Internet Journal of Medical Update - EJOURNAL最新文献

{"title":"The possible protective effect of Panax ginseng on experimentally induced colchicine myopathy in adult male albino rats: A histological study","authors":"Aiman Al-Maathadi, S. Farhan, Jihad A. M. Alzyoud, Aiman Al-Qtaitata","doi":"10.4314/ijmu.v14i1.3","DOIUrl":"https://doi.org/10.4314/ijmu.v14i1.3","url":null,"abstract":"Myopathy is one of the side effects of colchicine, manifested as pain, dysfunction, and weakness of muscles. Ginseng extract antioxidant  and anti-inflammatory activities have been reported in muscular tissue. This study was conducted to investigate whether administration of ginseng ameliorates colchicine-induced skeletal muscles damage in adult male albino rats. Forty adult male albino rats were randomly  divided into four groups (ten/group) – Group I (control group): rats received normal diet and orally given normal saline, Group II: ginseng extract was administered via oral gavage daily for one month at the doses of 300 mg/kg, Group III (Colchicine treated group): rats were  given colchicine (50 μg/kg/day) via oral gavage for one month, and Group IV: concomitant administration of Ginseng and colchicine for one month. Serum creatine kinase (CK) levels were measured, and skeletal muscles specimens were processed for light and electron microscopic examination. Administration of colchicine (group III) showed elevated serum CK, and histologically myofibrillar disarray foci together with cellular infiltration and edema. Group IV showed reduction in most of those manifestations. Concomitant administration of ginseng with colchicine ameliorated most of the symptoms related to colchicine induced-myopathy.","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81677958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seasonality in hyperglycemic emergencies in a Health Facility in Sub-Saharan Africa: The roles of geographic location, infection, and knowledge of diabetes mellitus status","authors":"O. H. Chijioke, Ogochukwu Y. Nwanne, David Samuel Olorunfemi, S. Chinenye","doi":"10.4314/ijmu.v14i2.4","DOIUrl":"https://doi.org/10.4314/ijmu.v14i2.4","url":null,"abstract":"Hyperglycemic emergencies (HEs) are acute complications of diabetes mellitus and they carry high morbidity and mortality. Studies have reported a seasonal pattern in the frequency of occurrence of both types 1 and 2 diabetes mellitus and even Gestational Diabetes Mellitus. No such association has been suggested for HEs. The study was conducted at the Asokoro District Hospital, Located in Abuja, Nigeria to examine a seasonal pattern in the frequency of hyperglycemic emergencies. The initial observation of an obvious fluctuation in the number of admitted cases of hyperglycemic emergencies motivated this prospective study which ran for a period of six years. It involved collecting the relevant information using a questionnaire from all HEs patients admitted to the medical ward from the first of January, 2008 to the 31st of December, 2013. Required investigations were done. The precipitating factors for HEs were looked for. The number of cases per month was noted for each year. The Statistical package used for analysis was STATA version 11. Round the year Abuja Climatic changes were monitored on the website of the Nigerian Meteorological station. Four hundred and fifty-one (451) patients with hyperglycemic emergency were enrolled for this study. Most of the patients, (55%), were in the middle-age bracket. Fifty-six per cent (56%), were not previously known to be living with diabetes mellitus. Infections, particularly of the respiratory and gastrointestinal tracks, were the commonest precipitating factors. Variation in the frequency of HEs was observed, with two peaks: one in April and a smaller peak in December. There is seasonal variation in the frequency of presentation of Hyperglycemic emergencies. This may have been influenced by exogenous factors such as geographic location, infection, and the fact that most of the patients never knew they had diabetes mellitus.","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86279937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroendocrine tumor of the hepatic flexure: a rare colonic tumor","authors":"Vipul D Yagnik, Sunil R Prajapati","doi":"10.4314/ijmu.v13i2.4","DOIUrl":"https://doi.org/10.4314/ijmu.v13i2.4","url":null,"abstract":"Neuroendocrine tumors (NETs) are rare, particularly common in the rectum. NETs of the colon (not including the appendix and rectum) are most commonly found in the cecum, and hepatic flexure involvement is rather infrequent. The clinical presentation of colonic NETs is dependent on the primary site. Many are discovered either at the time of screening or during the investigation of abdominal pain or anemia. Here we present a challenging case of a hepatic flexure colonic NETS of 26 -year-old male treated by laparoscopic right hemicolectomy. Keywords: Neuroendocrine tumors; Colonoscopy; Surgery; Immunohistochemical test","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"C-25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84428204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Book Review: Fundamentals of Operative Surgery, 2nd edition","authors":"S. Hindocha","doi":"10.4314/ijmu.v13i2.6","DOIUrl":"https://doi.org/10.4314/ijmu.v13i2.6","url":null,"abstract":"Book Title: Fundamentals of Operative SurgeryBook Author: Vipul YagnikPublisher: Wolters Kluwer, Year 2019, 435 pages Format: PDF and EPUB, Hardcover ISBN 9789387506817.","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76208023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Beyond the Numbers. What determines journal quality?","authors":"S. Dawka","doi":"10.4314/IJMU.V13I2.1","DOIUrl":"https://doi.org/10.4314/IJMU.V13I2.1","url":null,"abstract":"","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75566263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selfmonitoring of blood glucose practices by people living with diabetes who use their personal glucometers in Port Harcourt, Niger Delta Region, Nigeria","authors":"M. Nkpozi, A. Jumbo, N. Unamba, C. Unachukwu, S. Chinenye","doi":"10.4314/IJMU.V13I2.2","DOIUrl":"https://doi.org/10.4314/IJMU.V13I2.2","url":null,"abstract":"Self-monitoring of blood glucose (SMBG) assists persons living with diabetes with the day-to-day behavioral and therapeutic adjustments to their diabetes care. It is a cheaper and more available alternative to glycated haemoglobin (HbA1c) in Nigeria for monitoring glycaemic control. Information on SMBG practices of Nigerians living with diabetes using