{"title":"Popliteal Pterygium Syndrome (Facio-Genito-Popliteal Syndrome)","authors":"N. Mariappan, S. Shetty","doi":"10.31907/2414-2093.2016.02.06","DOIUrl":"https://doi.org/10.31907/2414-2093.2016.02.06","url":null,"abstract":"Background: IRF6-related disorders span a spectrum from isolated cleft lip and palate and Van der Woude syndrome (VWS) at the mild end to popliteal pterygium syndrome (PPS) at the more severe end. Popliteal pterygia are found in popliteal pterygium syndrome, multiple pterygium syndrome and Arthrogryposis. The popliteal pterygium syndrome is a rare congenital condition, in which the patient has facial, genitourinary and skeletal anomalies along with popliteal pterygium. Autosomal dominant popliteal pterygium syndrome (AD-PPS) is a rare genetic malformation disorder characterized by cleft lip, with or without cleft palate, contractures of the lower extremities, abnormal external genitalia, syndactyly of fingers and/or toes, and a pyramidal skin fold over the hallux nail. AD-PPS is associated with mutations in the IRF6 gene (1q32.2-q32.3), involved in the formation of connective and epithelial tissues. Almost all affected patients harbor mutations in this gene. The word ‘pterygium’ is derived from the Greek word pterygion, which means wing. Pathologically it denotes a wing-like abnormal band of tissue. The most obvious characteristics of this syndrome are popliteal pterygium and a triangular crease of skin over the hallux. The orofacial findings include cleft lip, cleft palate, lower lip pits, a few missing teeth, and severely decayed teeth. The dental problems are overshadowed by the major syndromic manifestations. These patients have special dental needs and early preventive dental care and appropriate dental treatment at the optimal time is important. Diagnosis of pterygium syndrome is based on the clinical findings and confirmed by molecular genetic testing. AD-PPS is highly associated with missense mutations that alter residues that are predicted to interact directly with DNA in exons 3 and 4 of IRF6. Conclusion: An understanding of the molecular genetic basis of this syndrome is essential for prenatal diagnosis and also for genetic counseling of the parents. Keywords: Popliteal pterygium syndrome, Escobar syndrome, Magnetic resonance imaging, Congenital contractures, Genetic counseling.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83137611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. N. Yogishwarappa, S. Srinivasan, S. Teoh, A. Vijayakumar, M. Ishwar
{"title":"Customized Osteomesh Cranioplasty","authors":"C. N. Yogishwarappa, S. Srinivasan, S. Teoh, A. Vijayakumar, M. Ishwar","doi":"10.31907/2414-2093.2016.02.05","DOIUrl":"https://doi.org/10.31907/2414-2093.2016.02.05","url":null,"abstract":"Cranioplasty, one of the oldest surgical procedures used to repair cranial defects, has undergone many revolutionary changes over time to find the ideal material to improve patient outcome. The surgical challenge in repairing large calvarial defects is known to craniofacial surgeons. Ongoing researches on various cranioplasty materials continue with the help of recent technology. Stem cell experiments and development of morphogenic proteins are expected to take the lead in future. With the aid of Computer Aided Designing technology, all currently used alloplastic materials can be custom made for even large skull defect. We present a case of young female patient following trauma underwent craniotomy and complicated with bone graft loss. Patient initially underwent cranioplasty using a PMMA implant, inspite of its excellent tensile strength was not proven to be effective it sustained fracture and got exposed. A customized osteomesh of polycaprolactone (PCL) with a titanium scaffold with bone morphogenic protein (BMP) was impregnated with stem cells was used in cranioplasty. This aided in osseoinduction, which was later proved by imaging. Empirically, there has been no ideal material for cranioplasty; however, materials that are strong, resistant to infection, radiolucent, inexpensive, and able to reincorporate with a patient's craniotomy defect will offer the greatest advantages for such patients and hence PCL with such qualities proves to be a good alternative. Keywords: Cranioplasty, Composite graft, Osteomesh, Stem cells.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"2073 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91330258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heminasal Aplasia, a Rare Congenital Anomaly of Nose: Case Report and Review of Management Strategies","authors":"S. S. Shirol","doi":"10.31907/2414-2093.2016.02.04","DOIUrl":"https://doi.org/10.31907/2414-2093.2016.02.04","url":null,"abstract":"Heminasal aplasia is a rare congenital anomaly of nose that has rarely been reported in the English literature. The surgical management remains a challenge due to its rarity and lack of uniform management guidelines. We report a case of heminasal aplasia, managed successfully at our institute and systematic review of the available literature. Keywords: Heminasal aplasia, Hemi-arhinia, Aplasia nose, Arhinia, Absent nose, Half nose, Reconstruction, Anomaly of nose, Nasolabial flap, Folded nasolabial flap.