Investigative and Clinical Urology最新文献_第9页

Comparing the accuracy of the urinary tract infection symptom assessment and the acute cystitis symptom score questionnaires in diagnosis of acute uncomplicated cystitis in women. 比较尿路感染症状评估与急性膀胱炎症状评分问卷对女性急性无并发症膀胱炎诊断的准确性。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20240380

Yi-Ju Chou, Shang-Jen Chang, Stephen Shei-Dei Yang

{"title":"Comparing the accuracy of the urinary tract infection symptom assessment and the acute cystitis symptom score questionnaires in diagnosis of acute uncomplicated cystitis in women.","authors":"Yi-Ju Chou, Shang-Jen Chang, Stephen Shei-Dei Yang","doi":"10.4111/icu.20240380","DOIUrl":"10.4111/icu.20240380","url":null,"abstract":"Purpose: The purpose of this study is to compare the accuracy of two commonly used questionnaires in diagnosing acute cystitis, i.e., the urinary tract infection symptom assessment (UTISA) and the acute cystitis symptom score (ACSS) questionnaires.Materials and methods: From April 2021 to December 2022, we enrolled female patients with suspected symptoms of acute cystitis as the patient group. As a control group, we included asymptomatic females who came to the hospital for health check-ups. We calculated the accuracy of the two questionnaires in diagnosing acute cystitis and compared the difference in the area under the curve (AUC) of the two through the DeLong test.Results: A total of 89 and 43 participants were recruited for the patient and control groups, respectively. Both questionnaires include six symptoms: frequency, urgency, dysuria, incomplete bladder emptying, lower abdominal pain, and hematuria to diagnose acute cystitis. However, UTISA includes lower back pain as the 7th symptom. The sensitivity, specificity, and AUC of UTISA and ACSS were 85.4% versus 75.3% (p=0.091), 93.0% versus 93.0% (p>0.999), and 0.96 (95% CI 0.92-0.99) versus 0.90 (95% CI 0.83-0.94) (p<0.001), respectively.Conclusions: UTISA questionnaire demonstrates higher diagnostic accuracy compared to ACSS questionnaire. ACSS has lower sensitivity probably due to its limited assessment of low back pain and the objective definition of the severity of frequency that prevents patients from responding based on subjective severity.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"352-358"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive value of tumor invasion patterns on intravesical bacillus Calmette-Guérin response for stage T1 high-grade non-muscle-invasive bladder cancer. 肿瘤侵袭模式对膀胱内calmette - gusamrin反应对T1期高级别非肌侵性膀胱癌的预测价值。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250124

Ismail Ulus, Şule Özsoy, Selçuk Cin, Mehmet Yilmaz, Gokhan Cil, İbrahim Oğulcan Canitez, Atilla Semercioz

{"title":"Predictive value of tumor invasion patterns on intravesical bacillus Calmette-Guérin response for stage T1 high-grade non-muscle-invasive bladder cancer.","authors":"Ismail Ulus, Şule Özsoy, Selçuk Cin, Mehmet Yilmaz, Gokhan Cil, İbrahim Oğulcan Canitez, Atilla Semercioz","doi":"10.4111/icu.20250124","DOIUrl":"10.4111/icu.20250124","url":null,"abstract":"Purpose: Parameters predicting intravesical bacillus Calmette-Guerin (BCG) treatment response in non-muscle-invasive bladder cancer (NMIBC) are limited. This study investigated the effectiveness of tumor invasion patterns in predicting intravesical BCG treatment response, which are known to have prognostic value for NMIBC.Materials and methods: Data of 167 primary, stage T1 high-grade NMIBC patients evaluated retrospectively. All transurethral resection samples were re-evaluated for confirmation of pathological variables and determination of invasion patterns. Binary logistic regression analysis applied to obtain determinants of BCG response. Kaplan-Meier curves and log-rank test used to assess relationship between variables and time to recurrence and time to progression.Results: Tumor invasion pattern was nodular in 83 (49.7%), trabecular in 20 (12.0%) and infiltrative in 64 patients (38.3%). Multivariate analysis revealed multifocality (p=0.001), trabecular invasion (p=0.001) and infiltrative invasion (p=0.001) were independent predictors of poor BCG response. Log-rank test determined infiltrative invasion has higher impact on time to recurrence (p<0.001) and nodular invasion has significantly lower risk for time to progression (p=0.013), during the median follow-up period of 15 months.Conclusions: Invasion patterns are significantly correlated with BCG response. Assessment of this easily applicable parameter can differ patients who may benefit from BCG treatment and can be used as a prognostic indicator.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"295-301"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of regular cystoscopy on prognosis in non-muscle-invasive bladder cancer: A nationwide study. 定期膀胱镜检查对非肌肉浸润性膀胱癌预后的影响：一项全国性研究。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20240362

