Journal of Istanbul Veterinary Sciences最新文献

{"title":"Is it possible to change milk secretion of drugs with soy enriched diets in lactating ruminants?","authors":"Yiğit Güneş","doi":"10.30704/http-www-jivs-net.1142811","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1142811","url":null,"abstract":"Soy is the most commonly used protein supplement in beef and dairy diets. Soy, which is also used as a common protein source in animal feed, is palatable and has a good amino acid balance and high bioavailability. In vivo and in vitro interaction of flavonoids, including isoflavones such as genistein and daidzein, with several ABC transporters, including breast cancer resistance protein (BCRP/ABCG2), has been demonstrated. BCRP presence in ruminants could affect the efflux of hydrophobic toxins and drugs, including their active secretion to milk and a reduction in the withdrawal time of the drug milk residues. As a result of inhibition of efflux transporters such as BCRP, changes in drug pharmacokinetics and drug transfer into milk have been observed. In this respect, the use of forage supplemented with BCRP inhibitors may be beneficial to control drug accumulation in milk and prevent undesirable contamination of milk. It is aimed to reduce the drug withdrawal periods for dairy animals with the procedure in question. In this review, it is aimed to give information about the importance of soy-enriched diets in the nutrition of ruminants during the lactation period and the effect of transport proteins on the transfer of drugs into milk.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125015267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A morphological study on sinus and atrioventricular nodes in saanen goats*","authors":"Sedef SELVİLER SİZER, Y. Kabak, M. Kabak","doi":"10.30704/http-www-jivs-net.1201093","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1201093","url":null,"abstract":"In mammals, the sinus node and atrioventricular node are defined as the heart's specific stimulus and conduction systems. The electrical stimulation that starts in the sinus node continues with the atrioventricular node, and the rhythmic stimulation occurs in this way. There are differences in the sinus and atrioventricular nodes' location, size, and cell structures between species. In this study, which was carried out to determine the morphological structures and locations of the sinus and atrioventricular nodes in Saanen goat hearts, nine hearts from healthy goats were used. After performing the routine tissue follow-up procedure for histological examinations, 5 μm-thick serial sections taken from paraffin-blocked samples were stained with Crossman Trichrome and Periodic Acid Schiff (PAS) and photographed. It was determined that the sinus node was in a subepicardial position near where the cranial vena cava opens up to the right atrium. The sinus node, with an average length of 8-10 mm was crescent-shaped. The atrioventricular node was located in the subendocardium layer in the right half of the interatrial and the interventricular septum, where the coronary sinus opened into the right atrium. An atrioventricular node with an average length of 4.5-5 mm was observed to be roughly oval. Two types of cells were identified in both nodes: cells with small, rounded with empty cytoplasm and rather large nuclei, and cells with thin, elongated structures and darker staining.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133062183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological and clinical approach to plant based complementary health products in lower urinary system diseases in cats and dogs","authors":"Yiğit Güneş, Ceren Anlas, B. Dokuzeylül","doi":"10.30704/http-www-jivs-net.1150072","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1150072","url":null,"abstract":"Medicinal plants, which are widely used in the treatment of many diseases in folk medicine, are alternative treatment approaches that allow to overcome the limitations of modern treatments such as high treatment costs and difficulty in accessing health services. In addition to their traditional uses, the World Health Organization (WHO) also recommends the use of medicinal plants as alternative applications, especially in countries where have limited access to modern medical facilities. Limitations on the methods used in the treatment of lower urinary tract diseases such as urinary tract infection and urolithiasis in both human and veterinary practice (high treatment cost, low tolerability, development of antibacterial resistance, etc.) have brought the use of natural products of herbal origin within the scope of supportive/complementary treatment approaches. Although the mechanism of action of medicinal plants in the treatment of lower urinary tract diseases is not clearly known, studies have shown that they increase the glomerular filtration rate; and they can be complementary alternatives to conventional treatment due to their