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International Journal of Polymeric Materials and Polymeric Biomaterials最新文献

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Reactive Flash Nanoprecipitation: Expanding the Landscape of Nanoparticle Fabrication for Biomedical Applications. 反应性闪蒸纳米沉淀：扩展生物医学应用的纳米颗粒制造领域。
IF 3.2 4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2026-07-19 DOI: 10.1080/00914037.2026.2702930
Huari Kou, Lin Qi, Da Huang, Hu Yang
{"title":"Reactive Flash Nanoprecipitation: Expanding the Landscape of Nanoparticle Fabrication for Biomedical Applications.","authors":"Huari Kou, Lin Qi, Da Huang, Hu Yang","doi":"10.1080/00914037.2026.2702930","DOIUrl":"10.1080/00914037.2026.2702930","url":null,"abstract":"<p><p>Scaling up nanoparticle production remains a major challenge that limits the translation of nanotechnology. Flash nanoprecipitation (FNP), first introduced by Prud'homme in 2003, offers a promising approach to bridge laboratory-scale synthesis and industrial manufacturing. Building on his pioneering studies, FNP has been applied not only to fabricate nanoparticles encapsulating hydrophobic drugs but also to generate particles with increasingly complex architectures. In this perspective, recent developments in the field are highlighted, and an emerging direction is proposed: reactive FNP (rFNP). In-situ crosslinking and possibly other chemical reactions are integrated directly into the flash nanoprecipitation process. It demonstrates that selected chemical reactions, including click chemistry and precipitation reactions, can be incorporated directly into FNP to create nanoparticles with enhanced chemical stability, improved physical properties, and broader functional capabilities. While this review is centered on new opportunities for applying rFNP-based strategies in biomedical and pharmaceutical applications, it also underscores broader possibilities for nanoparticle preparation and functionalization across a wide range of other fields.</p>","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a biofunctional conductive neural scaffold based on chitosan, polycaprolactone, carvacrol and polyaniline 壳聚糖、聚己内酯、香芹酚和聚苯胺基生物功能导电神经支架的研制
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-11-15 DOI: 10.1080/00914037.2025.2585530
Elif Özalp, Büşra Oktay, Fatih Çiftçi, Azime Erarslan, Esma Ahlatcıoğlu Özerol
{"title":"Development of a biofunctional conductive neural scaffold based on chitosan, polycaprolactone, carvacrol and polyaniline","authors":"Elif Özalp, Büşra Oktay, Fatih Çiftçi, Azime Erarslan, Esma Ahlatcıoğlu Özerol","doi":"10.1080/00914037.2025.2585530","DOIUrl":"https://doi.org/10.1080/00914037.2025.2585530","url":null,"abstract":"Damage in neural tissues poses a significant challenge in regenerative medicine, requiring scaffolds that support both biological and electrical functions. Conductive biomaterials offer promising solutions by promoting neural repair and integration. However, the development of multifunctional scaffolds that simultaneously provide electrical conductivity, antioxidant activity, mechanical strength, and biocompatibility remains limited. This study aims to develop and characterize a biofunctional conductive neural tissue scaffold. The incorporation of polyaniline (PANI) enhanced electrical conductivity, while the addition of carvacrol (CRV) improved antioxidant activity and biological function but slightly reduced conductivity in the layered structure. In the second-layer scaffold model, cell viability reached 140% thanks to carvacrol. The electrical conductivity of the chitosan/polyaniline film was measured as 1.429 x10−2 S/m using the four-point probe method. A second layer of polycaprolactone/carvacrol was formed onto the chitosan/polyaniline conductive film using electrospinning, and the conductivity was measured as 1.052 x10−3 S/m. The values obtained for both conductive scaffolds have been shown to provide good electrical conductivity in conductive