Jeong-Soo Kim, Jooyoung Lee, Chung Un Lee, Tuan Thanh Nguyen, Se Young Choi

{"title":"Impact of regular cystoscopy on prognosis in non-muscle-invasive bladder cancer: A nationwide study.","authors":"Jeong-Soo Kim, Jooyoung Lee, Chung Un Lee, Tuan Thanh Nguyen, Se Young Choi","doi":"10.4111/icu.20240362","DOIUrl":"10.4111/icu.20240362","url":null,"abstract":"Purpose: Transurethral resection of bladder tumors (TUR-BT) requires follow-up evaluation by cystoscopy. We sought to evaluate the prognosis of non-muscle-invasive bladder cancer (NMIBC) patients within 6 months of surgery to identify the optimal timing for the first cystoscopy after TUR-BT.Materials and methods: In this retrospective analysis, patients newly diagnosed with NMIBC were divided into two groups according to whether they underwent cystoscopy within 6 months after TUR-BT. We considered four outcomes: recurrence, progression, cancer-specific mortality, and all-cause mortality. Inverse probability treatment weighting (IPTW)-adjusted Kaplan-Meier analysis was performed to identify the difference in survival for each outcome stratified by cystoscopy status within 6 months after the first TUR-BT. We employed Cox regression models with IPTW to estimate the hazard ratios (HRs) of each outcome according to cystoscopy status.Results: Among 40,678 patients, 11,940 (29.4%) did not undergo cystoscopy within 6 months. The risk of recurrence was higher for patients who underwent cystoscopy than those who did not (HR 1.32, 95% confidence interval [CI] 1.26-1.38, p<0.001). By contrast, the cystoscopy group had a lower risk of progression compared to the non-cystoscopy group (HR 0.70, 95% CI 0.65-0.76, p<0.001), with lower cancer-specific mortality (HR 0.62, 95% CI 0.56-0.68, p<0.001) and all-cause mortality (HR 0.58, 95% CI 0.56-0.60, p<0.001).Conclusions: Cystoscopy within 6 months was associated with a higher risk of recurrence but a lower risk of progression and death. Therefore, regular cystoscopy after the first TUR-BT for NMIBC is essential to ensure favorable survival outcomes.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"302-310"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience. 使用PrecisionPoint™经会阴准入系统，局部麻醉下经会阴前列腺活检疼痛和耐受性的患者报告结果测量：一项真实患者体验的前瞻性研究。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250077

Ahmed Tarek Albnhawy, Ayman Mostafa, Eslam Hussain, George Hanna, Shweta Das, Asmita Hossain, Moumn Abdalla, Jordan Durrant, Panagiotis Papikinos

