International Journal of Research in Medical Sciences最新文献

{"title":"Efficacy of Dr. SKS hair booster serum for the treatment of hair loss in COVID-19 induced persistent telogen effluvium","authors":"Stuti Khare","doi":"10.18203/2320-6012.ijrms20240837","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240837","url":null,"abstract":"Background: Excessive hair shedding occurs in patients with coronavirus disease 2019 induced telogen effluvium. Dr. SKS hair booster serum has demonstrated encouraging benefits in different types of alopecia in previous studies. We sought to evaluate the efficacy of Dr. SKS hair booster serum for the treatment of COVID-19 induced persistent TE.\u0000Methods: A total of 500 patients aged 18 to 60 years who had recovered from reverse transcription-polymerase chain reaction proven COVID-19 infection but experienced sustained hair fall even after 6 months were included in the study. One millilitre of Dr. SKS hair booster serum injection was administered intradermally in scalp per session. Efficacy and safety outcomes were evaluated at baseline, 3 and 6 months after the treatment.\u0000Results: Approximately half of the patients demonstrated excellent improvement in expert panel global photographic assessment at 3 months (vertex area; 43.6% and frontal area; 46%) that was increased at 6 months (vertex area; 48% and frontal area; 50%). Each patient's clinical condition improved. All patients were satisfied with the results in terms of mean total hair growth satisfaction scale score of five aspects at 3 and 6 months treatment.\u0000Conclusions: Intradermal injection of Dr. SKS hair booster serum proves to be effective treatment for hair loss in COVID-19-induced persistent TE.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"73 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical techniques in bariatric surgery: minimally invasive approaches and long-term outcomes","authors":"Miguel Andrés Irua Veloz, Leslie Dayanna Rivera Pinto, Juan Carlos Navarrete Pérez, Andrea Gabriela Parada Marín, Henry Paúl Velasco Molina, Jean Pierre Villafuerte","doi":"10.18203/2320-6012.ijrms20240681","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240681","url":null,"abstract":"Obesity is a worldwide epidemic, and current weight loss strategies frequently do not effectively tackle the problem. Bariatric surgery effectively addresses this issue. A systematic research study was done to investigate minimally invasive bariatric operations, using 32 studies from a pool of 2,118 data. Bariatric surgery was found to greatly assist in weight reduction and enhance general health results. Procedures such as gastric balloon, gastric banding, and gastric bypass can decrease the weight of obese people and alleviate associated health conditions. Sleeve gastrectomy is highly successful and yields favorable long-term results. The procedure used relies on the patient's health and the surgeon's discretion. The primary risk factor is the recurrence of weight or the need for revision surgery. Ultimately, bariatric procedures provide weight loss and long-term health benefits, but it is important to acknowledge the associated surgical risks. Immediate dangers include of blood clotting, intestine blockage, bleeding, infections, abdominal pain, nausea, heartburn, vomiting, ulcers, and other issues associated with surgery. Long-term consequences include of dumping syndrome, starvation, and weight regain.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"87 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating maternal and perinatal outcomes of eclampsia at a tertiary healthcare facility in Bihar, India: a retrospective study","authors":"Priyanka Kumari, Swati, Ashutosh Kumar, Gunjan Gunjan","doi":"10.18203/2320-6012.ijrms20240677","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240677","url":null,"abstract":"Background: Eclampsia, characterized by seizures in women with preeclampsia, is a leading cause of mother and neonatal illness and death globally. Despite advancements in obstetric care, eclampsia remains a significant concern, especially in nations with poor and medium incomes. The aim of the study is to comprehensively assess the maternal and perinatal outcomes associated with eclampsia cases treated at a tertiary healthcare centre with the goal of improving understanding and management strategies for this serious medical condition.\u0000Methods: This retrospective observational study was conducted over 12 months. Data were collected from 200 eclampsia cases, focusing on demographic information, obstetric history, clinical characteristics, obstetric interventions, maternal complications, and perinatal outcomes. Statistical analysis was accomplished using SPSS version 21.\u0000Results: The mean age of patients was 28.5 years, with a majority (65%) being multiparous. Antepartum eclampsia was the most common clinical type (60%). Emergency caesarean section was performed in 70% of cases. Maternal complications included pulmonary edema (45%) and renal failure (25%), with a maternal mortality rate of 5%. Pre-term births occurred in 40% of cases, with an average gestational age at birth of 32 weeks. Additionally, 35% of newborns were low birth weight, and the perinatal mortality rate was 15%.