{"title":"Methods of Preparation of Nanoparticle Formulations for the Treatment of COPD","authors":"Suprio R. Paul, S. Nayak, A. Anis, K. Pal","doi":"10.4018/978-1-7998-8591-7.ch017","DOIUrl":"https://doi.org/10.4018/978-1-7998-8591-7.ch017","url":null,"abstract":"The incidence of chronic obstructive pulmonary disease (COPD) has increased many folds in the last couple of decades. This can be explained by the increased pollution levels and drastic changes in the lifestyle of the people. Taking a note of this, in this review, a conscious attempt was made to understand the physiological changes in the respiratory tract in a COPD patient. Nanoparticulate formulations play an extensive role in the current-day treatment regime of COPD patients. Hence, different methods for developing nanoparticulate formulations for the treatment of COPD are discussed in details.","PeriodicalId":145165,"journal":{"name":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","volume":"306 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116226593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ionic Liquid-Mediated Synthesis of Metal Nanoparticles","authors":"V. Srivastava","doi":"10.4018/978-1-7998-1241-8.ch017","DOIUrl":"https://doi.org/10.4018/978-1-7998-1241-8.ch017","url":null,"abstract":"In this chapter, the authors discussed the recent as well as significant development in the synthesis of ionic liquid-mediated nanoparticles (considered a less toxic way to make nanoparticles). Apart from that, they also disused a small background of ionic liquid considering types, properties, and effect of ionic liquid's counterparts on nanoparticles synthesis. There are promising consequences proposing that the ionic liquid route can lead the design and fabrication of nanoparticles through the variety of size, nature, configuration, and functionality. All discussed examples in this chapter clearly depicted that ionic liquids add great value to the area of nanoparticle synthesis.","PeriodicalId":145165,"journal":{"name":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122970499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced Heat Transfer Mechanism of Nanofluids Minimum Lubrication Grinding","authors":"Changhe Li, H. Ali","doi":"10.4018/978-1-7998-1546-4.ch002","DOIUrl":"https://doi.org/10.4018/978-1-7998-1546-4.ch002","url":null,"abstract":"This chapter will discuss in detail the various aspects of nanofluids, form preparation of nanofluids, characterization and flow and energy transportation mechanisms of nanofluids. Preparation of nanofluids has been performed using various methods where one step and two step methods are widely known. These methods are discussed in detail for various nanoparticles with stabilizing agents for stable production of nanofluids. Further, the characterization techniques of various aspects of nanofluds including thermal conductivity and factors influencing the thermal conductivity of nanofluids are introduced in depth. The chapter also sheds light on the experimental analysis of flow and heat transfer of naofluids, natural convection analysis of naofluids, and boiling heat transfer of nanofluids.","PeriodicalId":145165,"journal":{"name":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","volume":"178 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116341729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mesoporous Silica Nanoparticles","authors":"Viney Lather, Neelam Poonia, D. Pandita","doi":"10.4018/978-1-5225-4781-5.CH008","DOIUrl":"https://doi.org/10.4018/978-1-5225-4781-5.CH008","url":null,"abstract":"Integration of nanotechnology and biomedicine has offered great opportunities for the development of nanoscaled therapeutic platforms. Amongst various nanocarriers, mesoporous silica nanoparticles (MSNs) is one of the most developed and promising inorganic materials-based drug delivery system for clinical translations due to their simple composition and nanoporous structure. MSNs possess unique structural features, for example, well-defined morphology, large surface areas, uniform size, controllable structure, flexible pore volume, tunable pore sizes, extraordinarily high loading efficiency, and excellent biocompatibility. Progress in structure control and functionalization may endow MSNs with functionalities that enable medical applications of these integrated nanoparticles such as molecularly targeted drug delivery, multicomponent synergistic therapy, in vivo imaging and therapeutic capability, on-demand/stimuli-responsive drug release, etc. In this chapter, the authors overview MSNs' characteristics and the scientific efforts developed till date involving drug delivery and biomedical applications.","PeriodicalId":145165,"journal":{"name":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131814870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anamika Jain, Laxmikant Gautam, Nikhar Vishwakarma, Rajeev Sharma, N. Mody, S. Dubey, S. Vyas
{"title":"Emergence of Polymer-Lipid Hybrid Systems in Healthcare Scenario","authors":"Anamika Jain, Laxmikant Gautam, Nikhar Vishwakarma, Rajeev Sharma, N. Mody, S. Dubey, S. Vyas","doi":"10.4018/978-1-5225-4781-5.CH017","DOIUrl":"https://doi.org/10.4018/978-1-5225-4781-5.CH017","url":null,"abstract":"Nanotechnology has drawn the attention of many researchers for the delivery of therapeutics used in various medical applications. Liposomes and polymeric nanoparticles represent promising nanocarriers that efficiently encapsulate drugs, which prevents their degradation along with the control and sustained drug release. Despite the many advantages of these formulations, some of the drawbacks associated with them limit their application to a certain extent. Therefore, there is need for a novel nanocarrier that possesses all of their individual advantages and excludes their drawbacks. Currently, researchers are focused on developing a novel platform that is a hybrid of a polymeric and liposomal-based carrier that combines the peculiarity of both and excludes their shortcomings. Lipid hybrid polymer nanoparticles (LPNs) contain the hydrophobic biodegradable polymeric core surrounded by a lipid layer for intensification of biocompatibility. This chapter includes an introduction of LPNs along with their advantages, composition, and method of preparation.","PeriodicalId":145165,"journal":{"name":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122256402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}