International Journal of Reproductive Medicine and Sexual Health最新文献

{"title":"Efficacy and safety of the combination nifuratel-nystatin and clindamycin-clotrimazole, in the treatment of bacterial vaginosis. Randomized controlled clinical trial","authors":"F. E. L. Hoz","doi":"10.36811/ijrmsh.2021.110010","DOIUrl":"https://doi.org/10.36811/ijrmsh.2021.110010","url":null,"abstract":"Introduction: Bacterial vaginosis (BV) is the most frequent gynecological infection in women of reproductive age, thus driving the search for effective and safe treatments.\u0000\u0000Objective: To compare the efficacy and safety of the combination nifuratel-nystatin and clindamycinclotrimazole, in the treatment of bacterial vaginosis.\u0000\u0000Materials and Methods: Randomized controlled clinical trial in 147 single women (18 to 39 years old), non-pregnant and sexually active, with a diagnosis of BV according to the Amsel clinical criteria and the Nugent score; between 2016 and 2018. In a highly complex private clinic in Armenia, Colombia. Women were randomized into two groups: \"A\" (73 participants: nifuratel (500 mg) - nystatin (100,000 IU) and \"B\" (74 participants: clindamycin (100 mg) - clotrimazole (200 mg)); both groups were treated with vaginal ovules, \"A\" for six days and \"B\" for three days. All participants were followed-up for clinical and microbiological healing at 7 and 30 days, respectively, after completion of treatment, the STATA® 14.0 program was used.\u0000\u0000Results: The mean age of women was 28.35±5.79 years. The clinical cure rate with the nifuratelnystatin combination was 93.15%, and that of clindamycin-clotrimazole 97.29%, (p=0.123). The microbiological cure rate with the nifuratel-nystatin combination was 87.67%, and that of clindamycin-clotrimazole 93.24%, (p=0.102). Regarding safety, there were also no significant differences between the two groups (p=0.144); Mild adverse reactions were observed. Recurrence in group \"A\" was 12.32% compared to 6.75% in group \"B\" (p>0.05).\u0000\u0000Conclusions: In this study, the combinations nifuratel (500 mg) -nystatin (100,000 IU) and clindamycin (100 mg)-clotrimazole (200 mg), reported that both are equally effective and safe options in the treatment of BV. It is necessary to evaluate the effect and safety of other combinations in order to implement timely interventions.\u0000\u0000Keywords: Vaginosis; Bacterial; Efficacy; Safety; Nifuratel; Nystatin; Clindamycin; Clotrimazole.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81271174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Physiological Changes During Pregnancy","authors":"Siniša Franjić","doi":"10.36811/ijrmsh.2019.110006","DOIUrl":"https://doi.org/10.36811/ijrmsh.2019.110006","url":null,"abstract":"Every adult woman is responsible for their body, and the decisions they make have an impact on their life and their health. However, there are times in life, pregnancy, when a person is deeply responsible for a new life in development. Safe signs of pregnancy are the presence of a fetus seen by ultrasound, listening to heart tones, touching parts of the fetal body and the presence of pregnancy hormones in the urine. After fertilization, measurable concentrations of hCG begin to emerge in the body after 7-10 days, which can be evidenced from the urine or blood of the woman. The immunological tests used today are mostly based on the use of latex particles. The presence of Human chorionic gonadotropin, the polypeptide beta subunit of which is used to prove pregnancy (abbreviated b-hCG) at a concentration of 25 mIU in the urine of a woman, equivalent to a period between the fourth and fifth weeks of pregnancy, can be demonstrated. A planned pregnancy presupposes a series of procedures that will contribute to the proper and complete development of the embryo. Each stage of pregnancy brings certain biological changes in the body of the woman. Pregnancy should last a minimum of 37 weeks, but it can take up to 42 weeks.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82901322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy Evaluation of Standardized Fenugreek seeds extract as Furostanolic Saponins & Myo-Inositol (Nutricyst-M) in Management of Insulin Resistance (IR) & Ovary Volume in PCOS Subjects","authors":"A. Jaipuriar, A. Malik, G. Lamgora","doi":"10.36811/ijrmsh.2019.110004","DOIUrl":"https://doi.org/10.36811/ijrmsh.2019.110004","url":null,"abstract":"Polycystic ovarian syndrome (PCOS) currently affects nearly 6-10% of women of reproductive age. A frequent feature of women with PCOS is insulin resistance accompanied by compensatory hyperinsulinemia, and increasing evidence suggests that hyperinsulinemia plays an important role in the pathogenesis of PCOS, pointing the way to new and novel therapy for PCOS. The study was planned with one natural alternative remedy Standardized Fenugreek seeds extract as FurostanolicSaponins and Myo-Inositol.Standardized Fenugreek seeds extract as Furostanolic saponins which contains bioactive components Saponins extracted from Fenugreek seeds improves insulin sensitivity and, in turn, may regulate circulating androgen levels. It improves insulin-mediated glucose\u0000\u0000disposal in women with PCOS [1,2]. It also decreased theLuteinizing HormoneLH/FSH (Follicle- Stimulating Hormone) ratio as observed in my last study [2-4]. Myo-inositol not only improves fertility by lowering male sex hormones in both, women with and without PCOS but it could also improve ovulation in women with PCOS. In addition, Myo-inositol also reduces insulin resistance and increases estrogen levels. Myo-inositol reduced testosterone, LH, and insulin levels. The present observation study is to establish efficacy and safety in management of IR and ovarian volume.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88468573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Female Sexual Dysfunction","authors":"Siniša Franjić","doi":"10.36811/IJRMSH.2019.110003","DOIUrl":"https://doi.org/10.36811/IJRMSH.2019.110003","url":null,"abstract":"If a woman finds that she has a problem in sex life, if they are interfering with these relationships, it is definitely a moment to visit a doctor. Initial problems can in most cases be successfully monitored; By advancing the problem they will only accumulate, and inter-party relations will irreversibly be disrupted. It would be ideal to apply an interdisciplinary approach to treatment, meaning to include specialists of various specialties, such as gynecologists, psychiatrists, psychologists, general practitioners and others. Of course, treatment, or therapeutic approach, will be adjusted to the root cause. In treatment should be considered estrogenic creams, modification of basic therapy, psychotherapy and medicaments according to the recommendation of a psychiatrist, physical exercise etc.