International journal of oral and maxillofacial surgery最新文献_第2页

Enamel matrix derivative in the prevention and treatment of medication-related osteonecrosis of the jaws in rats 牙釉质基质衍生物在预防和治疗大鼠药物相关性颌骨坏死中的作用。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-03-01 Epub Date: 2025-09-19 DOI: 10.1016/j.ijom.2025.09.004

C. Eren , C.Y. Asan , A. Kara , C. Topan , A.E. Demirbas

{"title":"Enamel matrix derivative in the prevention and treatment of medication-related osteonecrosis of the jaws in rats","authors":"C. Eren , C.Y. Asan , A. Kara , C. Topan , A.E. Demirbas","doi":"10.1016/j.ijom.2025.09.004","DOIUrl":"10.1016/j.ijom.2025.09.004","url":null,"abstract":"<div><div>The aim of this study was to evaluate the effectiveness of enamel matrix derivative (EMD) in preventing and treating medication-related osteonecrosis of the jaws (MRONJ). The study included 60 rats divided into five equal-sized groups. The preventive effect of EMD was evaluated in groups 1 (healthy control), 2 (bisphosphonate control), and 3 (bisphosphonate + EMD), and treatment efficacy was examined in groups 4 (osteonecrosis control) and 5 (osteonecrosis + EMD). Intraperitoneal zoledronic acid was administered to induce MRONJ, and the left mandibular molar teeth were extracted in all groups. Saline-impregnated absorbable collagen sponges (ACS) were placed in the extraction sockets of the control groups, and EMD-impregnated ACS were placed in the study groups. After 8 weeks of healing, histomorphometry, immunohistochemistry, and micro-CT analyses were performed. The rate of complete mucosal closure in the extraction socket was significantly higher in the EMD groups compared to the controls (<em>P</em> = 0.015 , <em>P</em> = 0.009). VEGF, OPG, and RANKL expression levels were higher in the EMD groups compared to their respective controls; however, this was only significant for group 3 vs group 2 (all <em>P</em> < 0.01). Micro-CT examinations demonstrated significantly improved values in the EMD groups compared to the controls. EMD administration may enhance soft and hard tissue healing in MRONJ cases, promoting angiogenesis and bone apposition and increasing levels of VEGF and OPG. EMD may be a potential agent for the prevention and treatment of osteonecrosis.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 3","pages":"Pages 310-318"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative delirium is associated with increased long-term mortality following oral and maxillofacial reconstructive surgery 术后谵妄与口腔颌面重建手术后长期死亡率增加有关。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-03-01 Epub Date: 2025-09-29 DOI: 10.1016/j.ijom.2025.09.007

Y. Nitta , T. Sanuki , S. Sugino , M. Sugimoto , K. Kido

{"title":"Postoperative delirium is associated with increased long-term mortality following oral and maxillofacial reconstructive surgery","authors":"Y. Nitta , T. Sanuki , S. Sugino , M. Sugimoto , K. Kido","doi":"10.1016/j.ijom.2025.09.007","DOIUrl":"10.1016/j.ijom.2025.09.007","url":null,"abstract":"<div><div>The aim of this study was to determine the impact of postoperative delirium (POD) on 2-year survival and identify perioperative risk factors contributing to POD in patients undergoing oral and maxillofacial reconstructive surgery. A retrospective observational study was conducted at Hokkaido University Hospital. The cohort included 65 patients who underwent oral and maxillofacial reconstructive surgery between January 2016 and May 2022. Patients were categorized into POD (<em>n</em> = 20) and non-POD (<em>n</em> = 45) groups. POD diagnosis was based on clinical criteria assessed by psychiatrists. Survival was analysed using Kaplan–Meier curves and a Cox proportional hazards model adjusted for age, American Society of Anesthesiologists (ASA) physical status, malignancy, and disease classification. POD occurred in 30.8% of patients. Two-year survival estimated by Kaplan–Meier analysis was significantly lower in POD group (60%) than in non-POD group (87%) (<em>P</em> = 0.009). POD was an independent risk factor for decreased survival (hazard ratio 3.40, 95% confidence interval 1.10–10.57; <em>P</em> = 0.034). No significant perioperative predictors of POD were identified. POD was associated with a substantial decrease in long-term survival following oral and maxillofacial reconstructive surgery. Early recognition and management of POD are critical to improving outcomes in this high-risk population.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 3","pages":"Pages 284-291"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-dimensional assessment of the malar bone implant engagement of 100 zygomatic implants: a retrospective study 100个颧骨植入体颧骨植入体接合的三维评估：回顾性研究。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-03-01 Epub Date: 2025-09-06 DOI: 10.1016/j.ijom.2025.08.009

