International journal of MS care最新文献

{"title":"Aerobic Exercise Training and Depressive Symptoms in People With Multiple Sclerosis: Brief Report on Default-Mode Network Resting-State Functional Connectivity.","authors":"Olesya Iosipchuk, Glenn R Wylie, Robert W Motl, Brian M Sandroff","doi":"10.7224/1537-2073.2024-003","DOIUrl":"10.7224/1537-2073.2024-003","url":null,"abstract":"<p><strong>Background: </strong>We sought to examine a potential neural mechanism of reduced depressive symptoms in response to aerobic treadmill walking exercise training in people with multiple sclerosis (MS). This includes a secondary analysis of depressive symptom and MRI data from an original randomized controlled trial (RCT) on exercise effects on learning and memory impairment in people with MS.</p><p><strong>Methods: </strong>Ten fully ambulatory people with MS were randomly assigned into either a 12-week aerobic treadmill walking condition or active control condition (ie, stretching and range-of-motion activities). All participants completed the Hospital Anxiety and Depression Scale for measurement of depressive symptoms as well as a resting-state functional MRI (fMRI) before and after the 12-week study period.</p><p><strong>Results: </strong>There were no between-condition differences in depressive symptoms at baseline. Participants who were randomly assigned to the intervention condition demonstrated reductions in depressive symptoms compared with minimal changes for those who underwent the control condition. This corresponded with significant changes in resting-state functional connectivity within the default-mode network (DMN).</p><p><strong>Conclusions: </strong>The overall pattern of results suggests that resting-state functional connectivity within the DMN may represent a potential neural mechanism underlying the beneficial effects of exercise on depressive symptoms in people with MS. Such results warrant future consideration in the design and conduct of future RCTs that aim to treat MS-related depression with aerobic exercise training in people with MS who have been prescreened for clinical depression.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"27 Q1","pages":"34-41"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic and Clinical Determinants of the Quality of Life of Moroccan People With Multiple Sclerosis.","authors":"Ilham Raji, Hind Bourkhime, Mohammed El Amine Ragala, Fedwa Nejjar, Mohammed Faouzi Belahsen","doi":"10.7224/1537-2073.2024-036","DOIUrl":"10.7224/1537-2073.2024-036","url":null,"abstract":"<p><strong>Background: </strong>The quality of life (QOL) of people with multiple sclerosis (MS) is considerably poorer than the QOL of people with other chronic diseases. QOL management should not be restricted to only clinical aspects but also factors modifying QOL. The aim of this study was to identify the sociodemographic and clinical determinants of QOL in people with MS.</p><p><strong>Methods: </strong>A cross-sectional study conducted from 2022 to 2023 included 200 participants aged 18 and over recruited from the Hassan II University Medical Hospital in Fez, Morocco. QOL assessment was performed using the Arabic version of the Multiple Sclerosis Quality of Life-54 (MSQOL-54) questionnaire. Univariate analysis using Student <i>t</i> test, analysis of variance, and Pearson correlation was performed, followed by multiple linear regression analysis to determine the main factors associated with QOL.</p><p><strong>Results: </strong>QOL was impaired in the physical health (PH) (48.51±22.08) and mental health (MH) (48.69±17.18) components of the MSQOL-54. Male sex, unemployment, and high scores on the Expanded Disability Status Scale (EDSS) were factors significantly associated with lower scores on both the PH and MH components. In contrast, later age at MS diagnosis and older age were significantly associated with worse PH and MH, respectively. EDSS score was a strong predictor of QOL (PH: β = -34.983; 95% CI, -39.64 to -30.31; MH: β = -23.383; 95% CI, -27.62 to -19.14).</p><p><strong>Conclusions: </strong>The results highlight the importance of sociodemographic and clinical determinants of QOL. Clinicians need to integrate a biopsychosocial approach into therapeutic education programs, considering the risk factors and specific needs of people with MS to optimize their QOL.