JACC. Case reports最新文献_第9页

Percutaneous Retrieval of a Fractured Catheter Migrated via a Patent Foramen Ovale With High-Risk Morphology. 经卵圆孔未闭导管移位的高危形态经皮取出。

JACC. Case reports Pub Date : 2026-10-19 DOI: 10.1016/j.jaccas.2026.110637

Yuto Fujimura, Takao Morikawa, Ryo Shigeno, Fumiya Hasegawa, Atsushi Hirohata

{"title":"Percutaneous Retrieval of a Fractured Catheter Migrated via a Patent Foramen Ovale With High-Risk Morphology.","authors":"Yuto Fujimura, Takao Morikawa, Ryo Shigeno, Fumiya Hasegawa, Atsushi Hirohata","doi":"10.1016/j.jaccas.2026.110637","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110637","url":null,"abstract":"Background: A fractured central venous port catheter can rarely migrate into the left heart via a patent foramen ovale (PFO).Case summary: A man in his 70s presented with a fractured central venous port catheter. Electrocardiogram-gated contrast-enhanced computed tomography confirmed that the fragment straddled from the right ventricular apex, through a PFO, into the right upper pulmonary vein. Because direct snaring of the ends was considered difficult, percutaneous retrieval was performed under transesophageal echocardiography guidance using the wire-loop technique. The catheter was dragged into the inferior vena cava and successfully retrieved into a 16-F sheath.Discussion: In a situation where direct snaring was anatomically difficult, we successfully retrieved the fractured catheter with the wire-loop technique. Detailed preprocedural multimodality imaging of the PFO crossing significantly contributed to successful retrieval.Take-home messages: In patients with a PFO, a fractured catheter can migrate into the left heart. Preprocedural evaluation using multimodality imaging is crucial for safe retrieval.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110637"},"PeriodicalIF":0.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valve-in-Root TAVI vs Redo Surgery in a Young Adult With Failed Bioprosthesis. 根内瓣膜TAVI与重做手术治疗失败的年轻成人生物假体。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110733

Rushmi Purmessur, Luigia D'Errico, Charis Costopoulos, Jason Ali

{"title":"Valve-in-Root TAVI vs Redo Surgery in a Young Adult With Failed Bioprosthesis.","authors":"Rushmi Purmessur, Luigia D'Errico, Charis Costopoulos, Jason Ali","doi":"10.1016/j.jaccas.2026.110733","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110733","url":null,"abstract":"Topic of controversy: Whether valve-in-valve (ViV) transcatheter aortic valve implantation (TAVI) or redo surgical aortic valve replacement (SAVR) is preferred for structural valve degeneration of a Freestyle stentless aortic root in a young adult, and whether a Ross procedure at index surgery would have better served lifetime management.Case summary: A 30-year-old man with a failed stentless aortic root (implanted at age 20 for bicuspid aortic valve regurgitation) presented with severe bioprosthetic regurgitation and ventricular dilatation. Transfemoral ViV TAVI with a 29-mm Edwards SAPIEN 3 Ultra Resilia was performed successfully.Pro viewpoint: ViV TAVI avoids redo sternotomy, preserves future options, and aligns with patient preference to avoid anticoagulation.Con viewpoint: Redo SAVR with a mechanical valve-and a Ross procedure at the index operation-may offer superior lifetime sequencing, avoiding constraints of successive transcatheter implants.Take-home message: Lifetime planning must begin at the index operation; both ViV TAVI and redo SAVR require heart team deliberation with explicit consideration of all future interventions.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110733"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcatheter Edge-to-Edge Repair in Advanced Heart Failure and Ventricular Dysfunction: An Evolving Heart Team Strategy. 经导管边缘到边缘修复晚期心力衰竭和心室功能障碍：一种不断发展的心脏团队策略。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110759

Ahmed AlBadri, Moody Makar, James Burke, Salvotore Mannino, Jennifer Giuseffi, Rajnish Prasad, Gagandeep Joshi, Abdul Latif Bikak