{"title":"Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience.","authors":"Ahmed Tarek Albnhawy, Ayman Mostafa, Eslam Hussain, George Hanna, Shweta Das, Asmita Hossain, Moumn Abdalla, Jordan Durrant, Panagiotis Papikinos","doi":"10.4111/icu.20250077","DOIUrl":"10.4111/icu.20250077","url":null,"abstract":"Purpose: Prostate biopsy remains the key step in prostate cancer detection. In recent years, the PrecisionPoint™ Transperineal Access System (PPTAS) has been described as an effective and safe method for performing transperineal biopsy under local anaesthesia (LA). The authors report on the real-world experience of the procedure.Materials and methods: Following introduction and familiarity with the PPTAS biopsy method, patients undergoing prostate biopsy for suspected prostate cancer were provided with validated questionnaires to rate their pain and discomfort following the procedure. The experience of LA administration and the experience of the biopsies were rated separately and prospectively. In addition, the number of cores, maximum core length (MCL), detection rate, and complication rate were retrospectively collected.Results: One hundred three patients were recruited to the study, and a final number of 86 completed patient-reported outcome measures (PROMs) forms were analysed. The procedure was described as tolerable by 97.7%, causing discomfort in 70.9%-88.4%. The grade of pain or discomfort in 73.3%-87.2% was <4 on the pain scale, with only 5.8%-9.3% describing a pain grade >5 on the pain scale. The number of cores, MCL, detection rate, and complication rate were within accepted rates.Conclusions: In a real-world setting, the procedure showed satisfactory PROMs with good patient tolerability and a low grade of pain. Also, it showed a good biopsy quality, detection rate, and complications rate, meaning PPTAS should be considered by centers seeking to streamline the prostate cancer detection pathway for patients.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"311-319"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Connecting the dots: How functional bladder capacity may reflect cardiovascular risk. 连接点：膀胱功能容量如何反映心血管风险。

IF 2.5 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20240405

Momina Ahmed, Hafiz Muhammad Haris, Hafsa Zareen

引用次数: 0

A novel T-shaped incision of the tunica vaginalis for managing adhesions during vasoepididymostomy. 一种新型的阴道膜t形切口用于处理附睾血管吻合术中的粘连。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250011

Zhuojie Liu, Jiarong Feng, Karl H Pang, Hao Zhang, Yan Zhang

{"title":"A novel T-shaped incision of the tunica vaginalis for managing adhesions during vasoepididymostomy.","authors":"Zhuojie Liu, Jiarong Feng, Karl H Pang, Hao Zhang, Yan Zhang","doi":"10.4111/icu.20250011","DOIUrl":"10.4111/icu.20250011","url":null,"abstract":"Purpose: To propose a novel surgical approach for managing inflammatory adhesions of the tunica vaginalis (TV) during vasoepididymostomy (VE), and to report surgical outcomes.Materials and methods: A T-shaped incision of the TV was used to expose the epididymis and vas deferens in cases with adhesions between the TV and the testis. We retrospectively analyzed data from five patients who underwent microsurgical VE for obstructive azoospermia (OA) secondary to epididymal obstruction. Operative time, postoperative patency rate and semen analysis, and natural pregnancy rates were recorded. For comparison, 50 patients who underwent conventional longitudinal TV incision were included to assess operative time, while 46 and 36 of these patients were used to compare patency and pregnancy rates, respectively, with the T-shaped incision group.Results: The T-shaped incision involves a longitudinal incision of the TV at the epididymal-testicular junction followed by an incision (T) in the direction towards the epididymis and vas deferens area. Among the five patients who underwent this approach, four (80.0%) had sperm detected in semen two months postoperatively, and their partners achieved natural pregnancy (4/5, 80.0%) within one year after VE. No postoperative wound infections occurred. No statistically significant differences were observed in mean operative time, patency rates, or pregnancy rates between the T-shaped and longitudinal incision groups.Conclusions: The T-shaped TV incision is a feasible approach for VE in OA patients with inflammatory TV-testis adhesions, providing adequate epididymal access without compromising operative time or surgical outcomes.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"329-335"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the editor: Computerized metric assessment of glandular tissue volume within the peripheral zone of the prostate using combined magnetic resonance imaging and histopathology: Possible pathophysiological implications on prostate cancer development. 致编辑的信：结合磁共振成像和组织病理学对前列腺外周区腺体组织体积的计算机度量评估：前列腺癌发展的可能病理生理意义。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250045

