International journal of oral and maxillofacial surgery最新文献

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Development and validation of a predictive scoring system for excessive intraoperative blood loss in orthognathic surgery 正颌手术术中失血过多的预测评分系统的开发和验证。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-05-30 DOI: 10.1016/j.ijom.2025.05.007
B. Kampeera , N. Sriyaranya , Y. Aschaitrakool , W. Powcharoen
{"title":"Development and validation of a predictive scoring system for excessive intraoperative blood loss in orthognathic surgery","authors":"B. Kampeera ,&nbsp;N. Sriyaranya ,&nbsp;Y. Aschaitrakool ,&nbsp;W. Powcharoen","doi":"10.1016/j.ijom.2025.05.007","DOIUrl":"10.1016/j.ijom.2025.05.007","url":null,"abstract":"<div><div><span>Risk stratification<span> for excessive bleeding prior to orthognathic surgery is necessary for optimizing </span></span>patient safety<span><span> and enhancing postoperative recovery<span><span>. The aim of this study was to develop and validate a simplified scoring system for predicting excessive intraoperative blood loss (IBL) during orthognathic surgery. This retrospective cohort study included 361 patients who underwent orthognathic surgery. Factors related to excessive IBL were analysed. The candidate predictors for excessive IBL were determined by </span>logistic regression analysis. The performance of the model was assessed through its discrimination ability and a calibration plot. Internal validation was done by bootstrap resampling technique. The regression coefficients were transformed into a scoring system. Excessive IBL occurred in 32.7% of patients (118/361). The predictive scoring system included three predictors: </span></span>body mass index<span> (score 0, 1.5, 2: overweight, normal weight, underweight), systolic blood pressure (score 0, 1: &lt;130, ≥130 mmHg), and operative time (score 0, 2.5: ≤4, &gt;4 h). The area under the receiver operating characteristic curve (AUROC) for discrimination ability was 0.828 (internal validation: C-statistic 0.812). Risk was then classified as low (0–2.5 points) or high (3–5.5 points). The prognostic ability of this simplified scoring system was found to be clinically acceptable for predicting excessive IBL during orthognathic surgery.</span></span></div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 53-60"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of dexamethasone-enhanced anaesthetics on postoperative pain, oedema, and trismus following third molar extraction: a systematic review and meta-analysis 地塞米松增强麻醉剂对第三磨牙拔牙术后疼痛、水肿和牙关紧闭的影响:一项系统回顾和荟萃分析
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-08-22 DOI: 10.1016/j.ijom.2025.08.004
I.A. Fernandes , A.C.R. Protásio, I. D'Angelis, M.R.L. Lopes, M.N.L. Baracho, S.G.M. Falci, G.M. de Souza
{"title":"Impact of dexamethasone-enhanced anaesthetics on postoperative pain, oedema, and trismus following third molar extraction: a systematic review and meta-analysis","authors":"I.A. Fernandes ,&nbsp;A.C.R. Protásio,&nbsp;I. D'Angelis,&nbsp;M.R.L. Lopes,&nbsp;M.N.L. Baracho,&nbsp;S.G.M. Falci,&nbsp;G.M. de Souza","doi":"10.1016/j.ijom.2025.08.004","DOIUrl":"10.1016/j.ijom.2025.08.004","url":null,"abstract":"<div><div>The extraction of third molars (3Ms) is frequently associated with postoperative inflammation and discomfort. This systematic review aimed to compare the efficacy of combining local anaesthetics with dexamethasone (treatment group) versus local anaesthetics alone (control group) in 3M surgeries. A comprehensive search of PubMed, Cochrane CENTRAL, Virtual Health Library, and Embase was conducted on June 9, 2025, to identify randomized controlled trials (RCTs) assessing outcomes such as pain, oedema, and trismus. Of 300 studies initially identified, nine met inclusion criteria for qualitative synthesis, and eight were included in the meta-analyses. These studies involved 406 patients and 539 3Ms. The treatment group showed significant improvements in postoperative pain, facial oedema (days 1, 3, and 7), trismus (days 3 and 7), anaesthesia onset time, anaesthesia duration, and pain during anaesthetic injection. Overall, the addition of dexamethasone significantly enhanced clinical outcomes compared to anaesthetics alone. However, the certainty of the evidence remains low due to methodological limitations in the included trials. Further high-quality RCTs, rigorously adhering to standardized protocols, are essential to reduce bias and strengthen the reliability of these findings.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 120-132"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal mandibular fractures: a scoping review 新生儿下颌骨折:范围审查。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-06-24 DOI: 10.1016/j.ijom.2025.06.014
J.H.T. Sng , Y. Zhang , K.Z. Ong