\u0000Conclusions: This study highlights the substantial burden of neonatal and mother morbidity and death related with eclampsia in Bihar, India. Effective management strategies, including timely diagnosis, obstetric interventions, and preventive measures, are crucial in mitigating the adverse outcomes of eclampsia. Improving access to antenatal care, early detection of pre-eclampsia, and enhancing obstetric care services are essential in reducing the impact of eclampsia. Furthermore, continuous medical education programs for healthcare providers can enhance their knowledge and skills in managing eclampsia cases effectively.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of non-invasive scores predictive of development of metabolic dysfunction associated liver disease in patients of type 2 diabetes mellitus and evaluation of additive effect of smoking in these patients","authors":"Heena Singla","doi":"10.18203/2320-6012.ijrms20240665","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240665","url":null,"abstract":"Background: Metabolic dysfunction associated liver disease (MASLD) has been found to be at alarming increase in Indian population. Prevalence of metabolic syndrome including Type 2 Diabetes Mellitus is also increasing which may be attributed to certain lifestyle changes. In the present study, we compared the likelihood of liver fibrosis by measurement of non-invasive scores among Type 2 diabetics and smokers, Type 2 diabetics but non-smokers and healthy controls. Our study will provide useful insights to evaluate the association between Type 2 diabetes, smoking and development of MASLD.\u0000Methods: The study was done at a tertiary care hospital. Participants were divided into 3 groups (each of 40 participants) which included those with type 2 diabetes mellitus and smokers, those with type 2 diabetes mellitus but non-smokers and healthy controls. Parameters included in the database were age, sex, body mass index, history of diabetes, history of hypertension, any medication, tobacco use and alcohol consumption. Venous blood samples were taken in the morning after a 12-h overnight fasting and investigations were done. Results were recorded.\u0000Results: FIB-4 score and AST/ALT ratio was significantly higher in diabetics and smoker patients, in comparison to diabetics but non-smokers and healthy controls.\u0000Conclusions: Smoking and underlying type 2 diabetes mellitus have a synergistic effect on the severity of fibrosis, as compared to nonsmokers with type 2 diabetes mellitus. Hence smoking cessation, in addition to glycemic control with regular medication, may be beneficial in reducing the severity of MASLD among patients with type 2 diabetes mellitus.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"109 3‐4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intestinal obstruction caused by tuberculosis: unmasking a silent risk","authors":"Chandrakala Kumari, N. P. Narain","doi":"10.18203/2320-6012.ijrms20240667","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240667","url":null,"abstract":"Background: Intestinal tuberculosis (TB) remains a global health challenge, especially in regions with a high TB prevalence. This manifestation, distinct from pulmonary TB, involves the gastrointestinal tract, often leading to intestinal obstruction. The study addresses the insidious nature of the disease, emphasizing the urgency for timely diagnosis and intervention. Recognizing the multifaceted impact of TB on various organs, the study explores the pathophysiology, clinical presentation, and diagnostic complexities of intestinal TB.\u0000Methods: This study was conducted at Nalanda medical college and hospital in Patna, Bihar, India, the retrospective study spans three years focusing on 127 patients with intestinal obstruction due to TB. Inclusion criteria prioritized histopathological confirmation of TB, ensuring cohort accuracy. The study employed preliminary investigations, including hemogram, chest X-ray, abdominal X-ray, ultrasonogram, sputum examination, and Mantoux test and CECT whole abdomen. Clinical presentations were systematically analyzed, guiding tailored management protocols based on the mode of presentation.\u0000Results: Demographically, the study identified TB as the cause in 127 cases, with a balanced gender distribution and a peak incidence in the 21-30 years age group. Presentations varied, predominantly with acute symptoms. Common complaints included abdominal pain, vomiting, constipation, and distension. Surgical intervention within 24 hours was crucial in 61.1% of cases. Intraoperatively, findings comprised mesenteric thickening, lymph nodal enlargement, and adhesions. Adhesionolysis was the primary procedure. Postoperative complications, mainly wound infections, were noted but had a limited impact on mortality.