their personal glucometers is scanty. The aim of the study is to assess the intensity and frequency of SMBG by glucometer owners, and the extent the patients and/or the health care providers (HCP) utilize SMBG to achieve personalized treatment goals via behavioral/treatment adjustments. This was a cross sectional study carried out among persons living with diabetes that accessed diabetes care at the diabetes clinic of the University of Port Harcourt Teaching Hospital (UPTH) and using their personal glucometers. They were consecutively recruited. Data obtained by using intervieweradministered questionnaires were analyzed using SPSS version 20.0, and pvalue <0.05 was considered significant. A total of 128 persons living with diabetes participated in the study of which 40 (31%) were males and 88 (69%) were females; the mean age of the subjects was 52.05 ± 11.24 years with a range of 26–70 years. The majority of the study subjects (72%) were in the active working age group (25–60years). The highest frequency of glucometer use was in the 26 subjects (20%) who checked their blood glucose every morning while 62 (48%) of the subjects checked their blood glucose any morning they felt like. Most of the subjects (60%) did not have any recording device. Glucometer owners were not just the insulin-requiring people living with diabetes as more than half of the subjects, 66 (52%) were on oral anti diabetic drugs (OAD) only. Glucometer ownership was mainly by those that were in the working age group. SMBG protocol (frequency) was variable and SMBG data were not maximally utilized. Keywords: Self-monitoring of blood glucose; Personal glucometer; Diabetes; Blood glucose","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"17 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79270061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Editor: Sister Mary Joseph’s Nodule: A short compilation","authors":"S. Ergen","doi":"10.4314/IJMU.V13I2.5","DOIUrl":"https://doi.org/10.4314/IJMU.V13I2.5","url":null,"abstract":"","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"1095 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76729360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional status and its associated factors in Nigerian adults with serious mental illnesses","authors":"S. Osasona, O. Akanni","doi":"10.4314/ijmu.v13i2.3","DOIUrl":"https://doi.org/10.4314/ijmu.v13i2.3","url":null,"abstract":"Patients with serious mental illness may be less likely to achieve functional goals than the general population. Assessment of the functional impact of the illness is useful to determine severity of illness, evaluate remission, and achieve optimal treatment success. The aims of this study are to determine and compare the prevalence of low functional status among outpatients with major axis 1 psychiatric disorders, assess the risk factors for low functional status, and determine the proportion of the variance in low functional status explained by low self-esteem and non-adherence to medication. A descriptive cross-sectional study was conducted among 308 outpatients of the psychiatric unit of a tertiary hospital. The Global Assessment of Functions (GAF), Morisky Medication Adherence Scale (MMAS-8) and the Rosenberg’s Self-esteem Scale were used to collect data, which were analyzed using version 20 of SPSS. Level of statistical significance was set at 5% (P< 0.05). The overall prevalence of low functional status was 40.6%. Patients with schizophrenia had the highest prevalence of low functional status (53.4%). Educational attainment, employment status, self-esteem, medication adherence, and comorbidity had significant association with functional status. Poor medication adherence had the largest relative contribution (35.4%) to the variance in functional status, while self-esteem had an insignificant relative contribution of 3.4%. An appreciable proportion of the patients in this study had low functional status with more schizophrenic patients having impairment than patients with mood disorders. Poor medication adherence, among other variables, contributes significantly to low functional status. Physicians should give as much attention to functional recovery as they give to symptom resolution in the management of psychiatric patients. Keywords: Functional capacity; Psychiatric patient; Correlates; Benin-City","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84522520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of cleft lip and palate in Brazilian children 2011 - 2015","authors":"N. Andrade, T. Fernandes, E. Catão, Gustavo Correia Basto da Silva, L. Fernandes, Alidianne Fábia Cabral Cavalcanti, A. Cavalcanti","doi":"10.4314/IJMU.V13I1.3","DOIUrl":"https://doi.org/10.4314/IJMU.V13I1.3","url":null,"abstract":"Cleft lip and cleft palate are birth defects of complex etiology. The aim of this study was to evaluate the occurrence of cleft lip and palate in Brazilian children. An ecological and descriptive study, based on data from the Live Birth Information System (SINASC / DATASUS) between years 2011 and 2015 in the cities of Joao Pessoa, Campina Grande, Patos, Cajazeiras, and Sousa (State of Paraiba) was developed. Information on the presence of congenital anomalies and cleft lip and palate, gender of neonate, birth-weight (<2.5kg and ≥2.5kg) and mother's age were collected. Data were tabulated with Microsoft Excel software and presented through descriptive statistics (absolute and percentage distributions). In the study period, there were 206367 cases of live birth, with 1916 cases of children with congenital anomalies of which 109 (5.7%) had cleft lip and palate, predominantly males (66%). Regarding birth-weight, 27.5% had <2.5kg. The majority of mothers aged 20-29 years (45.9%). The city of Campina Grande concentrated the highest number of cases (50.5%), with prevalence of 7.36 cases per ten thousand live births. The frequency of cleft lip and palate was 5.2 per 10000 live births. Male children with normal birth-weight are the most affected by cleft lip and palate. Key words : Epidemiology; Cleft Lip; Cleft Palate; Congenital Abnormalities","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76867984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Small group teaching and learning","authors":"A. Agnihotri, Trevor Ngorosha","doi":"10.4314/IJMU.V13I1.1","DOIUrl":"https://doi.org/10.4314/IJMU.V13I1.1","url":null,"abstract":"","PeriodicalId":14472,"journal":{"name":"Internet Journal of Medical Update - EJOURNAL","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78370436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}