{"title":"Neonatal mandibular fractures: a scoping review","authors":"J.H.T. Sng ,&nbsp;Y. Zhang ,&nbsp;K.Z. Ong","doi":"10.1016/j.ijom.2025.06.014","DOIUrl":"10.1016/j.ijom.2025.06.014","url":null,"abstract":"<div><div><span><span><span>While uncommon, trauma-induced fractures to the neonatal mandible require unique consideration. A scoping review of neonatal </span>mandibular fractures<span> (NMF) was performed, in accordance with the PRISMA-ScR guidelines. The PubMed, Embase, Cochrane Library, Scopus, and Web of Science databases were comprehensively searched, covering the period 1990 to March 2025. All studies that reported NMF (age &lt;28 days) were considered eligible. Due to the nature of the studies found, only a descriptive analysis was performed. Seven articles reporting seven cases of NMF were included. Four cases were birth trauma-induced; two of which were associated with forceps delivery and three were associated with an abnormal foetal position during labour. Various treatment modalities, complications, and durations of follow-up were reported. </span></span>Open reduction was performed in four cases (no fixation, suture fixation, </span>wire fixation<span>, plate and screw fixation performed in one case each) and closed reduction in three (acrylic splint and circummandibular wiring in two, circummandibular wiring alone in one). More studies are needed to explore the association between NMF and birth trauma due to delivery methods and foetal position. Moreover, long term-follow up is required to establish possible implications of NMF and its management on the development of the dentition and facial growth.</span></div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 77-82"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated detection of zygomatic fractures on spiral computed tomography using a deep learning model 利用深度学习模型在螺旋计算机断层扫描上自动检测颧骨骨折。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-08-06 DOI: 10.1016/j.ijom.2025.07.007
A. Yari , P. Fasih , L. Kamali Hakim , A. Asadi
{"title":"Automated detection of zygomatic fractures on spiral computed tomography using a deep learning model","authors":"A. Yari ,&nbsp;P. Fasih ,&nbsp;L. Kamali Hakim ,&nbsp;A. Asadi","doi":"10.1016/j.ijom.2025.07.007","DOIUrl":"10.1016/j.ijom.2025.07.007","url":null,"abstract":"<div><div>The aim of this study was to evaluate the performance of the YOLOv8 deep learning model for detecting zygomatic fractures. Computed tomography scans with zygomatic fractures were collected, with all slices annotated to identify fracture lines across seven categories: zygomaticomaxillary suture, zygomatic arch, zygomaticofrontal suture, sphenozygomatic suture, orbital floor, zygomatic body, and maxillary sinus wall. The images were divided into training, validation, and test datasets in a 6:2:2 ratio. Performance metrics were calculated for each category. A total of 13,988 axial and 14,107 coronal slices were retrieved. The trained algorithm achieved accuracy of 94.2–97.9%. Recall exceeded 90% across all categories, with sphenozygomatic suture fractures having the highest value (96.6%). Average precision was highest for zygomatic arch fractures (0.827) and lowest for zygomatic body fractures (0.692). The highest F1 score was 96.7% for zygomaticomaxillary suture fractures, and the lowest was 82.1% for zygomatic body fractures. Area under the curve (AUC) values were also highest for zygomaticomaxillary suture (0.943) and lowest for zygomatic body fractures (0.876). The YOLOv8 model demonstrated promising results in the automated detection of zygomatic fractures, achieving the highest performance in identifying fractures of the zygomaticomaxillary suture and zygomatic arch.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 68-76"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on “Prevalence and risk factors of suicidal ideation in oral cancer: a systematic review and meta-analysis” 《口腔癌患者自杀意念的患病率及危险因素:一项系统综述和荟萃分析》
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-01-03 DOI: 10.1016/j.ijom.2024.12.007
R. Mehta , A.K. Balaraman , M. Shabil , S. Sah
{"title":"Comment on “Prevalence and risk factors of suicidal ideation in oral cancer: a systematic review and meta-analysis”","authors":"R. Mehta ,&nbsp;A.K. Balaraman ,&nbsp;M. Shabil ,&nbsp;S. Sah","doi":"10.1016/j.ijom.2024.12.007","DOIUrl":"10.1016/j.ijom.2024.12.007","url":null,"abstract":"","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 135-136"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and dental implant outcomes in patients after mandibular continuity reconstruction with bone flaps versus bone grafts: a systematic review and meta-analysis 骨瓣与骨移植物重建下颌连续性患者的临床和牙种植结果:系统回顾和荟萃分析。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-06-20 DOI: 10.1016/j.ijom.2025.06.011
