Jorjani Biomedicine Journal最新文献

{"title":"The evaluation of mandibular canal visibility on cone beam computed tomography (CBCT) images: A cross-sectional study","authors":"S. H. Razavi, Soudeh Berahmand, Khalil Sarikhani Khorami, Motahareh Kaboodsaz Yazdi, N. Namiranian","doi":"10.29252/jorjanibiomedj.7.3.56","DOIUrl":"https://doi.org/10.29252/jorjanibiomedj.7.3.56","url":null,"abstract":"soudeh.b92@gmail.com Abstract Background and objectives: An effective factor in choosing the correct place for the dental implant and performing surgical procedures in the posterior regions of mandible is the position of the mandibular canal. Failure to consider this important landmark will damage the inferior alveolar nerve. Considering the widespread use of implants and the precision of the images obtained from CBCT. The aim of this study was to evaluate the rate of visibility of mandibular canal by CBCT in order to prevent damage to the inferior alveolar nerves and arteries. Methods: In this study, 90 archived CBCT images of patients from a private center of oral and maxillofacial radiology in Yazd that was taken by technician was evaluated during 2012-2019. The visibility of the mandibular canal in reconstructed panoramic images of CBCT was assessed by a dentistry student trained by the maxillofacial radiologist in five areas in different thicknesses on each side. Data were analyzed using SPSS 17 software. Chi-square, and correlation coefficient were done. Results: In total, in 53.38% of CBCT images both borders of mandibular canal were visible, in 17.95%, only one border was visible (difficult observation) and in 28.7% of cases, lack of visibility of mandibular canal was reported. There was no significant difference between sex, age, side and thickness in mandibular canal visibility (P >0.05). Conclusion: In more than half of CBCT images, both borders were clearly visible in both right and left sides; therefore we can conclude that CBCT is a useful tool for the observation of mandibular canal before surgeries.","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89737411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumorigenicity of Esophageal Cancer Stem Cells (ECSCs) in nude mouse xenograft model","authors":"Ayyoob Khosravi, Fariba Kokabi, R. Behzadi, J. Asadi","doi":"10.29252/jorjanibiomedj.7.3.4","DOIUrl":"https://doi.org/10.29252/jorjanibiomedj.7.3.4","url":null,"abstract":"Jahanbakhsh Asadi, Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran dr.asadi@goums.ac.ir Abstract Background and objectives: Modeling cancer in vivo is a very important tool to investigate cancer pathogenesis and molecular mechanisms involved in cancer progression. Laboratory mice are the most common animal used for rebuilding human cancer in vivo. Cancer stem cells (CSCs) are the main reason of failure in cancer therapy because of tumor relapse and metastasis. Isolation of cancer stem cells helps us to study their function and behavior. In the current study we separate cancer stem-like cells using sphere formation assay then investigate their tumorigenicity in xenograft tumor model. Methods: YM1 cancer cells were cultured in serum-free media (SFM) in low adherent culture dishes for enrichment of cancer stem cells. The resulting spheres containing cancer stem-like cells were dissociated into single cells and were injected into the dorsal flank of B6 nude mice. Results: A few days after injection, subcutaneous tumors formed. The growth curves of the resulting tumors were plotted using their weekly recorded lengths. The tumors' volume and weight were measured. The size of resulting tumors was appropriate to the number of cells injected. Pathological analysis confirmed esophageal origin of the resulting tumors. Conclusion: Using laboratory mice models is a practical modeling system that provides us investigation of human tumors pathogenesis in vivo.","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84296868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National Food and Nutrition Security System (SAMAT), A Tool for Identifying and Monitoring Food Insecurity in the Country","authors":"M. Gholami, Majid Najafzadeh, N. Behnampour, Z. Abdollahi, F. S. Ghotbabadi, F. Lashkarboluki, M. Honarvar","doi":"10.29252/jorjanibiomedj.7.3.24","DOIUrl":"https://doi.org/10.29252/jorjanibiomedj.7.3.24","url":null,"abstract":"Mohammad Reza Honarvar, Health Management and Social Development research Center, Golestan University of Medical Sciences, Gorgan, Iran mrhonarvar@goums.ac.ir Abstract Background and objectives: Iran was reported in the high-risk group of World Food Security Map in 2008 .Identifying food insecurity is first step for executing interventions. Measuring household food security is its cornerstone. SAMAT System was designed to provide a variety of GIS-based reports to policy makers and managers in the field of food security. Methods: SAMAT system was developed by a