Irbm最新文献

{"title":"Study of an Optimization Tool Avoided Bias for Brain-Computer Interfaces Using a Hybrid Deep Learning Model","authors":"Nabil I. Ajali-Hernández ,&nbsp;Carlos M. Travieso-González ,&nbsp;Nayara Bermudo-Mora ,&nbsp;Patricia Reino-Cacho ,&nbsp;Sheila Rodríguez-Saucedo","doi":"10.1016/j.irbm.2024.100836","DOIUrl":"https://doi.org/10.1016/j.irbm.2024.100836","url":null,"abstract":"<div><h3>Objective</h3><p>This study addresses the challenge of user-specific bias in Brain-Computer Interfaces (BCIs) by proposing a novel methodology. The primary objective is to employ a hybrid deep learning model, combining 2D Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) layers, to analyze EEG signals and classify imagined tasks. The overarching goal is to create a generalized model that is applicable to a broader population and mitigates user-specific biases.</p></div><div><h3>Materials and Methods</h3><p>EEG signals from imagined motor tasks in the public dataset Physionet form the basis of the study. This is due to the need to use other databases in addition to the BCI competition. A model of arrays emulating the electrode arrangement in the head is proposed to capture spatial information using CNN, and LSTM algorithms are used to capture temporal information, followed by signal classification.</p></div><div><h3>Results</h3><p>The hybrid model is implemented to achieve a high classification rate, reaching up to 90% for specific users and averaging 74.54%. Error detection thresholds are set to eliminate subjects with low task affinity, resulting in a significant improvement in classification accuracy of up to 21.34%.</p></div><div><h3>Conclusion</h3><p>The proposed methodology makes a significant contribution to the BCI field by providing a generalized system trained on diverse user data that effectively captures spatial and temporal EEG signal features. This study emphasizes the value of the hybrid model in advancing BCIs, highlighting its potential for improved reliability and accuracy in human-computer interaction. It also suggests the exploration of additional advanced layers, such as transformers, to further enhance the proposed methodology.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 3","pages":"Article 100836"},"PeriodicalIF":4.8,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1959031824000174/pdfft?md5=982cd018a44984ae08fa196f365f8d5a&pid=1-s2.0-S1959031824000174-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140644996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Technology-Driven Technology Roadmaps (TRM) for Wearable Biosensors in Healthcare","authors":"Yu-Hui Wang","doi":"10.1016/j.irbm.2024.100835","DOIUrl":"https://doi.org/10.1016/j.irbm.2024.100835","url":null,"abstract":"<div><h3>Objectives</h3><p>This paper is proposed to identify both promising technologies and potential products in the domain of biosensor using patent-based Technology-Driven Technology Roadmaps (TRM).</p></div><div><h3>Materials and methods</h3><p>The technology-driven TRM with timelines in this study is developed in three layers: technology, function and product. Patent applications are collected and identified to interpret technologies and functions for biosensors in healthcare, and product manuals or releases can be used as product introductions.</p></div><div><h3>Results</h3><p>Most biosensors in healthcare patents are concentrated in biochemical (T2) and electroencephalography (T5). Glycated hemoglobin (F1), measuring of glucose (F3), and biological process and molecular systems (F6) have a relatively larger patent count. Biochemical (T2) can combine with biological process and molecular systems (F6), and then brain's real-time electrical activity monitoring can be handled. Biochemical (T2) can also devote to glycated hemoglobin (F1), and glucose monitoring (F3), and thus create QCM sensor, CGM and GlucoWatch etc. applications.</p></div><div><h3>Conclusion</h3><p>Biochemical (T2) has a wide application among different functions for wearable biosensors in healthcare. This paper identifies and explores new developments biochemical (T2), and electroencephalography (T5) in wearable biosensors are expected to play a significant role over the coming decade in improving the current healthcare infrastructure, and enhancing the democratization of information and allocation of medical resources.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 3","pages":"Article 100835"},"PeriodicalIF":4.8,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140644997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel QCT-Based Deep Transfer Learning Approach for Predicting Stiffness Tensor of Trabecular Bone Cubes","authors":"Pengwei Xiao ,&nbsp;Tinghe Zhang ,&nbsp;Yufei Huang ,&nbsp;Xiaodu Wang","doi":"10.1016/j.irbm.2024.100831","DOIUrl":"10.1016/j.irbm.2024.100831","url":null,"abstract":"<div><h3>Objectives</h3><p>This study was performed to prove the concept that transfer learning techniques, assisted with a generative model, could be used to alleviate the ‘big data’ requirement for training high-fidelity deep learning (DL) models in prediction of stiffness tensor of trabecular bone cubes.