B.C. Mendes , A.M.S. Santos , M.T.V. Rodrigues , J.F. Santiago Junior , E. Hochuli-Vieira , L.P. Faverani
{"title":"Clinical and dental implant outcomes in patients after mandibular continuity reconstruction with bone flaps versus bone grafts: a systematic review and meta-analysis","authors":"B.C. Mendes ,&nbsp;A.M.S. Santos ,&nbsp;M.T.V. Rodrigues ,&nbsp;J.F. Santiago Junior ,&nbsp;E. Hochuli-Vieira ,&nbsp;L.P. Faverani","doi":"10.1016/j.ijom.2025.06.011","DOIUrl":"10.1016/j.ijom.2025.06.011","url":null,"abstract":"<div><div><span>This study was performed to evaluate the failure and complication rates of bone flaps<span><span><span> and bone grafts used for mandible reconstruction following partial </span>mandible resection<span>, and the failure and complication rates of implants installed in these grafts. A systematic review<span> and meta-analysis was conducted following the PRISMA protocol. The level of evidence was assessed according to the National Health and Medical Research Council (Australia) classifications. Quantitative data for failures and complications were pooled and evaluated to determine the overall event rate with 95% confidence interval. Twenty-one studies (seven prospective, 14 retrospective) were identified, including 519 transplants: 423 bone flaps with 1428 implants, and 96 bone grafts with 322 implants. The overall mean event rate for </span></span></span>graft failure<span> was 3.5% for bone flaps and 4.6% for bone grafts, while the rate for complications was 9.9% for bone flaps and 10.5% for bone grafts. The mean event rate for implant failure was 5.5% for bone flaps and 9.9% for bone grafts. The mean event rate for implant complications was 5.9% for bone flaps; however, implant complications were absent in the bone grafts. Failure rates for both flaps and grafts were low, and complication rates were similar (</span></span></span><em>P</em> &gt; 0.05). Implant survival did not differ significantly between the flaps and grafts (<em>P</em> &gt; 0.05). The data must be interpreted with caution, as the studies evaluated had relatively small samples from which to draw comparisons.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 94-109"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative efficacy of patient-specific and stock implants in temporomandibular joint replacement: a systematic review and meta-analysis 患者特异性植入物和固定植入物在颞下颌关节置换术中的比较疗效:一项系统回顾和荟萃分析。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-07-21 DOI: 10.1016/j.ijom.2025.06.021
E.-L. Nolden , B.K.G. Carvalho , A.S. Wenning , S. Kiss-Dala , P. Hegyi , A. Bródy , N.K. Rózsa , D. Végh , L. Köles , M. Vaszilkó
{"title":"Comparative efficacy of patient-specific and stock implants in temporomandibular joint replacement: a systematic review and meta-analysis","authors":"E.-L. Nolden ,&nbsp;B.K.G. Carvalho ,&nbsp;A.S. Wenning ,&nbsp;S. Kiss-Dala ,&nbsp;P. Hegyi ,&nbsp;A. Bródy ,&nbsp;N.K. Rózsa ,&nbsp;D. Végh ,&nbsp;L. Köles ,&nbsp;M. Vaszilkó","doi":"10.1016/j.ijom.2025.06.021","DOIUrl":"10.1016/j.ijom.2025.06.021","url":null,"abstract":"<div><div>Evidence for the superiority of patient-specific implants (PSI) over stock implants in temporomandibular joint (TMJ) replacement remains inconclusive. The objective of this study was to provide guidance for clinical decisions by evaluating whether PSI offer advantages over stock systems in rehabilitation of the TMJ. A systematic search was performed in three databases to identify studies reporting mouth opening, pain, and diet outcomes for PSI and/or stock TMJ implants. Two-arm studies were analysed separately from pooled single- and two-arm studies; studies with comparable follow-up times were compared. Forty-two observational studies involving 2221 patients were included. PSI showed a consistent trend towards greater mouth opening across most follow-up times; however, a significant difference in favour of PSI was only observed in two-arm studies at &gt;12 months (mean difference 5.83 mm; <em>P</em> = 0.025). Pain outcomes were mixed: stock implants favored early pain and late diet change, while PSI favored pain relief at 6–24 months. The findings suggest PSI should be considered for movement restrictions, while stock implants may provide an alternative for pain and dietary needs. Due to the observational nature of the included studies and differences in study populations across arms, the findings should be interpreted with caution.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 83-93"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of frozen section pathology in oral squamous cell carcinoma: a systematic review and meta-analysis 冷冻切片病理在口腔鳞状细胞癌中的应用:一项系统综述和荟萃分析。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-09-24 DOI: 10.1016/j.ijom.2025.08.006
L.T.D. Armstrong, N.M. Beech, O. Breik, M.D. Batstone