F. Zingari , F. Gallo , A. Madonna , S. Barone , M. Borelli , A. Giudice

{"title":"Three-dimensional assessment of the malar bone implant engagement of 100 zygomatic implants: a retrospective study","authors":"F. Zingari , F. Gallo , A. Madonna , S. Barone , M. Borelli , A. Giudice","doi":"10.1016/j.ijom.2025.08.009","DOIUrl":"10.1016/j.ijom.2025.08.009","url":null,"abstract":"<div><div>This study was performed to evaluate the amount of bone implant engagement (BIE) of zygomatic implants (ZIs) at the malar bone level and its correlation with the ZAGA classification (zygoma anatomy-guided approach). One hundred ZIs placed in 32 patients with severe maxillary atrophy using a fully digital protocol were assessed: 80 placed in pairs (40 anterior (AI), 40 posterior (PI)) and 20 as single ZIs (SI). The ZAGA classification was determined preoperatively. Postoperative computed tomography scans were analysed using 3D Slicer to measure medial and lateral BIE, the mean value of these (mvBIE), and the ferrule area. Comparisons of the mean mvBIE of the implants (AI, PI, SI) were made according to the ZAGA categories and within each ZAGA group. Descriptive statistics and a linear mixed-effects model were performed (α = 0.05). The overall mean mvBIE was 12.38 ± 3.53 mm (AI: 12.38 ± 3.85 mm, PI: 11.50 ± 3.01 mm, SI: 14.16 ± 3.32 mm). A significant relationship was found between mvBIE and the ZAGA classification (0.005 < <em>P</em> < 0.008), with the lowest mean mvBIE in ZAGA 0 and ZAGA 4, and progressively increasing from ZAGA 1 to ZAGA 3. The mean mvBIE was significantly lower in PI compared to AI and SI (0.001 < <em>P</em> < 0.011). Three-dimensional analysis provided detailed measurements of mvBIE in ZIs placed using a digitally guided protocol. Considerable mvBIE variation among implant positions between and within ZAGA categories was observed, highlighting the influence of implant location and anatomy on bone engagement.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 3","pages":"Pages 358-367"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Volumetric variations in the buccal fat pad, parapharyngeal adipose corpus, and orbital fat according to sex, age, and body mass index: an MRI study with segmentation 颊脂肪垫、咽旁脂肪体和眶脂肪根据性别、年龄和体重指数的体积变化：一项分割的MRI研究。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-03-01 Epub Date: 2025-08-30 DOI: 10.1016/j.ijom.2025.08.001

