International Journal of Pharmaceutical Sciences Review and Research最新文献_第7页

A Comprehensive Guide for Analytical Method Validation 分析方法验证综合指南

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.002

G. Sai Teja, D. Archana, B. Srinu, SK. Abbas Ali, S. Siva Narayana Reddy, SK. Parvez, P. Srinivasa Babu, P. Ravi Sankar

引用次数: 0

A Review on Colon Drug Delivery Systems 结肠给药系统研究进展

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.004

Karra Geetha, Sara Akshitha, T. Rama Rao

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Current Updated Review on Prevention and Management of Conjunctivitis: A Comparative Study of Herbal and Pharmaceutical Management 结膜炎的预防与管理:草药与药物管理的比较研究

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.009

Pranali P. Holey, Pranali R. Gajbhiye, Anil P. Dewani, Nitin B. Kohale, Nikita P. Aware

引用次数: 0

Formulation Development of Antimicrobial Nail Lacquer by Transungual Delivery System for the Treatment of Paronychia 经口给药治疗甲沟炎抗菌甲漆配方的研制

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.024

Muthukumar M, Prabhu R, Rajeev T, Arunpandiyan J, Thaila R, Jayalakshmi B, Senthilraja M

引用次数: 0

Formulation and Optimization of Fast Dissolving Film Containing Rizatriptan Benzoate 苯甲酸利扎曲坦速溶膜的制备及优化

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.006

Shubham N. Gharat, Yogeshwary M. Bhongade, Anand D. Sawkare

{"title":"Formulation and Optimization of Fast Dissolving Film Containing Rizatriptan Benzoate","authors":"Shubham N. Gharat, Yogeshwary M. Bhongade, Anand D. Sawkare","doi":"10.47583/ijpsrr.2023.v82i02.006","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.006","url":null,"abstract":"Fast-dissolving films are developed to overcome difficulty with swallowing which encountered not only in pediatric or geriatric populations but also in the case of handicapped, mentally retarded or bedridden patients. The present study was aimed to formulate fast dissolving film to enhance bioavailability and to avoid first pass effect. The key is to develop successful fast dissolving film by solvent casting method and select right compatible excipients using FTIR and DSC study. The present study describes formulation, optimization and evaluation of fast dissolving film of rizatriptan benzoate in which physical and mechanical parameter such as appearance, thickness, folding endurance, surface pH, disintegration time, in-vitro drug release was evaluated. The formulation was optimized by Box-Behnken design using Design Expert software. The effect of film-forming polymer composition and plasticizer concentration on disintegration time and in-vitro drug release behavior were investigated. The F8 batch was an optimized formulation with less disintegration time of 09 seconds and high in-vitro drug release of 99.58%","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial Effects of Five Essential Oils Plant on Multidrug Resistant Bacteria Responsible for Urinary Infections 五种植物精油对泌尿系统感染多药耐药菌的抑菌作用

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.018

Haseera. N, Baskaran. K, Shalet Varghese, Nirmala Devi. N, Arifa P.P, Rathi MA

引用次数: 0

Preparation and Evaluation of Transdermal Patches of an Anti-inflammatory Drug 抗炎药透皮贴剂的制备与评价

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.019

Jalajakshi. M. N, V. Chandrakala, S. Srinivasan

{"title":"Preparation and Evaluation of Transdermal Patches of an Anti-inflammatory Drug","authors":"Jalajakshi. M. N, V. Chandrakala, S. Srinivasan","doi":"10.47583/ijpsrr.2023.v82i02.019","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.019","url":null,"abstract":"Objective: The objective of the present study was to compare the release effect of Etodolac from different polymeric (hydrophilic and lipophilic) patches prepared by varying concentrations. The best polymeric combination was selected based on the release of the drug from the patches. Methods: Polymers such as HPMC, MC, EC, PVA, Eudragit L-100, and Glycerin was used as a plasticizer. Permeation Enhancers used is Dimethyl Sulfoxide. Transdermal patches were prepared by using the solvent casting technique. FTIR was studied to estimate the incompatibility. Patches were evaluated for physicochemical Characteristics like thickness, weight variation, folding endurance, moisture loss, moisture absorption, water vapor transition, drug content, and In-vitro diffusion studies. Results: The results obtained showed no physical-chemical incompatibility between the drug and the polymers. MC: EC was found to be a suitable polymer compared to other prepared polymeric combinations in the preparation of transdermal patches. From the evaluation of patches F6 containing (1:3) % of MC: EC was considered the best formulation for the transdermal delivery of Etodolac. Conclusion: Transdermal patches were successfully prepared for Etodolac and their evaluation studies of each dosage form revealed that topically applied Etodolac patches possess immense potential to control the release rate of medicament to improve the bioavailability as well as patient compliance.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bisphenol S (BPS) Alters Xanthine Oxidoreductase Activity to Elevate Oxidative Stress Mediated Protein Carbonylation in Small Intestine of Rat ex vivo 双酚S (BPS)改变黄嘌呤氧化还原酶活性提高大鼠小肠氧化应激介导的蛋白质羰基化

