International journal of scientific research最新文献_第7页

HISTOPATHOLOGICAL REVIEW AND RE-CATEGORIZATION OF THYROID MALIGNANCIES BASED ON WHO CLASSIFICATION OF ENDOCRINE TUMORS, 2022 组织病理学审查和根据谁的内分泌肿瘤分类对甲状腺恶性肿瘤重新分类，2022 年

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/8101528

Ganguly S, Singh Bp, Bhoi SR

{"title":"HISTOPATHOLOGICAL REVIEW AND RE-CATEGORIZATION OF THYROID MALIGNANCIES BASED ON WHO CLASSIFICATION OF ENDOCRINE TUMORS, 2022","authors":"Ganguly S, Singh Bp, Bhoi SR","doi":"10.36106/ijsr/8101528","DOIUrl":"https://doi.org/10.36106/ijsr/8101528","url":null,"abstract":"Thyroid cancer (TC) is the commonest endocrine malignant tumor whose incidence has been increasing steadily for decades in the world. This\u0000alarming rise in the incidence of thyroid malignancies, even in the face of low and stable and mortality rates is thought to be predominantly driven\u0000by overdiagnosis; notably evident in the case of papillary thyroid tumors. This has led to otherwise indolent tumors being aggressively managed\u0000causing potential harms to patients and levying unnecessary costs on an already overburdened healthcare system. The 5th edition of the World\u0000Health Organization (WHO) classication of endocrine tumors, released in 2022, has introduced several changes to the nomenclature, grading and\u0000prognostication of thyroid proliferations based on pathologic features and molecular prole that can help in improving risk stratication by\u0000categorizing tumors based on histological and molecular characteristics, thereby reducing the burden of diagnosis of incidental and indolent\u0000lesions, as well as de-escalate the treatment. The present study attempts to review the histopathological diagnosis of all previously reported thyroid\u0000neoplasms at our institution and reclassify them according to the recently updated criteria.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"14 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141051209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UNRAVELING THE ANATOMICAL COMPLEXITY: IMPLICATIONS OF GREAT SAPHENOUS VEIN VARIATIONS ON SURGICAL STRATEGIES 揭开解剖复杂性的面纱：大隐静脉变异对手术策略的影响

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/4601715

Rajasekhara Babu. G, Laxmi Durga Vuddi, Sagar Reddy. G, Ushanajali. V, Nithin Kumar M

{"title":"UNRAVELING THE ANATOMICAL COMPLEXITY: IMPLICATIONS OF GREAT SAPHENOUS VEIN VARIATIONS ON SURGICAL STRATEGIES","authors":"Rajasekhara Babu. G, Laxmi Durga Vuddi, Sagar Reddy. G, Ushanajali. V, Nithin Kumar M","doi":"10.36106/ijsr/4601715","DOIUrl":"https://doi.org/10.36106/ijsr/4601715","url":null,"abstract":"Varicosities of the great saphenous vein (GSV) and its tributaries pose a common medical concern affecting up to 25% of adults. Understanding the\u0000intricate anatomical variations and their correlation with the fascia lata of the thigh is paramount for clinical management. This study conducted\u0000dissections on forty cadaveric lower limbs to scrutinize these anatomical nuances. The fascia lata of the anterior thigh was found to bifurcate into\u0000the supercial saphenous fascia and the deep fascia lata proper, forming distinct saphenous compartments. Three types of saphenous compartments\u0000were delineated: Type 1, characterized by a triangular compartment accommodating the GSV and its tributaries (30%); Type 2, featuring a fascial\u0000canal housing the GSV(30%); and Type 3, displaying a small fascial saphenous compartment with variable boundaries containing the GSVand one\u0000or two of its tributaries (40%). The study also observed the number of supercial tributaries ranging from 3 to 7 with a mean of 5.12 ± 1.95, while the\u0000GSV length ranged from 5 to 8.5 cm with a mean of 6.43 ± 1.65 cm. Furthermore, the length of tributaries in the saphenous compartment varied\u0000from 2 to 6 cm with a mean of 3.82 ± 2.74 cm. Noteworthy ndings include the intimate association of the external pudendal artery (EPA) with the\u0000saphenofemoral junction (SFJ) in 30% of cases and the relationship between cutaneous branches of the femoral nerve with the GSV, its tributaries,\u0000and SFJ in 52.5% of cases. This intricate understanding of anatomical relationships is indispensable for devising precise surgical strategies to\u0000manage varicosities effectively","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141025725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EXPLORING ANTICANCER POTENTIAL OF CENTAUREA BEHEN L., ELAEOCARPUS GANITRUS ROXB, GLORIOSA SUPERBA L. AND FICUS RELIGIOSA L. AGAINST HUMAN LUNG CANCER (A-549) CELL LINES 探索仙人掌、皂荚、芒柄花和薜荔对人类肺癌（A-549）细胞株的抗癌潜力