A. Fernandez , L.-D. Rivière , T. Canceill , A. Dubuc , G. Fournier , F. Savall , G. de Bonnecaze

{"title":"Volumetric variations in the buccal fat pad, parapharyngeal adipose corpus, and orbital fat according to sex, age, and body mass index: an MRI study with segmentation","authors":"A. Fernandez , L.-D. Rivière , T. Canceill , A. Dubuc , G. Fournier , F. Savall , G. de Bonnecaze","doi":"10.1016/j.ijom.2025.08.001","DOIUrl":"10.1016/j.ijom.2025.08.001","url":null,"abstract":"<div><div>The buccal fat pad (BFP), pharyngeal adipose corpus (PAC), and orbital fat are deep fatty compartments of the face that are often considered as non-mobilized fat and are excluded from lipid metabolism. There is considerable clinical inter-individual variability in BFP volume. The PAC volume, which is influenced by weight gain, may be involved in obstructive sleep apnoea syndrome. The aim of this study was to (1) establish well-defined segmentation protocols for the deep fat compartments of the midface; (2) study the volumetric variation in the deep fat compartments of the face according to body mass index (BMI), age, and sex; and (3) compare the behaviours of these fat volumes with each other. Volumes were measured using 3D segmentation tools (3D Slicer). This multicentre study investigated 63 MRI obtained retrospectively. Sex, age, and BMI data were collected from the patient files. The facial deep fat volumes were found to be positively correlated with age and BMI, to varying degrees but in the same direction. No difference in volumes was found between males and females: BFP, <em>P</em> = 0.70; PAC, <em>P</em> = 0.19; orbital fat, <em>P</em> = 0.11. A patient’s age and BMI may provide clues as to the volumes of the deep fat compartments. These findings provide a strong foundation for further studies.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 3","pages":"Pages 302-309"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bony mucoperiosteal flap in bony impacted upper third molar surgery 骨粘骨膜瓣在骨阻生上第三磨牙手术中的应用。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-03-01 Epub Date: 2025-07-19 DOI: 10.1016/j.ijom.2025.07.004

J. Qian , J. Liang , J. Li , W. Zhou , L. Hu , W. Qi

{"title":"Bony mucoperiosteal flap in bony impacted upper third molar surgery","authors":"J. Qian , J. Liang , J. Li , W. Zhou , L. Hu , W. Qi","doi":"10.1016/j.ijom.2025.07.004","DOIUrl":"10.1016/j.ijom.2025.07.004","url":null,"abstract":"<div><div>This prospective study introduces a novel maxillary tuberosity bony mucoperiosteal flap technique with repositioning and preservation of the bony tuberosity, for the extraction of bony impacted upper third molars (BIUTMs). Twenty-eight BIUTMs in 24 patients were randomly assigned to two groups according to the strategy for extraction. In the experimental group (Exp, 16 BIUTMs), bone preservation was achieved through a bone-splitting method using piezoelectric surgery (bony mucoperiosteal flap), elevating the overlying bone and connected mucoperiosteum as a single unit. In the control group (Con, 12 BIUTMs), the BIUTMs were extracted after flap elevation and bone removal. The surgical duration, postoperative complications (swelling, trismus, and pain (visual analogue scale (VAS) score and total ibuprofen consumption over 7 days)), infection, and sinus perforation were evaluated. Patients in Exp showed a greater total ibuprofen consumption than the Con patients (<em>P</em> = 0.009). Despite marginally longer surgical durations in the Exp (<em>P</em> = 0.075), there was no difference in postoperative pain (VAS), swelling, or trismus between the groups. Intraoperative sinus perforation and postoperative infection were not observed in either group. In conclusion, this study introduces a novel surgical approach for extracting BIUTMs. Long-term follow-up is necessary to evaluate the sustained impact on bone preservation.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 3","pages":"Pages 385-391"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structured clinical evaluation for rapid identification of temporomandibular joint closed lock 快速识别颞下颌关节闭锁的结构化临床评价。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-03-01 Epub Date: 2025-08-14 DOI: 10.1016/j.ijom.2025.07.009