team working with various specialties. The system was analyzed using Rational Unified Process methodology and after optimization and normalization process, centralized database was formed. SQL Server 2014 software was used for its implementation. SharpMap open source engine was used to render spatial data and display maps on the web, and many parts of the engine were coded specifically to meet different organizational needs. The system was designed using the WEB GIS engine. Results: SAMAT system was executed in nine provinces of the country in different periods. SAMAT dashboard provides a variety of information for executive managers. Based on demographic data, the state of food insecurity can be identified at different levels from city to village, in a variety of graphs. A spectrum from the urban distribution to the local distribution of food insecurity can be identified on the GIS map. Zooming in on different areas can help to identify more food insecure neighborhoods within the village or town, thus giving managers the priority of food insecurity interventions at the neighborhood or village level. One can view household characteristics and the results of questionnaire information. Conclusion: AMAT system can be useful for managing food security at the national, provincial, city and even rural or urban levels. we recommend periodically prioritizing points, Identifying the provinces and re-evaluating the effectiveness of interventions through the SAMAT-based system after comprehensive implementation of food insecurity reduction","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73386165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, dimension and location of retromolar canal on cone beam computed tomography: An Analytical cross sectional study","authors":"Khalil Sarikhani Khorami, F. Ardakani, Y. Safi, Motahare Baghestani","doi":"10.29252/JORJANIBIOMEDJ.7.3.68","DOIUrl":"https://doi.org/10.29252/JORJANIBIOMEDJ.7.3.68","url":null,"abstract":"baghestani.motahare@ yahoo.com Abstract Background and objectives: The retromolar canal is an anatomical variant that needs consideration in local anesthesia and surgical procedures involving the retromolar area. Complications such as local anesthetic insufficiency, a sensory deficit, hemorrhage and traumatic neuroma may arise in the absence of recognition of these variants. The aim of this study is to determine the prevalence and course of retromolar canal in the Iranian population. Methods: This study is a descriptive cross sectional study. The cross sectional sagittal and three dimensional images from volumetric CBCT. data of 270 patients were reconstructed using on demand imaging analysis software. Retromolar canals were classified into two types according to the courses. The width and location (distance from the third molar) of retromolar canals were evaluated. Results were analyzed with SPSS 20 software and were assessed using the t_test and chi_square test. Results: Retromolar canal was observed in 9/25 % of patients. The mean width of the retromolar foramen was 1/43 mm, and the mean distance from anterior border of retromolar foramen to the distal CEJ of the second molar was 13/33 mm. Conclusion: The prevalence of retromolar canals in the Iranian population was lower than that was reported in previous studies. It can be observed in 9/25 % of Iranian patients. Damage to the retromolar canal may be unavoidable during surgical procedures may result in paresthesia, excessive bleeding, postoperative hematoma, or traumatic neuroma. Therefore, the clinician must pay particular attention to the identification of a retromolar canal by preoperative radiographic examination and additional CBCT scanning is recommended.","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91067799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Interferon-gamma Gene Polymorphism (+874 A/T) and Oral Lichen planus susceptibility: Systematic Review and Meta-Analysis","authors":"P. Motahari, F. P. Azar, Parisa Rasouly","doi":"10.29252/jorjanibiomedj.7.3.45","DOIUrl":"https://doi.org/10.29252/jorjanibiomedj.7.3.45","url":null,"abstract":"paria@motahari.com Abstract Background and objectives: Most studies have identified interferon-gamma (IFN-γ) as a key role in the pathogenesis of oral lichen planus (OLP). Recent studies have also shown a link between IFN-γ (+874 A/T) gene polymorphism and OLP. The purpose of the present meta-analysis is to investigate the relationship between IFN-γ (+874 A/T) gene polymorphism and susceptibility to OLP. Methods: A systematic search of resources to investigate the association between IFN-γ and OLP from Google scholar, PubMed, Embase, Cochrane, Scopus, Proquest, Ovid and Web of science (from 2000 to April 2019) completed. Two individuals independently assessed the quality of the articles. Endnote X5 resource management software was used to organize, study titles and abstracts as well as identify