Mesoporous Silica Nanoparticles

Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials Pub Date : 1900-01-01 DOI:10.4018/978-1-5225-4781-5.CH008

Viney Lather, Neelam Poonia, D. Pandita

{"title":"Mesoporous Silica Nanoparticles","authors":"Viney Lather, Neelam Poonia, D. Pandita","doi":"10.4018/978-1-5225-4781-5.CH008","DOIUrl":null,"url":null,"abstract":"Integration of nanotechnology and biomedicine has offered great opportunities for the development of nanoscaled therapeutic platforms. Amongst various nanocarriers, mesoporous silica nanoparticles (MSNs) is one of the most developed and promising inorganic materials-based drug delivery system for clinical translations due to their simple composition and nanoporous structure. MSNs possess unique structural features, for example, well-defined morphology, large surface areas, uniform size, controllable structure, flexible pore volume, tunable pore sizes, extraordinarily high loading efficiency, and excellent biocompatibility. Progress in structure control and functionalization may endow MSNs with functionalities that enable medical applications of these integrated nanoparticles such as molecularly targeted drug delivery, multicomponent synergistic therapy, in vivo imaging and therapeutic capability, on-demand/stimuli-responsive drug release, etc. In this chapter, the authors overview MSNs' characteristics and the scientific efforts developed till date involving drug delivery and biomedical applications.","PeriodicalId":145165,"journal":{"name":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4018/978-1-5225-4781-5.CH008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 10

Abstract

Integration of nanotechnology and biomedicine has offered great opportunities for the development of nanoscaled therapeutic platforms. Amongst various nanocarriers, mesoporous silica nanoparticles (MSNs) is one of the most developed and promising inorganic materials-based drug delivery system for clinical translations due to their simple composition and nanoporous structure. MSNs possess unique structural features, for example, well-defined morphology, large surface areas, uniform size, controllable structure, flexible pore volume, tunable pore sizes, extraordinarily high loading efficiency, and excellent biocompatibility. Progress in structure control and functionalization may endow MSNs with functionalities that enable medical applications of these integrated nanoparticles such as molecularly targeted drug delivery, multicomponent synergistic therapy, in vivo imaging and therapeutic capability, on-demand/stimuli-responsive drug release, etc. In this chapter, the authors overview MSNs' characteristics and the scientific efforts developed till date involving drug delivery and biomedical applications.

查看原文本刊更多论文

介孔二氧化硅纳米颗粒

纳米技术与生物医学的结合为纳米级治疗平台的发展提供了巨大的机遇。在各种纳米载体中，介孔二氧化硅纳米颗粒(MSNs)由于其简单的组成和纳米孔结构，是目前最具发展前途的基于无机材料的临床转化给药系统之一。msn具有形态清晰、表面积大、尺寸均匀、结构可控、孔容灵活、孔径可调、负载效率极高、生物相容性优异等独特的结构特征。结构控制和功能化方面的进展可能赋予微纳米颗粒功能，使这些集成纳米颗粒能够应用于医学领域，如分子靶向药物递送、多组分协同治疗、体内成像和治疗能力、按需/刺激反应性药物释放等。在本章中，作者概述了msn的特点以及迄今为止在药物传递和生物医学应用方面所做的科学努力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials

自引率

0.00%

发文量