IOSR Journal of Dental and Medical Sciences最新文献

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Comparison of Fracture Resistance of Different Reattachment Techniues and Adhesive Materials on Incisal Tooth Fragment Reattachment 不同再附着技术及黏附材料在切牙碎片再附着中的抗折性比较
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-160603133138
Anshuka A. Agrawal, Saloni Agrawal, Devender Kumar Sharma, M. Bansal, Vipul Choudhary, K. Moolchandani
{"title":"Comparison of Fracture Resistance of Different Reattachment Techniues and Adhesive Materials on Incisal Tooth Fragment Reattachment","authors":"Anshuka A. Agrawal, Saloni Agrawal, Devender Kumar Sharma, M. Bansal, Vipul Choudhary, K. Moolchandani","doi":"10.9790/0853-160603133138","DOIUrl":"https://doi.org/10.9790/0853-160603133138","url":null,"abstract":"Purpose: This is an in vitro study to compare fracture resistance of different reattachment techniques and adhesive materials on incisal tooth fragment reattachment. Methodology: 100 sound human maxillary central incisors were selected .10 were maintained as a control group. Remaining 90 were divided randomly into 3 groups (n=30) based upon the materials used for reattachment and further divided into 3 subgroups (n=10) on the basis of different reattachment techniques. The materials used are dual cure resin cement, flowable composite, nano hybrid composite and three different reattachment techniques used were simple reattachment , overcontour and internal dentinal groove. Data was analyzed with ANOVA (One-Way) test and Post-Hoc Bonferroni test. Results: The control group had a significantly higher fracture resistance (p= 0.001); the highest fracture resistance values were obtained by Dual cure resin cement followed by Nano hybrid composite and minimum in Flowable composite .When compared between three different reattachment techniques internal dentinal groove showed the maximum fracture resistance followed by over contour technique and minimum showed the simple reattachment technique. Conclusion: Although, none of the tested materials provided fracture resistance similar to that found with the intact maxillary central incisors, utilizing the dual cure resin cement improved the fracture resistance of the reattached fragment than other materials.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"7 1","pages":"133-138"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76371681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Fixation of Subtrochantric Fractures Using Distal Femoral Locking Compression Plate of Contralateral Side 对侧股骨远端锁定加压钢板固定粗隆下骨折
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-1607013945
Roel Langshong, B. Punithavasanthan, Pheiroijam Bhupes, S. Singh, Rajkumar Debbarma, P. S. Prashanth, P. rai, Shams Gulrez, Dilip Soring, Temjen sunep
{"title":"Fixation of Subtrochantric Fractures Using Distal Femoral Locking Compression Plate of Contralateral Side","authors":"Roel Langshong, B. Punithavasanthan, Pheiroijam Bhupes, S. Singh, Rajkumar Debbarma, P. S. Prashanth, P. rai, Shams Gulrez, Dilip Soring, Temjen sunep","doi":"10.9790/0853-1607013945","DOIUrl":"https://doi.org/10.9790/0853-1607013945","url":null,"abstract":"Introduction: Different implants are available to internally fix subtrochantric fracture of femur, due to anatomical & biomechanical reasons, the sub-trochanteric femoral fracture still a challenge for Orthopaedic Surgeons Objective: The purpose of this study was to evaluate the outcome in early treatment of subtrochanteric fractures of femur with distal femoral locking compression plate of contralateral side. Methods: Thirty patients were included in this study. Sixteen patients (53.3%) had AO type 32B fracture, while nine patients (30%) and five patients (16.6%) were classified as AO type 32A and 32C respectively. Road traffic accidents accounted for 21 patients (70%). Mean follow-ups were 11 ±6 months (range 6 to 19 months). 27 fractures (90%) achieved union, average union time in 14.5 weeks Ranging from 10 weeks to 20 weeks. while three patients (10%) had complications. In one patient the plate had broken, one had broken screw and nonunion of the fracture. At the end of the follow-ups, 29 patients (96.6%) were community ambulators.The Modified Harris hip score (MMHS) was used to evaluate the functional outcome of surgery Conclusion: We conclude that distal femoral locking compression plate of contra lateral side is as effective as PF-LCP and is an effective alternative treatment for subtrochanteric fractures when properly performed.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"36 1","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89838271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis 牙龈炎和牙周炎患者唾液钙和钙素水平的改变
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-1607011719
A. Primasari, Yumi Lindawati, Irma Ervina
{"title":"Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis","authors":"A. Primasari, Yumi Lindawati, Irma Ervina","doi":"10.9790/0853-1607011719","DOIUrl":"https://doi.org/10.9790/0853-1607011719","url":null,"abstract":"‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"37 23","pages":"17-19"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91506143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cognitive impairment in patients with epilepsy: A case control study at a tertiary level hospital in India 癫痫患者的认知障碍:印度一家三级医院的病例对照研究