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"27 Q1","pages":"25-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resilience Among Caregivers of People With Multiple Sclerosis: Exploring the Influence of Personality Traits, Coping, and Caregiver Burden.","authors":"Katelyn S Kavak, Dejan Jakimovski, Svetlana P Eckert, Kara Patrick, Samantha P Koury, Ralph H B Benedict, Susan A Green, Bianca Weinstock-Guttman","doi":"10.7224/1537-2073.2024-004","DOIUrl":"https://doi.org/10.7224/1537-2073.2024-004","url":null,"abstract":"<p><strong>Background: </strong>Resilience has been recognized as a vital protective factor in coping with stress and adversity. Multiple sclerosis (MS) caregiving is a complex and demanding role, often characterized by challenges.</p><p><strong>Methods: </strong>Caregivers of people with MS were recruited through health care professionals affiliated with the Jacobs MS Center for Treatment and Research in Buffalo, New York. Resilience was assessed by the Connor-Davidson Resilience Scale (CD-RISC-25) and the Health-Resilience-Stress Questionnaire (HRSQ). We examined the influence of personality traits (NEO Five-Factor Inventory-3), coping strategies (Brief Coping Orientation to Problems Experienced Inventory), quality of life (Adult Carer Quality of Life Questionnaire), and caregiver burden (Zarit Burden Interview) on resilience.</p><p><strong>Results: </strong>In our study of 98 caregivers (70.4% men; average age, 60 years), 91.8% were partners of people with MS. Out of a maximum score of 100, CD-RISC-25 scores were an average (SD) of 75.5 (14.4) and HRSQ scores were an average of 74.8 (12.9). Quality of life was positively associated with both resilience measures (<i>r</i> = 0.60 for CD-RISC-25; <i>r</i> = 0.70 for HRSQ), whereas higher resilience was linked to lower caregiver burden (<i>r</i> = -0.40 for CD-RISC-25; <i>r</i> = -0.49 for HRSQ). CD-RISC-25 showed higher resilience negatively correlated with neuroticism (<i>r</i> = -0.65) and positively with extroversion (<i>r</i> = 0.57) and conscientiousness (<i>r</i> = 0.59). HRSQ also showed strong negative correlation with neuroticism (<i>r</i> = -0.76) and positive correlations with extroversion (<i>r</i> = 0.60), conscientiousness (<i>r</i> = 0.53), and agreeableness (<i>r = 0.24</i>).</p><p><strong>Conclusions: </strong>Caregivers for people with MS showed relatively high resilience levels, positively correlating with quality of life and reduced caregiver burden. Furthermore, resilience correlated inversely with neuroticism and positively with extroversion and conscientiousness. Future research should target personalized interventions, particularly for caregivers with low resilience.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"27 Q1","pages":"15-24"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Gender Ideal Adherence on Carer Burden and Help-Seeking in Male Carers of People With Multiple Sclerosis.","authors":"Damien Appleton, Noelle Robertson, Rosie Lesley","doi":"10.7224/1537-2073.2023-073","DOIUrl":"10.7224/1537-2073.2023-073","url":null,"abstract":"<p><strong>Background: </strong>Multiple sclerosis is a chronic neurological disease that is commonly diagnosed in middle age and disproportionately affects women. Consequently, middle-aged men (as partners and husbands) are often the caregivers, a unique group in comparison with carers for people with other long-term neurological conditions, who are predominately women. Previous research has indicated that male carers respond differently from their female counterparts in terms of carer burden. Authors of gender role construct literature have reported that gender role conflict and gender role flexibility have an influence on men's attitudes about seeking help and support. The aim of this study was to investigate whether gender role conflict and gender role flexibility have an effect on help-seeking attitudes and carer burden within this unique group of carers.</p><p><strong>Methods: </strong>Data were collected from an international sample of 68 participants, using results from online and paper surveys, and were primarily analyzed using hierarchical regression analysis.</p><p><strong>Results: </strong>Results indicated that gender role conflict and gender role flexibility explained a significant variance in burden but were not significantly associated with attitudes toward help-seeking. Rather, appearance of coping was posited as a potential variable mediating the relationship between gender role conflict and help-seeking attitudes.</p><p><strong>Conclusions: </strong>These findings indicate how gender role constructs affect carer coping, suggesting that support for male carers may require tailored interventions. Appearance of coping is highlighted as a variable that requires further investigation. Further, a direction for psychoeducational interventions applicable to other groups of male carers is suggested.