Journal Biomedical and Biopharmaceutical Research最新文献_第5页

Impact of the year of graduation on the positioning of nutrition professionals regarding the vegetarian diet Impacto do ano de formacilo no posicionamento dos profissionais de nutricao face a dieta vegetariana 毕业年份对营养专业人士对素食饮食定位的影响对营养专业人士对素食饮食定位的影响

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-03-01 DOI: 10.19277/BBR.18.1.248

Aline Ambrósio, L. Vasconcelos, Marta Raposo, C. Ferreira-Pêgo

{"title":"Impact of the year of graduation on the positioning of nutrition professionals regarding the vegetarian diet Impacto do ano de formacilo no posicionamento dos profissionais de nutricao face a dieta vegetariana","authors":"Aline Ambrósio, L. Vasconcelos, Marta Raposo, C. Ferreira-Pêgo","doi":"10.19277/BBR.18.1.248","DOIUrl":"https://doi.org/10.19277/BBR.18.1.248","url":null,"abstract":"The adoption of a vegetarian diet increased over the years. In Portugal, is estimated that 1.2% of the population follows this food pattern. A cross-sectional study was carried out, including a final sample of 74 nutrition professionals to assess their position concerning the vegetarian diet (VD) according to their year of graduation (YG). The results analyses demonstrated that 23 nutrition professionals graduated between 1980 and 2009; and 51 between 2010 and 2019. There were statistically significant differences regarding the possibility of keeping a VD throughout life, since 81.1% of the participants consider it possible, most of them belonging to the group who graduated after 2009. As for supplements, 13% of the nutrition professionals who graduated until 2009 believe it possible to adhere to a VD without resorting to supplements, however, the percentage increases significantly to 39.2% in nutrition professionals trained after 2009. The percentage of nutrition professionals that approved the adherence of athletes to VD increased statistically in recent years, however, most believe this adherence is only possible with the use of supplements. Adherence to VD has increased over the past few years, however, the opinion of nutrition professionals is not unanimous regarding its safety, effectiveness in weight loss, and use of supplementation.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83640294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Type 1 medication review based on a pharmacy’s electronic medication records: first steps towards an algorithm to stratify patients for tailored pharmacy services 基于药房电子用药记录的第1类药物审查:为定制药房服务对患者进行分层的算法的第一步

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-03-01 DOI: 10.19277/BBR.18.1.251

Lígia Reis, Miguel Monteiro, Luís Lourenço, João Gregório

{"title":"Type 1 medication review based on a pharmacy’s electronic medication records: first steps towards an algorithm to stratify patients for tailored pharmacy services","authors":"Lígia Reis, Miguel Monteiro, Luís Lourenço, João Gregório","doi":"10.19277/BBR.18.1.251","DOIUrl":"https://doi.org/10.19277/BBR.18.1.251","url":null,"abstract":"Algorithms, queries, and knowledge-based systems are among approaches to screen electronic patient records stored in databases and support pharmacist medication reviews. The aim of this study was to perform a type 1 medication review and identify clusters that enable the definition of an algorithm to tailor pharmacy professional interv A retrospective observational study was conducted on a convenience sample of pharmacy records. Records were included if patients had a medication dispensing history between June 2017 - July 2018 and used two or more chronic medications. Statistical analysis used a two-step cluster to identify common characteristics among fifty-five sets of patient records which underwent Type 1 medication review. The median number of drugs used per patient was five [IQR: 3.0 – 7.0]. 18.2% of patients had inappropriate drugs, and 30.9% had moderate or major interaction potential. Four clusters were identified based on the variables of interactions, number of drugs used, contraindications, Beers criteria and measurable biomarkers, allowing to envision possible pharmaceutical interventions, as well as the priority in providing that intervention. The identification of patient clusters via medication review of electronic records of pharmacy patients supports the design of criteria-based algorithms, likely to be automated.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84956773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Topically applied methyl nicotinate evokes a temporary inflammation on human skin 局部应用烟酸甲酯会引起人体皮肤的暂时炎症

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-01-01 DOI: 10.19277/bbr.18.1.257

