International Journal of Herbal Medicine最新文献_第8页

A critical study on the acute oral toxicity of polyherbal formulation of Rosmarinus officinalis L. AND Withania somnifera L. in wistar Albino Rats 迷迭香与苦参复方对白化大鼠急性口服毒性的初步研究

International Journal of Herbal Medicine Pub Date : 2023-01-01 DOI: 10.22271/flora.2023.v11.i5b.897

Sowmya M, Kavya S, Kaveri KR, Shashank AS

{"title":"A critical study on the acute oral toxicity of polyherbal formulation of Rosmarinus officinalis L. AND Withania somnifera L. in wistar Albino Rats","authors":"Sowmya M, Kavya S, Kaveri KR, Shashank AS","doi":"10.22271/flora.2023.v11.i5b.897","DOIUrl":"https://doi.org/10.22271/flora.2023.v11.i5b.897","url":null,"abstract":"The present work was planned to evaluate minimum dose level and pathomorphological alterations in Wistar albino rats after administration of polyherbal formulation (Rosmarinus officinalis) and Ashwagandha (Withania somnifera) in 3:1 at 2 g/kg body weight accordance with the OECD guidelines 423. All the animals that were orally exposed to polyherbal formulation extracts were sacrificed after the Fourteen days trial. On gross examination, no specific lesions were observed in any of the organs, whereas microscopic examination revealed no changes. As there was zero mortality even after 14 days of exposure, it was concluded that the LD50 value was more than 2 g/kg body weight, and the above polyherbal formulation was considered non-toxic. The present study analyzed the minimum dose level of polyherbal formulation extract Rosmarinus officinalis and Withania somnifera and observed slight weight gain in all the experimental rats. Still, this study could not monitor any mortality or pathomorphological changes, so it can be concluded that the extracts of Rosmarinus officinalis and Withania somnifera are non-toxic or safe at 2 g/kg body weight. However, further studies with more experimental animals are warranted to ascertain polyherbal formulation's toxicity and safety level and use this to prepare new therapeutic agents in Ayurvedic medicine in the coming days.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135800868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytonutrient screening and evaluation of in-vitro antibacterial activity of onion and garlic peels: A comparative study with the prospects of waste to wealth 洋葱和大蒜皮的植物营养素筛选及体外抗菌活性评价:与废物转化为财富前景的比较研究

International Journal of Herbal Medicine Pub Date : 2022-12-01 DOI: 10.22271/flora.2022.v10.i6a.844

Moumita Saha, Shirsha Mukherjee, Shouvik Das, M. Chowdhury, Madhurima Das, Souhardya Sarkar, Sirshendu Chatterjee

{"title":"Phytonutrient screening and evaluation of in-vitro antibacterial activity of onion and garlic peels: A comparative study with the prospects of waste to wealth","authors":"Moumita Saha, Shirsha Mukherjee, Shouvik Das, M. Chowdhury, Madhurima Das, Souhardya Sarkar, Sirshendu Chatterjee","doi":"10.22271/flora.2022.v10.i6a.844","DOIUrl":"https://doi.org/10.22271/flora.2022.v10.i6a.844","url":null,"abstract":"The current world survey states that it has become a major issue of huge wastage of fruits and vegetables in our ecology and economy. The by-products of these vegetables can be a major source of nutrients with having potential phytochemical, antioxidant, and antimicrobial potential. Hence, the significance of our study is to do the comparative analysis of phytonutrients and in-vitro medicinal activity by using the discarded onion and garlic peels as sustainable resources. The results of the current study depict onion peel extracts contain highest concentration of polyphenols (174.95 ±20.42 mg GAE/g DW), flavonoids (49.97±1.77 mg QE/g DW), tannins (31.72±0.02 mg TAE/g DW), carbohydrates (30.39±1.30 mg GE/g DW), proteins (38.07±0.86 mg BSAE/g FW), whereas, garlic peel extracts contain highest concentration of antioxidants (37.54±1.05 mg AAE/g DW). Both the onion and garlic peel extract show the maximum zone of inhibition against E. coli . The outcome of the study comes up as a very innovative and beneficial way to cope up with the current life-style disorder and to reduce the risk of diseases.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91414570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The effect of the size of the red bajakah powder (Uncaria acida (Hunter) Roxb) on the quality of the tea produced 红巴迦粉(Uncaria acid (Hunter) Roxb)的大小对茶叶质量的影响

International Journal of Herbal Medicine Pub Date : 2022-12-01 DOI: 10.22271/flora.2022.v10.i6a.845

AnjeIina Nor Sari, S. Hamidah, Gusti Abdul Rahmat Thamrin, Y. Arifin

引用次数: 0

In-vivo assessment of the antiplasmodial efficacy of corchorus catharticus Blanco whole plant extract 白菖蒲全植物提取物体内抗疟原虫作用的研究

International Journal of Herbal Medicine Pub Date : 2022-11-01 DOI: 10.22271/flora.2022.v10.i6a.842

H. Zumbes, Aaron Kwapnoe, Hycinth Dapiya, E. Opara

引用次数: 0

Insights into phyto pharmaceutical studies of the under-utilized mangrove species of Lumnitzera racemosa wild: A review 未被充分利用的红树总形Lumnitzera racemosa野生种植物药物研究进展

International Journal of Herbal Medicine Pub Date : 2022-11-01 DOI: 10.22271/flora.2022.v10.i6a.839

K. Soumya, A. Srivani, G. K. Mohan

引用次数: 0

Phytochemical analysis and anticancer activity of Majidea zanguebarica Kirk Ex Oliv 麻瓜的植物化学分析及抗癌活性研究

International Journal of Herbal Medicine Pub Date : 2022-11-01 DOI: 10.22271/flora.2022.v10.i6a.841

A. Aksharadevi, P. Deepika, Dr. K. Chitra

引用次数: 0

Organoleptic test for herbal honey made from kelulut honey (Heterotrigona itama) and Sungkai’s leaf extract (Peronema canescens Jack) 用海露蜜(Heterotrigona itama)和松开叶提取物(Peronema canescens Jack)制成的草本蜂蜜的感官试验

International Journal of Herbal Medicine Pub Date : 2022-11-01 DOI: 10.22271/flora.2022.v10.i6a.838

A. Putri, S. Hamidah, Dan Lusyiani, Y. Arifin

引用次数: 0

Antioxidant activity of various extracts of Givotia moluccana (L.) Sreem 黄颡鱼不同提取物的抗氧化活性研究Sreem

International Journal of Herbal Medicine Pub Date : 2022-11-01 DOI: 10.22271/flora.2022.v10.i6a.843

A. Srivani, G. Mohan

引用次数: 0

Synergistic inhibition of the urinary tract pathogen Staphylococcus saprophyticus by curcumin and berberine 姜黄素和小檗碱对尿路病原菌腐生葡萄球菌的协同抑制

International Journal of Herbal Medicine Pub Date : 2022-05-01 DOI: 10.22271/flora.2022.v10.i3a.815

C. Deutch

引用次数: 0

Medicinal uses of a leafy cactus, Pereskia bleo, in Singapore: A survey on the users' knowledge and their perceptions 新加坡一种多叶仙人掌的药用:一项关于使用者知识和看法的调查

International Journal of Herbal Medicine Pub Date : 2022-01-01 DOI: 10.22271/flora.2022.v10.i1a.788

S. Zareisedehizadeh, Y. Siew, H. Wee, C. Tan, H. Koh

引用次数: 1