International Journal of Medical and Dental Sciences最新文献_第8页

The Effect of Supplementation of Standard Antibiotic Therapy with Oral Probiotics for Bacterial Vaginosis 标准抗生素加口服益生菌治疗细菌性阴道病的疗效观察

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18913

N. Grewal, A. Mahajan, J. K. Bajaj

{"title":"The Effect of Supplementation of Standard Antibiotic Therapy with Oral Probiotics for Bacterial Vaginosis","authors":"N. Grewal, A. Mahajan, J. K. Bajaj","doi":"10.18311/IJMDS/2018/18913","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18913","url":null,"abstract":"Background: Bacterial vaginosis is a common cause of vaginal infection worldwide in women of child bearing age. It can be asymptomatic or mild infection but can lead to many complications especially during pregnancy. Recurrence is also frequently seen in women suffering from bacterial vaginosis. This infection usually occurs when normal lactobacillus flora in vagina is disrupted and replaced by pathogens. Administration of probiotics will restore normal vaginal flora and maintain normal pH and it could prove to be a reliable alternative to antibiotics in future. Objective: To assess the effect of supplementation of standard antibiotic therapy with oral probiotics (Lactobacillus) for treatment of bacterial vaginosis. Material Methods: It was an open labeled prospective study in which 100 women diagnosed with bacterial vaginosis were randomly divided into two groups. Diagnosis was made using Amsel’s criteria and Nugent scoring was done. Group A was given Oral Metronidazole, 400 mg BD for 7 days along with oral probiotic tablet containing Lactobacillus rhamnosus BD for 6 weeks whereas Group B was administered Oral Metronidazole, 400 mg BD for 7 days. Patients were assessed at 7 days for symptomatic improvement and again at the end of 6 weeks using Nugent scores. Results obtained were then compared. Results: Out of all patients 2 patients in Group A and 5 patients in Group B could not complete the study. At the end of 7 days, there was improvement in symptoms ie decrease in itching, odour and discharge. There was a significant difference in mean Nugent score before and after treatment between group A and group B at the end of 6 weeks. Conclusion: This study concluded that improvement in patients taking probiotics along with standard antibiotic therapy was significantly more as compared to antibiotics alone.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"214 1","pages":"1628-1631"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78494135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A Study of Prognostic Value of Hs-CRP and Fibrinogen in Patients of Unstable Angina Hs-CRP和纤维蛋白原对不稳定型心绞痛患者预后价值的研究

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18910

Harpreet Singh, Kunal Bansal, T. Singh, Deepa Malik, Vani Bansal, T. Bansal

{"title":"A Study of Prognostic Value of Hs-CRP and Fibrinogen in Patients of Unstable Angina","authors":"Harpreet Singh, Kunal Bansal, T. Singh, Deepa Malik, Vani Bansal, T. Bansal","doi":"10.18311/IJMDS/2018/18910","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18910","url":null,"abstract":"Background: Unstable angina constitutes a clinical syndrome that is usually caused by atherosclerotic coronary artery disease and is associated with an increased risk of cardiac death and myocardial infarction. Material and Methods: An open, prospective, observational, comparative study was conducted. The study included 50 cases in age group 20-80 years admitted in Government Medical College, Amritsar diagnosed as unstable angina ruled out by Trop T and CPK-MB at admission. Hs-CRP and Fibrinogen levels were estimated at time of admission and repeated after 48 hours. Results: There was significant difference in the mean value of Hs-CRP between favourable and unfavourable group at the time of admission (0.807±0.37mg/l v/s 3.57±1.70mg/l, p<0.001). A significant difference in the mean value of Hs-CRP was found between favourable and unfavourable group after 48 hours (0.51±0.22mg/l v/s 4.03±1.84mg/l, p<0.001) There was significant difference in the mean value of fibrinogen between favourable and unfavourable group at the time of admission (356.94±72.50mg/dl v/s 588.60±94.89mg/dl, p<0.001). A significant difference in the mean value of fibrinogen was found between favourable and unfavourable group after 48 hours (309.11±75.25mg/dl v/s 622.60±133.42mg/dl, p<0.001). Conclusion: It is concluded that in patients with unstable angina, elevated levels of Hs-CRP and Fibrinogen at admission indicate an adverse hospital outcome.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"22 1","pages":"1609-1614"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82093483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Probiotics in Health and Disease 健康与疾病中的益生菌

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18919

N. Grewal, Baljit Jassal, Rakesh Kumar

引用次数: 20

A Study of Anti-Hypertensive Drug Prescription Patterns in Hypertensive Post-Menopausal Women 绝经后高血压妇女降压药处方模式的研究

