{"title":"The prognostic value of pre-treatment sarcopenia in overall survival in head and neck cancer patients: a systematic review","authors":"A. Syziu, A. Schache","doi":"10.1016/j.ijom.2024.07.008","DOIUrl":"10.1016/j.ijom.2024.07.008","url":null,"abstract":"<div><div>The aim of this study was to determine the prognostic value of pre-treatment sarcopenia, defined radiologically (cervical (C3) or lumbar (L3) region), in adult head and neck cancer (HNC) patients undergoing treatment with curative intent. A systematic search of the PubMed and Scopus databases was performed up to March 2024. Inclusion criteria were adult patients with locally advanced HNC, sarcopenia defined radiologically at the C3 and/or L3 level, and patients receiving primary treatment with curative intent. Risk of bias was assessed using the ROBINS-I tool non-randomised studies. Thirty studies involving a total of 6924 adult patients with HNC were included in this review. Pre-treatment sarcopenia was significantly associated with worse overall survival outcomes in 26 of the 30 studies (87%), across all treatment modalities with curative intent. The most frequent sex-specific SMI cut-off values were <52.4 cm<sup>2</sup>/m<sup>2</sup> for males and <38.5 cm<sup>2</sup>/m<sup>2</sup> for females. The findings of this review suggest that sarcopenia is a strong prognostic factor of overall survival in HNC patients undergoing primary curative treatment. Sarcopenia evaluation appears to be a good prognostic marker in the HNC population. Future nutritional interventional studies might focus on reversing the muscle loss and improving overall outcomes in identified sarcopenic individuals.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 1","pages":"Pages 1-11"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W.K. Zhou , J.J. Wang , Y.H. Jiang , L. Yang , Y.L. Luo , Y. Man , J. Wang
{"title":"Clinical and in vitro application of robotic computer-assisted implant surgery: a scoping review","authors":"W.K. Zhou , J.J. Wang , Y.H. Jiang , L. Yang , Y.L. Luo , Y. Man , J. Wang","doi":"10.1016/j.ijom.2024.09.006","DOIUrl":"10.1016/j.ijom.2024.09.006","url":null,"abstract":"<div><div>In recent years, the emergence and application of robotic computer-assisted implant surgery (r-CAIS) has resulted in a revolutionary shift in conventional implant diagnosis and treatment. This scoping review was performed to verify the null hypothesis that r-CAIS has a relatively high accuracy of within 1 mm, with relatively few complications and a short operative time. This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR). From the 3355 publications identified in the PubMed, Scopus, Web of Science, and Google Scholar databases, 28 were finally included after a comprehensive review and analysis. The null hypothesis is partly accepted, as r-CAIS has a relatively high accuracy (coronal and apical deviation within 1 mm), and no significant adverse events or complications have been reported to date, although additional confirmatory studies are needed. However, there is insufficient evidence for a shorter surgical time, and further clinical research on this topic is required.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 1","pages":"Pages 74-81"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in lateral standing posture following orthognathic surgery: a cohort study","authors":"F. Akhlaghi, Z.S. Torabi, R. Tabrizi","doi":"10.1016/j.ijom.2024.06.011","DOIUrl":"10.1016/j.ijom.2024.06.011","url":null,"abstract":"<div><div>Altering neuromuscular and musculoskeletal relationships also affects standing body posture, particularly in the head and neck areas. This prospective cohort study<span><span> assessed the effects of orthognathic surgery on head posture in the lateral standing view. Thirty-one patients who underwent single-jaw orthognathic mandibular surgery were included. The patients underwent </span>cephalometric<span> and photographic evaluations of their habitual posture before and 6 months after surgery. The craniovertebral angle and Frankfort angle were determined and measured using MB-Ruler software. Mandibular positional changes were also measured by superimposing lateral cephalograms<span><span> and recording changes in the menton point. All data were analysed by paired t-test. The craniovertebral angle increased significantly in patients with Class II malocclusion (P = 0.001) and decreased significantly in Class III patients (P = 0.004). Furthermore, the Frankfort angle was significantly increased in both Class II (P = 0.005) and Class III (P = 0.012) patients. The tendency towards </span>forward head posture decreased in Class II patients, and the neck posture improved. Conversely, a slight but significant tendency towards a forward head posture was observed in Class III patients after surgery. Furthermore, the natural head position changed in both study groups, leading to a more upright head posture</span></span></span></div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 1","pages":"Pages 51-56"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Ye , G. Tan , L. Wang , G. Shangguan , H. Yao , X. Xu , H. Ye , X. Ding