{"title":"Utility of frozen section pathology in oral squamous cell carcinoma: a systematic review and meta-analysis","authors":"L.T.D. Armstrong,&nbsp;N.M. Beech,&nbsp;O. Breik,&nbsp;M.D. Batstone","doi":"10.1016/j.ijom.2025.08.006","DOIUrl":"10.1016/j.ijom.2025.08.006","url":null,"abstract":"<div><div>The impact of intraoperative frozen section analysis on final margin status, loco-regional recurrence, and survival in patients with oral squamous cell carcinoma (OSCC) remains uncertain. This systematic review and meta-analysis was performed to compare outcomes of OSCC resections performed with intraoperative frozen section analysis versus gross clinical examination alone. Primary outcomes included final margin status, recurrence, and survival. The literature search was performed on August 18, 2024 via PubMed, Embase, Scopus, and Cochrane Library. R statistical software was used for the data synthesis, and the quality of evidence was evaluated with the GRADE framework. Five studies met the inclusion criteria. Meta-analysis showed no significant difference in the pooled estimates for clear margins (relative risk (RR) 1.01, 95% confidence interval (CI) 0.97–1.06), positive margins (RR 0.84, 95% CI 0.26–2.73), or close margins (RR 0.86, 95% CI 0.61–1.20) between the frozen section and clinical examination cohorts. A narrative synthesis for recurrence and survival outcomes also demonstrated no significant differences. GRADE assessment indicated a low level of evidence quality and certainty of results. Current evidence does not support a clear advantage of intraoperative frozen section analysis over gross examination alone for improving margin status, recurrence, or survival in OSCC. Further prospective, high-quality, and possibly randomized studies are needed to establish the definitive role of frozen section in improving patient outcomes.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 1-9"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Board/Reviewing Committee 编辑委员会/评审委员会
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1016/S0901-5027(25)01519-X
{"title":"Editorial Board/Reviewing Committee","authors":"","doi":"10.1016/S0901-5027(25)01519-X","DOIUrl":"10.1016/S0901-5027(25)01519-X","url":null,"abstract":"","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Page i"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145808535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does chemotherapy improve the prognosis in patients with jaw osteosarcoma? A systematic review and meta-analysis 化疗能改善颌骨骨肉瘤患者的预后吗?系统回顾和荟萃分析。
IF 2.7 3区 医学
International journal of oral and maxillofacial surgery Pub Date : 2026-01-01 Epub Date: 2025-09-29 DOI: 10.1016/j.ijom.2025.09.008
L. Zhang , Y. Guo , Y. Sumita , H. Hirai , M. Yamazaki , T. Hayashi , J.-i. Tanuma , K. Tomihara
{"title":"Does chemotherapy improve the prognosis in patients with jaw osteosarcoma? A systematic review and meta-analysis","authors":"L. Zhang ,&nbsp;Y. Guo ,&nbsp;Y. Sumita ,&nbsp;H. Hirai ,&nbsp;M. Yamazaki ,&nbsp;T. Hayashi ,&nbsp;J.-i. Tanuma ,&nbsp;K. Tomihara","doi":"10.1016/j.ijom.2025.09.008","DOIUrl":"10.1016/j.ijom.2025.09.008","url":null,"abstract":"<div><div>Osteosarcoma, a rare tumour, primarily affects the long bones in young individuals. However, it can also involve the jaw, presenting as jaw osteosarcoma (JOS), which is characterized by higher local recurrence than metastasis. While advances in chemotherapy have contributed to the treatment of osteosarcoma, its role in JOS remains debated. This study was performed to evaluate the effects of chemotherapy on survival outcomes. A systematic search for studies published between 1990 and 2024 was conducted using PubMed, Embase, and Google Scholar. Eligible studies reported survival data for histologically confirmed JOS cases. Kaplan–Meier analysis and Cox regression were performed to assess survival rates and prognostic factors. The analysis included 330 patients from 20 studies. The 5-year overall survival rate was 37.1% and the 10-year rate was 10.5%. Age (≥40 years), surgical margin status (positive), and tumour size (≥5 cm) were identified as significant prognostic factors (worse prognosis). Importantly, patients with high-grade JOS treated with both surgery and chemotherapy (versus surgery without chemotherapy) demonstrated improved survival (hazard ratio 0.500, 95% confidence interval 0.262–0.954, <em>P =</em> 0.035). Overall, chemotherapy provided significant benefit in high-grade cases. This study provides valuable insights for refining treatment protocols for this rare tumour type.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 1","pages":"Pages 10-19"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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