{"title":"Transcatheter Edge-to-Edge Repair in Advanced Heart Failure and Ventricular Dysfunction: An Evolving Heart Team Strategy.","authors":"Ahmed AlBadri, Moody Makar, James Burke, Salvotore Mannino, Jennifer Giuseffi, Rajnish Prasad, Gagandeep Joshi, Abdul Latif Bikak","doi":"10.1016/j.jaccas.2026.110759","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110759","url":null,"abstract":"Background: Patients with severe left ventricular (LV) dysfunction and mitral regurgitation are underrepresented in pivotal transcatheter edge-to-edge repair trials and are often ineligible for transplantation or LV assist devices, leaving limited options when guideline-directed medical therapy fails.Case summary: We describe 6 patients aged 38 to 82 years with LV ejection fraction 10% to 20% and severe (4+) to torrential (5+) mitral regurgitation, 4 patients presenting in or near cardiogenic shock requiring inotropic, vasopressor, or intra-aortic balloon pump support. All underwent transcatheter edge-to-edge repair as our multidisciplinary heart team strategy evolved.Discussion: With increasing experience, the heart team incorporated individualized pharmacologic or temporary mechanical support, preprocedural hemodynamic optimization, and anatomy-driven device selection. One patient initially referred for palliative care was subsequently reassessed and treated. This series illustrates how iterative multidisciplinary learning may expand transcatheter edge-to-edge repair candidacy in carefully selected, high-risk patients with advanced heart failure and profound ventricular dysfunction and limited therapeutic alternatives.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110759"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First-in-Human Axillary Vein Implantation of a Leadless Pacemaker: Breaking the Access Barrier. 首次在人类腋窝静脉植入无铅起搏器：打破进入障碍。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110874

Lydia Messele, William Leon, Niailah Ochai, Gem Pulmano, Uma N Srivatsa

{"title":"First-in-Human Axillary Vein Implantation of a Leadless Pacemaker: Breaking the Access Barrier.","authors":"Lydia Messele, William Leon, Niailah Ochai, Gem Pulmano, Uma N Srivatsa","doi":"10.1016/j.jaccas.2026.110874","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110874","url":null,"abstract":"Background: Leadless pacemakers (LPs) are conventionally implanted transfemorally, with transjugular and subclavian routes reported as alternatives. Axillary access has not previously been reported.Fih summary: A 78-year-old woman with chronic sacral wounds became temporary-pacing dependent following an inferior ST-segment elevation myocardial infarction. An LP was selected given infection risk. Because of a right femoral deep venous thrombosis, an abscess at the left femoral site, and restricted neck mobility limiting internal jugular access, she underwent left axillary vein implantation of an LP.Discussion: Axillary access served as a feasible alternative route. A septal position was achieved by rotating the delivery system counterclockwise, opposite the transfemoral direction, while a perpendicular sterile table supported the extracorporeal catheter length.Novelty: This is the first reported axillary vein implantation of an LP.Take-home message: Axillary venous access is a feasible bailout route for LP implantation when femoral and internal jugular access are unavailable.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110874"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IVUS-Guided Tip Detection and Distal Anchor Assisted Stent Push for a Protruding Ostial Stent. ivus引导的尖端检测和远端锚定辅助支架推送用于突出的开口支架。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110771

Yoshitomo Tsutsui, Kota Tanaka, Tomohiro Yamasaki, Kiwamu Sudo, Yuta Nishimura, Satoshi Watanabe, Mutsumi Iwamoto, Yoshitaka Iwanaga, Heitaro Watanabe, Atsunori Okamura

{"title":"IVUS-Guided Tip Detection and Distal Anchor Assisted Stent Push for a Protruding Ostial Stent.","authors":"Yoshitomo Tsutsui, Kota Tanaka, Tomohiro Yamasaki, Kiwamu Sudo, Yuta Nishimura, Satoshi Watanabe, Mutsumi Iwamoto, Yoshitaka Iwanaga, Heitaro Watanabe, Atsunori Okamura","doi":"10.1016/j.jaccas.2026.110771","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110771","url":null,"abstract":"Objectives: Excessive aorto-ostial stent protrusion requires appropriate adjustment to achieve an optimal landing zone. We report a successful resolution using intravascular ultrasound (IVUS)-guided tip detection (TD) and the stent push technique under distal anchor balloon support.Key steps: A drug-eluting stent deployed at the right coronary artery ostium protruded excessively into the aorta, causing guiding catheter dislodgment. Using the IVUS-guided TD method, a guidewire was successfully advanced into the stent lumen. Under distal anchor balloon support, the stent push technique was performed to correct the protruding stent to an optimal position.Potential pitfalls: IVUS-guided TD enables real-time visualization of the proximal stent edge and wire tip, facilitating accurate rewiring. Distal anchor balloon support provides sufficient backup for effective longitudinal stent deformation.Take-home message: The IVUS-guided TD method combined with a distal anchor balloon-supported stent push technique is an effective strategy for managing excessive aorto-ostial stent protrusion.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110771"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopic Renal Denervation and Perirenal Adipose Tissue Debulking for Refractory Hypertension in End-Stage Renal Disease. 腹腔镜肾去神经和肾周脂肪组织减积治疗终末期肾病难治性高血压。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110641