Kuo-Jen Lin, Po-Ting Lin, Yu-Hsiang Lin

引用次数: 0

Totally intracorporeal ileal neobladder following robot-assisted radical cystectomy in male patients using the Juntendo technique: Initial experience. 使用Juntendo技术的男性患者在机器人辅助根治性膀胱切除术后的完全体内回肠新膀胱：初步经验。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250112

Fumitaka Shimizu, Satoru Muto, Kosuke Kitamura, Tomoki Kimura, Toshiyuki China, Shigeo Horie

{"title":"Totally intracorporeal ileal neobladder following robot-assisted radical cystectomy in male patients using the Juntendo technique: Initial experience.","authors":"Fumitaka Shimizu, Satoru Muto, Kosuke Kitamura, Tomoki Kimura, Toshiyuki China, Shigeo Horie","doi":"10.4111/icu.20250112","DOIUrl":"10.4111/icu.20250112","url":null,"abstract":"Purpose: We developed a totally intracorporeal neobladder (ICNB) reconstruction technique, termed the Juntendo technique, which features a more spherical configuration by advancing from a hybrid neobladder reconstruction approach. In this report, we describe this ICNB procedure and its outcomes from our initial clinical experience.Materials and methods: Between March 2022 and December 2024, 20 male patients underwent neobladder reconstruction (hybrid reconstruction in the first 10 and totally intracorporeal reconstruction in the other 10) following robot-assisted radical cystectomy. The reconstruction technique involved detubularization of a 40 cm ileal segment, formation of a spiral posterior wall plate for vertical traction resistance, and circumferential urethroileal anastomosis without a separate enterotomy. The ureters were anastomosed to a 10 cm afferent limb using the Wallace technique. Subsequently, clinical and perioperative outcomes were collected and compared between the hybrid and ICNB groups.Results: The estimated blood loss or operative time did not significantly differ between the two groups. In both cohorts, no major perioperative complications occurred, and postoperative renal function remained stable. Both groups also achieved high continence rates. At 3-6 months postoperatively, the ICNB group obtained mean values of 174.9 mL for the neobladder volume, 24.2 mL/s for the maximum flow rate, and 10 mL for the post-void residual volume.Conclusions: ICNB reconstruction using the Juntendo technique is safe and feasible as the hybrid approach while also yielding favorable early functional outcomes. Studies involving larger patient cohorts and longer follow-up periods is warranted for further validation of this technique.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"320-328"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining adherence to American Urological Association (AUA) guidelines in men's health: Insights from the New York section AUA survey. 检查美国泌尿协会（AUA）男性健康指南的依从性：来自纽约部分AUA调查的见解。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250067