L. Monteiro Rodrigues, Sérgio Faloni de Andrade, Clemente Rocha

{"title":"Topically applied methyl nicotinate evokes a temporary inflammation on human skin","authors":"L. Monteiro Rodrigues, Sérgio Faloni de Andrade, Clemente Rocha","doi":"10.19277/bbr.18.1.257","DOIUrl":"https://doi.org/10.19277/bbr.18.1.257","url":null,"abstract":"Some challengers such as methylnicotinate (MN) have been used in human models to study the anti-inflammatory effect of topical formulations. However, MN skin responses are still poorly understood and widely varied. In the present study we aim to contribute to better characterise those responses. Eight healthy participants were selected. All procedures were approved by the institutional Ethics Committee. Two aqueous MN dilutions (0.5% and 1.0%) were left in contact for 1 minute in the anterior forearm skin. Following exposure, skin reactions were clinically and biometrically assessed at 30, 60 and 120 minutes and compared with baseline. Measurements involved the ICDRG clinical score scale and select analytical technologies - laser Doppler flowmetry, Polarised Spectroscopy, Transepidermal Water Loss Meter, and High Resolution Sonography. Results have shown that MN application evoked a maximal response at 30 minutes with an increase in the ICDRG score between 1-2. Significant changes in TEWL and microcirculation were observed, as was an increased dermal hypoecogenicity (edema), detected by HRS. These effects are compatible with a localised short-duration inflammation and reinforce the interest of MN to be used as a safe and controllable challenger in human models.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85663816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Antioxidant activities and antidiabetic potential of extract of fruits from the Myrtaceae family: inhibitory effects on α-amylase and α-glucosidase activities 桃金桃科果实提取物的抗氧化活性和抗糖尿病潜力:对α-淀粉酶和α-葡萄糖苷酶活性的抑制作用

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-01-01 DOI: 10.19277/bbr.18.1.259

Simone Muniz Pacheco, Rejane Giacomelli Tavares, M. Seifert, L. Nora, Rafael de Almeida Schiavon

{"title":"Antioxidant activities and antidiabetic potential of extract of fruits from the Myrtaceae family: inhibitory effects on α-amylase and α-glucosidase activities","authors":"Simone Muniz Pacheco, Rejane Giacomelli Tavares, M. Seifert, L. Nora, Rafael de Almeida Schiavon","doi":"10.19277/bbr.18.1.259","DOIUrl":"https://doi.org/10.19277/bbr.18.1.259","url":null,"abstract":"There is a great diversity of plants which are grown in the Atlantic Forest region of Brazil that produce small, colorful, edible fruit that are used in empiric mode to treat several diseases, such as diabetes, as fruits are a rich source of dietary phenolic antioxidants. In this study, we investigated the inhibitory activity of methanolic fruit extracts from the Myrtaceae family - Psidium cattleianum (araçá), Syzygium cumini (jambolão), Campomanesia xanthocarpa (guabiroba), Eugenia uniflora (pitanga) and Eugenia pyriformis (uvaia) - against α-amylase and intestinal α-glucosidase (maltose and sucrose). The antioxidant activities were evaluated using two different in vitro assays: the 2,2’-azinobis(3-ethylbenzthiazoline-6-sulphonate) (ABTS) test and the 2,2’-diphenyl-1-picrylhydrazyl (DPPH) test. The extracts of P. cattleianum, S. cumini, E. pyriformis inhibited α-amylase activity between 13% and 60% (p<0.05). The extracts of P. cattleianum also inhibited α-glucosidase activity with either maltose or sucrose as substrate between 15% and 61% (p<0.05). Additionally, these fruits are rich in phenolic compounds with antioxidant activities.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84733610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body composition assessment of vegetarian-vegan and omnivore young women – an exploratory study 素食-素食和杂食年轻女性的身体成分评估-一项探索性研究

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-01-01 DOI: 10.19277/bbr.18.1.258

C. Ferreira-Pêgo, Rejane Giacomelli Tavares, Sofia Lopes, Tatiana Fontes, L. Monteiro Rodrigues

{"title":"Body composition assessment of vegetarian-vegan and omnivore young women – an exploratory study","authors":"C. Ferreira-Pêgo, Rejane Giacomelli Tavares, Sofia Lopes, Tatiana Fontes, L. Monteiro Rodrigues","doi":"10.19277/bbr.18.1.258","DOIUrl":"https://doi.org/10.19277/bbr.18.1.258","url":null,"abstract":"Diet is commonly accepted as a determinant of body composition, especially when related to specific lifestyles. Vegetarian-vegan diets, which involve a reduction or elimination of animal product consumption, are believed to be more “healthy,” facilitating weight control and reducing the incidence and clinical course of different diseases, in particular those related to overweight and obesity. Global reviews and metanalysis on these issues, however, are still insufficient. Our preliminary approach addresses the total body composition differences among vegetarians-vegans and omnivorous individuals. This cross-sectional study involved ten healthy women, five vegetarian-vegan, and five omnivores (mean 28.10 years old). Body composition was assessed using a dual-energy x-ray absorptiometry (DXA Lunar Prodigy Advance - General Electric Healthcare®). Other general and sociodemographic variables were also collected by trained dietitians. Our results have shown that the vegetarian-vegan group had a non-significantly lower volume of all types of body mass (total bone, fat, lean, tissue, and fat-free) evaluated. Additionally, the vegetarian-vegan group presented higher values of visceral adipose tissue and subcutaneous adipose tissue (286.20 and 11138.40 cm3, respectively, p > 0.05) compared to the omnivore group. These differences will be further confirmed in subsequent studies.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90700942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Hereditary Hemochromatosis (Clinical case) 遗传性血色素沉着症(临床一例)

