Journal de pharmacie de Belgique最新文献_第10页

[Critical evaluation of interaction screening software available in pharmacies]. [对药店可用的相互作用筛选软件的关键评价]。

Journal de pharmacie de Belgique Pub Date : 2012-12-01

S Schillemans, H De Loof, G R Y De Meyer

{"title":"[Critical evaluation of interaction screening software available in pharmacies].","authors":"S Schillemans, H De Loof, G R Y De Meyer","doi":"","DOIUrl":"","url":null,"abstract":"Due to the increasing complexity of medication regimens it is not always easy for the pharmacist to quickly and effectively screen the drug use of a particular patient for interactions. By means of a survey and a comparison, the advantages and disadvantages of the most common software packages available in Flanders were analysed. Major stumbling blocks of the currently available software are the high number of false positive signals, the absence of a history regarding the management of interactions, the lack of timely updates of the database and the absence of clear guidelines for the management of an interaction. Based on this research, we make the following recommendations: (1) signal fatigue should be reduced by interaction screening based on the duration of therapy in addition to the ability to suppress signals, (2) a log, coupled with the prescription-register, should be implemented, (3) software companies should help pharmacists more in configuring software preferences and provide them with better information bout the available options, (4) the underlying databases must be updated more quickly. (5) OTC medications, especially in the context of polypharmacy, should be registered in the patient record by the pharmacist, (6) note that food supplements are not included in the interaction screening software, unlike registered medication. (7) the knowledge of pharmacists regarding interactions should be maintained and improved.","PeriodicalId":14736,"journal":{"name":"Journal de pharmacie de Belgique","volume":" 4","pages":"4-13"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31188426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Does 5-methyltetrahydrofolate offer any advantage over folic acid?]. [5-甲基四氢叶酸是否比叶酸更有优势?]

Journal de pharmacie de Belgique Pub Date : 2012-12-01

L Leemans

{"title":"[Does 5-methyltetrahydrofolate offer any advantage over folic acid?].","authors":"L Leemans","doi":"","DOIUrl":"","url":null,"abstract":"Almost half of the women do not follow the guidelines around folate suppletion before and during pregnancy, despite the proven benefit in the prevention of neural tube defects, miscarriages and premature births. The Belgian Superior Health Council recommends a minimum of 400 micrograms of folic acid or folate suppletion per day from 4 weeks before conception to 8 weeks thereafter. Many studies point to the importance of a wider intake period, more particularly at least 3 months before conception and throughout pregnancy and lactation. In high-risk women 4 mg is recommended until after the first 3 months of pregnancy. Afterwards the usual dose of 400 micrograms is sufficient. About half of the European population appears to have a gene mutation on the gene coding for the production of methylenetetrahydrofolate reductase, the enzyme that is involved in the formation of 5-methyltetrahydrofolate, which is, in his turn, responsible for the conversion of the toxic homocysteine in methionine. Women with such a gene polymorphism have a significantly higher risk to have a miscarriage or a baby with neural tube defects. For this reason, a search for an alternative form of synthetic folic acid supplement \"pteroylmonoglutamic acid (PMG)\" was conducted, particularly the calcium salt of 5-methyltetrahydrofolate (Metafolin). This offers the possibility to deliver the reduced folate immediately, which no longer needs to be converted by the reductase enzyme. Furthermore, this avoids free PMG in the circulation, lowers the risk for drug interactions and a vitamin B2 deficiency will not be masked. Despite clear guidelines regarding dietary supplements before and during pregnancy, their implementation is poor. Not only gynecologists but also GPs and pharmacists, should make more efforts to provide women of childbearing age with personal information. Especially risk groups such as adolescents, low-skilled or less well-off women and immigrants deserve special attention.","PeriodicalId":14736,"journal":{"name":"Journal de pharmacie de Belgique","volume":" 4","pages":"16-22"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31188431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Approach of dry cough in community pharmacy]. [社区药房干咳治疗方法]。

Journal de pharmacie de Belgique Pub Date : 2012-12-01

N Duquet

引用次数: 0

[Racecadotril (Tiorfix), oral]. [口服消旋卡多曲]。

Journal de pharmacie de Belgique Pub Date : 2012-12-01

Daniel Duh, Indiana Tanret

引用次数: 0

[Managing drug interactions at the pharmacy counter. The case of NSAIDs]. 在药房柜台管理药物相互作用。非甾体抗炎药的案例]。

Journal de pharmacie de Belgique Pub Date : 2012-09-01

N Duquet

引用次数: 0

[Role of the community pharmacist in the management of drug related problems in home care patients]. [社区药师在家庭护理患者药物相关问题管理中的作用]。

