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Inclusion of steps to enhance mucus clearance may provide benefit for symptomatic COVID patients by reducing total viral load, time to recovery, risk of complications and transmission risk 纳入加强粘液清除的步骤可能会通过减少病毒总载量、恢复时间、并发症风险和传播风险，为有症状的COVID患者带来益处
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/jrdm.1000129
J. Given, C. Steele
{"title":"Inclusion of steps to enhance mucus clearance may provide benefit for symptomatic COVID patients by reducing total viral load, time to recovery, risk of complications and transmission risk","authors":"J. Given, C. Steele","doi":"10.15761/jrdm.1000129","DOIUrl":"https://doi.org/10.15761/jrdm.1000129","url":null,"abstract":"","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115919877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
COVID-19, HIV and pulmonary tuberculosis. A triple threat to consider COVID-19、艾滋病毒和肺结核。需要考虑的三重威胁
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/JRDM.1000120
Jorge Arturo Valdivieso‐Jiménez, Ana Victoria Gaxiola-Ortiz, A. Cortés-Télles
{"title":"COVID-19, HIV and pulmonary tuberculosis. A triple threat to consider","authors":"Jorge Arturo Valdivieso‐Jiménez, Ana Victoria Gaxiola-Ortiz, A. Cortés-Télles","doi":"10.15761/JRDM.1000120","DOIUrl":"https://doi.org/10.15761/JRDM.1000120","url":null,"abstract":"Received: August 04, 2020; Accepted: August 18, 2020; Published: August 24, 2020 The World Health Organization declared the outbreak of novel SARS-CoV-2 as a pandemic in mid-March, 2020 [1]. The majority of coronavirus cases have a benign course, however, some strains have showed higher morbidity and mortality [2]. SARS-CoV-2 currently has an overall mortality rate of 14.6%. Most deaths in COVID-19 are reported in older patients with co-morbidities (23.7%), with systemic hypertension being the most frequent and only 0.2% related with medical history of immunosuppression [3]. Approximately 38 million people live with human immunodeficiency virus infection (HIV) and based on the available information, the rate of co-infection with COVID-19 is 0.92% [4,5]. On the other hand, roughly 10 million people suffer from tuberculosis (TB) worldwide, [6] nonetheless, there are few cases of co-infection with COVID-19 [7].","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114385014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The prone position in acute respiratory distress syndrome 急性呼吸窘迫综合征的俯卧位
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.3109/9780203912034-24
Nilay Kocoglu, U. Koca
{"title":"The prone position in acute respiratory distress syndrome","authors":"Nilay Kocoglu, U. Koca","doi":"10.3109/9780203912034-24","DOIUrl":"https://doi.org/10.3109/9780203912034-24","url":null,"abstract":"","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122438513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive support ventilation 自适应支撑通风
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/JRDM.1000114
U. Koca, Burcu Demirdöven
{"title":"Adaptive support ventilation","authors":"U. Koca, Burcu Demirdöven","doi":"10.15761/JRDM.1000114","DOIUrl":"https://doi.org/10.15761/JRDM.1000114","url":null,"abstract":"Adaptive support ventilation (ASV) is a closed-loop ventilation mode. Breath-to-breath dual control is applied. The factors that determine the amount of ventilatory support provided by the ventilator, the patient’s measured pulmonary mechanical properties and the patient’s pale effort stop. Forced breaths are machine-triggered, pressure-targeted, and time-cycled. As the target frequency is approached with spontaneous breaths, mandatory breaths decrease. Tidal volume, which is adapted to breath-to-breath lung mechanics, automatically removes the patient from the pressure support (weaning) as the patient’s lung mechanics and breathing efforts improve. The ASV algorithm determines the optimal respiratory pattern (VT and frequency) optimal for the patient by applying the concept of minimal respiratory work defined by Otis in 1950. This concept predicts breathing with VT and frequency, which minimalizes the cumulative effects of elastic and resistive loads created by the respiratory system and added to the system. Proper alveolar ventilation is provided while reducing the respiratory work of the patient and the ventilator. Since ASV can provide full or partial respiratory support, it can be used from the beginning of mechanical ventilation to weaning. ASV is a rule-based mode that guides the patient using the optimal breathing pattern to achieve minimum minute ventilation.","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128773127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comfortable fetal life, where fetal education was mandatory 舒适的胎儿生活，其中胎教是强制性的
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/jrdm.1000106
K. Maeda, M. Tatsumura
{"title":"Comfortable fetal life, where fetal education was mandatory","authors":"K. Maeda, M. Tatsumura","doi":"10.15761/jrdm.1000106","DOIUrl":"https://doi.org/10.15761/jrdm.1000106","url":null,"abstract":"The foetus needed no pulmonary respiration and no food taking before birth under the functions of placenta, while pulmonary respiration and food taking after delivery, also intrauterine life was supported by constant maternal temperature. There are many stresses after birth, thus, a foetus should be educated on postnatal life, but how? As the foetus is able to listen outside sound, it may be possible to be educated by the maternal speech on postnatal life. However, fetal hearing function was very particular, namely, fetal response was tested with 1,000, 500 and 250 Hz standard generator sounds, where fetal response to 80 and 60dB sounds was fetal movement then heart rate increase. The foetus clearly responded to 80 dB, 1,000 Hz sound and 12 weeks later decreased 60 dB, significantly. However, 500 and 250 Hs sound decreased but insignificantly, namely, the foetus clearly listened 1,000Hz sound, but insignificantly to the sound of adult conversation. The results confirmed it is mandatory to speak in 1,000 Hz voice, in fetal education, namely, a voice changer to 1,000 Hz is mandatory.","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125346447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of 95nm carbon black nanoparticles on inflammatory conditions in the murine lung - controversy to size dependent efficacy 95nm炭黑纳米颗粒对小鼠肺部炎症的影响——对大小依赖性疗效的争论
