Internet Journal of Medical Update - EJOURNAL最新文献_第3页

Case Report: Gastric diverticulum: an uncommon endoscopic finding in a case of halitosis 病例报告:胃憩室:一个罕见的内镜发现的病例口臭

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-05-15 DOI: 10.4314/IJMU.V13I1.5

Vipul D Yagnik

引用次数: 1

Lipemic serum: A quick clue to diagnose hyperlipidemic acute pancreatitis 血脂血清:诊断高脂血症急性胰腺炎的快速线索

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-05-15 DOI: 10.4314/IJMU.V13I1.6

Vipul D Yagnik, Vismit P. Joshipura

引用次数: 0

Correlation between hyperuricemia and lipid profile in untreated dyslipidemic patients 未经治疗的血脂异常患者高尿酸血症与血脂的相关性

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-05-15 DOI: 10.4314/IJMU.V13I1.2

S. Suneja, Rajani Kumawat, R. Saxena

{"title":"Correlation between hyperuricemia and lipid profile in untreated dyslipidemic patients","authors":"S. Suneja, Rajani Kumawat, R. Saxena","doi":"10.4314/IJMU.V13I1.2","DOIUrl":"https://doi.org/10.4314/IJMU.V13I1.2","url":null,"abstract":"There are a number of epidemiological studies that suggest the association of cardiovascular diseases and uric acid but very few studies highlight the direct association of deranged lipid profile with uric acid levels. The present study was indented to find out if any association exists between hyperuricemia and dyslipidemia. Blood samples were collected from healthy controls (n=70) and patients with dyslipidemia (n=70) who were not receiving any treatment for dyslipidemia. These samples were processed for estimating lipid profile and uric acid levels. The parameters in the two groups were compared. Correlation between different parameters was calculated by Pearson correlation analysis in both the groups. Uric acid levels (6.40 ± 1.27 vs 4.89 ± 0.21 mg/dl, P<0.001) were significantly higher in patients as compared to those in controls. There was significant increase in the levels of total cholesterol (TC), triglycerides (TAGs), LDL-C, VLDL-C, non-HDL cholesterol (P<0.001 in each case), in patients of dyslipidemia. However, significant decrease in the levels of HDL-C (P<0.001) was seen in patients compared to controls. LDL-C/HDL-C ratio (P<0.001), TC/HDL-C ratio (P<0.001) and TAG/HDL-C ratio (P<0.001) were also significantly increased in dyslipidemic subjects when compared to controls. Uric acid had significant correlations with TC (r=0.334, P<0.001), TAGs (r = 0.288, P<0.001), LDL-C (r = 0.241, P<0.001), VLDL-C (r= 0.158, P<0.001) and HDL-C (r= –0.652, P<0.001) in patients. Results of this study imply that there is higher association of hyperuricemia in dyslipidemic patients than normal subjects. Therefore treatment of underlying hyperuricemia should be an important aspect in planning the treatment strategy for dyslipidemia to reduce the cardiovascular morbidity. Keywords : Cardiovascular disease; Coronary artery disease; Dyslipidemia; Hyperuricemia; Lipid ratio","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90190555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Calcium homeostasis during pregnancy and lactation: role of vitamin D supplementation 孕期和哺乳期钙稳态:维生素D补充的作用

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-05-15 DOI: 10.4314/ijmu.v13i1.4

R. K. Marya

{"title":"Calcium homeostasis during pregnancy and lactation: role of vitamin D supplementation","authors":"R. K. Marya","doi":"10.4314/ijmu.v13i1.4","DOIUrl":"https://doi.org/10.4314/ijmu.v13i1.4","url":null,"abstract":"Pregnancy and lactation cycle is a period of considerable strain on maternal calcium homeostasis. A number of adaptive mechanisms involve increased intestinal calcium absorption, renal calcium conservation and changes in bone metabolism. These adaptations are mediated through changes in the secretion of various calciotropic hormones [1,25(OH)2 D3, parathormone, and calcitonin]. In all of these adaptive mechanisms, vitamin D is involved directly or indirectly. Now, it is being realized that not only darkskinned but also even Caucasian women tend to go into vitamin D deficiency during pregnancy. Adverse health outcomes such as preeclampsia, low birth-weight, neonatal hypocalcemia, poor postnatal growth, bone fragility, and increased incidence of autoimmune diseases have been linked to low vitamin D levels during pregnancy and infancy. Vitamin D deficiency seems to be a public health problem even in 2018. Most of the experts in the field are convinced that women need extra amounts of vitamin D during pregnancy and lactation. The amount of vitamin D that is required for optimum calcium homeostasis in this phase of life is still controversial. Studies are under way to establish the recommended daily doses of vitamin D in pregnant and lactating women. Key words : Vitamin D deficiency; Pregnancy; Lactation; Vitamin D supplementation","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"2010 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86315930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Case Report: Angiomyolipoma of the cervix – report of a rare entity 病例报告:子宫颈血管平滑肌脂肪瘤-罕见病例报告

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-02-23 DOI: 10.4314/IJMU.V12I2.4

N. Sarma, R. Srivastava, S. Agnihotri

引用次数: 1

Letter to the Editor: Myoepithelial carcinoma of the male breast 致编辑的信:男性乳房肌上皮癌

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-02-23 DOI: 10.4314/IJMU.V12I2.5

