JCR: Journal of Clinical Rheumatology最新文献_第9页

Impact of Methotrexate Discontinuation on the Immunogenicity of COVID-19 Vaccines in Patients With Rheumatoid Arthritis. 停用甲氨蝶呤对类风湿关节炎患者接种 COVID-19 疫苗免疫原性的影响

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-12-01 Epub Date: 2024-11-11 DOI: 10.1097/RHU.0000000000002166

Carolina A Isnardi, Margarita Landi, Leonel Cruces, Pablo Maid, Claudia Calle Montoro, María A Alfaro, Brian M Roldán, Andrea B Gómez Vara, Pamela Giorgis, Roberto A Ezquer, María G Crespo Rocha, Camila R Reyes Gómez, María Á Correa, Osvaldo L Cerda, Marcos G Rosemffet, Virginia Carrizo Abarza, Santiago Catalan Pellet, Miguel Perandones, Cecilia Reimundes, Yesica Longueira, Gabriela Turk, María F Quiroga, Natalia Laufer, María C de la Vega, Gustavo Citera, Guillermo J Pons-Estel, Emilce E Schneeberger

引用次数: 0

Lower Back Pain in Granulomatosis With Polyangiitis: Iliopsoas Muscle Abscess Due to Nontuberculous Mycobacteria. 肉芽肿伴多血管炎患者的下背痛非结核分枝杆菌引起的髂腰肌脓肿。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-12-01 Epub Date: 2024-10-16 DOI: 10.1097/RHU.0000000000002150

Hirotaka Yamamoto, Yoshinori Taniguchi

引用次数: 0

A Remote Behaviorally Designed Intervention to Promote Physical Activity in Patients With Knee Osteoarthritis: Results of a Pilot Randomized Clinical Trial. 促进膝骨关节炎患者体育锻炼的远程行为设计干预：试验性随机临床试验结果。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-12-01 Epub Date: 2024-10-16 DOI: 10.1097/RHU.0000000000002148

Rachel L Gillcrist, Caleigh R Doherty, Marianna Olave, Juliana Bonilla, Bryant R England, Katherine Wysham, Mercedes Quinones, Carla R Scanzello, Alexis Ogdie, Daniel K White, Tuhina Neogi, Joshua F Baker

{"title":"A Remote Behaviorally Designed Intervention to Promote Physical Activity in Patients With Knee Osteoarthritis: Results of a Pilot Randomized Clinical Trial.","authors":"Rachel L Gillcrist, Caleigh R Doherty, Marianna Olave, Juliana Bonilla, Bryant R England, Katherine Wysham, Mercedes Quinones, Carla R Scanzello, Alexis Ogdie, Daniel K White, Tuhina Neogi, Joshua F Baker","doi":"10.1097/RHU.0000000000002148","DOIUrl":"10.1097/RHU.0000000000002148","url":null,"abstract":"Objective: We evaluated a behaviorally designed intervention utilizing gamification and social support to improve physical activity and reduce symptoms in patients with osteoarthritis of the knee (KOA).Methods: Veterans with KOA, aged 40-80 years, were enrolled in this randomized controlled trial. Participants received a Fitbit and completed a 2- to 4-week baseline period. A Web-based platform administered biweekly surveys after randomization and tracked physical activity. Participants selected a daily step goal that was 33%, 40%, or 50% above their baseline. The intervention arm received game playing aspects and a social support partner to advance weekly step performance while the control arm only received weekly updates. The primary outcome was the change in steps per day averaged over 2-week intervals. We used mixed effects regression, adjusting for baseline step count. Secondary outcomes assessed the change in KOOS (Knee Injury and Osteoarthritis Outcome Score) over 32 weeks.Results: Thirty-one participants were included in the final analysis. Most participants were male (90.3%), Black (70.96%), had a mean (SD) age of 60 (13) years, and body mass index of 33.7 (5.9) kg/m 2 . Participants that received the intervention walked a total of 1119 (95% confidence interval: -562, 2799) more steps per day ( p = 0.19). The effect was greatest in the first 6 months (1491 [-272, 3254], p = 0.10). Compared with controls, those that received the intervention had improvement over time in total KOOS (mean 2-week change +0.62 [0.031, 1.20] vs -0.38 [-1.04, 0.28], p = 0.02) and several subscales.Conclusions: This intervention demonstrated promise for promoting greater physical activity and improving symptoms in patients with KOA.","PeriodicalId":14745,"journal":{"name":"JCR: Journal of Clinical Rheumatology","volume":" ","pages":"336-339"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dementia and Emergency Department Use in Older Adults With Systemic Lupus Erythematosus: An Administrative Claims Data Analysis of Medicare Beneficiaries. 老年系统性红斑狼疮患者的痴呆和急诊科使用：医疗保险受益人的行政索赔数据分析。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-11-21 DOI: 10.1097/RHU.0000000000002066

Sarah B Lieber, Musarrat Nahid, Iris Navarro-Millán, Mangala Rajan, Sebastian E Sattui, M Carrington Reid, Lisa A Mandl

