JAMA dermatology最新文献

筛选
英文 中文
Skin Inflammation, Systemic Inflammation, and Cardiovascular Disease in Psoriasis. 牛皮癣的皮肤炎症、系统炎症和心血管疾病。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.4433
Axel Svedbom, Lotus Mallbris, Álvaro González-Cantero, Martin Playford, Colin Wu, Nehal N Mehta, Mona Ståhle
{"title":"Skin Inflammation, Systemic Inflammation, and Cardiovascular Disease in Psoriasis.","authors":"Axel Svedbom, Lotus Mallbris, Álvaro González-Cantero, Martin Playford, Colin Wu, Nehal N Mehta, Mona Ståhle","doi":"10.1001/jamadermatol.2024.4433","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4433","url":null,"abstract":"<p><strong>Importance: </strong>Psoriasis is associated with increased cardiovascular risk, but the underlying pathogenic mechanisms remain unclear. Elucidating these mechanisms can help develop treatment strategies and enhance understanding of the link between peripheral inflammation, such as psoriatic skin lesions, and cardiovascular disease (CVD).</p><p><strong>Objective: </strong>To explore whether systemic inflammation is a mediator of the association between psoriasis skin disease severity and CVD.</p><p><strong>Design, setting, and participants: </strong>This cohort study used data from cross-sectional study (Psoriasis Atherosclerosis and Cardiometabolic Disease Initiative [PACI]), which enrolled patients from January 2013 to February 2022, and an inception cohort study (Stockholm Psoriasis Cohort [SPC]), which enrolled patients from January 2000 to December 2005. The PACI enrolled consecutive patients referred by dermatologists in Maryland, and the SPC enrolled consecutive patients referred from a wide range of practices in Sweden. Patients with prevalent psoriasis from the PACI and patients with incident psoriasis from the SPC were included. Data were analyzed from October 2023 to January 2024.</p><p><strong>Exposures: </strong>Psoriasis skin disease severity was measured using the Psoriasis Area and Severity Index (PASI), and systemic inflammation was measured using glycan biomarker of N-acetyl side chains of acute-phase proteins (GlycA). Mediation analysis was performed by evaluating the associations between exposure, mediator, and outcome in patients with first-tertile and third-tertile PASI scores when GlycA level was set at the level observed in patients with first-tertile PASI.</p><p><strong>Main outcomes and measures: </strong>Noncalcified coronary burden (NCB) measured using coronary computed tomography angiography in the PACI and hospitalization for CVD or cardiovascular death in the SPC.</p><p><strong>Results: </strong>Of 260 eligible patients from the PACI, 162 (62.3%) were male, and the median (IQR) age was 51 (41-60) years; of 509 eligible patients from the SPC, 237 (46.6%) were male, and the median (IQR) age was 43 (30-57) years. In both studies, PASI was associated with GlycA level and CVD, and GlycA level was associated with CVD. The direct and indirect (through GlycA) effects of PASI on NCB were estimated at 0.94 (95% CI, 0.26-1.74) and 0.19 (95% CI, 0.02-0.47), respectively. The odds ratios for the direct and indirect effects of PASI on cardiovascular events were estimated at 1.23 (95% CI, 0.70-1.92) and 1.16 (95% CI, 1.04-1.42), respectively.</p><p><strong>Conclusions and relevance: </strong>In this study, skin disease severity measured using PASI was associated with systemic inflammation, and both PASI and systemic inflammation, measured using GlycA levels, were associated with CVD. The association between PASI and CVD may be mediated by systemic inflammation.</p>","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salt and Atopic Dermatitis. 盐与特应性皮炎
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.4917
Yi-Cheng Lin, Chia-Hao Hsu