W. Abboud , S. Reiter , O. Peleg , P. Friedman-Rubin , T. SellaTunis , D. Shamir , M. Joachim

{"title":"Structured clinical evaluation for rapid identification of temporomandibular joint closed lock","authors":"W. Abboud , S. Reiter , O. Peleg , P. Friedman-Rubin , T. SellaTunis , D. Shamir , M. Joachim","doi":"10.1016/j.ijom.2025.07.009","DOIUrl":"10.1016/j.ijom.2025.07.009","url":null,"abstract":"<div><div>Temporomandibular joint (TMJ) closed lock, corresponding to Wilkes stage 3 internal derangement, is a common cause of restricted mouth opening and functional impairment. Early diagnosis is essential but challenging, particularly when imaging is unavailable. This study analyzed 40 consecutive patients diagnosed with TMJ closed lock. Patients were routinely evaluated using a standardized 11-test assessment format as part of regular practice, and these records were retrospectively analyzed. Statistical analysis compared findings between the affected and non-affected joints and the muscles of mastication. The most frequent clinical findings included tenderness in the affected joint on passive stretch (75%), on palpation (67.5%), on contralateral movement (57.5%), and on contralateral loading (47.5%). On average, the affected joint was tender in 4.1 of 11 tests, while the contralateral joint was positive in only 0.2 tests (P < 0.001). Passive stretch increased mouth opening from 27.1 mm to 31.7 mm, with a hard end feel observed in 85% of patients. Muscular tenderness was observed in 32.5% of patients, most commonly in the ipsilateral masseter (25%) and temporalis (12.5%). These findings support structured clinical evaluation for early recognition of TMJ closed lock, improving diagnostic accuracy and enabling timely intervention.</div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 3","pages":"Pages 351-357"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Reply 对“锥束计算机断层扫描与全景成像检测关节隆起气肿的比较”评论的回应。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-02-01 Epub Date: 2025-09-05 DOI: 10.1016/j.ijom.2025.08.008

E. Katı , G. Akçiçek , H.Y. Zengin

引用次数: 0

Evaluation of post-surgical outcomes in mandibular asymmetry with three-dimensional cephalometric analysis 三维头颅测量分析评价下颌不对称术后疗效。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-02-01 Epub Date: 2025-06-24 DOI: 10.1016/j.ijom.2025.06.016

L.H. Chan, Y.Y. Leung

{"title":"Evaluation of post-surgical outcomes in mandibular asymmetry with three-dimensional cephalometric analysis","authors":"L.H. Chan, Y.Y. Leung","doi":"10.1016/j.ijom.2025.06.016","DOIUrl":"10.1016/j.ijom.2025.06.016","url":null,"abstract":"<div><div><span><span><span><span>Facial asymmetry is common among orthognathic patients, particularly in Southern Chinese populations. Mandibular asymmetry is a prominent manifestation of facial asymmetry and is frequently observed in skeletal Class III patients. Various three-dimensional (3D) imaging techniques, such as </span>cone beam computed tomography<span> (CBCT), are utilized to evaluate skeletal asymmetry. Orthognathic surgery is the definitive treatment for the correction of facial asymmetry; however, the positions of vital structures may constrain surgical access to certain anatomical regions, resulting in residual asymmetry. A 3D analysis – RBC </span></span>cephalometric analysis – categorizes mandibular asymmetry based on a severity grading across three distinct anatomical regions: ramus (R), body (B), and chin (C). This analysis was applied to the data of 57 patients, and their preoperative and postoperative </span>CBCT scans<span> were compared. The findings indicated significant corrections in height at ramus and chin, while asymmetry in height and width at the mandible body could not be adequately corrected. No significant difference in the degree of mandibular asymmetry correction achieved was observed between intraoral vertical ramus </span></span>osteotomy<span> and sagittal split ramus osteotomy. Through the application of the RBC cephalometric analysis, this study identified and evaluated the limitations of orthognathic surgery in the context of asymmetry correction.</span></div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 2","pages":"Pages 202-211"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine learning approach using radiomics features to distinguish odontogenic cysts and tumours 使用放射组学特征的机器学习方法来区分牙源性囊肿和肿瘤。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-02-01 Epub Date: 2025-07-04 DOI: 10.1016/j.ijom.2025.06.020

