding requiring transfusion. A predefined subgroup analysis evaluated patients undergoing surgery.</p><p><strong>Results: </strong>After matching, 45 patient pairs were analyzed. 28-day mortality was 11.1% (5/45) in the rTM + AT group and 15.6% (7/45) in the AT monotherapy group (relative risk, 0.71; 95% confidence interval, 0.24-2.08; log-rank p = 0.53). DIC resolution was more frequent with combination therapy than with AT monotherapy (88.9% vs. 66.7%; p = 0.02), whereas ICU length of stay did not differ significantly. Severe bleeding occurred in 13.3% and 33.3% of patients, respectively (p = 0.04). In the surgical subgroup, 28-day mortality was 6.9% (2/29) vs. 16.0% (4/25; log-rank p = 0.31), while DIC resolution was 93.1% vs. 64.0% (p = 0.02). Severe bleeding occurred in 17.2% and 40.0%, respectively (p = 0.08).</p><p><strong>Conclusion: </strong>Combination therapy with rTM and AT was associated with a higher rate of DIC resolution and a lower incidence of severe bleeding complications, including among surgical patients. However, no significant difference in 28-day mortality or ICU length of stay was observed.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to comments on \"predictive value of ultrasound-measured tongue base thickness for upper airway obstruction during monitored anesthesia care: a single-center prospective observational study\".","authors":"Koshiro Kikkawa, Motoi Takeuchi, Daiki Sakaguchi, Masayuki Nakamoto, Tatsuro Yokoyama, Hiroha Shibata, Ryohei Ito, Tomoaki Yatabe","doi":"10.1007/s00540-026-03888-5","DOIUrl":"https://doi.org/10.1007/s00540-026-03888-5","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdul Rahman, Jalaluddin Khan, Mohammad Ishrat, Mohd Rafi Lone
{"title":"Comment on 'Artificial intelligence-generated color overlay for ultrasound identification of the brachial plexus in regional anesthesia: an external validation study by Kamimura et al.'","authors":"Abdul Rahman, Jalaluddin Khan, Mohammad Ishrat, Mohd Rafi Lone","doi":"10.1007/s00540-026-03901-x","DOIUrl":"10.1007/s00540-026-03901-x","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In reply: what is the main cause of hypotension after induction of anesthesia with remimazolam in elderly patients?","authors":"Takashi Asai, Ryosuke Osawa, Reo Uchida","doi":"10.1007/s00540-026-03900-y","DOIUrl":"https://doi.org/10.1007/s00540-026-03900-y","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on 'Association between lactate-to-albumin ratio and postoperative delirium in elderly patients undergoing cardiac surgery' by Zhu et al.","authors":"Yaqian Zhu, Yanqin Guo, Xiaoxue You","doi":"10.1007/s00540-026-03905-7","DOIUrl":"10.1007/s00540-026-03905-7","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative perioperative pain assessment using PainVision<sup>®</sup> in carpal tunnel release: a retrospective observational study.","authors":"Takahiro Tanaka, Mitsuru Sato, Tomoaki Miyata, Kaito Tsuzuki, Ryo Yamashita, Soichiro Nomura, Yasuhiro Tanaka, Shinichiro Matsuyama, Takeaki Kawai, Hisayuki Hayashi, Masahiko Akiyama, Tomohisa Niiya, Keiichi Omote, Tetsuya Yamamoto","doi":"10.1007/s00540-026-03904-8","DOIUrl":"https://doi.org/10.1007/s00540-026-03904-8","url":null,"abstract":"<p><p>Objective assessment of perioperative pain remains challenging. The PainVision<sup>®</sup> device is designed to quantitatively estimate pain intensity, but its clinical utility for perioperative pain assessment following carpal tunnel release remains unclear. This retrospective study analyzed pain results for 21 hands in 17 patients who underwent carpal tunnel release. Pain intensity was assessed preoperatively and on postoperative day 1 using a visual analog scale (VAS) and the PainVision<sup>®</sup>-derived pain degree (PD). Both VAS and PD were significantly decreased on postoperative day 1 (p < 0.001 each; r = 0.74 each). Standardized magnitudes of change were similar for VAS (d<sub>av</sub> = 0.88) and PD (d<sub>av</sub> = 0.90). Patient-level sensitivity analysis accounting for bilateral cases yielded consistent findings (VAS, d<sub>av</sub> = 1.09; PD, d<sub>av</sub> = 1.18; p < 0.001 each). These findings suggest that PainVision<sup>®</sup>-derived PD can detect early perioperative changes of a magnitude comparable to those detected by VAS and may provide a quantitative measure complementary to subjective pain assessment following carpal tunnel release.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Prevention of postoperative nausea and vomiting with rapid sequence induction and intubation in patients undergoing thyroidectomy: a randomized controlled trial\" by Qiao et al. : Rapid sequence induction and postoperative nausea and vomiting.","authors":"Zhi-Bin Huang, Fei Gao, Fu-Shan Xue","doi":"10.1007/s00540-026-03897-4","DOIUrl":"10.1007/s00540-026-03897-4","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}