\u0000Conclusions: This study reveals TB as a significant contributor to intestinal obstruction, emphasizing challenges in early diagnosis. Adhesionolysis emerges as a key operative procedure, underscoring the need for surgical flexibility. Postoperative complications, while notable, have minimal impact on mortality.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"22 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140258182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of genital pruritus in female patients attending the dermatology OPD at a tertiary care center in South Rajasthan","authors":"Renjana S., A. Mittal, Manisha Balai","doi":"10.18203/2320-6012.ijrms20240666","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240666","url":null,"abstract":"Background: Genital pruritus is a common complaint among women, the cause of which could be multitude. Identification of these causes can lead to prompt resolution of pruritus with appropriate therapies. The objective of our study was to determine the clinical profile of genital pruritus and its impact on quality of life amongst all female patients attending Dermatology OPD at our tertiary care centre.\u0000Methods: An observational, descriptive, cross-sectional study conducted from June 2020-May 2021on 196 female patients attending the dermatology OPD with primary complaints of genital pruritus. Diagnosis was established by history and clinical examination and confirmed by bed side tests and laboratory investigations as and when required.\u0000Results: The mean age of the patients was 36.87±15.24 years with 41.8% in the age group of 18-35 years. In majority (47.4%) of patients, itch was of moderate severity according to the Numerical rating scale. Infectious diseases (45.9%) were the most common cause followed by inflammatory (33.2%), idiopathic (19.4%) and hormonal (1.5%). Vulvovaginal candidiasis was by far the commonest (36.2%). The most common inflammatory dermatoses were lichen simplex chronicus (12.2%) followed by lichen sclerosus atrophicus (10.2%) and contact dermatitis (6.1%). 7 patients with idiopathic itch were diagnosed to have an underlying psychiatric illness.\u0000Conclusions: As genital pruritus has multiple causes, proper categorization and diagnostic evaluation would be appropriate to achieve optimal treatment to meet the diverse needs of women who suffer from it.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"100 S104","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitude and practice on dengue among residents of tribal hostel in Bilaspur: a cross-sectional study","authors":"Vivek Sharma, Nasarin Parveen, Darwin Deissuza","doi":"10.18203/2320-6012.ijrms20240324","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240324","url":null,"abstract":"Background: In the present era, vector-born disease accounts for 17% of the estimated global burden of all infectious diseases. One such deadly vector-borne disease is dengue. Dengue, dengue hemorrhagic fever, and dengue shock syndrome are major international public health concerns; 2.5 billion people live in high-risk dengue areas with 50 million dengue infections worldwide annually. Aim of the research was to conduct cross-sectional knowledge, attitude and practice (KAP) study of dengue among residents of tribal hostel in Bilaspur, Chhattisgarh (C.G).\u0000Methods: A community-based cross-sectional study was conducted among 150 students residing at a tribal hostel of Bilaspur.\u0000Results: The study showed that 95% of the participants had previously heard about dengue. Only 34.3% of the respondents were aware that dengue is a contagious disease, and only 48.6% knew that the disease is caused by the bite of mosquito. Almost 52% were aware of the exact source of disease transmission.\u0000Conclusions: When it came to basic knowledge about dengue, the majority of the respondents answered positively. However, there were large lacunae present within the specific knowledge of dengue such as, whether dengue is contagious, or about the biting and breeding time and site, respectively, of the mosquito.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"27 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prescribing patterns in patients with chronic liver and kidney disease in a tertiary care hospital","authors":"Pratichhya Mathema, Dinesh R. Neupane, Safal K. Shrestha","doi":"10.18203/2320-6012.ijrms20240325","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240325","url":null,"abstract":"Background: Liver diseases are major cause of mortality and morbidity worldwide. It is the 12th leading cause of death liver diseases can be classified as acute if the onset of symptom does not exceed six months or chronic if symptoms persist beyond this period. According to the recently available World Health Organization. The aim of study is to facilitate rational use of medicines.\u0000Methods: This study is a prospective, observational, single center study which include patients aged ≥18 years, diagnosis of liver diseases with or without co-morbidities and is conducted at out-patient of Medicine department, Rajindra Medical College and Hospital, Patiala.