{"title":"Dementia and Emergency Department Use in Older Adults With Systemic Lupus Erythematosus: An Administrative Claims Data Analysis of Medicare Beneficiaries.","authors":"Sarah B Lieber, Musarrat Nahid, Iris Navarro-Millán, Mangala Rajan, Sebastian E Sattui, M Carrington Reid, Lisa A Mandl","doi":"10.1097/RHU.0000000000002066","DOIUrl":"https://doi.org/10.1097/RHU.0000000000002066","url":null,"abstract":"Background/objective: Systemic lupus erythematosus (SLE) is associated with increased dementia risk. Whether this association is present among older adults with SLE is unclear. Further, whether individuals with concomitant SLE and dementia are at increased risk of emergency department (ED) use has not been explored. Using US Centers for Medicare & Medicaid Services (2006-2015) administrative claims data, we (1) quantified long-term all-cause dementia prevalence in adults with SLE ≥65 years of age and (2) determined whether dementia duration is associated with risk of ED visits in a cohort of older adults with SLE relative to comparators.Methods: Medicare beneficiaries ≥65 years of age with SLE and age- and sex-matched comparators (1:4) with osteoarthritis were identified at baseline (2006). Dementia was considered a time-varying exposure, updated annually. Mixed-effect Poisson regression was used to estimate the effect of dementia duration on risk of multiple ED visits for the study period (January 2006 to September 2015), adjusting for relevant covariates.Results: Baseline dementia prevalence was similar among beneficiaries with SLE (n = 1338 [4.6%]) and non-systemic rheumatic disease (non-SRD) comparators (n = 5352 [5.7%]). Stronger association between dementia duration and ED use was observed in older adults with SLE, including after adjustment for covariates (SLE: incidence rate ratio, 1.10; 95% confidence interval, 1.07-1.13; non-SRD: incidence rate ratio, 1.05; 95% confidence interval, 1.03-1.06).Conclusions: Although dementia prevalence was similar between older adults with SLE and non-SRD comparators, dementia duration had a greater impact on ED use in aging adults with SLE versus non-SRD comparators. Geriatric assessment may be especially important in older adults with SLE.","PeriodicalId":14745,"journal":{"name":"JCR: Journal of Clinical Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproductive Health in Scleroderma, Vasculitis, and Sjögren Syndrome. 硬皮病、血管炎和斯约格伦综合症患者的生殖健康。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-10-01 DOI: 10.1097/RHU.0000000000002128

Francesca Crisafulli, Maria Grazia Lazzaroni, Cecilia Nalli, Rossana Orabona, Franco Franceschini, Angela Tincani

引用次数: 0

Lumbar Epidural Corticosteroid Injection-Induced Epidural Lipomatosis. 腰部硬膜外皮质类固醇注射引起的硬膜外脂肪瘤病。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-10-01 Epub Date: 2024-08-28 DOI: 10.1097/RHU.0000000000002126

Georges Hayek, Maud Creze

引用次数: 0

Treatment Patterns for End-stage Kidney Failure in Patients with Systemic Lupus Erythematous: Erratum. 系统性红斑狼疮患者终末期肾衰竭的治疗模式：勘误。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-10-01 DOI: 10.1097/RHU.0000000000002153

引用次数: 0

Refractory Pneumonitis in Rheumatoid Arthritis: Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma. 类风湿性关节炎的难治性肺炎：肺粘膜相关淋巴组织淋巴瘤。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-10-01 Epub Date: 2024-08-28 DOI: 10.1097/RHU.0000000000002129

Hirotaka Yamamoto, Yoshinori Taniguchi

引用次数: 0

Safety of Medications Used to Treat Autoimmune Rheumatic Diseases During Pregnancy and Lactation. 孕期和哺乳期治疗自身免疫性风湿病药物的安全性。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-10-01 DOI: 10.1097/RHU.0000000000002123

Caroline H Siegel, Lisa R Sammaritano

{"title":"Safety of Medications Used to Treat Autoimmune Rheumatic Diseases During Pregnancy and Lactation.","authors":"Caroline H Siegel, Lisa R Sammaritano","doi":"10.1097/RHU.0000000000002123","DOIUrl":"https://doi.org/10.1097/RHU.0000000000002123","url":null,"abstract":"Abstract: Autoimmune rheumatic diseases (ARDs) often affect women during their reproductive years, and early studies of pregnancy in these patients reported high rates of adverse outcomes. Continuation or initiation of safe and effective medications in the preconception period is beneficial for maintaining or achieving disease quiescence throughout pregnancy thereby improving both maternal and pregnancy outcomes. The European Alliance of Associations for Rheumatology, the American College of Rheumatology, and the British Society for Rheumatology have published recommendations and guidelines regarding management of ARDs during pregnancy. The American College of Obstetricians and Gynecologists and the American Gastroenterological Association have also provided guidance statements with relevant recommendations. This review provides an overview of available recommendations for medication use in ARD pregnancy, with discussion of safety considerations for maternal and fetal well-being. Medications considered compatible with pregnancy include hydroxychloroquine, sulfasalazine, azathioprine, cyclosporine, tacrolimus, and TNF inhibitors. Methotrexate, mycophenolate, leflunomide, and cyclophosphamide should be avoided before and during pregnancy. Other medications, most of them newer, are largely discouraged for use in pregnancy due to inadequate data or concerns for neonatal immunosuppression, including non-TNF biologics and small molecule therapies. Further investigation is needed regarding effects of non-TNF biologics, biosimilars, and small molecules in pregnancy. Important efforts for the future will include improved methodologies to gather critical safety data, with consideration of inclusion of pregnant women in clinical trials, a complex and controversial issue. Long-term information on outcomes in offspring of treated women is lacking for many of these medications.","PeriodicalId":14745,"journal":{"name":"JCR: Journal of Clinical Rheumatology","volume":"30 7S Suppl 1","pages":"S25-S33"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous IgG4-Related Disease. 皮肤 IgG4 相关疾病。

IF 2.4 4区医学

JCR: Journal of Clinical Rheumatology Pub Date : 2024-10-01 Epub Date: 2024-07-16 DOI: 10.1097/RHU.0000000000002113

Hirotaka Yamamoto, Yoshinori Taniguchi

引用次数: 0