International Journal of Phytomedicine最新文献_第7页

Antitesticular activities of different solvent fractions from hydro-methanol (2:3) extract of Cuminum cyminum in albino rat: A Comparative analysis 白化大鼠茴香水甲醇(2:3)提取物不同溶剂组分抗睾丸活性的比较分析

International Journal of Phytomedicine Pub Date : 2017-12-28 DOI: 10.5138/09750185.2131

B. P. Pakhira, Abhinandan Ghosh, Adrija Tripathy, D. Ghosh

{"title":"Antitesticular activities of different solvent fractions from hydro-methanol (2:3) extract of Cuminum cyminum in albino rat: A Comparative analysis","authors":"B. P. Pakhira, Abhinandan Ghosh, Adrija Tripathy, D. Ghosh","doi":"10.5138/09750185.2131","DOIUrl":"https://doi.org/10.5138/09750185.2131","url":null,"abstract":"Currently available contraceptives are associated with adverse effects. So, search on safer agents in this purpose is one of the priority areas of WHO. Our previous study showed a significant antifertility effect of hydro-methanol extract of Cuminum cyminum Linn (Umbelliferae) in male albino rat. The main objective of this work isto search outthe potentfraction of hydro-methanol extract of seed of Cuminum cyminum in adult male albino rat for the development of herbal male contraceptive to reduce the bio-burden of phytomolecules. The n-hexane, chloroform, ethyl acetate, and n-butanol fractions of the hydro-methanol (2:3) extract of seed of Cuminum cyminum were administrated orally to male rat. Results showed the maximum antitesticular activity of chloroform fraction (CH-Fr) than other fractions included here. Treatment with CH-Fr fraction resulted a significant inhibition in spermiological parameters, activities of testicular androgenic key enzymes and antioxidative enzymes, levels of serum testosterone and seminal vesicular fructose, number of different generations of germ cells at stage VII of spermatogenic cell cycle and seminiferous tubular diameter (STD) along with significant increase in the level of testicular cholesterol in respect to the control. Significant upward and downward expression in Bax and Bcl-2 gene of male germ cells were indicated which focussed the sperm apoptotic enhancer activities of the fraction. The findings indicated that among the said four different fractions, the chloroform fraction of the hydro-methanol extract of the seed of Cuminum cyminum had most effective antitesticular activity.","PeriodicalId":14199,"journal":{"name":"International Journal of Phytomedicine","volume":"27 1","pages":"605-614"},"PeriodicalIF":0.0,"publicationDate":"2017-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77225875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of free radical scavenging activity of leaf of Hypericum mysorense Heyne 金丝桃叶片自由基清除活性的评价

International Journal of Phytomedicine Pub Date : 2017-12-28 DOI: 10.5138/09750185.2137

Sornalakshmi, P. S. Tresina, K. Paulpriya, V. Mohan

引用次数: 0

Comparative phytochemical and antioxidant profile of crude seed powder, aqueous and methanolic seed extracts of Buchholzia coriacea 毛茛种子粗粉、水提物和甲醇提物的植物化学和抗氧化特性比较

International Journal of Phytomedicine Pub Date : 2017-12-28 DOI: 10.5138/09750185.2117

G. Ugwu, Joseph Effiong Eyo, Jude Ifeanyi Egbuji, C. S. Ezechukwu, K. N. Ibemenuga

{"title":"Comparative phytochemical and antioxidant profile of crude seed powder, aqueous and methanolic seed extracts of Buchholzia coriacea","authors":"G. Ugwu, Joseph Effiong Eyo, Jude Ifeanyi Egbuji, C. S. Ezechukwu, K. N. Ibemenuga","doi":"10.5138/09750185.2117","DOIUrl":"https://doi.org/10.5138/09750185.2117","url":null,"abstract":"The increasing discovery of more medicinal plants have triggered increased scientific screening of their bioactivity in order to provide data that will help physicians and patients make wise decision before using them. This study was designed to elucidate comparative phytochemical and antioxidant properties of crude seed powder, aqueous and methanolic seed extracts of Buchholzia coriacea. The results showed that crude seed powder had the highest alkaloid and phenol content of 3.98 ± 0.00% and 0.92 ± 0.00%, while aqueous extract had the least alkaloid and phenol content of 1.00 ± 0.00% and 0.12 ± 0.00% respectively. Methanolic extracts had the highest phytochemical components among the three extracts with flavonoids (12.03 ± 0.0), saponins (1.99 ± 0.01), terpenoids (2.00 ± 0.00), tannin (0.10 ± 0.00) and phytate (2.02 ± 0.01) compositions, while aqueous extracts had the highest hydrogen cyanide (0.30 ± 0.00) and glycoside (0.35 ± 0.00). Antioxidant (DPPH) activities of B. coriacea showed that aqueous extract and crude seed powder had inhibition concentration (IC 50 ) of 4.65 mg/ml while methanolic extract had IC 50 of 5.85 mg/ml. The result of the LD 50 of the extracts showed the each extracts was well tolerated at a dose of 5000 mg/kg, an indication of high safety profile. The study therefore clearly demonstrated that methanolic extracts of B. coriacea have antioxidant, antihypertensive, hypocholesterolmic and anticarcinogenic properties owing to the presence of high levels of phytochemical components than the aqueous and crude seed powder.","PeriodicalId":14199,"journal":{"name":"International Journal of Phytomedicine","volume":"16 1","pages":"558-565"},"PeriodicalIF":0.0,"publicationDate":"2017-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75181393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Triterpenoids with Cytotoxic Potential from the Leaves of Tridax procumbens L. 原楚梅叶中具有细胞毒性的三萜。