{"title":"Comparison of survival between palliative surgery and no surgery for advanced tongue squamous cell carcinoma: an analysis of SEER data","authors":"Z. Ye , G. Tan , L. Wang , G. Shangguan , H. Yao , X. Xu , H. Ye , X. Ding","doi":"10.1016/j.ijom.2024.07.001","DOIUrl":"10.1016/j.ijom.2024.07.001","url":null,"abstract":"<div><div><span><span><span><span>The aim of this study was to investigate the survival effect of palliative surgery in advanced </span>tongue squamous cell carcinoma (TSCC). A retrospective analysis of data in the </span>SEER<span> database for 6151 patients with stage III/IV TSCC (American Joint Committee on Cancer (AJCC) staging), diagnosed between 2004 and 2015, was performed. The patients were divided into two groups: palliative surgery and no surgery. Kaplan–Meier and Cox proportional hazards regression analyses were applied to determine risk factors for overall survival (OS) and cancer-specific survival (CSS). A further analysis was performed using 1:1 </span></span>propensity score matching<span> (PSM) to balance 13 patient variables (sex, age at diagnosis, race, marital status, primary tumour site, SEER stage, AJCC stage, pathological differentiation grade, tumour size, lymph node metastasis, previous lymph node removal, radiotherapy, and chemotherapy). Among the 6151 patients, 706 underwent palliative surgery; the other 5445 did not undergo any kind of surgery. Those who underwent palliative surgery had a higher 5-year survival rate. After PSM, 1274 patients were included in the matched cohort. Multivariate Cox regression analysis showed that patients who underwent palliative surgery had a lower risk of death than those who did not (OS: hazard ratio 0.58, 95% confidence interval 0.49–0.69, </span></span><em>P</em> < 0.001; CSS: hazard ratio 0.60, 95% confidence interval 0.49–0.74, <em>P</em> < 0.001). In this comparative study it was found that compared with no surgery, palliative surgery has a positive impact on the survival rate of patients with advanced TSCC.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 1","pages":"Pages 12-22"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “The impact and opportunities of large language models like ChatGPT in oral and maxillofacial surgery: a narrative review”","authors":"H. Daungsupawong , V. Wiwanitkit","doi":"10.1016/j.ijom.2023.11.014","DOIUrl":"10.1016/j.ijom.2023.11.014","url":null,"abstract":"","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 1","pages":"Page 93"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139668011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Premalignant lesions of the oral cavity: a narrative review of factors and mechanisms of transformation into cancer","authors":"E.A. Prostakishina , E.A. Sidenko , E.S. Kolegova , M.R. Patysheva , G.A. Kononova , E.L. Choinzonov","doi":"10.1016/j.ijom.2024.12.006","DOIUrl":"10.1016/j.ijom.2024.12.006","url":null,"abstract":"<div><div>Oral squamous cell carcinoma (OSCC) is the most common type of head and neck cancer. The development and progression of OSCC are closely linked to various aetiological factors. Early signs of OSCC may manifest as oral lesions, genetic abnormalities, and chronic inflammation. Lesions with dysplastic features have a high risk of malignant transformation into OSCC. Moreover, dysplastic lesions are characteristic of many oral potentially malignant disorders (OPMDs). Currently, there is no unified standard of treatment for OPMD patients, due to the variability in risk factors and mechanisms of transformation. Therefore, it is essential to detect and manage OPMDs at an early stage in order to prevent their malignant transformation into OSCC. This necessitates analysing OPMD mechanisms to identify objective markers for predicting the risk of malignant transformation. The aim of this review was to describe the process of OPMD transformation into OSCC under the influence of environmental, immune, microbiome, and molecular factors.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 6","pages":"Pages 479-493"},"PeriodicalIF":2.2,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Kurita , N. Uzawa , H. Nakayama , T. Abe , S. Ibaraki , Y. Ohyama , K. Uchida , H. Sato , S. Miyabe , T. Abé , N. Kakimoto , A. Kaida , T. Sugiura , M. Kioi , A. Danjo , N. Kitamura , O. Hasegawa , T. Tanaka , N. Ueda , T. Hasegawa , T. Kirita
{"title":"Japanese clinical practice guidelines for oral cancer, 2023","authors":"H. Kurita , N. Uzawa , H. Nakayama , T. Abe , S. Ibaraki , Y. Ohyama , K. Uchida , H. Sato , S. Miyabe , T. Abé , N. Kakimoto , A. Kaida , T. Sugiura , M. Kioi , A. Danjo , N. Kitamura , O. Hasegawa , T. Tanaka , N. Ueda , T. Hasegawa , T. Kirita","doi":"10.1016/j.ijom.2024.11.012","DOIUrl":"10.1016/j.ijom.2024.11.012","url":null,"abstract":"<div><div>The Japanese Society of Oral Oncology and Japanese Society of Oral and Maxillofacial Surgeons have jointly developed clinical practice guidelines for oral cancer (oral squamous cell carcinoma) to improve and standardize the quality of oral cancer treatment in Japan. The first, second, and third editions were published in 2009, 2013, and 2019, respectively, and the 2023 edition was recently developed. In the development of the 2023 edition, 60 clinical questions (CQs) were listed. Systematic reviews following the GRADE approach were performed for 11 of these CQs. This article outlines the 2023 edition and describes the most relevant guidelines and CQs for the diagnosis, treatment, follow-up, and supportive care of oral cancer patients in Japan.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 5","pages":"Pages 461-476"},"PeriodicalIF":2.2,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Zeng , H. Lin , W. Deng , R. Zhou , T. Wu , B. Liu
