International Journal of Technology Assessment in Health Care最新文献

{"title":"Frameworks for assessing digital health technologies: a scoping review.","authors":"Hendrikje Rödiger, Laura Franziska Marie Wittich, Reinhard Jeindl, Yui Hidaka, Dionne Bowie, Juan Carlos Rejón-Parrilla, Zoe Garrett, Reinhard Busse, Cornelia Henschke","doi":"10.1017/S0266462326103523","DOIUrl":"10.1017/S0266462326103523","url":null,"abstract":"<p><strong>Objectives: </strong>The rapid evolution of digital health technologies (DHTs) presents distinct challenges for health technology assessment (HTA). Existing HTA frameworks, largely designed for conventional health interventions, may not sufficiently address these unique complexities. This scoping review provides an overview of existing assessment frameworks for DHTs, analyzing their purpose and the guidance they offer within the domains of the EUnetHTA Core Model.</p><p><strong>Methods: </strong>The review followed the Joanna Briggs Institute methodology and PRISMA-ScR guidelines. The literature was identified through searches in PubMed and Embase, covering publications from 2015 to 2024 in English or German, and was complemented by a manual hand search. The studies were screened and analyzed using Covidence, with data categorized inductively based on the EUnetHTA Core Model domains.</p><p><strong>Results: </strong>Of 3,576 screened records, 15 met inclusion criteria; an additional 45 frameworks were identified through hand searching, resulting in a total of 60 frameworks. Most frameworks focused on digital health applications (68 percent), while only a few addressed technologies such as artificial intelligence (2 percent). The frameworks primarily provide guidance on assessment, with varying focus on evidence requirements. The domains of the EUnetHTA Core Model were variably represented across the frameworks. Technical characteristics were most frequently addressed, while ethical, legal, and organizational domains received limited attention.</p><p><strong>Conclusions: </strong>This review highlights the diversity of existing frameworks for DHT assessment. This emphasizes the potential relevance of a future standardized framework that contains explanations of the methodological approach to the assessment of DHTs and is modularly customizable depending on the type of technology.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":"42 1","pages":"e24"},"PeriodicalIF":3.0,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organizational impact in healthcare in France: a decade of insights but chicken and egg situation.","authors":"Tess Martin, Giovanny Arbelaez-Garces, Christophe Roussel, Nicolas Martelli, Olivier Marcellin","doi":"10.1017/S026646232610347X","DOIUrl":"10.1017/S026646232610347X","url":null,"abstract":"<p><strong>Objectives: </strong>Over the past decade, organizational impact (OI) has gained recognition as a key dimension in health technology assessment (HTA) in France, particularly for medical devices. Despite the publication of a national framework by the Haute Autorité de Santé in 2020, the absence of standardized methodologies continues to hinder its integration into decision making.</p><p><strong>Methods: </strong>This commentary article traces the evolution of OI in French HTA, highlights real-world examples, and analyzes existing methodological tools, many adapted from other disciplines, that could enhance OI assessment.</p><p><strong>Results: </strong>It emphasizes the need for flexible, context-sensitive approaches and proposes recommendations to improve the robustness, reproducibility, and relevance of OI evaluations.</p><p><strong>Conclusions: </strong>The article also explores the implications for pricing and reimbursement decisions, as well as hospital-based HTA practices, aiming to support more structured and evidence-informed integration of organizational considerations into HTA processes in France and beyond.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":"42 1","pages":"e25"},"PeriodicalIF":3.0,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12979018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient involvement in health technology assessment: a new process in Singapore.","authors":"Ping-Tee Tan, Fiona Pearce, Kiah Shen Quek, Sok Huang Teo, Jen Hun Koh","doi":"10.1017/S0266462326103584","DOIUrl":"10.1017/S0266462326103584","url":null,"abstract":"<p><strong>Objectives: </strong>Patient involvement is recognized as an integral component of health technology assessment (HTA), with patients' lived experiences offering valuable insights that enhance the relevance, transparency, and quality of healthcare decision-making. In line with a national shift toward patient-centered care, Singapore's Agency for Care Effectiveness (ACE) established formal processes for patient involvement in HTA in 2021. This paper describes ACE's structured approach to identifying relevant patient organizations, co-developing processes, and building capacity to support meaningful patient input.