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-160702103106
Dr.Ravindra B. Narod, Dr.Rathod Rahul Narayanrao, Dr.Sayali V. Bhambar, Dr.Sapna Anjutagi, Dr.Smit U. Janrao, Dr.Pranav Deore
{"title":"Cognitive impairment in patients with epilepsy: A case control study at a tertiary level hospital in India","authors":"Dr.Ravindra B. Narod, Dr.Rathod Rahul Narayanrao, Dr.Sayali V. Bhambar, Dr.Sapna Anjutagi, Dr.Smit U. Janrao, Dr.Pranav Deore","doi":"10.9790/0853-160702103106","DOIUrl":"https://doi.org/10.9790/0853-160702103106","url":null,"abstract":"Introduction: Cognition is defined as the capacity of the brain to process information accurately leading to an adaptive behaviour. This study aims at understanding the decline in cognition in patients diagnosed with epilepsy in India using a standardized cognition scale. Methodology: We did a case control study in the Department of Psychiatry, Government Medical College, Miraj in which all patients with a diagnosis of epilepsy from October 2016 till February 2017 were included. Patients were tested for cognitive impairment using the PGI Memory scale (PGIMS). Controls were included from the population sample of non teaching staff of college. We noted age, gender, handedness, and education levels and clinical information. All cases and controls were tested for cognitive functioning using PGIMS. The data was analysed descriptively and then the cases and controls were compared using the unpaired Student’s t test, with p value less than 0.05 being statistically significant. Results:We enrolled 60 patients diagnosed with epilepsy and same number of healthy controls from the same insitution. Average age of the patients with epilepsy was 43.7±2.4 years and that of controls was 48.1±3.6 years. The difference between the cases and controls was found to be statistically highly significant in cognition tests like recent memory, remote memory, immediate recall and visual retention. On cognitive tests like attention and concentration, retention of dissimilar pairs, mental balance the difference between the groups was found to be statistically significant. Conclusions: Findings of our study demonstrates that patients with epilepsy shuould be routinely tested for cognitive decline.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"53 1","pages":"103-106"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85158917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Dengue Virus Infection Among Febrile Outpatients Attending University of Maiduguri Teaching Hospital in Borno State, Nigeria 尼日利亚博尔诺州迈杜古里大学教学医院发热门诊患者登革热病毒感染流行情况
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-160603155159
T. M. Hamisu, A. Yuguda, M. Abubakar, Y. Shettima, M. Maina, M. Y. Zanna, S. S. Baba, A. Andrew, i.C. Terhemen
{"title":"Prevalence of Dengue Virus Infection Among Febrile Outpatients Attending University of Maiduguri Teaching Hospital in Borno State, Nigeria","authors":"T. M. Hamisu, A. Yuguda, M. Abubakar, Y. Shettima, M. Maina, M. Y. Zanna, S. S. Baba, A. Andrew, i.C. Terhemen","doi":"10.9790/0853-160603155159","DOIUrl":"https://doi.org/10.9790/0853-160603155159","url":null,"abstract":"Dengue fever is a zoonotic arthropod-borne viral disease caused by Dengue fever virus (DENV) of the Genus Flavivirus and the FamilyFlaviviridaethat is endemic in Africa and beyond. The illness could be fatal especially among children and depleted patients.This study was designed to diagnose recentDengue virus infectionsamong febrile patients attending University of Maiduguri Teaching Hospital using ELISA kits for the detection of DENV IgM antibodies and NS1 antigens. Ninety one (91) venous blood samples were randomly collected from patients attending Maiduguri Teaching Hospital for malaria test between January and May, 2016. The samples were analysed using Enzyme Linked Immunosorbent Assays for dengue virus IgM antibodies (manufactured by Inverness Innovations Australia Pty Ltd ) and for Dengue virus NS1antigens (manufactured by Bio-Rad, France). The results showed a prevalence rate of 37.4% for DENV IgM antibodies and 9.9% for DENV NS1 antigens, with 3.3% of the subjects testingpositive for both IgM and NS1 antigen. Females were observed to have higher IgM prevalence rate of 41% and males showed higher NS1 antigen prevalence rate of 11.1%. The highest prevalence rate of 76.9% was recorded for IgM in the age bracket of 1-14 years. Samples from urban areas have the highest IgM antibodyprevalence rate of 41.4%, however, rural dwellers have the highest NS1 antigen prevalence rate of 11.3%. The presenting complaint with the highest IgM prevalence rate of 50% was headache + fever + nausea, while headache only had the highest NS1 antigen of 22.2%. The highest prevalence rate of 47.4% for IgM and 50% for NS1 antigen were recorded in March and May, 2016 respectively. This study therefore showed a high prevalence of IgM to Dengue fever virus indicating its circulation among febrile patients attending University of Maiduguri Teaching Hospital. Due to the probable misdiagnosis and subsequent treatment of dengue fever with other diseases such as malaria, dengue fever is shown to be prevalent in the study area. It is therefore recommended that febrile patients attending Maiduguri Teaching Hospital should be tested for dengue fever virus.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"28 1","pages":"155-159"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87755443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Case Report: Mandibular Second Premolar, A Morphological Ingruity 病例报告:下颌第二前磨牙,形态不完整