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/jrdm.1000127
Ken-ichiro Inoue, Kiri Yamada, Wakako Suzuki, H. Takano, A. Shimada
{"title":"Effects of 95nm carbon black nanoparticles on inflammatory conditions in the murine lung - controversy to size dependent efficacy","authors":"Ken-ichiro Inoue, Kiri Yamada, Wakako Suzuki, H. Takano, A. Shimada","doi":"10.15761/jrdm.1000127","DOIUrl":"https://doi.org/10.15761/jrdm.1000127","url":null,"abstract":"","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114747179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary myofibroblastic tumor – A forgotten lesion 肺肌成纤维细胞瘤——一种被遗忘的病变
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/JRDM.1000118
R. Rastogi, Neha, Y. Gupta, S. Bhargava, Vijai Pratap
{"title":"Pulmonary myofibroblastic tumor – A forgotten lesion","authors":"R. Rastogi, Neha, Y. Gupta, S. Bhargava, Vijai Pratap","doi":"10.15761/JRDM.1000118","DOIUrl":"https://doi.org/10.15761/JRDM.1000118","url":null,"abstract":"Pulmonary myofibroblastic tumor is a rare benign lesion often termed as inflammatory pseudotumor. It is a slow-growing, true neoplasm comprising less than 1% of pulmonary tumors thus forming a differential diagnosis of pulmonary tumors and infections in childhood and young adults. Complete resection results in cure unlike in many malignant lesions. Hence, this article tries to bring out the classical radiological features of this rare pseudo-malignant lesion in a young female along with its differential features.","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124912673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weaning 断奶
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/jrdm.1000116
U. Koca, Burcu T Demirdoven
{"title":"Weaning","authors":"U. Koca, Burcu T Demirdoven","doi":"10.15761/jrdm.1000116","DOIUrl":"https://doi.org/10.15761/jrdm.1000116","url":null,"abstract":"","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"2374 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130429319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary spontaneous pneumothorax after exposure to very loud music 暴露于非常大声的音乐后发生原发性自发性气胸
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/jrdm.1000103
I. Krivokuca, Lammers Jwj.
{"title":"Primary spontaneous pneumothorax after exposure to very loud music","authors":"I. Krivokuca, Lammers Jwj.","doi":"10.15761/jrdm.1000103","DOIUrl":"https://doi.org/10.15761/jrdm.1000103","url":null,"abstract":"Pneumothorax is the presence of air between the visceral and the parietal pleura of the lung [1-5]. Jean Marc Gaspard Itard, a student of Laennec, described five tuberculosis patients with pneumothorax in 1803 and introduced the word pneumothorax [6]. Pneumothoraces are usually subdivided into traumatic pneumothoraces which are the result of a chest trauma and non-traumatic (spontaneous) pneumothoraces which develop without preceding chest trauma. “Iatrogenic pneumothoraces” are a subtype of traumatic pneumothoraces which occur during or after certain diagnostic or therapeutic procedures like inserting a central line in the subclavian artery. Non-traumatic (spontaneous) pneumothoraces are subdivided into primary spontaneous pneumothorax when pulmonary parenchyma is apparently normal and secondary spontaneous pneumothorax which may occur after rupture of intrapulmonary bullae or blebs. Here we describe the occurrence of a primary spontaneous pneumothorax in a young man after listening to very loud music.","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124899734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interconnection of Mycobacterium tuberculosis with host immune system 结核分枝杆菌与宿主免疫系统的相互作用
Journal of Respiratory Diseases and Medicine Pub Date : 1900-01-01 DOI: 10.15761/JRDM.1000112
Ajit Kumar, Shivangi, Preeti Agarwal, L. Meena
{"title":"Interconnection of Mycobacterium tuberculosis with host immune system","authors":"Ajit Kumar, Shivangi, Preeti Agarwal, L. Meena","doi":"10.15761/JRDM.1000112","DOIUrl":"https://doi.org/10.15761/JRDM.1000112","url":null,"abstract":"Precise estimation of development of active tuberculosis (TB) infection from a latent Mycobacterium tuberculosis H 37 Rv (MTB) infection within host body signifies an indefinable and serious objective. Most of the infected individuals with excellent immune system are also at risk due to diverse local environmental and systemic factors. Therefore, it becomes mandatory to have a balance between pro and anti-immune regulators to work efficiently in optimized manner. This study thus signifies some essential factors involved in maintaining this balance and rescue host cellular environment from MTB infection. Inside host, MTB develops effective survival strategies, such as hampering of lysosome-phagosome fusion, hampering of phagosome acidification by a secretary protein phosphatase PtpA that binds to H subunit of V-ATPase to block V-ATPase transportation towards phagosome membrane, recruitment of TACO protein on phagosomal membrane to escape their transportation to lysosome. Bacterial infected cell undergoing apoptosis release ATP, UTP, LPC, S1P and several chemokines that intervene signaling of “find me” signal. Eventually, a balance between all these immunological factors must be set for optimized functioning of immune system against MTB. In this review we have elaborated various balancing mechanisms among pro and anti-inflammatory immune components that raise this disease from latent to active form. Through a brief and complete evaluation of different types of immune components that take part in host defense, we aimed to highlight the review with recent documented literatures to have a better and precise understanding of this disease. In conclusion, this review abridges various defensive strategies that moderate the distinct capability to fight MTB infection.","PeriodicalId":146691,"journal":{"name":"Journal of Respiratory Diseases and Medicine","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123431489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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