</p><p><strong>Methods: </strong>A stakeholder mapping exercise was undertaken to identify relevant local patient and volunteer organizations by searching the Singapore Charity Portal, hospital websites, search engines, and social media platforms. Identified organizations were screened against predefined criteria and contacted to determine their interest in ACE's work. A process and methods guide, including survey templates, plain language materials, and training resources were co-developed with local patient organizations, drawing on international best practices, contextualized to local patients' needs.</p><p><strong>Results: </strong>ACE identified 106 patient organizations across 20 health conditions. During a pilot initiative between August and December 2022, 82 patients from 10 organizations provided input into 7 HTAs. Sustained participation continued afterwards, with patient testimonials submitted for 85 percent of HTAs in the first year, increasing to 89 percent in the second year.</p><p><strong>Conclusions: </strong>ACE's patient involvement processes have improved the relevance and acceptance of HTA recommendations. Ongoing engagement with patient organizations, systematic evaluation of impact, and refinement of processes will be crucial to ensure that patient input continues to inform and advance healthcare decision-making in Singapore.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e36"},"PeriodicalIF":3.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trust, validation, and accountability: implementing uses of generative artificial intelligence into Health Technology Assessment practice.","authors":"Rachael Fleurence, Jagpreet Chhatwal","doi":"10.1017/S0266462326103638","DOIUrl":"10.1017/S0266462326103638","url":null,"abstract":"<p><p>The 2025 HTAi Global Policy Forum (GPF) report offers a timely and thoughtful synthesis of the opportunities and challenges associated with the use of artificial intelligence (AI), and particularly generative AI (GenAI), in Health Technology Assessment (HTA) (1). Its emphasis on trust, human agency, and risk-based approaches reflects both the maturity of the discussion within the HTA community and a shared recognition that technical capability alone is insufficient for responsible adoption. The report succeeds in articulating a common set of principles and a broadly aligned vision across HTA bodies, life sciences, and other interest holders.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e41"},"PeriodicalIF":3.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two decades of impact: lessons from the HTAi Patient and Citizen Involvement in HTA Interest Group.","authors":"Aline Silveira Silva, Fiona Pearce, Karen M Facey, Neil Bertelsen, Janet Wale, Anke-Peggy Holtorf, Ann Single","doi":"10.1017/S0266462326103651","DOIUrl":"10.1017/S0266462326103651","url":null,"abstract":"<p><p>Since its establishment in 2005, the HTAi Patient and Citizen Involvement in HTA Interest Group (PCIG) has worked to strengthen health technology assessment (HTA) by systematically incorporating patient and citizen perspectives. Over two decades, PCIG has advanced this goal through multistakeholder projects and collaborations that have produced practical tools, guidance, and methods to support patient involvement in HTA worldwide. Through global knowledge exchange, PCIG has fostered shared learning and capacity building for inclusive, participatory HTA. Its work continues to drive a shift in the mindset of the HTA community - from passive consultation to active partnership with patients and citizens - and encourages investment in robust research to understand patient perspectives. As health systems increasingly aim to reflect lived experiences and community values to improve the implementation and impact of services, PCIG's journey offers a compelling example of the long-term value of collective action, sustained engagement, and meaningful involvement in HTA.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e32"},"PeriodicalIF":3.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What do HTA agencies need for generating health-related quality of life evidence? Findings from a global survey.","authors":"Annushiah Vasan Thakumar, Paula Lorgelly, Louise Longworth, Lucila Rey-Ares, Fredrick Purba, Dominik Golicki, Federico Augustovski, Kim Rand, Rosalie Viney, Nick Bansback, Nan Luo","doi":"10.1017/S0266462326103602","DOIUrl":"10.1017/S0266462326103602","url":null,"abstract":"<p><strong>Objectives: </strong>The overall aim is to understand the practices, views, and needs of health technology assessment (HTA) practitioners worldwide regarding the use of health-related quality of life (HRQoL) data for generating cost-effectiveness evidence.