anti-lithogenic, antibacterial, antioxidant and anti-inflammatory activities. Patients that referred to with one or more of the symptoms of urinary system diseases such as polyuria, pollakiuria, dysuria, stranguria, anuria, hematuria, urinary incontinence constitute the case group of one of the first three systemic diseases most frequently brought to the clinic. Failure to intervene in the diseases shaped in the lower urinary system in a timely manner causes negative consequences such as the disease becoming chronic, the progression of the disease to the upper urinary system in progressive cases, and a decrease in the quality of life. Complementary products used in addition to medical treatment are sometimes used for prophylactic purposes. In this context, many supplements have been prescribed for different diseases in small animal practice in recent years.  In this review, it is aimed to convey current developments about medicinal plants, which are used effectively within the scope of supportive treatment practices in lower urinary system diseases of cats and dogs, to veterinary clinical practice.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125855207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exemplifying ‘pathobiome’ concept through case study: Co-infection with Vibrio harveyi, Photobacterium damsela and Cryptocaryon irritans in Salema (Sarpa salpa)","authors":"H. Yavuzcan, F. Seçer, Bilgenur HARMANŞA YILMAZ, Münir Ahmet Tunar","doi":"10.30704/http-www-jivs-net.1128614","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1128614","url":null,"abstract":"A pathobiome approach has been revealed as a set of organisms (i.e. prokaryotic, eukaryotic, and virus associations) in the aquatic environment that interact with the host (fish) to cause disease. The approach of the one pathogen–one disease is not wholly satisfactory to comment on the impairment of health status and disease process in fish. To exemplify the pathobiome concept, we present a fish disease in which more than one pathogen and possible synergistic interaction of inadequate water quality. In this case, the heavy mortalities were observed in Salema (Sarpa salpa) from an exhibition aquaria. Bacterial identification with matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF MS) showed the pathogen bacteria species of vibrio and photobacterium. In the parasitic examination, the invasion of marine ciliata, Cryptocaryon irritans was observed in the diseased fish. Moreover, poor water quality was considered as contributing factor to disease emergence in this case. The co-existence of pathogen Vibrio species (Vibrio harveyi) and Photobacterium damsela with its subspecies (subsp. damsela and subsp. piscicida) as well as marine ciliata, C. irritans for a description of a disease picture in a marine fish species are reported for the first time, providing an example of a pathobiome paradigm.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114215925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Could polymerase chain reaction be an alternative diagnostic method for dermatophytes?","authors":"Semih İzmi̇rli̇, Deniz Zeynep Telci̇, M. Or, B. Dokuzeylül","doi":"10.30704/http-www-jivs-net.1184780","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1184780","url":null,"abstract":"Dermatophytosis are cutaneous mycoses caused by Microsporum spp., Trichophyton spp. and Epidermophyton spp. dermatophytes. Dermatophytosis resembles other skin diseases due to its various clinical manifestations such as multifocal alopecia, circular lesions, scaling, crusting, papular and pustular lesions, follicular obstruction, erythema, hyperpigmentation, miliary dermatitis and dystrophic nail growth, and its diagnosis is based on the use of many different methods. Generally used methods; clinical appearance, microscopic examination, examination with Wood's lamp and mycological culture but these methods have some disadvantages. Microscopic examination requiring expertise, fast and cost-effective method, but in some cases, microbiologists encounter specimens that are microscopically negative but give positive results in mycological culture. Examination with Wood's lamp can only be used for the diagnosis of M. canis and its specificity is low. On the other hand mycological cultures require a long time (3-6 weeks) to give definitive results, and their sensitivity may decrease due to common contaminant growth. Considering these reasons, new polymerase chain reaction (PCR) based methods have been developed for the diagnosis of dermatophyte agents. Compared to other molecular methods, the PCR method is easy, fast and applicable for the identification of dermatophyte species that do not show typical morphological features. Although PCR-based diagnostic methods are widely used in humans in the diagnosis of dermatophytosis, its usefulness in dogs and cats has also been confirmed. As a result, the PCR method used in the diagnosis of dermatophytosis; it is emphasized that it can be used in the diagnosis of dermatophytosis due to the ease of obtaining samples, providing faster results compared to mycological culture, and not requiring expertise, and it is emphasized that new and different methods should be used in the diagnosis of diseases. In this study, it was aimed to demonstrate the effectiveness of the PCR method and its applicability in clinical practice, as well as mycological culture, which is frequently used in the diagnosis of dermatophytosis.   ","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"9 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124178625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of neutralising antibodies against SARS-CoV-2 in companion animals in Istanbul","authors":"Hakan Enül, F. Sarac, Cumhur Adıay, S. Uzar, P. Tuncer-Göktuna, S. Arun, M. Hasöksüz","doi":"10.30704/http-www-jivs-net.1198979","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1198979","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and rapidly spread throughout the world. After the susceptibility of various animals to SARS-CoV-2 infection was reported, the prevalence of COVID-19 infection in pet animals and their role in virus transmission became a source of concern. Seroprevalence of SARS-CoV-2 in pet animals has been reported from various parts of the world to date. In this study, 206 serum samples of household dogs and cats were obtained from a diagnostic laboratory in Istanbul. Ninety-nine of the samples were collected during the second wave (November and December 2020) of the pandemic, and 107 were collected between August and September 2021. Neutralizing antibodies against SARS-CoV-2 in companion animals was investigated by virus neutralization test. Among the 99 serum samples which were collected during the second wave (November and December 2020) of the pandemic, while no neutralizing antibodies were found in 61 sera of cats, one of 38 dogs was positive with a titer of 1/256. Similarly, 0/54 cats and 1/53 dogs were tested positive for the neutralizing antibodies among the samples collected between August and September 2021. This study is demonstrating the evidence of SARS-CoV-2 infection in dogs. ","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122638912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of dietary fiber in animal diet; a mini review","authors":"Pradeep Chaudhary, Bishwo Jyoti Adhi̇kari̇, Jenish Adhi̇kari̇","doi":"10.30704/http-www-jivs-net.1125539","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1125539","url":null,"abstract":"This mini review describes dietary fibers, their source and compositions. It explores the importance of fiber in the animal diet, health benefit and how fiber contributes to the production of healthy animals in post antibiotics era. The review also discusses fiber fermentation, role in nutrient digestion, enzyme production and how the gut microbiota responds to a selection of fibers. And the components of fiber that increases microbiota which are commensal to the mucus and epithelium of gut. Lastly, recommendations are made on how dietary fiber could be used to achieve maximum advantages in terms of nutrient utilization, performance, and gut health in both monogastric and ruminant animals. ","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"136 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131335366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The electrocardiographic changes generated by centrally applied arachidonic acid in rats","authors":"Esra Kasikci, M. Yalçın","doi":"10.30704/http-www-jivs-net.1175674","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1175674","url":null,"abstract":"Arachidonic acid (AA) and its metabolites have multifunctional regulatory effects on the central nervous system. Our previous reports disclosed that centrally injected AA organized the cardiovascular system in normal or hypotensive conditions by regulating the central and peripheral mechanism. In the light of the knowledge of the potential cardiovascular effects of AA, the current study aimed to investigate the effects of intracerebroventricular (ICV) injected AA on the electrocardiography (ECG) of the anesthetized rats. The adult Sprague Dawley rats were anesthetized with ketamine and xylazine mixture (50 mg/kg and 20 mg/kg; i.m., respectively). Under the anesthesia, the guide cannula was inserted into the left lateral ventricle of the rats. The ECG traces obtained from the lead II were written by placing electrodes on the limbs of the rats. Centrally injected AA (150 μg; ICV) statistically significantly (p<0.05) caused to the lengthening of the ECG waves and intervals, resulting in a decrease in the heart rate of the rats without changing the ECG waveforms, the amplitude, and also the isoelectric line. The obtained results clearly show that centrally injection of AA caused the deceleration in the heart electrical activity. The deceleration in the electrical activity of the heart caused to show bradycardia in the rats by extending the duration of the ECG waves and intervals.