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/3505321

Satnam Singh, Amandeep Kaur, R. G. Saini

{"title":"EXPLORING ANTICANCER POTENTIAL OF CENTAUREA BEHEN L., ELAEOCARPUS GANITRUS ROXB, GLORIOSA SUPERBA L. AND FICUS RELIGIOSA L. AGAINST HUMAN LUNG CANCER (A-549) CELL LINES","authors":"Satnam Singh, Amandeep Kaur, R. G. Saini","doi":"10.36106/ijsr/3505321","DOIUrl":"https://doi.org/10.36106/ijsr/3505321","url":null,"abstract":"Background: Phytochemicals form the basis of research and development of new molecules leading to the development of new novel drugs. In the\u0000oncology sector, plants have contributed more than 60% of the anti-cancer drugs, directly or indirectly. The present study Aims and Objectives:\u0000was conducted with the objective to explore the antitumor activity of various extracts obtained from dried roots of Centaurea behen L., dried\u0000fruits/beads of Elaeocarpus ganitrus Roxb., dried roots of Gloriosa superba L. and dried leaves of Ficus religiosa L. against human lung cancer\u0000(A 549) cell lines. Method: Phytoconstituents were extracted by Soxhlet method using hexane, chloroform, methanol and water as solvents. MTT\u0000assay was used to nd the anti-proliferative potential of these plant extracts. The trypan blue dye exclusion test was used to determine the number of\u0000viable cells present in a cell suspension. Cytotoxic activity was also evaluated against non-cancerous cell lines (MCF-10A). Results: On A-549 cell\u0000lines, 93% cell death was reported with G. superba aqueous extract followed by E. ganitrus methanol extract and F. religiosa hexane extract and\u0000C. behen aqueous extract with 87%, 81.61% and 75 % cell death respectively. However, none of the extracts showed cytotoxic effect upon\u0000testing against normal non-cancerous cell lines (MCF- 10A). Conclusions: The results of the current ndings prove that phytoconstituents present\u0000in these plant extracts have high anticancer potential. This study strongly suggests the possibility of medicinal plants as an important source of\u0000anticancer drug development.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"18 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A TRIAD TO DIAGNOSIS- CONGENITAL ADRENAL HYPERPLASIA 三联诊断--先天性肾上腺皮质增生症

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/6303485

Lakshmi Menon, Akshay Raundhal, Shriya Umalkar

引用次数: 0

A STUDY OF MENOPAUSAL SYMPTOMS USING THE MENOPAUSE RATING SCALE (MRS) IN THE RURAL WOMEN OF GURUGRAM DISTRICT OF HARYANA, NORTH INDIA 印度北部哈里亚纳邦古鲁格拉姆地区农村妇女使用更年期评分量表（Mrs）对更年期症状的研究

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/8901207

Jayati Nath, Nikita Ghanshyam Jain

引用次数: 0

AN OBSERVATIONAL STUDY ON INDICATIONS FOR PRIMARY CESAREAN SECTION AT A TERTIARY CARE CENTRE 关于一家三级医疗中心初次剖腹产适应症的观察研究

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/7804093

Sanjana Kurimella, Subhashini Revu, Ratna Manjula Songa, Siddhartha Kancharla, Karuna Guguloth