</p></div><div><h3>Material and methods</h3><p>Transfer learning approaches of domain adaptation were used, in which a source domain included 1,641 digital trabecular bone cubes synthesized from a generative model, and a target domain included 868 real trabecular bone cubes from human cadaver femurs. Simulated quantitative computed tomography (QCT) images of both the synthesized and real bone cubes were used as input, whereas the stiffness tensor of these cubes determined using finite element simulations were used as output. Three transfer learning algorithms, including instance-based (TrAdaBoostR2 and WANN) and parameter-based (RNN) methods, were used. Two case studies, one with varying sizes of training dataset and the other with a gender-biased training dataset, were performed to evaluate these deep transfer learning models in comparison with a base deep learning (DL) model trained using the dataset from the target domain.</p></div><div><h3>Results</h3><p>The results indicated that these deep transfer learning models were robust both to sample size and to the gender-biased training dataset, whereas the base DL model was very sensitive to such changes. Among the three transfer learning algorithms, the prediction accuracy of the RNN-based deep transfer learning model was the best (0.92-0.96%) and comparable to that of the base DL model trained using the dataset from the target domain.</p></div><div><h3>Conclusion</h3><p>This study proved the proposed concept and confirmed that high fidelity QCT-based deep learning models could be obtained for prediction of stiffness tensor of trabecular bone cubes.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 2","pages":"Article 100831"},"PeriodicalIF":4.8,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140166332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Order Temporal Convolutional Network for Improving Classification Performance of SSVEP-EEG","authors":"Jianli Yang,&nbsp;Songlei Zhao,&nbsp;Wei Zhang,&nbsp;Xiuling Liu","doi":"10.1016/j.irbm.2024.100830","DOIUrl":"10.1016/j.irbm.2024.100830","url":null,"abstract":"<div><h3>Background and objective</h3><p>Steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) aim to detect target frequencies corresponding to specific commands in electroencephalographic (EEG) signals by classification algorithms to achieve the desired control. However, SSVEP signals suffer from low signal-to-noise ratio and large differences in brain activity. Moreover, the existing CNN models have small receptive fields, which make it difficult to receive large range of feature information and limit the effectiveness of classification algorithms.</p></div><div><h3>Methods</h3><p>To this end, we proposed a high-order temporal convolutional neural network (HOT-CNN) model for enhancing the performance of SSVEP target recognition. Specifically, the SSVEP-EEG signals was divided into equal-length time segments and a time-slice attention module was designed to capture the correlation between time slices. The module improves the local characterization of signals and reduces biological noise interference by automatically assigning high weights to locally relevant temporal sampling cues and lower weights to other temporal cues. Moreover, for global features, a temporal convolutional network module was designed to increases the receptive field of the network and to extract more comprehensive time domain features by using dilated causal convolution. Finally, the fusion and analysis of local and global features are achieved by designing a feature fusion and classification module to accomplish accurate classification of SSVEP signals.</p></div><div><h3>Results</h3><p>Our method was evaluated on large publicly available datasets containing 35 subjects and 40 categories. Experimental results indicated that HOT-CNN achieved encouraging performance compared with other advanced methods: the highest information transfer rate of 241.01bits/min was obtained using 0.5s stimuli, and the highest average accuracy of 96.39% was obtained using 1.0s stimuli.</p></div><div><h3>Conclusions</h3><p>The method effectively reinforced the global and local time-domain information and improved the classification performance of SSVEP, which has wide application prospects.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 2","pages":"Article 100830"},"PeriodicalIF":4.8,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140106860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blockchain-Based Trusted Tracking Smart Sensing Network to Prevent the Spread of Infectious Diseases","authors":"Riaz Ullah Khan ,&nbsp;Rajesh Kumar ,&nbsp;Amin Ul Haq ,&nbsp;Inayat Khan ,&nbsp;Mohammad Shabaz ,&nbsp;Faheem Khan","doi":"10.1016/j.irbm.2024.100829","DOIUrl":"10.1016/j.irbm.2024.100829","url":null,"abstract":"<div><h3>Background</h3><p>Infectious diseases like COVID-19 pose major global health threats. Robust surveillance systems are needed to swiftly detect and contain outbreaks. This study investigates the integration of Blockchain technology and machine learning to establish a secure and ethically sound approach to tracking infectious diseases.