{"title":"Learning curve in mandibular reconstruction with vascularized iliac crest free flap: a cumulative sum analysis","authors":"B. Zeng , H. Lin , W. Deng , R. Zhou , T. Wu , B. Liu","doi":"10.1016/j.ijom.2024.12.003","DOIUrl":"10.1016/j.ijom.2024.12.003","url":null,"abstract":"<div><div>The repair of mandibular defects is challenging due to the functional and structural complexity of the mandible. The aim of this study was to evaluate the learning curve of mandibular reconstruction using a vascularized iliac crest free flap (ICFF) performed by a single surgeon. This retrospective study used the cumulative sum (CUSUM) method to analyse the operation times of 60 patients who underwent mandibular reconstruction surgery with an ICFF between 2013 and 2022. The results showed that the learning curve could be divided into two phases according to the turning point: phase 1 comprised cases 1–17 and phase 2 comprised cases 18–60. The operation time and length of hospital stay were significantly longer in phase 1 than in phase 2, while there was no significant difference in the flap failure rate or follow-up outcomes between the two phases. In summary, the learning curve of mandibular reconstruction with an ICFF stabilized after approximately 17 cases.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 4","pages":"Pages 322-328"},"PeriodicalIF":2.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Composite graft for the prevention and correction of a deep labiomental fold after advancement genioplasty","authors":"F. Carlino","doi":"10.1016/j.ijom.2024.11.006","DOIUrl":"10.1016/j.ijom.2024.11.006","url":null,"abstract":"<div><div>When an advancement genioplasty exceeds 3-4 mm an unpleasant fold may arise between lower lip and chin, especially in patients with thin skin. To flatten the labiomental fold, a solid graft can be inserted into the concavity between alveolar process and chin prominence. An original technique is proposed that uses a composite graft made of a bone block fixed directly to the mandibular basal bone and covered with a layer of cartilage, to overcome the flaws associated with previously described techniques. This technique was used over a 7-year period to treat 38 patients, either to prevent or to correct an excessively deep labiomental fold after advancement genioplasty, or simply to fill an existing deep fold even though a genioplasty was not performed. Only two cases of failure occurred: one due to suture dehiscence, the other due to infection of the graft. The graft also provides support to the lower lip and corrects the sagittal discrepancy between the basal bone (i.e. chin) and alveolar bone (i.e. teeth and lower lip) that often coexists in these patients. The procedure takes only a few minutes and presents a minimal risk of complications; therefore, it can be considered a simple and effective technique.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 6","pages":"Pages 543-548"},"PeriodicalIF":2.2,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Morikawa , M. Shingyouchi , T. Ariizumi , A. Watanabe , T. Shibahara , A. Katakura
{"title":"Performance of image processing analysis and a deep convolutional neural network for the classification of oral cancer in fluorescence visualization","authors":"T. Morikawa , M. Shingyouchi , T. Ariizumi , A. Watanabe , T. Shibahara , A. Katakura","doi":"10.1016/j.ijom.2024.11.010","DOIUrl":"10.1016/j.ijom.2024.11.010","url":null,"abstract":"<div><div>The aim of this prospective study was to determine the effectiveness of screening using image processing analysis and a deep convolutional neural network (DCNN) to classify oral cancers using non-invasive fluorescence visualization. The study included 1076 patients with diseases of the oral mucosa (oral cancer, oral potentially malignant disorders (OPMDs), benign disease) or normal mucosa. For oral cancer, the rate of fluorescence visualization loss (FVL) was 96.9%. Regarding image processing, multivariate analysis identified FVL, the coefficient of variation of the G value (CV), and the G value ratio (VRatio) as factors significantly associated with oral cancer detection. The sensitivity and specificity for detecting oral cancer were 96.9% and 77.3% for FVL, 80.8% and 86.4% for CV, and 84.9% and 87.8% for VRatio, respectively. Regarding the performance of the DCNN for image classification, recall was 0.980 for oral cancer, 0.760 for OPMDs, 0.960 for benign disease, and 0.739 for normal mucosa. Precision was 0.803, 0.821, 0.842, and 0.941, respectively. The F-score was 0.883, 0.789, 0.897, and 0.828, respectively. Sensitivity and specificity for detecting oral cancer were 98.0% and 92.7%, respectively. The accuracy for all lesions was 0.851, average recall was 0.860, average precision was 0.852, and average F-score was 0.849.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"54 6","pages":"Pages 511-518"},"PeriodicalIF":2.2,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}