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77873156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is induced abortion becoming a family planning method in Ghana?: A situational analysis of induce abortion and contraception uptake in two urban cities of Ghana","authors":"F. Y. Gbagbo, Josephine Akosua Gbagbo","doi":"10.36811/IJRMSH.2019.110002","DOIUrl":"https://doi.org/10.36811/IJRMSH.2019.110002","url":null,"abstract":"Background: Following amendment of Ghanaian abortion law in 1985, abortion services became more available as permitted by law. Services data however remain scares due to provider and facility stigmatization.\u0000\u0000Objective: To explore the use of abortion as a family planning option using provider reports, trends of contraception and induced abortion service uptake in facilities within two urban cities in Ghana.\u0000\u0000Methods: Cross-sectional, descriptive design, using facility data from 50 private (42) and Non-Governmental Organizations (8). Ten in-depth interviews were also held with midwife providers (6) and medical officers (4) between January 2010 and December 2017 in Accra and Kumasi Metropolises.\u0000\u0000Results: Facility patronage of abortion services in Accra and Kumasi Metropolises increase steadily each year with contraception uptake. Abortion services in NGO facilities were however reported as target driven and providers’ performances/bonuses were tied to meeting set targets thereby encouraging abortion on demand. Whereas NGO facilities provide both abortion and full contraception method mix, majority (38 out of 42) of private facilities provide only abortion services. Those providing contraception focus mainly on short term methods (pills and injections) due to lack of interest and/or trained providers. There are more midwife lead abortion providing facilities in Accra (40) than in Kumasi (10). Where midwives provided abortion services, contraceptives were readily available and clients encouraged to take a method following abortion. This practice was very common in NGO facilities as post abortion contraception was reported to be a mandatory package.\u0000\u0000Conclusions: The Ghanaian abortion law allows conditional abortion and not on demand. However, increasing numbers of abortions in the study area coupled with reported target setting for abortion services suggest abortion on demand and its being used as a family planning option. A nationwide facility based assessment of abortion and contraception service delivery is recommended to inform policy.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83747069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robson’s class and caesarean scar defects","authors":"C. Alovisi, R. Amadori, C. Alovisi, D. Surico","doi":"10.36811/IJRMSH.2019.110001","DOIUrl":"https://doi.org/10.36811/IJRMSH.2019.110001","url":null,"abstract":"Caesarean scar defect (CSD) may lead to the occurrence of gynecologic symptoms such as abnormal uterine bleeding secondary to intermittent passage of retained menstrual blood within the CSD pelvic pain, and infertility. This prospective cohort study was conducted at the Department of Obstetrics at Maria Vittoria Hospital in Turin (Italy), from January 2013 to December 2013 to analyze the effects of two different suturing techniques (single layer and double layer closure of the hysterotomy) and Robson's class impact on the incidence of CSD. All procedures were performed using a modified Stark technique by the same single senior surgeon. The way of closure of the uterine incision was alternated every three months, in order to have two groups of partecipants: one with a single layer and the other with a double layer closure technique. Single layer was carried out as one continuous locking stitch; double layer was performed with a first closure identical to the single layer and an additional suture with a continuous unlocked stitch used to imbricate the first layer. Both ways of closure of the uterine incision were performed using monofilament synthetic absorbable polydioxanone suture. Twelve months after their caesarean section, the women had an ultrasound examination of the uterine scar performed by a single experienced operator blinded to suture technique and the Robson class. The trial recruited 85 cases. 21 patients (24.8%) belonged to Robson's class 1, 5(6%) to class 2, 1(1.3%) to class 4, 35(41%) to class 5, 13(15.4%) to class 6, 6(7%) to class 7, 4(4.5%) to class 8. During the ultrasound follow up we found 10 CSD (11,8%): 8/10 CSD (80%) were found in Robson's class 5, 1 in class 1 and 1 in class 6 (p 0.008), with no correlation with single- or double-layer suture (p 0.141). To our knowledge, no previous studies evaluated the correlation with Robson classification and CSD.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87784623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fertility regulation","authors":"Siniša Franjić","doi":"10.36811/ijrmsh.2019.110005","DOIUrl":"https://doi.org/10.36811/ijrmsh.2019.110005","url":null,"abstract":"Ovarian cells or the number of incompetent ovarian cells that may lead to pregnancy is reduced. At a certain age, for example, after 40 years of age, naturally reduces the possibility of conception also the possibilities of spontaneous abortion and anomalies. Fertility of men and women also depends on life habits, the presence of certain illnesses, the enjoyment of various opiates, etc. Unhealthy lifestyle, poor nutrition and obesity are also factors that reduce fertility in men and women. An average, healthy couple it is necessary six to Fertility of men and women depends primarily on their age. In women, for example, the number of twelve months of active endeavours to conceive of pregnancy. If pregnancy does not occur during this period, it is necessary to seek medical help.","PeriodicalId":14247,"journal":{"name":"International Journal of Reproductive Medicine and Sexual Health","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81830189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}