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88390853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tourniquet in Plastic Surgery","authors":"Yogishwarappa Cn, A. Vijayakumar","doi":"10.31907/2414-2093.2016.02.03","DOIUrl":"https://doi.org/10.31907/2414-2093.2016.02.03","url":null,"abstract":"Tourniquet is invaluable instrument to plastic, hand and orthopedic surgeon. It helps create a bloodless field for easy operation and reduces operative time. The advantages of tourniquet is no without its share of complication including nerve and skin injuries and devastating vascular lesions leading to amputation or death. A thorough understanding of the local and systemic effect of tourniquet is essential to minimize the complication. Various physical and pharmacological modifications reduce the reperfusion injury and also help increase tourniquet time. This review discusses the principle, physiology and complications of tourniquet. Keywords: Tourniquet, Limb occlusion pressure, Reperfusion injury, Nerve palsies, Limb protector sleeves.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85156173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laser Diodo 800nm and Hirsutism in Darker Skinned Patients: Our Experience on 552 Women","authors":"A. Scilletta, G. Pompili","doi":"10.31907/2414-2093.2016.02.01","DOIUrl":"https://doi.org/10.31907/2414-2093.2016.02.01","url":null,"abstract":"Hirsutism is defined as excessive hair growth in areas usually associated with male sexual maturity, that is, on the face, chest, linea alba, lower back, buttocks, and anterior thighs. Hirsutism results from androgenic effects on the pilosebaceous unit and is commonly associated with acne and oily skin. In addition to being a source of social embarrassment, hirsutism may also be a cutaneous sign of a systemic disease. The severity of hirsutism depends on an underlying disorder resulting in excess production or increased availability of potent or weak androgens (testosterone, dehydroepiandrosterone (DHEA) and androstenedione). This study was designed to examine the safety and efficacy of laser hair removal using the LightSheer Diode EP Laser System on 552 women with hirsutism treated at the Andromeda Medical Office, Acireale, Italy from September 2008 till May 2015. In this study LightSheer ET by Lumenis induced a significant rapid hair growth reduction that increased at long-term follow-ups. Crusting was most common among women with thick black hair whose entire facewas treated. In all the cases, however, these side effects disappeared within three days without causing any permanent hypopigmentation or hyperpigmentation. The majority of patients experienced some pain during the procedure. Keywords: Hirsutism, Diodo, Lightsheer, Women, Hairs.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80269340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Review of Most Current Therapy for Large Area of Hypertrophic Scar and Keloid","authors":"G. Feng, Wang Xi-qiao","doi":"10.31907/2414-2093.2015.01.7","DOIUrl":"https://doi.org/10.31907/2414-2093.2015.01.7","url":null,"abstract":"For the large area scar or keloid, the treatment is still posing a great challenge. Because the invasive therapy has an unbearable pain and increased risk of side effect, like the steroid injection and cryotherapy, so the non-invasive therapy is actually the optimal choice for large area scar and children patients. Here we introduce the major modalities for the treatment of large area scar, like pressure therapy, Silicone, Onion extract, and scar massage. In addition, three aspects are recommended for the scar therapy: early use, combination use and persistent use, which is essential for a successful scar treatment. Keywords: Hypertrophic scar, Keloid, Scar treatment, Large area scar.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82897537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Massa, T. Massa, A. Peirano, P. Santi, S. Franchelli
{"title":"Autologous Grafts for the Correction of Breast Contour Deformities after Breast Reconstruction","authors":"M. Massa, T. Massa, A. Peirano, P. Santi, S. Franchelli","doi":"10.31907/2414-2093.2015.01.6","DOIUrl":"https://doi.org/10.31907/2414-2093.2015.01.6","url":null,"abstract":"Background: Breast oncologic treatments often lead to disfiguring breast contour deformities and tissues damage. The necessity to obtain an oncological radicality should be associated to an acceptable cosmetic outcome. Fat grafting is an effective technique, however in selected cases is not indicated, therefore other techniques should be investigated. Methods: Five patients that underwent reconstruction after mastectomy have been evaluated. Breast deformities were filled with autologous grafts derived from peri-prosthetic capsule, dermoadipose tissue or both. They underwent ultrasonographic exam before and after surgery (medium 9 months) to evaluate the stability and vitality of the grafts, furthermore the thickness and vascularization of breast regions to be corrected. The aesthetic outcome was evaluated by patients and a panel of surgeons. Results: Subcutaneous tissue thickness increase resulted at Ultrasonography in all cases except one, while vascular spots were maintained in one case. Regarding the cosmetic results all cases were judged as good-excellent by the surgeon. Patients were all satisfied with the improvements obtained. Conclusions: The technique allows to obtain a great aesthetic improvement and a good satisfaction degree of patients, without the addition of recovery days or treatment sessions. It could be considered a valid alternative when other techniques are not applicable. Keywords: Breast reconstruction, Autologous graft, Ultrasonography, Peri-prosthetic capsule.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88636414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Hernanz, M. Fidalgo, P. Muñoz, M. G. Noriega, M. Gómez‐Fleitas