</p></div><div><h3>Methods</h3><p>We established a Blockchain-based framework for the collection and analysis of epidemiological data while upholding privacy standards. We employed encryption and privacy-enhancing technologies to gather information on case numbers, locations, and disease progression. Artificial neural networks were employed to scrutinize the data and pinpoint transmission patterns. A prototype was specifically designed to work with COVID-19 data from specific countries.</p></div><div><h3>Results</h3><p>The Blockchain system enabled reliable and tamper-proof data gathering with enhanced transparency. The evaluation showed it allowed cost-effective tracking of infectious diseases while upholding confidentiality safeguards. The neural networks effectively modeled disease spread based on the Blockchain data.</p></div><div><h3>Conclusions</h3><p>This research demonstrates the viability of Blockchain and machine learning for infectious disease surveillance. The system strikes a balance between public health concerns and personal privacy considerations. It also addresses the challenges of misinformation and accountability gaps during disease outbreaks. Ongoing development can lay the foundation for an ethical framework for digital disease tracking, ensuring both pandemic preparedness and response capabilities are upheld.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 2","pages":"Article 100829"},"PeriodicalIF":4.8,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139813901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Applications in Ophthalmology: A Review","authors":"Sylvain Poinard ,&nbsp;Alice Ganeau ,&nbsp;Maxime Lafond ,&nbsp;Oliver Dorado ,&nbsp;Stefan Catheline ,&nbsp;Cyril Lafon ,&nbsp;Florent Aptel ,&nbsp;Gilles Thuret ,&nbsp;Philippe Gain","doi":"10.1016/j.irbm.2024.100828","DOIUrl":"10.1016/j.irbm.2024.100828","url":null,"abstract":"<div><p>Ultrasound is a powerful tool in ophthalmology with a wide range of physical effects that can interact with biological tissue. This ranges from low-intensity linear transducers for diagnosis to high-intensity pulsed or continuous focused ultrasound for therapy. Designing devices for ophthalmological applications requires creating fine focal spots, minimizing heating, and accounting for eye movements. Ultrasound is essential for ophthalmologists to provide accurate diagnosis and quantitative information on tissue composition and blood flow. Ultrasound has revolutionized cataract surgery, making it less invasive and in an outpatient basis, while enhancing the safety and predictability of glaucoma treatment using high-intensity focused ultrasound. The article aims to review the complex and multifaceted bioeffects of ultrasound used in ophthalmology, and its current and future applications of ultrasound in ophthalmology, notably regarding cavitation-mediated drug delivery.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 2","pages":"Article 100828"},"PeriodicalIF":4.8,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139828638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledging our reviewers","authors":"","doi":"10.1016/S1959-0318(24)00006-X","DOIUrl":"https://doi.org/10.1016/S1959-0318(24)00006-X","url":null,"abstract":"","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 1","pages":"Article 100825"},"PeriodicalIF":4.8,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S195903182400006X/pdfft?md5=7b99a7407da8ee505b1e0120628c3e03&pid=1-s2.0-S195903182400006X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139719191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stylohyoid and Posterior Digastric Recruitment Pattern Evaluation in Swallowing and Non-swallowing Tasks","authors":"Adrien Mialland ,&nbsp;Ihab Atallah ,&nbsp;Agnès Bonvilain","doi":"10.1016/j.irbm.2024.100823","DOIUrl":"10.1016/j.irbm.2024.100823","url":null,"abstract":"<div><h3>Objectives</h3><p>Electromyography is one of the few measurement methods that can be implanted, and it has been used in swallowing detection to measure superficial muscles, but has failed to provide satisfactory performances for a real-time detection. Yet, we seek to allow for the feasibility of an implantable active artificial larynx that would protect the airway during swallowing. Therefore, it requires a real-time detection of swallowing through measurements that must provide dedicated and early activity on swallowing, to close the airways soon as possible. In that regard, promising results were published about the stylohyoid and posterior digastric muscles, but no study provided simultaneous and independent measurements. So, this paper aims to evaluate both muscles with intra muscular EMG, in a large set of tasks, to evaluate their recruitment pattern for the feasibility of an implantable active artificial larynx.</p></div><div><h3>Materials and methods</h3><p>we used intramuscular EMG to measure the stylohyoid and the posterior digastric muscles independently. We also used surface electrodes to measure the submental muscles and provide a basis for comparison. Besides, the swallowing sound measurement method was used to locate the moment the bolus starts to enter the upper esophageal sphincter (UES). That moment defines a temporal limit after which the airway are in danger of aspiration and the temporal evolution of the muscles' is evaluated in comparison to that limit. The onsets and offsets of each muscles were located with a generalized likelihood ratio method, and the UES bolus passage was localized manually after the transformation of the signals with a Teager-Kaiser energy operator. 