{"title":"AN OBSERVATIONAL STUDY ON INDICATIONS FOR PRIMARY CESAREAN SECTION AT A TERTIARY CARE CENTRE","authors":"Sanjana Kurimella, Subhashini Revu, Ratna Manjula Songa, Siddhartha Kancharla, Karuna Guguloth","doi":"10.36106/ijsr/7804093","DOIUrl":"https://doi.org/10.36106/ijsr/7804093","url":null,"abstract":"Background: Caesarean section is the most commonly performed obstetric surgical procedure which with a suitable indication is potentially\u0000lifesaving. But it has many disadvantages for both mother and baby. Aims and Objectives: Hence, the present study is taken up to analyze various\u0000indications of primary cesarean section in a tertiary hospital, with an aim to reduce the C-section rate. Material and Methods: This is a\u0000Retrospective Observational study conducted at GGH Guntur, a tertiary care center, for 1 year from 1st October 2022 to 30 September 2023. All\u0000primary cesarean sections done at GGH, Guntur during the study period were included. All Repeat cesarean sections, primary sections done in\u0000other hospitals and referred to GGH Guntur, and patients with a previous history of laparotomy done for any obstetric or gynecological cause were\u0000excluded. Results: During the study period, out of 7548 deliveries, Normal deliveries were 3591, whereas Total cesarean sections were 3957. Of\u0000them, 2148 were primary cesarean sections and 1809 were repeat cesarean sections. So, the rate of primary cesarean section in our hospital was\u000054.3%. Fetal distress (32%) was found to be the most common indication for primary c-section followed by Cephalo Pelvic Disproportion (CPD)\u0000(26%). Conclusion: Our study highlights the need to lower c-section rates. Efforts like counseling women about the benets of Normal Vaginal\u0000Delivery(NVD), precise use of partograph, judicious use of oxytocin with other labour-inducing agents, timely admission and wise decision\u0000making while considering c-section, and expertization of instrumental vaginal delivery skills should be taken to achieve this.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ENTEROCUTANEOUS FISTULA: PRESENTATION, TREATMENT MODALITIES, AND OUTCOMES IN 20 PATIENTS 肠瘘：20 名患者的表现、治疗方式和结果

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/8500465

Kasturi Bharadwaj, P V Dwarakanath Reddy

{"title":"ENTEROCUTANEOUS FISTULA: PRESENTATION, TREATMENT MODALITIES, AND OUTCOMES IN 20 PATIENTS","authors":"Kasturi Bharadwaj, P V Dwarakanath Reddy","doi":"10.36106/ijsr/8500465","DOIUrl":"https://doi.org/10.36106/ijsr/8500465","url":null,"abstract":"Background: Enterocutaneous stula (ECF) is a difcult condition managed in surgical wards and is associated with signicant morbidity and\u0000mortality. Sepsis, malnutrition, and electrolyte abnormality are the classical triad of complications of ECF. This study Aims & Objectives:\u0000explores different treatment modalities and outcomes in SUM Hospital. All consecutive patients who Materials And Methods: developed or\u0000presented with ECF during the study period were included. The etiology, anatomic distribution, stula output, clinical course, complications,\u0000predictive factors for spontaneous closure, and outcomes for patients with ECF were studied. A tota Results: l of 20 patients were included in this\u0000prospective observational study, of which 13 were males and 7 were females. About 90% of ECFs were postoperative. The ileum was found to be\u0000the most common site of ECF. Also, 50% of stulas were high and 50% were low. Serum albumin levels correlated signicantly with stula healing\u0000and mortality. Surgical intervention was required in 60% of patients. Conclusion: Most of the ECFs are encountered in the postoperative period.\u0000Serum albumin levels can predict stula healing and mortality. Conservative management should be the rst line of treatment. Mortality in patients\u0000with ECF continues to be signicant and is commonly related to malnutrition and sepsis. Timely surgical intervention signicantly improves the\u0000outcomes.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"148 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141028621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PERCEPTION OF EARLY CLINICAL EXPOSURE BY I MBBS STUDENTS 医学学士学生对早期临床接触的看法