\u0000Results: In this study, total of 97 prescriptions of patients with liver disease were analyzed. Out of 97 patients, the majority of patients were male. In ALD, males were 32 (78%) whereas female were 9 (22%) while in CLD males were 47 (84%) and females were 9 (16%).While observing the LFT profile of patients with ALD common tests were observed which includes total bilirubin (1.82±2.42), SGOT (96.81±117.49) and SGPT (94.78±142.94) and in patients with CLD common tests were observed which includes total bilirubin (2.50±3.63), SGOT (67.50±43.04), SGPT (47.10±33.12), blood urea (46.92±24.14) and alkaline phosphatase (147.02±63.14).\u0000Conclusions: The study interprets the prescribing pattern of drugs used in patients with ALD and CLD and observed that vitamins and minerals and antibiotics were the most prescribed in order to avoid further complications followed by hepatoprotective agents, antiulcer drugs, antihypertensives and laxatives.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"220 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139839513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prescribing patterns in patients with chronic liver and kidney disease in a tertiary care hospital","authors":"Pratichhya Mathema, Dinesh R. Neupane, Safal K. Shrestha","doi":"10.18203/2320-6012.ijrms20240325","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240325","url":null,"abstract":"Background: Liver diseases are major cause of mortality and morbidity worldwide. It is the 12th leading cause of death liver diseases can be classified as acute if the onset of symptom does not exceed six months or chronic if symptoms persist beyond this period. According to the recently available World Health Organization. The aim of study is to facilitate rational use of medicines.\u0000Methods: This study is a prospective, observational, single center study which include patients aged ≥18 years, diagnosis of liver diseases with or without co-morbidities and is conducted at out-patient of Medicine department, Rajindra Medical College and Hospital, Patiala.\u0000Results: In this study, total of 97 prescriptions of patients with liver disease were analyzed. Out of 97 patients, the majority of patients were male. In ALD, males were 32 (78%) whereas female were 9 (22%) while in CLD males were 47 (84%) and females were 9 (16%).While observing the LFT profile of patients with ALD common tests were observed which includes total bilirubin (1.82±2.42), SGOT (96.81±117.49) and SGPT (94.78±142.94) and in patients with CLD common tests were observed which includes total bilirubin (2.50±3.63), SGOT (67.50±43.04), SGPT (47.10±33.12), blood urea (46.92±24.14) and alkaline phosphatase (147.02±63.14).\u0000Conclusions: The study interprets the prescribing pattern of drugs used in patients with ALD and CLD and observed that vitamins and minerals and antibiotics were the most prescribed in order to avoid further complications followed by hepatoprotective agents, antiulcer drugs, antihypertensives and laxatives.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"32 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139779509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitude and practice on dengue among residents of tribal hostel in Bilaspur: a cross-sectional study","authors":"Vivek Sharma, Nasarin Parveen, Darwin Deissuza","doi":"10.18203/2320-6012.ijrms20240324","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240324","url":null,"abstract":"Background: In the present era, vector-born disease accounts for 17% of the estimated global burden of all infectious diseases. One such deadly vector-borne disease is dengue. Dengue, dengue hemorrhagic fever, and dengue shock syndrome are major international public health concerns; 2.5 billion people live in high-risk dengue areas with 50 million dengue infections worldwide annually. Aim of the research was to conduct cross-sectional knowledge, attitude and practice (KAP) study of dengue among residents of tribal hostel in Bilaspur, Chhattisgarh (C.G).\u0000Methods: A community-based cross-sectional study was conducted among 150 students residing at a tribal hostel of Bilaspur.\u0000Results: The study showed that 95% of the participants had previously heard about dengue. Only 34.3% of the respondents were aware that dengue is a contagious disease, and only 48.6% knew that the disease is caused by the bite of mosquito. Almost 52% were aware of the exact source of disease transmission.\u0000Conclusions: When it came to basic knowledge about dengue, the majority of the respondents answered positively. However, there were large lacunae present within the specific knowledge of dengue such as, whether dengue is contagious, or about the biting and breeding time and site, respectively, of the mosquito.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"74 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139836633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}