结核病引起的肠梗阻:揭开无声风险的面纱

Chandrakala Kumari, N. P. Narain
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摘要

背景:肠结核(TB)仍然是一项全球性的健康挑战,尤其是在结核病高发地区。肠结核不同于肺结核,其表现涉及胃肠道,往往导致肠梗阻。该研究探讨了这种疾病的隐匿性,强调了及时诊断和干预的紧迫性。认识到结核病对不同器官的多方面影响,本研究探讨了肠结核的病理生理学、临床表现和诊断的复杂性:本研究在印度比哈尔邦巴特那市的那兰达医学院和医院进行,是一项为期三年的回顾性研究,重点关注 127 名因肺结核导致肠梗阻的患者。纳入标准优先考虑结核病组织病理学确诊,以确保队列的准确性。研究采用了初步检查方法,包括血液检查、胸部 X 光检查、腹部 X 光检查、超声波检查、痰液检查、Mantoux 试验和全腹部 CECT 检查。对临床表现进行了系统分析,并根据表现方式制定了有针对性的管理方案:从人口统计学角度看,127 个病例的病因是结核病,性别分布均衡,21-30 岁年龄组发病率最高。患者表现各异,以急性症状为主。常见症状包括腹痛、呕吐、便秘和腹胀。61.1%的病例必须在24小时内进行手术治疗。术中发现肠系膜增厚、淋巴结肿大和粘连。粘连溶解是主要的手术方法。术后并发症主要是伤口感染,但对死亡率的影响有限:这项研究揭示了肺结核是导致肠梗阻的重要因素,并强调了早期诊断所面临的挑战。粘连溶解是一种关键的手术方法,强调了手术灵活性的必要性。术后并发症虽然显著,但对死亡率的影响微乎其微。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intestinal obstruction caused by tuberculosis: unmasking a silent risk
Background: Intestinal tuberculosis (TB) remains a global health challenge, especially in regions with a high TB prevalence. This manifestation, distinct from pulmonary TB, involves the gastrointestinal tract, often leading to intestinal obstruction. The study addresses the insidious nature of the disease, emphasizing the urgency for timely diagnosis and intervention. Recognizing the multifaceted impact of TB on various organs, the study explores the pathophysiology, clinical presentation, and diagnostic complexities of intestinal TB. Methods: This study was conducted at Nalanda medical college and hospital in Patna, Bihar, India, the retrospective study spans three years focusing on 127 patients with intestinal obstruction due to TB. Inclusion criteria prioritized histopathological confirmation of TB, ensuring cohort accuracy. The study employed preliminary investigations, including hemogram, chest X-ray, abdominal X-ray, ultrasonogram, sputum examination, and Mantoux test and CECT whole abdomen. Clinical presentations were systematically analyzed, guiding tailored management protocols based on the mode of presentation. Results: Demographically, the study identified TB as the cause in 127 cases, with a balanced gender distribution and a peak incidence in the 21-30 years age group. Presentations varied, predominantly with acute symptoms. Common complaints included abdominal pain, vomiting, constipation, and distension. Surgical intervention within 24 hours was crucial in 61.1% of cases. Intraoperatively, findings comprised mesenteric thickening, lymph nodal enlargement, and adhesions. Adhesionolysis was the primary procedure. Postoperative complications, mainly wound infections, were noted but had a limited impact on mortality. Conclusions: This study reveals TB as a significant contributor to intestinal obstruction, emphasizing challenges in early diagnosis. Adhesionolysis emerges as a key operative procedure, underscoring the need for surgical flexibility. Postoperative complications, while notable, have minimal impact on mortality.
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