Jiapeng Chu, Xiaolong Liu, Long Kuang, Hongxing Gu, Wenjun Xie, Zhihang Ni, Chunlai Shao

{"title":"Laparoscopic Renal Denervation and Perirenal Adipose Tissue Debulking for Refractory Hypertension in End-Stage Renal Disease.","authors":"Jiapeng Chu, Xiaolong Liu, Long Kuang, Hongxing Gu, Wenjun Xie, Zhihang Ni, Chunlai Shao","doi":"10.1016/j.jaccas.2026.110641","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110641","url":null,"abstract":"Background: Both renal sympathetic nerves and perirenal adipose tissue (PRAT) drive hypertension. However, evidence regarding renal denervation (RDN) in end-stage renal disease (ESRD) remains limited.First-in-human summary: A 74-year-old man with diabetic chronic kidney disease stage 5 presented with refractory hypertension despite treatment with 4 antihypertensive agents and intravenous nitroprusside. He underwent bilateral laparoscopic-assisted RDN combined with PRAT debulking without complications. At 5-month follow-up, office and ambulatory blood pressures were substantially reduced, while renal function and medications remained stable.Discussion: Our case provides preliminary evidence supporting the feasibility of a combined laparoscopic RDN and PRAT debulking strategy in a patient with ESRD and refractory hypertension.Novelty: To our knowledge, this is the first report of RDN combined with PRAT debulking using the laparoscopic system in ESRD.Take-home message: This combined intervention offers a promising new therapeutic option for refractory hypertension in patients with advanced kidney disease.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110641"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-Frequency Whole-Body Vibration and Isometric Exercise in Cardiac Rehabilitation: Improved Capacity and Triglyceride-Glucose Index. 心脏康复中的低频全身振动和等长运动：改善能力和甘油三酯-葡萄糖指数。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110535

Jiabin Pan, Rui Huang, Yueqiu Li, Jiawei Li, Jian Xiu

{"title":"Low-Frequency Whole-Body Vibration and Isometric Exercise in Cardiac Rehabilitation: Improved Capacity and Triglyceride-Glucose Index.","authors":"Jiabin Pan, Rui Huang, Yueqiu Li, Jiawei Li, Jian Xiu","doi":"10.1016/j.jaccas.2026.110535","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110535","url":null,"abstract":"Background: Exercise intolerance may persist in patients with chronic coronary syndrome despite successful percutaneous coronary intervention. Evidence regarding low-frequency whole-body vibration training (LF-WBVT) remains limited.Case summary: A 62-year-old woman underwent cardiac rehabilitation for reduced exercise capacity 1 year after percutaneous coronary intervention. Baseline peak oxygen uptake was 14.3 mL/kg/min. She completed an 8-week program consisting of moderate-intensity continuous aerobic training, LF-WBVT (3-9 Hz), and isometric lower-extremity resistance exercise. Peak oxygen uptake increased to 22.2 mL/kg/min, and oxygen pulse increased from 8.7 to 9.6 mL/beat. No major adverse cardiovascular events occurred.Discussion: This combined strategy improved both cardiorespiratory fitness and metabolic health. The triglyceride-glucose index reduction is a novel finding, suggesting lower future cardiovascular risk.Take-home messages: LF-WBVT with isometric exercise is safe in selected patients with chronic coronary syndrome. Triglyceride-glucose index may serve as a metabolic biomarker for rehabilitation outcomes.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110535"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late Progressive Multivalvular Regurgitation After Heart Transplantation With Preserved Graft Function. 保留移植物功能的心脏移植术后晚期进行性多瓣反流。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110562

Nicholas Fanous, Rita-Maria Abdo, Cobi Adams, James Healy, Aaron Adonopulos, Mayooran Namasivayam, Peter MacDonald, Alasdair Watson