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-01-01 DOI: 10.19277/bbr.18.2.263

Bruno Sousa, Nelson Tavares

引用次数: 0

Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics 胶原提取工艺中正丁醇及罗非鱼皮肤胶原提取物的安全性初步评价

Journal Biomedical and Biopharmaceutical Research Pub Date : 2021-01-01 DOI: 10.19277/bbr.18.1.256

Linda Sánchez-Tuest, Nataly Reátegui-Pinedo, David Salirrosas, Ana Lucía Morocho-Jácome, Fernanda Daud Sarruf, Renata Miliani Martinez, R. Quevedo‐León, Ramiro Fiestas, Carmen Ayala-Jara, André Rolim Baby, Zulita Adriana Prieto

{"title":"Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics","authors":"Linda Sánchez-Tuest, Nataly Reátegui-Pinedo, David Salirrosas, Ana Lucía Morocho-Jácome, Fernanda Daud Sarruf, Renata Miliani Martinez, R. Quevedo‐León, Ramiro Fiestas, Carmen Ayala-Jara, André Rolim Baby, Zulita Adriana Prieto","doi":"10.19277/bbr.18.1.256","DOIUrl":"https://doi.org/10.19277/bbr.18.1.256","url":null,"abstract":"Obtaining new cosmetic ingredients, mainly from sustainable sources, as novel excipients or even active compounds is noteworthy for the cosmetic industry to enhance new innovative dermocosmetics. Thus, it is essential to establish the safety of these new ingredients to avoid adverse events, mainly those associated with clastogenic effects from the chemical compounds used for collagen extraction. In this study, we evaluated solutions of chemical compounds used in the collagen extraction process from tilapia skin (Oreochromis niloticus). The cytotoxic and genotoxic effects of the solutions used in the collagen extraction process were 10.0, 1.0, 0.5, and 0.1% n-butanol. Solutions were evaluated by the Allium test and the comet assay in peripheral white blood cells. The residual water from the final skin wash in the pre-treatment phase and the 0.5% lyophilized collagen extract were also investigated. The absence of cytotoxic and genotoxic activity was demonstrated in the collagen extract, despite the fact that n-butanol showed DNA damage, both in the root cells of Allium cepa and in the white blood cells of human peripheral blood. Therefore, we note the necessity to carry out genotoxicity tests to guarantee the absence of contaminants in the collagen extract for cosmetic purposes","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76035968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Studying the impact of different body positioning, squatting, and unipodal flexion on perfusion in the lower limb – an exploratory approach complemented with optical spectroscopy (TiVi) 研究不同体位、下蹲和单足屈曲对下肢灌注的影响——一种探索性方法与光学光谱(TiVi)相结合

Journal Biomedical and Biopharmaceutical Research Pub Date : 2020-12-01 DOI: 10.19277/BBR.17.2.235

Sergio Nuno, M. Florindo, H. Silva, L. Monteiro Rodrigues

{"title":"Studying the impact of different body positioning, squatting, and unipodal flexion on perfusion in the lower limb – an exploratory approach complemented with optical spectroscopy (TiVi)","authors":"Sergio Nuno, M. Florindo, H. Silva, L. Monteiro Rodrigues","doi":"10.19277/BBR.17.2.235","DOIUrl":"https://doi.org/10.19277/BBR.17.2.235","url":null,"abstract":"Body posture and movement seem to be responsible for multiple variations of microcirculation in the foot, although difficulties associated with measurement during movement have limited their characterization. This pilot study sought to explore a new non-invasive instrument based on polarized light spectroscopy – the TiVi system, under orthostatic and dynamic conditions. Five healthy participants (duly informed, 26.0 ± 6.5 years of age) of both genders were selected. The protocol involved sequential posture changes (orthostatic variation) and dynamic movements (squatting and unipodal flexion). Perfusion variations were evaluated in both feet by laser-Doppler flowmetry (LDF) and polarized spectroscopy (TiVi). Both systems revealed the same type of modification of these flow-related variables. The most pronounced changes were obtained with exercise, especially with squatting, which caused a marked increase in foot perfusion. Less dramatic but in the same direction, the increased perfusion with unipodal flexion was also observed in the contralateral limb. This study confirmed the interest in using the TiVi system in these domains, as well as the appropriateness of this experimental design to look deeper into the impact of lower limb movement on the functional dynamics of the foot.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82489476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Editorial - Vol 17: Number 2 社论-第17卷:第2号