tissue scaffolds used in neural tissue engineering studies. Polycaprolactone (PCL) contributed to mechanical strength, and chitosan (CHI) improved biocompatibility. The combination of these components resulted in a scaffold with suitable properties for neural tissue repair, particularly under neurodegenerative conditions.","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"75 5","pages":"600-610"},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147914578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyglycerols-based hydrogels for biomedical applications: a comprehensive review 生物医学应用的聚甘油基水凝胶：综合综述
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-08-21 DOI: 10.1080/00914037.2025.2546870
Soheila Zare, Hadi Hosseinpour, Mohammad Foad Abazari, Tayebeh Noori, Rana Jahanban‐Esfahlan, Mehdi Jaymand
{"title":"Polyglycerols-based hydrogels for biomedical applications: a comprehensive review","authors":"Soheila Zare, Hadi Hosseinpour, Mohammad Foad Abazari, Tayebeh Noori, Rana Jahanban‐Esfahlan, Mehdi Jaymand","doi":"10.1080/00914037.2025.2546870","DOIUrl":"https://doi.org/10.1080/00914037.2025.2546870","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"75 3","pages":"325-345"},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147918377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Synthesis and structural characterization of pyrroloquinoline quinone grafted carboxymethyl chitosan copolymer with neuroprotective potential 具有神经保护作用的吡咯喹啉醌接枝羧甲基壳聚糖共聚物的合成及结构表征
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-07-24 DOI: 10.1080/00914037.2025.2537951
Shengnan Zheng, Chuzhou Wen, Jiaxue Tang, Changkai Sun, Fengtao Wang, Shui Guan
{"title":"Synthesis and structural characterization of pyrroloquinoline quinone grafted carboxymethyl chitosan copolymer with neuroprotective potential","authors":"Shengnan Zheng, Chuzhou Wen, Jiaxue Tang, Changkai Sun, Fengtao Wang, Shui Guan","doi":"10.1080/00914037.2025.2537951","DOIUrl":"https://doi.org/10.1080/00914037.2025.2537951","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"75 3","pages":"239-250"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147881275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colon-targeted drug delivery systems through electrospun core–shell nanofiber loaded with camptothecin for the treatment of colorectal cancer 电子纺核壳纳米纤维载喜树碱结肠靶向药物递送系统治疗结直肠癌
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-06-11 DOI: 10.1080/00914037.2025.2477159
Yanzhi Zhao, Xueqian Ma, Haitang Xu, Long Han, Mengjun Zou, Qi Wen, Juying Zhou
{"title":"Colon-targeted drug delivery systems through electrospun core–shell nanofiber loaded with camptothecin for the treatment of colorectal cancer","authors":"Yanzhi Zhao, Xueqian Ma, Haitang Xu, Long Han, Mengjun Zou, Qi Wen, Juying Zhou","doi":"10.1080/00914037.2025.2477159","DOIUrl":"https://doi.org/10.1080/00914037.2025.2477159","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"74 17","pages":"1586-1595"},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147334239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Preparation and in vitro evaluation of bergapten-loaded liposomes 载bergapten脂质体的制备及体外评价
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-04-16 DOI: 10.1080/00914037.2025.2486986
Yajing Wu, Xuelian Wang, Xiaohong Yang, Ping Liu, Miao Pan, Yingyan Shen, Xuemei Lan, Lingzhi Lu, Yunhong Wang, Yuanfang Hou, Xiumei Ke, Rongping Yang
{"title":"Preparation and <i>in vitro</i> evaluation of bergapten-loaded liposomes","authors":"Yajing Wu, Xuelian Wang, Xiaohong Yang, Ping Liu, Miao Pan, Yingyan Shen, Xuemei Lan, Lingzhi Lu, Yunhong Wang, Yuanfang Hou, Xiumei Ke, Rongping Yang","doi":"10.1080/00914037.2025.2486986","DOIUrl":"https://doi.org/10.1080/00914037.2025.2486986","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"1 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147877672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-functional injectable nanofiber hydrogels with anti-inflammatory and osteogenic effects for bone regeneration 具有抗炎和成骨作用的双功能可注射纳米纤维水凝胶