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"27 Q1","pages":"8-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PANORAMA: A 2021 Clinician Survey of Treatment Approaches for People With New Diagnoses of Relapsing-Remitting Multiple Sclerosis in the United Kingdom.","authors":"Nikos Evangelou, Miriam Mattoscio, Mhairi Coutts, Manoharan Andiappan, Teresa Sawtell, Katherine Rhys","doi":"10.7224/1537-2073.2023-079","DOIUrl":"https://doi.org/10.7224/1537-2073.2023-079","url":null,"abstract":"<p><strong>Background: </strong>The PANORAMA survey aimed to assess current treatment practice for individuals with new diagnoses of relapsing-remitting multiple sclerosis (RRMS) in the United Kingdom and to explore variations in treatment approaches with an emphasis on escalation vs early high-efficacy treatment (HET) and treatment goals.</p><p><strong>Methods: </strong>Health care professionals (HCPs) from the UK treating patients with RRMS took part in interviews facilitated by a structured questionnaire. Data were analyzed descriptively using quantitative or qualitative methods, as appropriate.</p><p><strong>Results: </strong>Thirty-eight HCPs from 38 UK centers took part in the survey, including 20 MS consultants and 13 MS specialist nurses. Seventy-four percent (n = 28 of 38) of HCPs strongly agreed and 24% (9 of 38) agreed that early treatment is essential for better outcomes. HCPs reported that they currently treat a mean (SD) of 58.3% (20.8%) and 42.1% (21.8%) of patients with new diagnoses of RRMS with early HET or escalation approaches, respectively. Thirty-four percent (13 of 38) of HCPs reported a discrepancy between current treatment approach and the approach they would like to take, which would be 66.2% favoring early HET and 33.8% favoring escalation approaches. The factors influencing the choice of treatment approach were overall patient health profile (45%, 17 of 38) and patient choice (39%, 15 of 38). The most important treatment goals were to reduce relapses (63%, 24 of 38), delay disability progression (58%, 22 of 38), and maintain quality of life (50%, 19 of 38).</p><p><strong>Conclusions: </strong>The survey highlights variation among HCPs in the UK in current vs ideal use of escalation or early HET approaches and factors influencing choice of treatment approach.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"27 Q1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142948358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Sclerosis Fatigue Self-Management: Strategies and Influencing Factors 5 Years After a Multimodal Intervention.","authors":"ShienPei C Silverman, Bishan Yang, Felicia Mata-Greve, Nikita Sajeev, Sophie Samiee, Julia Norton, Cinda L Hugos","doi":"10.7224/1537-2073.2024-012","DOIUrl":"10.7224/1537-2073.2024-012","url":null,"abstract":"<p><strong>Background: </strong>Fatigue: Take Control (FTC) is a multimodal self-management program. Results of a previous clinical trial showed its effectiveness at improving fatigue related to multiple sclerosis (MS). The objectives of this study were to use the very long-term data from the FTC study to understand fatigue management strategies used 5 years after enrollment, identify facilitators and barriers to utilizing strategies, and explore the potential relationships between the strategy used and fatigue outcomes.</p><p><strong>Methods: </strong>This study adopted a cross-sectional survey design. A subset of the original FTC clinical trial participants was invited to complete the Modified Fatigue Impact Scale for fatigue severity measurement and a 17-item questionnaire about their fatigue management strategies 5 years after enrollment. Descriptive statistics and content analysis were used to analyze quantitative and qualitative data using the COM-B (capability, opportunity, motivation-behavior) model for behavior change as a framework.</p><p><strong>Results: </strong>Planning daily activities and prioritizing tasks were the fatigue management strategies most often reported. Facilitators to utilizing management strategies included access to enabling devices, paid professional help, companions, and maintaining a positive attitude. Barriers to implementing strategies included high cost, the presence of other health problems, and temperature sensitivity. Internal focused strategies showed a trend toward reducing fatigue impact when controlled for typology group assignment.