H. Muraoka, T. Kaneda, K. Ito, K. Otsuka, S. Tokunaga

{"title":"Machine learning approach using radiomics features to distinguish odontogenic cysts and tumours","authors":"H. Muraoka, T. Kaneda, K. Ito, K. Otsuka, S. Tokunaga","doi":"10.1016/j.ijom.2025.06.020","DOIUrl":"10.1016/j.ijom.2025.06.020","url":null,"abstract":"<div><div>Although most odontogenic lesions in the jaw are benign, treatment varies widely depending on the nature of the lesion. This study was performed to assess the ability of a machine learning (ML) model using computed tomography<span><span> (CT) and magnetic resonance imaging (MRI) radiomic features to classify </span>odontogenic cysts<span><span> and tumours. CT and MRI data from patients with odontogenic lesions including dentigerous cysts, </span>odontogenic keratocysts<span>, and ameloblastomas were analysed. Manual segmentation of the CT image and the apparent diffusion coefficient (ADC) map from diffusion-weighted MRI was performed to extract radiomic features. The extracted radiomic features were split into training (70%) and test (30%) sets. The random forest model was adjusted or optimized using 5-fold stratified cross-validation within the training set and assessed on a separate hold-out test set. Analysis of the CT-based ML model showed cross-validation accuracy of 0.59 and 0.60 for the training set and test set, respectively, with precision, recall, and F1 score all being 0.57. Analysis of the ADC-based ML model showed cross-validation accuracy of 0.90 and 0.94 for the training set and test set, respectively; the precision, recall, and F1 score were all 0.87. ML models, particularly when using MRI radiological features, can effectively classify odontogenic lesions.</span></span></span></div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 2","pages":"Pages 182-187"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical features and management of odontogenic keratocysts in Gorlin–Goltz syndrome Gorlin-Goltz综合征牙源性角化囊肿的临床特点及治疗。

IF 2.7 3区医学

International journal of oral and maxillofacial surgery Pub Date : 2026-02-01 Epub Date: 2025-06-19 DOI: 10.1016/j.ijom.2025.06.009

J.T.W. Li , C.C.J. Wan , A.W.K. Yeung , Y.Y. Leung , Y.-X. Su

{"title":"Clinical features and management of odontogenic keratocysts in Gorlin–Goltz syndrome","authors":"J.T.W. Li , C.C.J. Wan , A.W.K. Yeung , Y.Y. Leung , Y.-X. Su","doi":"10.1016/j.ijom.2025.06.009","DOIUrl":"10.1016/j.ijom.2025.06.009","url":null,"abstract":"<div><div><span>One of the frequent manifestations of Gorlin–Goltz syndrome (GGS), a rare autosomal dominant disorder, is the development of </span>odontogenic keratocysts<span><span> (OKCs). The aim of this study was to evaluate the efficacy and safety of treatment modalities for OKCs in GGS patients, and their corresponding recurrence/new lesion rates and complications. Twelve GGS patients (eight male, four female) with 36 OKCs were included. Common clinical features of GGS were calcification of the falx cerebri (eight patients, 66.7%), macrocephaly<span> (seven patients, 58.3%), and frontal bossing<span> (six patients, 50%). Enucleation<span> with Carnoy’s solution was the primary treatment for 10 patients, while two underwent marsupialization. The mean follow-up was 13.3 years. Nine (75%) of the patients did not experience any early complications (up to 1 month postoperative). The OKC recurrence/new lesion rate was 83.3% after surgical treatment (enucleation or marsupialization), with five patients (41.7%) experiencing two occurrences of OKCs during follow-up (range 2.7–29.9 years). Enucleation of OKCs with Carnoy’s solution is a safe and effective approach in GGS patients. However, the high recurrence/new lesion rate underscores the need for close long-term monitoring for at least 7 years and consideration of more aggressive </span></span></span></span>surgical methods in these patients.</span></div></div>","PeriodicalId":14332,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":"55 2","pages":"Pages 165-171"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0