{"title":"Salt and Atopic Dermatitis.","authors":"Yi-Cheng Lin, Chia-Hao Hsu","doi":"10.1001/jamadermatol.2024.4917","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4917","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Annular Eroded Plaque With Honey-Colored Crusting On Scrotum. 阴囊上有环状蚀斑,并伴有蜜色结痂。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.4424
Toan S Bui, Jonathan J Lee
{"title":"Annular Eroded Plaque With Honey-Colored Crusting On Scrotum.","authors":"Toan S Bui, Jonathan J Lee","doi":"10.1001/jamadermatol.2024.4424","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4424","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Error in Figure 2. 图 2 中的错误。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.5294
{"title":"Error in Figure 2.","authors":"","doi":"10.1001/jamadermatol.2024.5294","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.5294","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salt and Atopic Dermatitis. 盐与特应性皮炎
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.4914
Ian A Myles, Jeffrey B Kopp
{"title":"Salt and Atopic Dermatitis.","authors":"Ian A Myles, Jeffrey B Kopp","doi":"10.1001/jamadermatol.2024.4914","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4914","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salt and Atopic Dermatitis-Reply. 盐与特应性皮炎-回复。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.4911
Brenda M Chiang, Morgan Ye, Katrina Abuabara
{"title":"Salt and Atopic Dermatitis-Reply.","authors":"Brenda M Chiang, Morgan Ye, Katrina Abuabara","doi":"10.1001/jamadermatol.2024.4911","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4911","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss: An International Modified Delphi Consensus Statement. 脱发患者开始使用小剂量米诺地尔口服液:国际修正德尔菲共识声明。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-20 DOI: 10.1001/jamadermatol.2024.4593
Yagiz Matthew Akiska, Paradi Mirmirani, Ingrid Roseborough, Erin Mathes, Tina Bhutani, Andrew Ambrosy, Crystal Aguh, Wilma Bergfeld, Valerie D Callender, Leslie Castelo-Soccio, George Cotsarelis, Brittany Gareth Craiglow, Nisha S Desai, Isabella Doche, Bruna Duque-Estrada, Dirk M Elston, Carolyn Goh, Lynne J Goldberg, Ramon Grimalt, Ali Jabbari, Victoria Jolliffe, Brett A King, Charlotte LaSenna, Yolanda Lenzy, Jenna C Lester, Nino Lortkipanidze, Kristen I Lo Sicco, Amy McMichael, Nekma Meah, Natasha Mesinkovska, Mariya Miteva, Arash Mostaghimi, Yuliya Ovcharenko, Melissa Piliang, Bianca Maria Piraccini, Adriana Rakowska, Kimberly S Salkey, Adriana Schmidt, Jerry Shapiro, Cathryn Sibbald, Rodney Sinclair, Poonkiat Suchonwanit, Susan Taylor, Antonella Tosti, Sergio Vañó-Galván, Dmitri Robert Wall, Jennifer M Fu
{"title":"Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss: An International Modified Delphi Consensus Statement.","authors":"Yagiz Matthew Akiska, Paradi Mirmirani, Ingrid Roseborough, Erin Mathes, Tina Bhutani, Andrew Ambrosy, Crystal Aguh, Wilma Bergfeld, Valerie D Callender, Leslie Castelo-Soccio, George Cotsarelis, Brittany Gareth Craiglow, Nisha S Desai, Isabella Doche, Bruna Duque-Estrada, Dirk M Elston, Carolyn Goh, Lynne J Goldberg, Ramon Grimalt, Ali Jabbari, Victoria Jolliffe, Brett A King, Charlotte LaSenna, Yolanda Lenzy, Jenna C Lester, Nino Lortkipanidze, Kristen I Lo Sicco, Amy McMichael, Nekma Meah, Natasha Mesinkovska, Mariya Miteva, Arash Mostaghimi, Yuliya Ovcharenko, Melissa Piliang, Bianca Maria Piraccini, Adriana Rakowska, Kimberly S Salkey, Adriana Schmidt, Jerry Shapiro, Cathryn Sibbald, Rodney Sinclair, Poonkiat Suchonwanit, Susan Taylor, Antonella Tosti, Sergio Vañó-Galván, Dmitri Robert Wall, Jennifer M Fu","doi":"10.1001/jamadermatol.2024.4593","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4593","url":null,"abstract":"<p><strong>Importance: </strong>The results of small studies suggest that off-label use of low-dose oral minoxidil (LDOM) may be safe and effective for patients with hair loss, but larger trials and standardized guidelines are lacking.</p><p><strong>Objective: </strong>To create an expert consensus statement for LDOM prescribing for patients with hair loss.