Journal de pharmacie de Belgique Pub Date : 2012-09-01

M Van de Putte, S Appels, T Boone, S Collienne, T Daems, J De Lepeleire, V Foulon

引用次数: 0

Basic epidemiology of opiate misuse substitution treatment in Belgium. 比利时阿片类药物滥用替代治疗的基本流行病学。

Journal de pharmacie de Belgique Pub Date : 2012-09-01

Y Ledoux

{"title":"Basic epidemiology of opiate misuse substitution treatment in Belgium.","authors":"Y Ledoux","doi":"","DOIUrl":"","url":null,"abstract":"The Substitution Treatment National Registry provided from mid 2006 till mid 2009 an exhaustive documentation on all patients being prescribed methadone or buprenorphine in Belgium. This endeavour was possible through cooperation of all community pharmacies and their representative organizations was supported at the time by the former Health federal minister. The Liberal belgian opiate medical substitution process authorizes untill now de facto any doctor to prescribe methadone and pharmacists are supported to dispense it. Results show the regional, provincial and county numbers of professionals and patients prevalence in the population. Nationwide, n = 16974 patients (prevalence for population aged 20-64: 26/10000) have been offered substitution from mid 2008 till mid 2009, n = 3390 pharmacies 164,4% of all pharmacies) and n = 2937 MDs (16,75% of all MDs) have been involved. Subutex or Suboxone have been dispensed to 11,1% of substitution patients with 7,4% receiving only buprenorphine on a yearly basis. Number of substitution patients by MD and prevalence by gender, age group and region are presented. Important variations are observed locally, possibly mirroring heroin addiction due to widespread access to substitution treatment. Younger patients are more prevalent in semi rural or border areas. The exhaustivity of available data enables also to observe patients quitting substitution altogether and a strong difference of maintenance rate is observed favoring methadone over buprenorphine.","PeriodicalId":14736,"journal":{"name":"Journal de pharmacie de Belgique","volume":" 3","pages":"30-9"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31448865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The different intake modalities of oral antibiotics]. [口服抗生素的不同摄入方式]。

Journal de pharmacie de Belgique Pub Date : 2012-09-01

J Maesschalck

引用次数: 0

[Glusosamine preparations in the community pharmacy -- introduction]. 【社区药房的氨基葡萄糖制剂——介绍】。

Journal de pharmacie de Belgique Pub Date : 2012-06-01

J Saevels

引用次数: 0

[Self-medication of regular headache: a community pharmacy-based survey in Belgium]. [自我治疗经常性头痛:比利时社区药房调查]。

Journal de pharmacie de Belgique Pub Date : 2012-06-01

E Mehuys, K Paemeleire, T Van Hees, T Christiaens, L Van Bortel, I Van Tongelen, G Philippe, M L Prévôt, B Evrard, M Piette, L De Bolle, J-P Remon, K Boussery

{"title":"[Self-medication of regular headache: a community pharmacy-based survey in Belgium].","authors":"E Mehuys, K Paemeleire, T Van Hees, T Christiaens, L Van Bortel, I Van Tongelen, G Philippe, M L Prévôt, B Evrard, M Piette, L De Bolle, J-P Remon, K Boussery","doi":"","DOIUrl":"","url":null,"abstract":"Aim: This observational community pharmacy-based study aimed to investigate headache characteristics and medication use of persons with regular headache presenting for self-medication.Methods: Participants (n=1205) completed ii) a questionnaire to assess current headache medication and previous physician diagnosis, (ii) the ID Migraine Screener [ID-M] and (iii) the MIDAS questionnaire.Results: Forty-four % of the study population (n=528) did not have a physician diagnosis of their headache, and 225 of them (225/528, 42.6%) were found to be ID-M positive. The most commonly used acute headache drugs were paracetamol (used by 62% of the study population), NSAIDs (39%) and combination analgesics (36%). Only 12% of patients physician-diagnosed with migraine used prophylactic migraine medication, and 25% used triptans. About 24% of our sample (n=292) chronically overused acute medication, which was combination analgesic overuse (n=166), simple analgesic overuse (n=130), triptan overuse (n=19), ergot overuse (n=6) and opioid overuse (n=51). Only 14.5% was ever advised to limit intake frequency of acute headache treatments.Conclusions: This study identified underdiagnosis of migraine, low use of migraine prophylaxis and triptans, and high prevalence of medication overuse among subjects seeking self-medication for regular headache. Community pharmacists have a strategic position in education and referral of these self-medicating headache patients.","PeriodicalId":14736,"journal":{"name":"Journal de pharmacie de Belgique","volume":" 2","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30907098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0