Hunter Hernandez, John Fastenau, Ari Bernstein, Hossein Sadeghi-Nejad

{"title":"Examining adherence to American Urological Association (AUA) guidelines in men's health: Insights from the New York section AUA survey.","authors":"Hunter Hernandez, John Fastenau, Ari Bernstein, Hossein Sadeghi-Nejad","doi":"10.4111/icu.20250067","DOIUrl":"10.4111/icu.20250067","url":null,"abstract":"Purpose: With the introduction of the AUA Quality Registry (AQUA), physician practice styles and adherence to clinical guidelines are under closer scrutiny. While adherence is critical for optimal healthcare, it has not been studied in men's health. This survey-based study assessed adherence to American Urological Association (AUA) clinical guidelines on erectile dysfunction (ED), Peyronie's disease, priapism, infertility, and ejaculatory disorders among members of the New York section of the AUA.Materials and methods: An anonymous questionnaire was emailed to members, covering five non-oncologic men's health guideline categories. Each category included two to four specific guidelines, with responses recorded on a Likert scale. Respondents could provide rationale for their answers or omit questions if they did not treat a specific condition.Results: Among 82 urologists, most treated ED and ejaculatory dysfunction but less commonly treated Peyronie's, priapism, and infertility. Some guidelines were frequently not followed. For instance, 57% never prescribed tramadol or α1-adrenoreceptor antagonists for premature ejaculation after first-line therapy failure. Half never performed in-office intracavernosal injection tests for Peyronie's. For priapism, 52% never used ultrasound in initial evaluations, and 45% rarely referred men with ED to mental health professionals.Conclusions: This pilot study highlights generally high adherence to AUA guidelines but identifies gaps in areas driven by expert opinion. Findings suggest a need for targeted educational initiatives, particularly in Peyronie's diagnosis and mental health integration for ED, to enhance patient care and outcomes. Such initiatives are crucial in refining the approach to men's health, ultimately enhancing patient care and outcomes.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"336-343"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting angiomyolipomas: The significance of a rich blood supply on imaging for risk-adapted decision making. 重访血管平滑肌脂肪瘤：富血供对风险适应决策成像的意义。

IF 2.9 3区医学

Investigative and Clinical Urology Pub Date : 2025-07-01 DOI: 10.4111/icu.20250059

David Alonso López Curtis, Alberto Artiles Medina, José Daniel Subiela, Ana Fernández-Mardomingo Díaz, Fernando González Tello, Alfonso Muriel García, Irene de la Parra Sánchez, César Mínguez Ojeda, Miguel Ángel Jiménez Cidre, Victoria Gómez Dos Santos, Francisco Javier Burgos Revilla

{"title":"Revisiting angiomyolipomas: The significance of a rich blood supply on imaging for risk-adapted decision making.","authors":"David Alonso López Curtis, Alberto Artiles Medina, José Daniel Subiela, Ana Fernández-Mardomingo Díaz, Fernando González Tello, Alfonso Muriel García, Irene de la Parra Sánchez, César Mínguez Ojeda, Miguel Ángel Jiménez Cidre, Victoria Gómez Dos Santos, Francisco Javier Burgos Revilla","doi":"10.4111/icu.20250059","DOIUrl":"10.4111/icu.20250059","url":null,"abstract":"Purpose: Active surveillance is the preferred management for most renal angiomyolipomas (AMLs) but no risk-adapted follow-up strategy has been established. We aimed to assess the dynamics associated with hemorrhagic complications (HC) and tumor growth (TG) at long-term follow-up of AMLs.Materials and methods: A single-center retrospective study was conducted, enrolling patients with an AML diagnosed by computed tomography or magnetic resonance imaging. Kaplan-Meier analyses were performed to estimate HC risk and multivariate logistic regression analyses were carried out to evaluate predictors of TG and HC.Results: A total of 150 patients were included. The median follow-up was 64.5 months (interquartile range [IQR] 25-102). Median tumor size at diagnosis was 14 mm (IQR 8-26). During follow-up, 12 patients (8.0%) required selective angioembolization, including 6 in whom the procedure was urgent due to spontaneous bleeding. At 5 years of follow-up, we found a 4.5% risk of HC and 3.6% of patients had a clinically significant growth rate of ≥3 mm/year. The existence of a rich blood supply (odds ratio [OR] 11.10, 95% confidence interval [CI] 1.68-23.54), and the size of AMLs at diagnosis (OR 1.02, 95% CI 1.01-1.04) were predictors for HC.Conclusions: Renal AMLs have a minimal size progression and a very low risk of HC, allowing use of active surveillance as a first-line approach. Imaging features, such as the existence of a rich blood supply, could be useful in identifying patients at higher risk of bleeding for the purpose of risk-adapted decision making.","PeriodicalId":14522,"journal":{"name":"Investigative and Clinical Urology","volume":"66 4","pages":"285-294"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0