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-160603118120
Mridusmita Mukherjee, A. Bhattacharyya
{"title":"Case Report: Mandibular Second Premolar, A Morphological Ingruity","authors":"Mridusmita Mukherjee, A. Bhattacharyya","doi":"10.9790/0853-160603118120","DOIUrl":"https://doi.org/10.9790/0853-160603118120","url":null,"abstract":"The root canal is a complex system of finely tuned and synchronized small tributaries present along the body of tooth dentine. Therefore, knowledge of pulp anatomy is essential for endodontic treatment success, as lack of sound knowledge of the pulp anatomy can contribute to treatment failure. With the advancement of technological aids and numerous research have laid the foundation of multi rooted teeth or canals as the rule rather than exception. As such, bifurcating canals, multiple foramina, fins, deltas, loops, cul-de-sacs, C-shaped canals and accessory canals are commonly encountered in most teeth. So, accurate diagnosis followed by location, cleaning and shaping and finally obturation of such variations of canals is important as it determines the prospect of success of endodontic therapy.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"71 1","pages":"118-120"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83931612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient with Allergic Pathology: How to Handle It inDentistry. 过敏病理患者:如何处理。
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-1606036368
C. S. González, M. M. Corcuera, J. A. Durán, Melissa Rigesti Fertonani, Cécile Deschamps, Víctor Cortezo Vidal, Carmen Martín Carrera-Presas, L. A. D. L. Fuente, Víctor M . ParedesRodríguez
{"title":"Patient with Allergic Pathology: How to Handle It inDentistry.","authors":"C. S. González, M. M. Corcuera, J. A. Durán, Melissa Rigesti Fertonani, Cécile Deschamps, Víctor Cortezo Vidal, Carmen Martín Carrera-Presas, L. A. D. L. Fuente, Víctor M . ParedesRodríguez","doi":"10.9790/0853-1606036368","DOIUrl":"https://doi.org/10.9790/0853-1606036368","url":null,"abstract":"One of the most common medical emergencies that can occur in the appointment is an acute allergic reaction.The various forms of systemic allergicreactions are very well defined. These clinical situations are rarely described in the specialized literature and, in turn, poorly understood. Oral atopy comprises a wide variety of symptoms and signs sometimes difficult to differentiate from other adverse reactions. It is important to know the dental materials and other substances of stomatological use causing clinical diseases presented in oral mucosa; it corresponds to Stomatology Specialist his knowledge for diagnosis and successful treatment.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"14 1","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86851895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Clinico Histopathological Study of Childhood Leprosy 儿童麻风的临床组织病理学研究
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-1607018390
D. Rao, Dr.G. Leelavathi, Dr. G. Purnima
{"title":"A Clinico Histopathological Study of Childhood Leprosy","authors":"D. Rao, Dr.G. Leelavathi, Dr. G. Purnima","doi":"10.9790/0853-1607018390","DOIUrl":"https://doi.org/10.9790/0853-1607018390","url":null,"abstract":"Background: Leprosy is one of the oldest diseases known to mankind and is still associated with stigma. A high child proportion signifies active and recent transmission of the disease. Aim: To know the proportion of children in newly detected leprosy patients and their clinico histopathological categorisation. Methodology: This was a retrospective analysis of all leprosy patients less than 16 years of age registered at the Leprosy Clinic of GGH, Vijayawada from January2015-June2016. Results: Proportion of children among newly diagnosed leprosy patients was 9.2% .Majority of patients belonged to age group of 13 to 16 years(48%), with male preponderance. 24% patients gave family history of leprosy. 40% of patients belonged to PB type, 60% MB type. Slit skin smear was positive in 20%. According to clinical characteristics, majority of patients belonged to BT(52%) followed by TT(32%). According to histopathological characteristics majority of patients belonged to BT(48%) followed by TT(36%).Clinico Histopathological correlation in LL Hansen’s is 100%, in BT 76%.Type I reaction occurred in 2 patients(8%).Deformities were observed in 8% patients. Conclusion: Despite statistical elimination of leprosy, childhood leprosy still remains a public health problem. Early detection, treatment and contact tracing are important for reducing the burden of leprosy in the community.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"14 1","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79063761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Initiation of JE Vaccination-An Experience: A Mixed Method Study In A Tertiary Care Center of West Bengal, India 开始接种乙脑疫苗-经验:在印度西孟加拉邦三级保健中心的混合方法研究