duplicates. A random effect model was also used to perform the meta-analysis. Results: Four IFN-γ (+874 A/T) polymorphism studies with 297 patients in the case group and 621 healthy controls in the 4 different countries were included. After metaanalysis, a significant association was found between IFN-γ polymorphism (+874 A/T) and OLP. (T vs A: odds ratio (OR) = 1.62; 95% CI = 1.28-2.04; TT vs AA: OR = 2.67; 95% CI = 1.64.45; AT vs AA: OR = 1.56; 95% CI = 1.64.45; TT vs AT + AA: OR = 1.73; 95% CI = 1.13-2.64; AT + TT vs AA: OR = 1.75; 95% CI = 1.28-2.43) Conclusion: Based on this meta-analysis, there was a positive relationship between IFNγ (+874 A/T) gene polymorphism and the risk of OLP. The findings showed that increasing TT genotypes significantly increased susceptibility to OLP in comparison with other genotypes.","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76590021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Expression of miR-202-3p in Patients with Relapsing-Remitting Multiple Sclerosis","authors":"Majid Amini Khorasgani, Parisa Mohammady Nejad, Mohammad Mehdi Moghani Bashi","doi":"10.29252/jorjanibiomedj.6.4.8","DOIUrl":"https://doi.org/10.29252/jorjanibiomedj.6.4.8","url":null,"abstract":"","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74520567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Current and Desirable Status of Iran's Basic Health Insurance","authors":"Roohollah Gholikhani, F. Azar, M. Kabir, M. M. Tadayon","doi":"10.29252/JORJANIBIOMEDJ.6.4.53","DOIUrl":"https://doi.org/10.29252/JORJANIBIOMEDJ.6.4.53","url":null,"abstract":"1. Department of public law, Faculty of law (campus), Tehran University, Tehran, Iran 2. Department of Health Services, School of Public Health, Iran University of Medical Science, Tehran, Iran 3. Department of Family and Community Medicine, School of Medicine Golestan University of Medical Sciences, Gorgan, Iran. 4. National Center for Health insurance Research. (NCHIR). Iran. Health Insurance Organization (IHIO)","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86457248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti -Bacterial Activity of Punica granatum Flower Extract against Several Gram-Negative and Positive Bacteria","authors":"Ali Ahmadi, N. Soleimani, parham abedini","doi":"10.29252/JORJANIBIOMEDJ.6.4.1","DOIUrl":"https://doi.org/10.29252/JORJANIBIOMEDJ.6.4.1","url":null,"abstract":"Antibiotic resistance is considered as one of the world's most pressing public health problems. Almost every type of bacteria has become stronger and less responsive to antibiotic treatment (1, 2). Thesis antibioticresistant bacteria can quickly spread to family members, schoolmates, and co-workers thus threatening the community with a new strain of infectious disease that is more difficult to cure and more expensive to treat. For this reason, antibiotic resistance is among the top concerns of the Center for Disease Control Article Type: Original Article","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78218908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions","authors":"Abolfazl Jafari-Sales, P. Bolouri","doi":"10.29252/JORJANIBIOMEDJ.6.4.78","DOIUrl":"https://doi.org/10.29252/JORJANIBIOMEDJ.6.4.78","url":null,"abstract":"Medicinal herbs have always been closely related to humans and plants throughout the development of all civilizations. Although most plant species are known to date, there is still a long way to discover new and valuable herbal resources (1, 2). In this way, plants can be considered as a useful source of chemicals, only a part of which has been identified. These potentially useful chemicals can be used not only as a medicine but as an unrivaled model as the starting point for making pharmaceutical analogues, as well as Article Type: Original Article","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78867237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Expression of Bax and Bcl2 Apoptosis Biomarkers in the Heart of Old Female Rats After Interval Training and Curcumin Consumption","authors":"Bahareh Yazdanparast Chaharmahali, M. Azarbayjani, M. Peeri, Parvin Farzanegi Arkhazloo","doi":"10.29252/JORJANIBIOMEDJ.6.4.40","DOIUrl":"https://doi.org/10.29252/JORJANIBIOMEDJ.6.4.40","url":null,"abstract":"Elderly is described as a decrease in general physiological function (1). Gradual changes in the functions of a living creature ultimately lead to his death. Elderly is characterized by a decrease in cardiac function, including impulse volume, cardiac outflow, blood flow, oxygen uptake, and increased readiness for inflammation, oxidative stress, and diseases. With no heart functioning, inflammatory cytokines increase, and increased oxidative Article Type: Original Article","PeriodicalId":14723,"journal":{"name":"Jorjani Biomedicine Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86591270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}