</p><p><strong>Conclusions: </strong>Future work may focus on promoting low-cost strategies to help people with MS manage fatigue. Internal factors (eg, motivation) play an important role in influencing the application of MS fatigue self-management strategies. Future clinical trials with larger sample sizes that assess the applicability of the COM-B model are warranted.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"26 Q4","pages":"363-369"},"PeriodicalIF":0.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11667032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ballroom Dancing for People With Multiple Sclerosis: Perceptions of the Experience.","authors":"Linda B Piacentine, Alice F Yan, Alexander V Ng","doi":"10.7224/1537-2073.2023-061","DOIUrl":"10.7224/1537-2073.2023-061","url":null,"abstract":"<p><strong>Background: </strong>Multiple sclerosis (MS) encompasses various symptoms, including fatigue, pain, spasticity, motor dysfunction, postural instability, sexual and bladder dysfunction, and cognitive impairment. Despite the documented benefits of exercise for alleviating MS symptoms, adherence to physical activity guidelines often is low, resulting in sedentary lifestyles among people with MS. This qualitative study explores the experiences of individuals with MS who participated in a ballroom dance intervention.</p><p><strong>Methods: </strong>Thirteen community-dwelling individuals with MS participated in five 1-hour focus group sessions as part of a larger ballroom dance study. The Framework Method, utilizing NVivo qualitative analysis software, was applied to verbatim transcripts.</p><p><strong>Results: </strong>Four themes emerged. (1) Physical and psychological benefits: Ballroom dance improved perceived symptoms, including strength, endurance, coordination, and balance, as well as reduced fatigue and alleviated depression. (2) Positive social support leading to enjoyment/fun: Ballroom dance fostered positive support and served as an enjoyable activity, including for couples. (3) Improved confidence: The dance intervention instilled confidence in physical abilities and emotional well-being. (4) Physical and social facilitation of activity: Ballroom dancing facilitated activity because partners were able to assist when fatigue or balance issues occurred, and the intervention provided social acceptability.</p><p><strong>Conclusions: </strong>Recreational ballroom or social dance was well tolerated, and individuals with MS and researchers perceived it as beneficial as it led to positive physical and psychological changes. This partnered social dance intervention provided an emotionally and physically supportive environment, improved confidence, and facilitated activity. This study contributes to the understanding of the potential of recreational ballroom dancing to promote physical activity and well-being among people who are living with MS.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"26 Q4","pages":"355-362"},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability and Feasibility of the English Version of Elevida, a Self-Guided Online Fatigue Intervention for People With Multiple Sclerosis.","authors":"Jo Lane, Carmel Poyser, Yixuan Zhao, Robyn M Lucas, Björn Meyer, Christoph Heesen, Nicolas Cherbuin, Anne Brüstle, Susy Macqueen, Alice Richardson, Christian Lueck, Stefan M Gold","doi":"10.7224/1537-2073.2023-048","DOIUrl":"10.7224/1537-2073.2023-048","url":null,"abstract":"<p><strong>Background: </strong>Fatigue is common in multiple sclerosis (MS); it significantly impairs quality of life, and treatment options are limited. A randomized controlled trial of Elevida, a self-guided, online German fatigue intervention, showed significant benefit. We tested an English version of Elevida with people with MS in Australia.</p><p><strong>Methods: </strong>Participants were volunteers with MS who self-reported at least mild fatigue (≥ 43 on the Fatigue Scale for Motor and Cognitive Functions scale), some mobility (Expanded Disability Status Scale < 8), and no or mild cognitive difficulties (≤ 32 on the Multiple Sclerosis Neuropsychological Questionnaire). Participants completed the 9-week English Elevida program, commenting on and rating its acceptability. The Chalder Fatigue Scale was completed at baseline, end-of-program, and 2 months later. We undertook qualitative (thematic analysis) and quantitative (before/after differences, tested using paired <i>t</i> test) analyses.