</p><p><strong>Methods: </strong>We invited HTA practitioners in sixty countries to complete an online survey on their perspectives on the measurement and valuation of health. We performed descriptive analyses of the overall sample, examined response differences across six regions, and pooled responses to open-ended questions for content analysis.</p><p><strong>Results: </strong>A total of 238 individuals from 45 countries completed the survey, with a mean response number per country of 5.28 (SD: 4.45). Most responses came from public sector employees (seventy-two percent), and ninety percent were involved in cost-effectiveness-related work. The top three most frequently used utility instruments were EQ-5D, SF-6D, and EQ-5D-Y, and the elicitation methods were time trade-off, visual analogue scale, and standard gamble. Health-state preferences of the general public from another country were more frequently used than the preferences of the local public. Common data quality issues were poor sample representativeness and a small sample size of utility data. In Asia and Western Europe, the top-voted research priority was developing utility instruments that capture both healthcare and social care impact. In four regions, developing utility instruments for children was the second-highest research priority.</p><p><strong>Conclusions: </strong>The survey addressed important knowledge gaps regarding current practices in measuring and valuing HRQoL in HTA and provided insights into HTA practitioners' views on instruments, methods, and data-related challenges and needs for generating HRQoL evidence.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e33"},"PeriodicalIF":3.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147306095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level of health technology assessment process-related skills among doctors in Croatia: a cross-sectional survey study.","authors":"Miro Vuković, Mirjana Huić, Ljubo Znaor, Željko Krznarić, Ana Marušić","doi":"10.1017/S0266462326103572","DOIUrl":"10.1017/S0266462326103572","url":null,"abstract":"<p><strong>Introduction: </strong>The European Union's Health Technology Assessment Regulation (HTAR) and its implementing acts foresee various forms of clinician involvement, such as joint clinical assessment or Joint Scientific Consultation. However, considering the varying preparedness levels for HTAR, as well as the understanding of the health technology assessment (HTA) principles and processes, this study aimed to evaluate the levels of HTA-related skills among medical and dental doctors in Croatia.</p><p><strong>Methods: </strong>A cross-sectional survey study was conducted among medical and dental medicine doctors in Croatia. The survey recorded respondents' relevant experience with HTA processes along with skill levels across the entire HTA process, mainly for acting as individual clinical experts or on behalf of their professional organizations, as well as potential HTA doers. Skill levels were evaluated using a 5-point scale (1 - <i>no knowledge</i> to 5 - <i>full expertise</i>).</p><p><strong>Results: </strong>Among the 376 respondents included, only 6.1 percent had previous involvement in HTA, and 2.2 percent were familiar with HTAR. Related to the HTA process, the highest scores were observed in the understanding of key concepts and results of searching for studies, critical appraisal, study synthesis preparation, and ethics. The lowest scores were recorded in health economics, evidence grading, qualitative synthesis, and public/patient involvement. Respondents with prior research experience and those who reported frequent research use had significantly higher HTA skill scores.</p><p><strong>Conclusions: </strong>A significant gap in HTA-related skills highlights the need for targeted professional development programs and long-term educational reforms to build the capacity for various modes of involvement in HTA processes and their implementation.