{"title":"Late Progressive Multivalvular Regurgitation After Heart Transplantation With Preserved Graft Function.","authors":"Nicholas Fanous, Rita-Maria Abdo, Cobi Adams, James Healy, Aaron Adonopulos, Mayooran Namasivayam, Peter MacDonald, Alasdair Watson","doi":"10.1016/j.jaccas.2026.110562","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110562","url":null,"abstract":"Background: Late clinical decline after heart transplantation is commonly attributed to rejection, cardiac allograft vasculopathy, or ventricular dysfunction. Progressive structural valvular disease is less frequently emphasized when graft systolic function is preserved.Case summary: A 22-year-old woman underwent orthotopic heart transplantation at age 13 for familial restrictive cardiomyopathy. Nearly 10 years later, she developed progressive exertional fatigue, reduced exercise tolerance, and dizziness despite preserved graft systolic function and no significant cardiac allograft vasculopathy. Serial imaging demonstrated severe mitral regurgitation, moderate to severe aortic regurgitation, and moderate to severe tricuspid regurgitation. She underwent redo sternotomy with bioprosthetic aortic and mitral valve replacement and tricuspid repair, with preserved ventricular function and clinical recovery at early follow-up.Discussion: This case highlights progressive multivalvular disease as an important valve-level cause of late clinical decline after heart transplantation.Take-home message: Consider structural valvular disease in symptomatic long-term heart transplant recipients with preserved graft function.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110562"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Native Leaflet Interference After Transcatheter Mitral Valve-in-Ring: Snare-Assisted Valve-in-Valve-in-Ring Bailout. 经导管二尖瓣环内置换术后的原生小叶干扰：陷阱辅助环内置换术。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110737

Andrea Mangiameli, Valentina Bernardini, Alessia Azzano, Eligio Miccichè, Davide Cao, Andrea Cascella, Elvis Brscic

{"title":"Native Leaflet Interference After Transcatheter Mitral Valve-in-Ring: Snare-Assisted Valve-in-Valve-in-Ring Bailout.","authors":"Andrea Mangiameli, Valentina Bernardini, Alessia Azzano, Eligio Miccichè, Davide Cao, Andrea Cascella, Elvis Brscic","doi":"10.1016/j.jaccas.2026.110737","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110737","url":null,"abstract":"Background: Native mitral leaflet interference is a rare cause of acute intraprosthetic regurgitation after transcatheter mitral valve-in-ring replacement (TMViR).Case summary: An 83-year-old woman with previous surgical mitral annuloplasty underwent transseptal TMViR for severe regurgitation from anterior mitral leaflet flail. After implantation of a 32-mm Myval Octapro valve, severe intraprosthetic regurgitation developed. High atrial positioning and prosthesis tilting allowed the flail anterior leaflet to overhang the ventricular valve edge and impair prosthetic leaflet coaptation. Balloon postdilation failed and increased instability. A contralateral gooseneck snare enabled controlled recrossing and deeper valve-in-valve-in-ring implantation, with complete regurgitation resolution and no left ventricular outflow tract obstruction.Discussion: Native leaflet interference should be considered after TMViR when acute intraprosthetic regurgitation occurs.Take-home message: Snare-assisted recrossing may provide selective bailout when marked tilt or instability prevents safe conventional recrossing.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110737"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Staphylococcus aureus Purulent Myopericarditis and Cardiac Tamponade in a Patient With Systemic Lupus Erythematosus. 系统性红斑狼疮患者化脓性心肌炎和心脏填塞1例。

JACC. Case reports Pub Date : 2026-10-16 DOI: 10.1016/j.jaccas.2026.110729

Cooper Roslund, Lucy Checchio, Svenja Schneider, Isaac Daudelin, Mark DeCaro, Darius Farzad, Gregary D Marhefka

{"title":"Staphylococcus aureus Purulent Myopericarditis and Cardiac Tamponade in a Patient With Systemic Lupus Erythematosus.","authors":"Cooper Roslund, Lucy Checchio, Svenja Schneider, Isaac Daudelin, Mark DeCaro, Darius Farzad, Gregary D Marhefka","doi":"10.1016/j.jaccas.2026.110729","DOIUrl":"https://doi.org/10.1016/j.jaccas.2026.110729","url":null,"abstract":"Background: Purulent bacterial pericarditis (or myopericarditis) is a rare condition that can lead to the development of pericardial effusion and cardiac tamponade.Case summary: We report a complicated case of methicillin-sensitive Staphylococcus aureus myopericarditis complicated by cardiac tamponade in a young, immunocompromised patient undergoing treatment for systemic lupus erythematosus (SLE).Discussion: This case highlights how SLE and immunosuppression can predispose patients to rare, life-threatening infections such as purulent myopericarditis. We review potential mechanisms of how bacterial pathogens may seed the pericardial space, as well as different treatment options that should be considered, including intravenous and, in some cases, intrapericardial antibiotic delivery.Take-home messages: Purulent pericardial effusions can rapidly develop and progress to cardiac tamponade, hemodynamic instability, and death if not recognized promptly. SLE and immunosuppression are risk factors for the development of this rare condition.","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":" ","pages":"110729"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0