</p><p><strong>Results: </strong>Thirty-eight people with MS expressed an interest in the study; 26 were eligible; 20 began the study. Fifteen participants (75%) completed the program (mean [SD]: 58.9 [10.5] years of age, 67% women, 9 with relapsing MS, 6 with progressive MS). Over 90% of completing participants rated acceptability as good or very good, and approximately 70% found the program helpful. Three themes were identified: Positive or negative comments on program features, incorrect assumptions in program content, and personal experiences and reflections. Significant improvement (<i>P</i> < .01) in fatigue scores from baseline to program completion was maintained 2 months after program completion.</p><p><strong>Conclusions: </strong>Elevida was acceptable and effective for MS-related fatigue. Identified themes will guide further development of the program to satisfy users' sense of autonomy, competence, and relatedness.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"26 Q4","pages":"347-354"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11628539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consultative, Proactive Physical Therapy in Early Multiple Sclerosis.","authors":"Monica Hendricksen, Jake Boyer, Miriam Rafferty, Kristen Hohl, Edith L Graham, Roumen Balabanov, Dominique Kinnett-Hopkins","doi":"10.7224/1537-2073.2023-058","DOIUrl":"10.7224/1537-2073.2023-058","url":null,"abstract":"<p><strong>Background: </strong>Exercise training may be the most effective nonpharmacological symptomatic treatment for patients with multiple sclerosis (MS). Physical therapy (PT) can facilitate increased exercise through education, individualized exercise routines, goal setting, and supportive resources. However, traditional PT focuses on function restoration rather than proactive measures to prevent the advancement of morbidity. We present the application of a proactive physical therapy (PAPT) approach for individuals with MS.</p><p><strong>Methods: </strong>Neurologists referred patients to PT shortly after their MS diagnosis. Patients completed a shared decision-making-based evaluation of their current functional level, received education on exercise guidelines and goal-setting support, and established an exercise routine of an appropriate intensity. The patient and physical therapist communicated via email and telephone at 1 and 3 months. Assessments included physical function, Fatigue Severity Scale (FSS), and self-reported exercise at 6 months.</p><p><strong>Results: </strong>Three patients were referred directly to PAPT, and 1 transitioned from restorative PT. At 6 months, 3 patients reported regular aerobic, strengthening, and flexibility participation that met or exceeded established exercise recommendations. Two of 3 patients demonstrated clinically meaningful changes in functional outcome measures (eg, 10-meter Walk Test), a third patient remained stable in all functional outcome measures. Three patients reported significant improvements on the FSS at 6 months. The fourth patient did not complete the 6-month follow-up due to pregnancy complications but reported meeting guidelines at 3 months.</p><p><strong>Conclusions: </strong>A PAPT model of care is feasible and effective for patients who have been newly diagnosed with MS. With minimal PT visits, patients met established exercise guidelines and maintained or improved physical function.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"26 Q4","pages":"341-346"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Sclerosis Care in Latin America.","authors":"Valeria Rocha, Carlos Navas","doi":"10.7224/1537-2073.2024-085","DOIUrl":"10.7224/1537-2073.2024-085","url":null,"abstract":"<p><p>Latin America (LATAM) is a diverse region with more than 30 countries, each varying in cultural, economic, and social aspects. While multiple sclerosis (MS) care in LATAM has improved, there are still challenges to address. Epidemiologic studies have shown varying incidence rates of MS in the region, influenced by factors such as genetics, environmental conditions, and regional diversity. Scientific research on MS in LATAM has increased, with publications and consensus guidelines emerging. However, access to disease-modifying treatments remains a significant challenge in many countries due to affordability issues and limited availability of certain therapies. The region also faces obstacles in providing comprehensive MS care, including rehabilitation programs and diagnosis tools. There are collaborative efforts and initiatives in LATAM that are working toward overcoming these challenges and improving the overall quality of care for people with MS in the region.</p>","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"27 Theme","pages":"T7-T12"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}