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e34"},"PeriodicalIF":3.0,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generative artificial intelligence in health technology assessment: a patient and citizen dialogue on trust, human oversight, and shared governance.","authors":"Fiona Pearce, Aline Silveira Silva","doi":"10.1017/S0266462326103560","DOIUrl":"10.1017/S0266462326103560","url":null,"abstract":"","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e21"},"PeriodicalIF":3.0,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early health technology assessment of a primary care tool for the diagnosis and management of headaches in Alberta, Canada.","authors":"Sarah Koles, Diepreye Ayabina, Sasha van Katwyk, Brian Chan, Charles Yan","doi":"10.1017/S0266462326103547","DOIUrl":"10.1017/S0266462326103547","url":null,"abstract":"<p><strong>Background: </strong>Lasoo Health is an e-software in the early stages of development, designed to generate a consult report with the most probable headache diagnosis and treatment plan from direct patient input. A patient accesses the program with their consent and a referral from primary care. Digital consult is then reviewed by a medical specialist and then sent to the primary care provider to initiate care. This early health technology assessment (eHTA) assesses the potential impact of Lasoo Health on timely access to effective headache management, cost savings, and health outcomes compared to the current standard of care (SOC) in Alberta, Canada.</p><p><strong>Methods: </strong>We developed a discrete event simulation (DES) of headache diagnostic pathways for Albertan patients suffering from headaches. The model was parameterized using secondary data sources identified via relevant published literature and subject matter expert opinion. Cost-effectiveness was expressed from a societal perspective using the incremental net monetary benefit (iNMB) of Lasoo Health incorporated with the SOC compared to SOC alone over an analytical time frame of five years.</p><p><strong>Results: </strong>Our analysis suggests that incorporating Lasoo Health into the SOC may reduce specialist assessment wait times by 70 percent and total per-patient costs by 7 percent. Using a willingness-to-pay (WTP) threshold of Canadian dollars (CAD) 50,000 (U.S. dollars (USD) $35,240), the iNMB per patient was estimated to be CAD 1,069 (USD $753).</p><p><strong>Conclusions: </strong>The benefits of implementing Lasoo Health over a 5-year period could translate to improved patient outcomes, reduced wait times for specialists, and lower productivity losses among headache patients.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e35"},"PeriodicalIF":3.0,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing an assessment tool to measure health equity considerations of guideline development handbooks.","authors":"Ramaa Chitale, Adam Richards, Precious Williams, Tari Turner, Stephanie Goodrick, Ana González Ramos, Christina McMillan Boyles, Deana Manassaram-Baptiste, Caleb Kimutai Sagam, Eleanor Ochodo, Rachel Kowalsky, Emily Smith","doi":"10.1017/S0266462326103559","DOIUrl":"10.1017/S0266462326103559","url":null,"abstract":"<p><strong>Objectives: </strong>Guideline development handbooks outline the methodology that authoring organizations use to create public health and clinical practice guidelines (CPGs). We created an Equity Assessment Tool (EquAT) for guideline development handbooks to identify areas of improvement and foster conversations.</p><p><strong>Methods: </strong>Sequential phases lead to tool development and face/content validation in this mixed-methods study. In phase 1, we reviewed the literature to generate a list of \"essential elements\" or tasks that are part of guideline development methodology, mapped \"essential elements\" with relevant equity concepts, and drafted our tool for use in reviewing guideline development handbooks. In phase 2, we surveyed experts for feedback on \"essential elements\" and explicit language for assessing equity within the tool and refined items. We piloted and finalized the tool based on feedback.</p><p><strong>Results: </strong>We identified 18 essential elements within five domains of guideline development and created a draft EquAT. Twenty of 25 invited experts responded to the online survey for feedback on the tool. Most experts provided limited feedback, and the most common suggestion was adding clarifying language to the existing tool criteria for assessing equity. Ten experts participated in pilot testing the revised tool. We found a diversity of scores, and potential reasons might be due to the complexity of the tool, differences in equity frameworks, and a variety of expertise. We incorporated their feedback and finalized the tool.</p><p><strong>Conclusions: </strong>We developed and validated the EquAT, a tool to foster discussion among assessors about the extent of health equity considerations in guideline development handbooks.</p>","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":" ","pages":"e28"},"PeriodicalIF":3.0,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}