17 participants were measured, and were asked to perform 4 swallowing tasks and 13 non-swallowing tasks.</p></div><div><h3>Results</h3><p>we found a strong implication of the stylohyoid for swallowing and mastication. The posterior digastric showed a clear tendency towards swallow-related tasks, and especially swallowing, mastication, open mouth, jaw, and clench teeth. Both muscles provided significant activity before the temporal limit, with a characteristic pattern.</p></div><div><h3>Conclusion</h3><p>the stylohyoid and the posterior digastric muscles shows a net increase in potential for a detection, compared to the submental muscles, for the feasibility of an implantable active artificial larynx.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 2","pages":"Article 100823"},"PeriodicalIF":4.8,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139827724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved Estimation of Elbow Flexion Angle from IMU Measurements Using Anatomical Constraints","authors":"Anna Bicchi,&nbsp;Alessandro Colombo","doi":"10.1016/j.irbm.2024.100820","DOIUrl":"10.1016/j.irbm.2024.100820","url":null,"abstract":"<div><h3>Objectives</h3><p>Inertial Measurement Units (IMUs) are a valid alternative to optical tracking systems for human motion capture, but they are subject to several disturbances that limit their accuracy. We aim to improve the accuracy of elbow joint angle estimation from IMU measurements by introducing a novel postprocessing algorithm that uses anatomical constraints and does not require any prior calibration or knowledge of anthropometric parameters.</p></div><div><h3>Materials and Methods</h3><p>We propose a new error model that addresses sensor misalignment and fusion errors. We use an error state extended Kalman filter (ESEKF) with state constraints to integrate the anatomical constraints. We validate the proposed algorithm by testing it in different scenarios and comparing it with a state-of-the-art optical tracking system.</p></div><div><h3>Results</h3><p>The research results highlight the superior performance of the proposed method compared with existing techniques. The study demonstrates a significant reduction in errors, particularly in complex arm movements and under strong external disturbances. The results obtained in the three different tested scenarios underscore the robustness and effectiveness of the developed algorithm, reaching half the error committed by the existing calibration-free correction algorithms proposed in the literature.</p></div><div><h3>Conclusions</h3><p>The developed technique provides highly accurate estimates of joint angles in several challenging real-world scenarios.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 1","pages":"Article 100820"},"PeriodicalIF":4.8,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1959031824000010/pdfft?md5=4603b04f7a7d6f3268a7480f4b5a8476&pid=1-s2.0-S1959031824000010-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139482135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Two Bootstrapped Regions in Images: The D-Test","authors":"Florentin Kucharczak ,&nbsp;Inés Couso ,&nbsp;Olivier Strauss ,&nbsp;Denis Mariano-Goulart","doi":"10.1016/j.irbm.2024.100821","DOIUrl":"10.1016/j.irbm.2024.100821","url":null,"abstract":"<div><h3>Objectives</h3><p>Many molecular imaging diagnoses involve comparing two regions of interest (ROIs) in the image or different images. Since the images are obtained by measuring a random phenomenon, such comparisons should be based on a statistical test to ensure reliability. Recent studies have shown that use of the bootstrap approach provides access to the statistical variability of reconstructed values in molecular images. However, although there is general agreement that this increase in information should make diagnosis based on molecular images more reliable, no approach has been proposed in the relevant literature to use bootstrap replicates to enhance the reliability of comparisons of two ROIs. In this paper, we propose to fill this gap by introducing the first statistical test that allows us to compare two sets of pixels/voxels for which bootstrap replicates are available.</p></div><div><h3>Material and methods</h3><p>After presenting the theoretical basis of this non-parametric statistical test, this article describes how to calculate it in practice. Finally, it proposes two experiments based on quantitative comparisons and expert judgment to assess its relevance.</p></div><div><h3>Results</h3><p>The results obtained are consistent with expert diagnosis on synthetic data. This validates the relevance of the D-test.</p></div><div><h3>Conclusion</h3><p>This paper presents the first statistical test to compare two ROIs in reconstructed images for which the statistical variability information is accessible.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":"45 1","pages":"Article 100821"},"PeriodicalIF":4.8,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1959031824000022/pdfft?md5=8064e78cbcbc3824ad2b83a752908c7b&pid=1-s2.0-S1959031824000022-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139499353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}