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.021

Debarati Roy, Mousumi Dutta, Sourapriya Mukherjee, Goutam Paul

引用次数: 0

Screening of Different Extraction Methods for Quantitative and Qualitative Analysis of Antioxidants and Assessment of Free Radical Scavenging Activity in Morinda citrifolia L. 桑叶中抗氧化剂不同提取方法的筛选及自由基清除活性评价

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.001

Anjali Anjali, Pushpendra Pushpendra, Vimala Yerramilli, Ishwar Singh, Rup Narayan

{"title":"Screening of Different Extraction Methods for Quantitative and Qualitative Analysis of Antioxidants and Assessment of Free Radical Scavenging Activity in Morinda citrifolia L.","authors":"Anjali Anjali, Pushpendra Pushpendra, Vimala Yerramilli, Ishwar Singh, Rup Narayan","doi":"10.47583/ijpsrr.2023.v82i02.001","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.001","url":null,"abstract":"The interest of scientists and medical professionals in herbal medicinal products containing phytochemicals derived from plants is growing daily due to the shift of consumers’ preferences from convenience to environmental sustainability. One plant utilized in many medicines is Morinda citrifolia L., a tree commonly used in folk medicine, health supplements and immune-boosting products. In this study, Bioactive compounds from M . citrifolia were extracted using conventional methods and modern methods (Ultrasound-Assisted, Microwave Assisted, Water bath Assisted, Shaker Assisted, Soxhlet Assisted and Magnetic Stirrer Assisted Extraction). This study screens a variety of extraction methods used to extract active compounds: total phenolic content and antioxidant properties through DPPH, ABTS and FRAP from different parts of M. citrifolia . The results indicate that the total phenolic content and FRAP activity were highest in all parts of the plant in Soxhlet Assisted extraction. In contrast, Microwave Assisted extraction showed high DPPH and ABTS activity. This study offered valuable details on the effective phytochemical extraction processes from various parts of Morinda citrifolia L.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Clinicopathological Study of Inflammatory Dermatoses 炎症性皮肤病的临床病理研究

International Journal of Pharmaceutical Sciences Review and Research Pub Date : 2023-10-01 DOI: 10.47583/ijpsrr.2023.v82i02.017

Prasanthi Cherukuri, Vasundara Gardas, Sanjana Nutakki

{"title":"A Clinicopathological Study of Inflammatory Dermatoses","authors":"Prasanthi Cherukuri, Vasundara Gardas, Sanjana Nutakki","doi":"10.47583/ijpsrr.2023.v82i02.017","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.017","url":null,"abstract":"Introduction: The instant pattern recognition seen in neoplastic, and few infectious disorders is not seen in inflammatory dermatoses. An overall assessment of the clinical features and microscopic features aids in the diagnosis of inflammatory lesions which have several overlapping features in common. Inflammatory dermatoses include psoriasiform diseases, lichenoid diseases, vasculopathic diseases, spongiotic diseases and vesiculobullous diseases. Aim: The current study is aimed to evaluate the pathological findings in inflammatory skin lesions and to compare with the pathological with clinical findings. Material and methods: This is a study conducted at GITAM institute of medical sciences and research for a period of 18 months i.e., from January 2022 to June 2023. All the skin biopsies received at the department of pathology, GIMSR. Using 10% formalin they were subjected to fixation and processed in automatic tissue processor and after taking 3-4 microns sections, staining was done with eosin and hematoxylin and a final histopathological diagnosis was made. Results: The patterns of various tissue reactions were observed in our study were Lichenoid reaction pattern (23%), Psoriasiform reaction pattern (39%), Spongiotic reaction pattern (22.7%), Vesiculobullous reaction pattern (4.5%), Vasculopathic reaction pattern (7.9%).In our study the most common inflammatory dermatoses observed was psoriasis 26% (23 cases), variants of lichen planus 12.5% (11 cases), pityriasis Rosea 6.8% (6 cases) followed by 5.6% (5 cases) spongiotic dermatitis and leucocytoclastic vasculitis each. In 72 cases (82%) there was agreement between the clinical and histological diagnoses, whereas in 16 cases (18%) there was a discrepancy. Conclusion: To narrow the differential diagnosis and arrive at the most accurate diagnosis, a systematic approach during histopathological assessment and sorting inflammatory dermatoses based on the reaction pattern are crucial.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0