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-03-24 DOI: 10.1080/00914037.2025.2481418
Hongtao Li, Hanping He, Wenhui Chen, Yuehan Dong, Xiangjie Wu, ZY Xia, Yang Zhou, Lin Yang, Huan Deng, Zhijun Huang, Wenjin Xu, Peihu Xu, Haixing Xu
{"title":"Dual-functional injectable nanofiber hydrogels with anti-inflammatory and osteogenic effects for bone regeneration","authors":"Hongtao Li, Hanping He, Wenhui Chen, Yuehan Dong, Xiangjie Wu, ZY Xia, Yang Zhou, Lin Yang, Huan Deng, Zhijun Huang, Wenjin Xu, Peihu Xu, Haixing Xu","doi":"10.1080/00914037.2025.2481418","DOIUrl":"https://doi.org/10.1080/00914037.2025.2481418","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"74 18","pages":"1640-1656"},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation and characterization of photocrosslinked bletilla striata polysaccharide/hyaluronic acid injectable hydrogels 光交联白芨多糖/透明质酸注射水凝胶的制备与表征
4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2025-03-24 DOI: 10.1080/00914037.2025.2481423
Yilong Wei, Yanan Jiang, Doudou Ma, Li Luo, Jiandong Ma, Xiaoliang Zhao, Yonggang Wang, Jing Zhang, Cunjin Wang, Weijie Zhang
{"title":"Preparation and characterization of photocrosslinked bletilla striata polysaccharide/hyaluronic acid injectable hydrogels","authors":"Yilong Wei, Yanan Jiang, Doudou Ma, Li Luo, Jiandong Ma, Xiaoliang Zhao, Yonggang Wang, Jing Zhang, Cunjin Wang, Weijie Zhang","doi":"10.1080/00914037.2025.2481423","DOIUrl":"https://doi.org/10.1080/00914037.2025.2481423","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"74 18","pages":"1657-1671"},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147886745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cinnamaldehyde-poly (lactic acid)/gelatin nanofibers exhibiting antibacterial and antibiofilm activity 具有抗菌和抗生物膜活性的肉桂醛-聚（乳酸）/明胶纳米纤维
IF 3.2 4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2024-08-29 DOI: 10.1080/00914037.2024.2395879
Zeynep Akpınar, Seyhan Ulusoy, Mert Akgün, Ayhan Oral, Salih Can Suner
{"title":"Cinnamaldehyde-poly (lactic acid)/gelatin nanofibers exhibiting antibacterial and antibiofilm activity","authors":"Zeynep Akpınar, Seyhan Ulusoy, Mert Akgün, Ayhan Oral, Salih Can Suner","doi":"10.1080/00914037.2024.2395879","DOIUrl":"https://doi.org/10.1080/00914037.2024.2395879","url":null,"abstract":"Bacterial infections and biofilms are known to impede the wound-healing process. Naturally derived compounds from plants hold promise in inhibiting or preventing bacterial biofilms, with cinnamalde...","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"43 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142256766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microencapsulation of turmeric oleoresin: complex coacervation and crosslinking strategies for improving encapsulation efficiency and stability in gastrointestinal simulated fluids 姜黄精的微胶囊化：提高胶囊化效率和胃肠道模拟液稳定性的复合共凝胶和交联策略
IF 3.2 4区 医学
International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2024-08-29 DOI: 10.1080/00914037.2024.2393876
Hugo Espinosa-Andrews, Karina Enriquez, Consuelo Lobato-Calleros
{"title":"Microencapsulation of turmeric oleoresin: complex coacervation and crosslinking strategies for improving encapsulation efficiency and stability in gastrointestinal simulated fluids","authors":"Hugo Espinosa-Andrews, Karina Enriquez, Consuelo Lobato-Calleros","doi":"10.1080/00914037.2024.2393876","DOIUrl":"https://doi.org/10.1080/00914037.2024.2393876","url":null,"abstract":"Turmeric oleoresin microcapsules were prepared by complex coacervation of gum arabic (GA) and chitosan (Ch) using genipin as a crosslinker. For this propose, the effect of pH and the biopolymer mas...","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"10 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142207067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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