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/2702256

Sunil Kumar Nanda, Ramachandran Thiruvengadam

{"title":"PERCEPTION OF EARLY CLINICAL EXPOSURE BY I MBBS STUDENTS","authors":"Sunil Kumar Nanda, Ramachandran Thiruvengadam","doi":"10.36106/ijsr/2702256","DOIUrl":"https://doi.org/10.36106/ijsr/2702256","url":null,"abstract":"Background: The National Medical Council (NMC) in its new educational reforms has made Early Clinical Exposure (ECE) sessions\u0000compulsory. Though it is being followed by all medical colleges, there are very few studies where perception of ECE in Biochemistry has been\u0000studied. Objectives: To determine the perception of I MBBS students about ECE in Biochemistry. Materials And Methods: Study design :\u0000Ambispective qualitative study, Study setting : Biochemistry Department. Subjects : I MBBS students 2022 Batch, Sampling technique :\u0000Purposive sampling, Study duration : 4 months. Retrospective component: ECE Reection questionnaire were given to all students after ECE\u0000sessions. We studied 120 ECE reections. Prospective component : We conducted Focused group discussion (FGD) and in-depth interviews\u0000(IDI) for 40 students. The Themes generated from reections, Focused group discussion (FGD) and in-depth interviews were analyzed. Results:\u0000Thematic analysis Themes on early clinical exposure sessions emerging from Focused group discussion (FGD) and in-depth interviews were :\u0000Understanding of ECE Method – “It was helpful and exposed us to different clinical conditions\", Impact on Clinical Problem-Solving - “By ECE\u0000sessions, we learnt how to encounter clinical cases\", Enhancements for ECE Sessions - “taking students to wards”, Diverse Learning Outcomes -\u0000“ECE sessions made complex manifestations into easily understandable topics\". Conclusion: There was a broad understanding of ECE and\u0000perceptual shift in study topics among participants. Integration of basic sciences with clinical subjects was found benecial, though complexities\u0000were noted. Suggestions for ECE enhancements were more interactive sessions and real-life clinical exposure.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"47 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141043226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SUBCUTANEOUS FAT SUTURE IN CESAREAN SECTIONS AND WOUND DISRUPTION 剖腹产中的皮下脂肪缝合和伤口破坏

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/0520762

Nahla Hatam Hamodi

{"title":"SUBCUTANEOUS FAT SUTURE IN CESAREAN SECTIONS AND WOUND DISRUPTION","authors":"Nahla Hatam Hamodi","doi":"10.36106/ijsr/0520762","DOIUrl":"https://doi.org/10.36106/ijsr/0520762","url":null,"abstract":"Background: Cesarean sections, which are performed either elective or as an emergency, have become a common procedure in obstetrics.\u0000Although there are many advantages of this procedure for the baby as well as for the mother in apt situations, there are many risks associated with it.\u0000Wound infection, or disruption is a common complication following caesarean section. The factors inuencing the risk of these complications are\u0000many but maternal obesity, an increase in the subcutaneous fat, and its closure after the procedure are the main risk factors. Since there are no basic\u0000recommendations regarding suturing, the type of suture materials to be used, etc., the procedure varies among the practitioners, and hence the\u0000complications after the procedure. Thus, in this article, the effects of suturing the subcutaneous fat in cesarean sections on wound disruption are\u0000reviewed and the current status of the choice of suture materials to be used is also considered. Conclusion:There are no strong shreds of evidence to\u0000prove the inuence of suturing the subcutaneous fat or the type of suture material used on wound disruption during cesarean section. Most of the\u0000authors agree with the fact that closure of the subcutaneous fat reduces the risk of wound disruption for subcutaneous tissue larger than 2 cm","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141145553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ATTITUDE TOWARDS MENTAL ILLNESS, SENSE OF COMMUNITY, SELFCOMPASSION AND HELP-SEEKING ATTITUDE - A COMPARATIVE STUDY 对精神病的态度、群体意识、自我同情和求助态度--一项比较研究

International journal of scientific research Pub Date : 2024-05-01 DOI: 10.36106/ijsr/2603110

Sushmitha Subramani

{"title":"ATTITUDE TOWARDS MENTAL ILLNESS, SENSE OF COMMUNITY, SELFCOMPASSION AND HELP-SEEKING ATTITUDE - A COMPARATIVE STUDY","authors":"Sushmitha Subramani","doi":"10.36106/ijsr/2603110","DOIUrl":"https://doi.org/10.36106/ijsr/2603110","url":null,"abstract":"Background: Most studies that have explored sense of community (SOC), attitude towards mental illness (AMI), self-compassion (SC), and\u0000attitude towards seeking professional help (ATSPH), have studied them individually in one sample population only without taking into\u0000consideration the geographical variations.Method: The comparative study used the ex-post facto research design and the mixed-method\u0000explanatory sequential design to understand the effect of SOC and AMI on SC and ATSPH while comparing University students (n=124) from 2\u0000Indian states Uttar Pradesh and Gujarat. Results: The data from Lucknow and Vadodara were compared, SOC had no signicant effect on SC and\u0000ATSPH, but AMI had a signicant effect on SC and ATSPH. The qualitative study exploring AMI in Lucknow sample from Media department\u0000(n=10) highlighted three themes- reactions, causes and cures. The sub-themes of 'reactions' were sympathy, shock, and agony. The sub-themes of\u0000'causes' were environmental factors, emotional factors, adverse experiences, and biological factors. The sub-themes of 'cures' were environment,\u0000pleasurable activities, care, medications, love, sympathy, and togetherness.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"11 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141024264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0