Journal Biomedical and Biopharmaceutical Research Pub Date : 2020-12-01 DOI: 10.19277/bbr.17.2.e

L. Monteiro Rodrigues

{"title":"Editorial - Vol 17: Number 2","authors":"L. Monteiro Rodrigues","doi":"10.19277/bbr.17.2.e","DOIUrl":"https://doi.org/10.19277/bbr.17.2.e","url":null,"abstract":"A year for balance This was our first year of a new (risky) experience, assuming a totally online edition, new editorial procedures, organization, and layout. Happening in a year definitively marked by the extraordinary global crisis caused by this SARS COVID19 changing the definition of “normality” in all aspects of our life. Biomedical and Biopharmaceutical Research journal is no exception. The year of our full open access was simultaneously, the year of many other changes and impacts. Crisis always give space to opportunities, and we did got ours. BBR journal achieved to be more professional and available. Closer to the authors, to the reviewers and editors interacting in a regular way. Stronger in its processes and therefore more rigorous and transparent, in the right track for consolidation. This is no doubt, the most productive editorial year ever in the history of BBR. Our options were clearly accepted by our authors. We read these outcomes as a trust token that we deeply appreciate. Our success is their success. Therefore, we will continue to do more and better for this instrument of scientific culture specially conceived and reasoned in the common language of our Portuguese speaking communities. We stress our independent character, non-profit defined, exclusively based in the science and education, wholeheartedly dedicated to the growth of scientific culture. This is part of our foundation and our compromise for the future. This 2020 closure number includes two articles in the Nutrition and Food Sciences section, six articles in the Biomedical Sciences section and six others in the Biopharmaceutical Sciences section. Three other documents complete this number – the Proceedings Book of the 55th Annual Congress of the Brazilian Society of Physiology which included the 1st Portuguese-Brazilian Physiology Meeting organized by both countries’ (sister) Physiology Societies, the Proceedings Book from the 2020 CBIOS Science Sessions, and the Proceedings Book from the IV CBIOS Seminar 2020.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83348735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anthropometric assessment of children aged between 6 and 14 years from a school in Lisbon 里斯本一所学校6至14岁儿童的人体测量学评估

Journal Biomedical and Biopharmaceutical Research Pub Date : 2020-12-01 DOI: 10.19277/bbr.17.2.237

A. Costa, C. Ferreira-Pêgo, Bruno Sousa

{"title":"Anthropometric assessment of children aged between 6 and 14 years from a school in Lisbon","authors":"A. Costa, C. Ferreira-Pêgo, Bruno Sousa","doi":"10.19277/bbr.17.2.237","DOIUrl":"https://doi.org/10.19277/bbr.17.2.237","url":null,"abstract":"As a global epidemic, obesity is currently a significant public health challenge, especially in children. Childhood obesity is related to short term consequences, but also with an increased risk to develop many comorbidities in adult life, such as cardiovascular diseases, type 2 diabetes, strokes, and others. A cross-sectional study to assess the prevalence of normal weight, pre-obesity and obesity in school-aged children was designed. The final sample size analyzed included 81 participants (47 boys and 34 girls) aged between 6 and 14 years old. Pre-obesity and obesity were determined according to the BMI cut-off points adopted by the IOTF. Although no significant differences were found, the prevalence of pre-obesity and obesity for the total population studied was 16.00% and 6.20%, respectively, with 14.60%, and 4.30% for boys and 17.60% and 8.80% for girls. More girls were pre-obese and obese than boys except at ages 9 and 12. The same age that boys presented cardiometabolic risk associated with a WHtR>0.50. These results emphasize the importance of nutritional status assessment to develop appropriate actions to prevent childhood obesity.","PeriodicalId":14771,"journal":{"name":"Journal Biomedical and Biopharmaceutical Research","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74334321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0