{"title":"Is there Enough Justification for Questioning Body Mass Index (BMI) as Exclusion Criteria of Reduction Mammoplasty in the Surgical Treatment of Symptomatic Macromastia?","authors":"F. Hernanz, M. Fidalgo, P. Muñoz, M. G. Noriega, M. Gómez‐Fleitas","doi":"10.31907/2414-2093.2015.01.5","DOIUrl":"https://doi.org/10.31907/2414-2093.2015.01.5","url":null,"abstract":"Background: Despite the fact that reduction mammaplasty is an effective and efficient treatment to symptomatic macromastia, frequently, women demanding this treatment are accepted or not depending on body mass index criteria. The aim of this work was to compare changes of quality of life on obese and no-obese women who undergoing breast reduction mammaplasty. Methods: A prospective study was performed on 56 consecutive women undergoing bilateral reduction mammaplasty for symptomatic macromastia, 21 of them had a BMI lower than 30 (No-obese group) and 35 with 30 or higher BMI (Obese group). Short Form SF-36 quality of life questionnaires were answered at interviews a week before the surgery and six months after. To evaluate the change of quality of life we used “effect size”. Results: Preoperative SF36 scores did not make differences between both groups. Six months after surgery only postoperative physical score of no-obese patients was significantly higher than obese one (52.11 vs 48.47, p>0.05). Both groups increased clearly their quality of life showing an increment of all SF36 domains with an effect size ranged from 0.53 to 2.07. More than seventy percent of obese women improved their scores exceeding means of preoperative scores. Conclusion: According to our results and the fact that the main goal of the breast reduction is ameliorate the quality of life there is no justification for exclusion obese patients with BMI >30 who suffer from symptomatic macromastia from reduction mammaplasty. Therapy: Level III of Evidence. Keywords: Reduction mammaplasty, Symptomatic macromastia, Obese, SF-36 health questionnaire, Effect size.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"125 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72662675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rhomboid Flap: An Option to Many Anatomical Regions","authors":"Érico Pampado Di Santis","doi":"10.31907/2414-2093.2015.01.4","DOIUrl":"https://doi.org/10.31907/2414-2093.2015.01.4","url":null,"abstract":"Introduction: The rhomboid transposition flap can be used at any region on the body surface, and is widely used on reconstructive surgery. When it is used for surgical procedures in order to correcting facial defects, the Limberg’s flap produces good functional and aesthetic results, particularly when scars are positioned between the aesthetic units of the face. This article will describe the rhomboid flap technique and discuss the versatility, safeness, applicability and complications of Limberg’s flap for cutaneous reconstruction, which can be in a huge part of body segments Results and Discussion: The Limberg’s flap is a rhomboid transposition flap. The flaps are made by taking into account size and location of the original defect and elasticity of the surrounding tissue. From the resection defect resulting, a lozenge is drawn with internal angles of 60 degrees and 120 degrees and the closure is completed by transposing the flap towards the defect. This flap provides very good results to be executed with predictability, high safeness degree and low rate of complications. Keywords: Flap, Limberg, Reconstruction, Rhomboid, Surgery.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80319294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Enalapril on Hypertrophic Scars and Keloids","authors":"A. Vijayakumar, Hemang Sanghvi, Pavan Murdeshwar","doi":"10.31907/2414-2093.2015.01.3","DOIUrl":"https://doi.org/10.31907/2414-2093.2015.01.3","url":null,"abstract":"Scarring is a major concern to patient and surgeon following any kind of trauma. Excessive scarring can dramatically affect a patient’s quality of life, both physically and psychologically. Incidence rates of hypertrophic scarring vary from 40% to 70% following surgery to up to 91% following burn injury, depending on the depth of the wound. Most current treatment give unsatisfactory results. Recent studies have explored the role of tissue Angiotensin receptors in tissue healing. With potential benefit of Angiotensin converting enzyme inhibitors in preventing cardiac and pulmonary fibrosis, its role in cutaneous scarring needs to be explored. There is need for randomized control trials to study the role of Enalapril in cutaneous scarring. Angiotensin converting enzyme inhibitors and angiotensin receptor antagonist could be potential candidates for management of hypertrophic scars. Key words: Hypertrophic scars, Keloids, Angiotensin converting enzyme inhibitors, Enalapril.","PeriodicalId":14956,"journal":{"name":"Journal of Advanced Plastic Surgery Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87614959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}