</p><p><strong>Evidence review: </strong>The current literature on the pharmacological properties, adverse effect profile, and use of LDOM for patients with hair loss was reviewed. Topics of interest were identified, and a modified Delphi consensus process was created. A total of 43 hair loss specialist dermatologists from 12 countries participated in a modified Delphi process. Consensus was reached if at least 70% agreed or strongly agreed on a 5-point Likert scale.</p><p><strong>Findings: </strong>Over 4 survey rounds, 180 items in the first round, 121 items in the second round, 16 items in the third round, and 11 items in the fourth round were considered and revised. A total of 76 items achieved consensus including diagnoses for which LDOM may provide direct or supportive benefit, indications for LDOM compared to topical minoxidil, dosing for adults (18 years and older) and adolescents (aged 12 to 17 years), contraindications, precautions, baseline evaluation, monitoring, adjunctive therapy, and specialty consultation. Pediatric use and dosing items for children younger than 12 years, and LDOM titration protocols fell short of consensus.</p><p><strong>Conclusions and relevance: </strong>This international expert consensus statement regarding the off-label prescribing of LDOM for patients with hair loss can help guide clinical practice until more data emerge. Hair loss experts with experience treating pediatric patients were underrepresented on this expert panel. Future research should investigate best practices for LDOM use in pediatric patients. Other critical topics for further investigation include the comparative efficacy of topical minoxidil vs oral minoxidil, the safety of oral minoxidil for patients with a history of allergic contact dermatitis to topical minoxidil, the long-term safety of LDOM, and the use of other off-label forms of minoxidil, such as compounded formulations of oral minoxidil and sublingual minoxidil. As additional evidence-based data emerge, these recommendations should be updated.</p>","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lowell A. Goldsmith, MD, MPH, 1938-2024-A Personal Remembrance From 3 Friends. 洛厄尔-戈德史密斯(Lowell A. Goldsmith),医学博士,公共卫生硕士,1938-2024-三位好友的个人纪念。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-16 DOI: 10.1001/jamadermatol.2024.5359
Ervin Epstein, Gerald S Lazarus, Luis A Diaz
{"title":"Lowell A. Goldsmith, MD, MPH, 1938-2024-A Personal Remembrance From 3 Friends.","authors":"Ervin Epstein, Gerald S Lazarus, Luis A Diaz","doi":"10.1001/jamadermatol.2024.5359","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.5359","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Doxycycline Postexposure Prophylaxis (DoxyPEP) for Bacterial STI Prevention. 用于预防细菌性性传播感染的强力霉素暴露后预防疗法(DoxyPEP)。
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-13 DOI: 10.1001/jamadermatol.2024.4567
Muhammad H Junejo, Julia L Marcus, Kenneth A Katz
{"title":"Doxycycline Postexposure Prophylaxis (DoxyPEP) for Bacterial STI Prevention.","authors":"Muhammad H Junejo, Julia L Marcus, Kenneth A Katz","doi":"10.1001/jamadermatol.2024.4567","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4567","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spesolimab Response in a Patient With Steroid-Resistant Sweet Syndrome. 斯派索利单抗对一名类固醇耐药甜美综合征患者的反应
IF 11.5 1区 医学
JAMA dermatology Pub Date : 2024-11-13 DOI: 10.1001/jamadermatol.2024.4342
Zhiyu Pang, Chao Wu, Jie Liu, Yuehua Liu, Hongzhong Jin
{"title":"Spesolimab Response in a Patient With Steroid-Resistant Sweet Syndrome.","authors":"Zhiyu Pang, Chao Wu, Jie Liu, Yuehua Liu, Hongzhong Jin","doi":"10.1001/jamadermatol.2024.4342","DOIUrl":"https://doi.org/10.1001/jamadermatol.2024.4342","url":null,"abstract":"","PeriodicalId":14734,"journal":{"name":"JAMA dermatology","volume":" ","pages":""},"PeriodicalIF":11.5,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信