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-1607012026
A. Samanta, DrJadav Chandra Sardar, P. Sengupta, A. Chatterjee, S. Lahiri
{"title":"Initiation of JE Vaccination-An Experience: A Mixed Method Study In A Tertiary Care Center of West Bengal, India","authors":"A. Samanta, DrJadav Chandra Sardar, P. Sengupta, A. Chatterjee, S. Lahiri","doi":"10.9790/0853-1607012026","DOIUrl":"https://doi.org/10.9790/0853-1607012026","url":null,"abstract":"Background:JE is an emerging public health problem in India.JE vaccine has been incorporated in the National Immunization Schedule in India following mass vaccination. Objectives:To explore the experiences gathered during mass vaccination period in a tertiary care center. Methodology:A mixed method approach consisting of a cross-sectional survey and qualitative study was adopted. The qualitative study was included to obtain more in-depth understanding of the experiences and perspectives of frontline workers and the team leader in form of in depth interview of LMO of satellite center and FGDamong all PHNS involved in the activity. Result:Among 2437 vaccinees surveyed, majority belonged to 1-5 years age group followed by 6-10 years.Only half of the caregivers of surveyed population knew the purpose of vaccination and 6%perceived that the vaccine prevents ‘Dengue’. No AEFI was reported during and one months following the mass vaccination.Qualitative approach revealed huge enthusiasm among the people about the vaccine, lack of staff and space to cater large age group section and inappropriate rush during the vaccination sessions and impairment of routine vaccination during the mass vaccination period. Conclusion:Thoroughly planned systematic IEC activities and prior deployment and orientation of staffs are pre requisites for conducting suchlarge scale mass vaccination programme.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"1 1","pages":"20-26"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83620294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation And Correlation of Insulin Resistance And Lipid Profile In Normal Pregnancy And Preeclampsia 正常妊娠和子痫前期胰岛素抵抗和血脂的评价及相关性
IOSR Journal of Dental and Medical Sciences Pub Date : 2017-07-01 DOI: 10.9790/0853-160603121125
Partiksha Partiksha, R. Bhatia, C. Vij, G. Bedi
{"title":"Evaluation And Correlation of Insulin Resistance And Lipid Profile In Normal Pregnancy And Preeclampsia","authors":"Partiksha Partiksha, R. Bhatia, C. Vij, G. Bedi","doi":"10.9790/0853-160603121125","DOIUrl":"https://doi.org/10.9790/0853-160603121125","url":null,"abstract":"Background: Preeclampsia syndrome is clinical spectrum of worsening disease with attenuated manifestations to cataclysmic deterioration, Life threatening for both mother and fetus. It affects 5-10% of all pregnancies & forms deadly triad with haemorrhage and infection being a direct cause of maternal mortality. Preeclampsia is associated with hyper insulinemia, increased insulin resistance which induces hypertriglyceridemia, endothelial dysfunction. It may lead to preeclampsia in genetically predisposed pregnant women. Association of high serum lipids with gestational protinuric hyerptension is highly suggestive of role for lipid profile analysis as diagnostic tool for preeclampisa. Aims & Objective: To evaluate and correlate fasting plasma insulin levels, insulin resistance and lipid profile in preeclampsia and normal pregnancy in ≥ 20 wks gestation. Material & methods: This is prospective observational study undertaken for one year on 40 pregnant women with preeclampsia and 25 normal pregnant women in tertiary care hospital in North India. Fasting plasma insulin levels, insulin resistance and lipid profile were evaluated in all 65 pregnant women in study and control group. Results: Mean age 26.±4.48 years, 25.0±2.79 years, mean period of gestation 32.38±2.53 wks, 29.48 ± 2.50 weeks in study & control group respectively were comparable. 52% patients in both the groups were primigravida. Mean fasting plasma insulin levels in study group i.e. 53.3 μIU/ml was significantly higher than, 16.35 μIU/ml in control group. Insulin resistance (HOMA IR index) in preeclampsia was 10.33, significantly high compared to 3.04 in normotensive pregnant women. Lipid profileserum cholesterol, triglycerides, HDL, LDL, VLDL were significantly raised in preeclampsia compared to control group. Conclusion: Highly significant increase in fasting plasma insulin levels, insulin resistance and lipid profile compared to normotensive pregnant females is a diagnostic tool for early diagnosis and management of preeclampsia step towards reducing maternal mortality and adverse fetal outcome.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"1 1","pages":"121-125"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83189063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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