International Journal of Phytomedicine Pub Date : 2017-12-28 DOI: 10.5138/09750185.2109

Vaishali M. Rai, V. Pai, S. R. Duwal

引用次数: 0

Screening of some plant materials used in South-West Algerian traditional medicine for their antibacterial activity 阿尔及利亚西南部传统医药中一些植物材料抗菌活性的筛选

International Journal of Phytomedicine Pub Date : 2017-12-28 DOI: 10.5138/09750185.2161

Fatehi Naima, H. Benmehdi, A. Hocine, O. Nawal

{"title":"Screening of some plant materials used in South-West Algerian traditional medicine for their antibacterial activity","authors":"Fatehi Naima, H. Benmehdi, A. Hocine, O. Nawal","doi":"10.5138/09750185.2161","DOIUrl":"https://doi.org/10.5138/09750185.2161","url":null,"abstract":"The initial introduction of new medicinal agents into the health care system sometimes, requires information beyond that is recorded in libraries relying instead, on reports available through traditions and healers within a society. This paper explored the antibacterial activity of aqueous and hydromethanolic extracts of nine folkloric medicinal plant from Bechar region (southwest Algeria) namely: A. nardus, A. schoenanthus, G. vulgaris, two species of H. scoparia green & red, P. laevigata, R. tripartita, T. gallica and T. nudatum , frequently used in the local traditional medicine. The antibacterial activity of different extracts were evaluated by using disc diffusion method agar and antibiotics susceptibility of ten selected microorganisms: seven reference strains, Bacillus cereus, Enterococcus faecalis, Staphylococcus aureus , Escherichia coli , Klebsiella pneumoniae, Pseudomonas aeruginosa , Salmonella typhi , and three clinically isolated strains, Escherichia coli (Urinary Tract Infection), Escherichia coli (Vaginal Infection) and Staphylococcus aureus (Skin Infection). The maximum antibacterial activity was recorded against the gram negative reference strains Pseudomonas aeruginosa and Escherichia coli with a maximum inhibition diameter of 15.6 ± 0.5 and 15.0 ± 1.4 mm respectively displayed by the aqueous extract of T. gallica, followed by the activity detected by the hydromethanolic extract of R. tripartita against the gram negative reference strain Pseudomonas aeruginosa (14.6±1.2 mm) and the aqueous and hydromethanolic extracts of R. tripartita against the gram negative reference strains Pseudomonas aeruginosa and Escherichia coli with a maximum inhibition diameter of 14.3 ± 2.0 and 14.3±0.5 mm, respectively. According to the present study, H. scoparia red, P. laevigata, R. tripartita, and T. gallica can be served as broad spectrum antibiotic and used as a potent source of natural antibacterial agents by replacing commercially available synthetic drug that may have a large number of side effects.","PeriodicalId":14199,"journal":{"name":"International Journal of Phytomedicine","volume":"9 1","pages":"619-627"},"PeriodicalIF":0.0,"publicationDate":"2017-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82164328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cordia macleodii Hook f. Thomson-A potential Medicinal Plant 一种潜在的药用植物

International Journal of Phytomedicine Pub Date : 2017-09-02 DOI: 10.5138/09750185.2105

Jagriti Chandrakar, A. Dixit

引用次数: 0

Chemical composition, antioxidant and antimicrobial activities of stem barks of Englerina gabonensis Engler and Sterculia tragacantha Lindl from Gabon 加蓬产加蓬栎(Englerina gabonensis Engler)和加蓬栎(Sterculia tragacantha Lindl)茎皮的化学成分及抗氧化和抗菌活性

International Journal of Phytomedicine Pub Date : 2017-09-02 DOI: 10.5138/09750185.2124