Vipul D Yagnik

引用次数: 0

Type II perforation of the body of the gallbladder in acalculous cholecystitis: a rare complication of enteric fever 无结石性胆囊炎胆囊体II型穿孔:肠热的罕见并发症

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-02-23 DOI: 10.4314/IJMU.V12I2.3

Vipul D Yagnik

引用次数: 3

A clinical study on etiology, prognosis, outcome and role of endoscopy in upper gastrointestinal bleed in a tertiary care center 三级医疗中心上消化道出血的病因、预后、结果及内镜作用的临床研究

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-02-23 DOI: 10.4314/IJMU.V12I2.2

Yash Shangavi, Jignesh B. Rathod, Vipul D Yagnik

{"title":"A clinical study on etiology, prognosis, outcome and role of endoscopy in upper gastrointestinal bleed in a tertiary care center","authors":"Yash Shangavi, Jignesh B. Rathod, Vipul D Yagnik","doi":"10.4314/IJMU.V12I2.2","DOIUrl":"https://doi.org/10.4314/IJMU.V12I2.2","url":null,"abstract":"Upper gastrointestinal bleed is defined as bleeding proximal to the ligament of Treitz. The aim of this study was to know the cause of upper GI bleed, prognosis of the patients and role of upper gastrointestinal endoscopy (UGIE) in the management of upper gastrointestinal bleed (UGIB). A study of 140 cases was carried out in the Shree Krishna Hospital and Pramukh Swami Medical College, Karamsad in India between January 2014 and June 2015. All patients were selected by the detailed history and physical examination. Patients with signs and symptoms suggestive of upper GI bleeding such as hematemesis, melena, blood in the nasogastric tubes, and profuse hematochezia were included in the study. Endoscopy was performed in all patients. Rockall scoring system was used to predict the mortality in patients with upper GI bleeding. We use descriptive statistics for analysis. It was found that upper GI bleed was more common in males than females, and was more prevalent in elderly individuals. The most common symptom was found to be hematemesis followed by abdominal pain. The most common cause was portal hypertension, which has a direct correlation with alcohol addiction. UGIE has both diagnostic as well as therapeutic role in UGIB. This study showed that upper GI bleeding was more common in male patients with the most common cause being portal hypertension. We observed that Mallory-Weiss tear had a particular association with NSAIDs. In our study, the Rockall scoring system was seen to predict the mortality in patients with upper GI bleeding. Endoscopy was both diagnostic and therapeutic and endoscopic variceal ligation (EVL/Glue) was performed for esophageal and/fundic varices and adrenaline injection for peptic ulcer bleeding and Mallory-Weiss tear. Keywords: Upper GI bleeding; Endoscopy; Endoscopic variceal ligation; Mallory- Weiss tear","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"23 1","pages":"4-9"},"PeriodicalIF":0.0,"publicationDate":"2018-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89510464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Editorial: Port-site infections due to non-tuberculous mycobacteria (atypical mycobacteria) in laparoscopic surgery 社论:腹腔镜手术中由非结核分枝杆菌(非典型分枝杆菌)引起的端口部位感染

Internet Journal of Medical Update - EJOURNAL Pub Date : 2018-02-23 DOI: 10.4314/ijmu.v12i2.1

Vipul D Yagnik

引用次数: 0

Chronic Allium sativum administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats 慢性给药可改变成年Wistar大鼠内侧前额叶皮层的自发交替和细胞结构

Internet Journal of Medical Update - EJOURNAL Pub Date : 2017-05-16 DOI: 10.4314/IJMU.V12I1.3

Ngozi Jane Muonagolu, Moses B. Ekong, Innocent A. Edgaha

{"title":"Chronic Allium sativum administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats","authors":"Ngozi Jane Muonagolu, Moses B. Ekong, Innocent A. Edgaha","doi":"10.4314/IJMU.V12I1.3","DOIUrl":"https://doi.org/10.4314/IJMU.V12I1.3","url":null,"abstract":"Intake of herbs and some of their constituents is reported to reduce risks of some diseases, with Allium sativum being one of such. This study was conducted to investigate the effects of Allium sativum extract on the medial prefrontal cortex and neurobehaviour of adult Wistar rats. Twenty-four male Wistar rats were divided into 4 groups (n = 6). Group 1 was the control and received distilled water placebo orally, while groups 2-4 received oral doses of 78 mg/kg, 156 mg/kg and 312 mg/kg Allium sativum extract for 28 days. On day 29, spontaneous alternation behavioural test was carried out, and immediately the rats were anaesthetized (50 mg/kg ketamine hydrochloride IP.) and perfusion-fixed with 10% buffered formalin. The whole brains were removed and the medial prefrontal cortex excised and processed for histomorphologic studies by haematoxylin and eosin, and cresyl fast violet techniques. Neurobehavioural test revealed less spontaneous alternation in 156 mg/kg Allium sativum group, while the prefrontal cortices of the test groups showed hypertrophy, hyperplasia, pyknosis, karyorrhexis, chromatolysis, loss of brain cellular membranes and Nissl substance. The 156 mg/kg Allium sativum group showed altered spontaneous alternation, while cellular pathologic changes were observed in the medial prefrontal cortex of these test groups in a dose dependent sequence. Keywords: Allium sativum ; Medial prefrontal cortex; Neurobehaviour; Histomorphology; Wistar rat","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"16 1","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2017-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78127733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0