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116267431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on toxin genes and cytotoxity levels of Bacillus cereus in various ready to eat foods and pastry products in Turkey","authors":"B. Çöl, H. Aksu","doi":"10.30704/http-www-jivs-net.1198813","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1198813","url":null,"abstract":"Bacillus cereus is a spore-forming and toxin-producing gram-positive bacteria widely isolated from soils, meat, milk, and vegetables. It is recognized as one of the pathogenic bacteria that can lead to food poisoning and food spoilage in food service systems due to its ease of contamination of foods and lack of guarantee of elimination by pasteurization and sanitation practices. B. cereus causes two types of diseases mainly characterized by diarrhea and vomiting type syndrome with the toxins it produces. Toxins produced by B. cereus are mainly heat-stable emetic toxins and three different heat-labile enterotoxins. Foodborne illnesses of the diarrheal type are caused by the single proteins cytotoxin K (CytK), hemolysin BL (Hbl), and non-hemolytic enterotoxin (Nhe), whereas those of the emetic type, are caused by an emetic toxin. In this study, 225 ready-to-eat foods and pastry products were analyzed for B. cereus, its toxin profiles and cytotoxicity effect. Multiplex PCR is used to identify the presence of the Hbl, Nhe, CytK, and emetic toxin encoding genes. Component-specific antibody-based ELISA tests were utilized to determine the Hbl-L2 and NheB components. Cytotoxic activity of the B. cereus isolates on Vero cells was also identified. In total, B. cereus was detected in 36 out of 225 (16%) food samples. From the positive 36 B. cereus isolates, the ces gene was not identified, whereas 94.4% (34) Nhe, 58.3% (21) Hbl, and 5.5% (2) CytK encoding genes revealed positive results on PCR analysis. PCR results were also compatible with ELISA and Cytotoxicity tests. In a nutshell, 16% prevalence of B. cereus in foods is insufficient, and the presence or absence of toxin genes may not yield reliable results. It is critical to detect pathogenic B. cereus toxin gene profiles as well as toxin production ability at the same time. This study presents for the first time, data from a cell culture cytotoxicity test using specific monoclonal antibody-based sandwich ELISA and multiplex PCR for ready-to-eat foods and pastry products in Turkey.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"281 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116078666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clues for zoonotic potential and transmission of Sars-CoV-2 via food and water","authors":"Ahmet Gökhan Coşkun, S. Temelli, A. Eyigör","doi":"10.30704/http-www-jivs-net.1072726","DOIUrl":"https://doi.org/10.30704/http-www-jivs-net.1072726","url":null,"abstract":"As a result of the COVID-19 pandemic caused by the SARS-CoV-2 virus, which emerged from Wuhan, China in 2020, economic, social, and psychological problems occurred all over the world, mandating implementation of strict curfew, quarantine, travel restriction measures, and vaccinations against the virus. Though the source of the virus was not clearly revealed, initial case reports from a market in Huanan selling animal products, coupled with sequence analyses of the isolates, revealed close similarity to coronavirus isolated from bats (RatG13) and pangolins, questioning the suspect source of SARS-CoV-2 as zoonotic. Additionally, epidemiological and experimental studies indicated the presence of SARS-CoV-2, and its specific antibodies in many animals such as cats, dogs, ferrets, calves, and deer. Besides, determination detecting the virus in water samples including treated waters from wastewater treatment plants, fecal shedding, and possible fecal-oral transmission of the virus gained importance. Accordingly, vegetables and fruits irrigated with contaminated water, and foods such as shellfish grown in contaminated waters had the risk of carrying the virus. Although one of the most effective ways for protection against SARS-CoV-2 is mass and booster vaccinations, the emergence of new variants raises concerns on vaccines’ effectiveness against these variants. Thus, urgent implementation of one health concept addressing human, animal, and environmental health as a whole is mandatory to overcome this and other possible future pandemics. In this article, emergence, spread, zoonotic potential, fecal-oral transmission risk, and the possible role of food and water in the transmission of the SARS-CoV-2 virus were reviewed based on up-to-date published data.","PeriodicalId":142259,"journal":{"name":"Journal of Istanbul Veterinary Sciences","volume":"2014 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128832436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}