C. Obiang, R. Ngoua-Meye-Misso, Guy-Roger Ndong-Atome, J. Ondo, L. Obame-Engonga, E. Nsi-Emvo

{"title":"Chemical composition, antioxidant and antimicrobial activities of stem barks of Englerina gabonensis Engler and Sterculia tragacantha Lindl from Gabon","authors":"C. Obiang, R. Ngoua-Meye-Misso, Guy-Roger Ndong-Atome, J. Ondo, L. Obame-Engonga, E. Nsi-Emvo","doi":"10.5138/09750185.2124","DOIUrl":"https://doi.org/10.5138/09750185.2124","url":null,"abstract":"Aim of this work was to evaluate the phytochemical constituents, antioxidant and antimicrobial potential of water-acetone, water-ethanol and water extracts of Englerina gabonensis and Sterculia tragacantha .Presence of phenols was evaluated to estimate the effects of plants on microbial diseases. Water-acetone, water-ethanol and water extracts were examined for antioxidant activities. All plant extracts were tested against six reference strains, eleven clinical isolates and two fungal strains. Phenolic content were highest in the water-acetone and water-ethanol extracts from Englerinagabonensis in comparison with Sterculia tragacantha .The AAI (Antioxidant Activity Index)of water-acetone and water-ethanol extracts of Englerina gabunensis are superiors with 2. Plant extracts of Sterculia tragacantha show weak antioxidant activity (AAI < 0.5).The aqueous extract of Englerina gabonensis has a bactericidal effect on Salmonella Spp . Water-ethanol extract is bactericidal on Bacillus cereus LMG 13569 BHI, Salmonella Spp and Neisseria meningitides. Water-acetone extract presents a bactericidal activity on Enterococcus faecalis 103907 CIP, Escherichi coli , Staphylococcus aureus , Acinetobacter baumannii and Neisseria meningitides. Our results suggest that Englerina gabonensis extracts contain greater antioxidant and antimicrobial properties than Sterculia tragacantha extracts.","PeriodicalId":14199,"journal":{"name":"International Journal of Phytomedicine","volume":"30 1","pages":"501-510"},"PeriodicalIF":0.0,"publicationDate":"2017-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76560772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Analgesic and acute inflammation properties of the aqueous extract of dried leaves of Paullinia Pinnata (Sapindaceae) Linn 山楂叶水提物的镇痛和急性炎症作用

International Journal of Phytomedicine Pub Date : 2017-09-02 DOI: 10.5138/09750185.2115

Dingom Aurelie Taylor Patience, Keugni Armand Brice, Bendegue Emebe Alexandrie Julia, D. Désiré, Kamtchouing Pierre, T. Dimo

{"title":"Analgesic and acute inflammation properties of the aqueous extract of dried leaves of Paullinia Pinnata (Sapindaceae) Linn","authors":"Dingom Aurelie Taylor Patience, Keugni Armand Brice, Bendegue Emebe Alexandrie Julia, D. Désiré, Kamtchouing Pierre, T. Dimo","doi":"10.5138/09750185.2115","DOIUrl":"https://doi.org/10.5138/09750185.2115","url":null,"abstract":"Inflammation is frequently associated with pain. Plants continue to be major resources for therapeutic compounds against various diseases including inflammation and pain. P aullinia Pinnata is used to treat several diseases, including rheumatism and abdominal pain. This study was undertaken to assess the analgesic and anti-inflammatory effects of P aullinia Pinnata. The analgesic activity was evaluated by using behaviour pain model in mice. The anti-inflammatory activity was carried out by using carrageenan, dextran, histamine and serotonin induced inflammation in rat. The extract was administered orally at a dose of 200 and 400 mg/kg. The results showed that the extract significantly (P< 0.001) reduced the number of writhing induced by the acid acetic. The aqueous extract reduced significantly (P< 0.001) the paw licking time in formalin model. The effect of the extract (200mg/kg) was significantly (P< 0.001) reduced in the presence of naloxone, during the inflammatory phase. In addition, the extract significantly (P< 0.05) increase latency time at all point time and all doses on nociception induced by hot plate. Concerning inflammation induced by carrageenan and dextran, the extract significantly (P< 0.001) inhibited oedema during the experimental time at the dose of 200 mg/kg. The results suggested that Paullinia pinnata aqueous extract possess analgesic activities which may interfere in both peripheral and central pathway. The anti-inflammatory activities may be mediated by either inhibiting or by blocking the release of vasoactive substances like histamine, serotonin, kinins and prostaglandins. These results justify the traditional use of the plant in the treatment of pain and inflammation.","PeriodicalId":14199,"journal":{"name":"International Journal of Phytomedicine","volume":"76 1","pages":"490-497"},"PeriodicalIF":0.0,"publicationDate":"2017-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86182097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Pistacia integrrima Stewart ex Brandis: a less known high value medicinal plant 黄连木:一种鲜为人知的高价值药用植物

International Journal of Phytomedicine Pub Date : 2017-09-02 DOI: 10.5138/09750185.2037

B. Sharma, Sheezan Rasool, S. Pant

引用次数: 0

Evaluation of chemical profile and antioxidant potential of Trichodesma indicum (L.) R.Br. indicum (L.)木霉(Trichodesma indicum)的化学特性及抗氧化潜力评价R.Br。

International Journal of Phytomedicine Pub Date : 2017-09-02 DOI: 10.5138/09750185.2012

Mahendra S. Khyade, Subhash N Varpe, Anup D. Padwal

引用次数: 6