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18907

Ritika Singla, Harcharan Singh, Anita K. Gupta, V. Sehgal

{"title":"A Study of Anti-Hypertensive Drug Prescription Patterns in Hypertensive Post-Menopausal Women","authors":"Ritika Singla, Harcharan Singh, Anita K. Gupta, V. Sehgal","doi":"10.18311/IJMDS/2018/18907","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18907","url":null,"abstract":"Background: Drug prescription in menopause is complex as estrogen deficiency, hypertension (HT) and other risk factors, rapidly increase the risk of cardiovascular diseases (CVD) in post-menopausal women (PMW). Objectives: To evaluate the prescription trends of anti-hypertensive drugs in PMW. Methods: This was an observational, cross sectional study conducted over a period of 1 year, on hypertensive PMW. The prescriptions were evaluated for antihypertensive drug use patterns and also as per WHO core drug indicators. Results: 21.82% of prescriptions had monotherapy, amongst which angiotensin receptor blockers (ARB) (10%) and individually, telmisartan (5.45%) were most commonly prescribed. Majority of prescriptions had two drug therapy (44.09%), among which ARB + beta-blockers (BB) (20.91%) and individually, Telmisartan + Metoprolol (13.64%) were most frequently prescribed. ARB + Diuretic (DI) (9.55%) was the most common fixed drug combination (FDC) prescribed. ARB + BB + DI (10.45%), ARB + 2DI + BB (4.09%) and ARB + 2DI + BB + Calcium channel blocker (1.82%) were most commonly prescribed three, four and ≥five drug combinations, respectively. Hypolipidemic drugs (60.45%) were maximally co-prescribed. Percentage of drugs prescribed by generic name was 4.63% and from essential drug list was 32.62%. Conclusions: A high trend of polypharmacy was observed in hypertensive PMW. HT, being a multifactorial disease, deserves a multidisciplinary and a comprehensive approach in the care of this population subgroup. Knowledge of prescription pattern and thus the rational utilisation of drugs will help achieve better control rates of HT and hence curb down the burden of CVDs in PMW.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"1 1","pages":"1594-1603"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82373451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seroprevalence of Dengue Infection in a Tertiary Care Hospital in Assam 阿萨姆邦三级保健医院登革热感染的血清流行率

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18905

L. Goswami, Chowdhury Runumi, E. S. Rasul

{"title":"Seroprevalence of Dengue Infection in a Tertiary Care Hospital in Assam","authors":"L. Goswami, Chowdhury Runumi, E. S. Rasul","doi":"10.18311/IJMDS/2018/18905","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18905","url":null,"abstract":"Background: Dengue fever (DF) and dengue hemorrhagic fever (DHF) are important arthropod borne viral diseases. Dengue in India has dramatically expanded over the last few decades, with rapidly changing epidemiology. Dengue is emerging as major public health concern in northeast India and spreading with increased morbidity. Objective: This study was carried out to determine the seroprevalence of Dengue infection among patients attending in Fakhruddin Ali Ahmed Medical College and Hospital, Barpeta, Assam during the period 2013-2016. Methods: A retrospective study was done from the year 2013 to 2016. A total of 340 serum samples received in the department of microbiology FAAMCH, were tested for the confirmation of suspected cases of dengue. Dengue NS1 antigen and Dengue IgM antibody ELISA tests were performed for the confirmation of dengue cases. We estimated the incidence by applying age, sex and season adjusted dengue positivity. Results: Out of 340 samples tested, 68 were positive either by NS1 antigen or for IgM antibody ELISA tests. These comprised all age groups of both sexes with higher incidence of cases in young males aged 26–60 years. Conclusion: From this study, it is apparent that dengue surveillance and control should be enhanced by wider use of laboratory testing to confirm dengue as a cause of fever of unknown origin, especially during the local dengue transmission season.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"22 1","pages":"1582-1585"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81752665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Retromandibular Approach for Subcondylar Fractures: A Prospective Study 后下颌入路治疗髁突下骨折:一项前瞻性研究

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18916

G. Tripathi, Divashree Sharma, Sourabh Dixit, A. Bhat, L. Yadav, Rohit Sharma

{"title":"Retromandibular Approach for Subcondylar Fractures: A Prospective Study","authors":"G. Tripathi, Divashree Sharma, Sourabh Dixit, A. Bhat, L. Yadav, Rohit Sharma","doi":"10.18311/IJMDS/2018/18916","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18916","url":null,"abstract":"Background: Condylar fractures accounts for 25-50% of all mandibular fractures. It can be extracapsular or intracapsular, nondisplaced, displaced, deviated, or dislocated from the disc. Objective: To evaluate the retromandibular transparotid approach for open reduction & internal fixation of subcondylar fractures for post-operative occlusal status, stability of fixation & postoperative complications. Material and Methods: The prospective study was performed on 24 patients (18 male and 8 females) sustaining 26 subcondylar fractures who were treated surgically utilizing retromandibular transparotid incision. Results: The most common etiology of injury was road traffic accidents in 62.5% patients. Satisfactory anatomic reduction and occlusion was achieved in all patients. The incidence of transient facial nerve injury was 16.67%. The facial nerve returned to normal function in 3 months in all the 4 affected patients. Conclusion: The incision provides easy visualization of the subcondylar region from the posterior edge of the ramus to the sigmoid notch, allows the perpendicular placement of screws to the fracture site, with minimal post operative complications and satisfactory esthetic results.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"56 1","pages":"1637-1641"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84665817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Histological Patterns of Ovarian Neoplasms – A Five Year Experience in North-East India 卵巢肿瘤的组织学模式-在印度东北部的五年经验

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18904

S. Manasi, Banerjee Alpana, D. Abhijit

{"title":"Histological Patterns of Ovarian Neoplasms – A Five Year Experience in North-East India","authors":"S. Manasi, Banerjee Alpana, D. Abhijit","doi":"10.18311/IJMDS/2018/18904","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18904","url":null,"abstract":"Background: Ovary is one of the common sites of neoplasm in females. They manifest in wide spectrum of clinical, morphological and histological features. Ovary is the second most common site of primary malignancy in female genital tract. Objectives: To study the frequency of different histological types of ovarian tumors and to analyze age distribution of these tumors. Materials and Methods: This was a retrospective study of all cases of ovarian tumors received at Pathology Department of Agartala Government Medical College during the period of 5 years from January 2012 to December 2016. Results: A total number of 242 cases were studied. Among these 189 cases (78.1%) were benign, 12 cases (4.96%) were borderline and 41 cases (16.94%) were malignant. Benign neoplasms were most commonly seen between 3 rd and 5 th decade of age whereas malignant neoplasms after 4 th decade. Serous cystadenoma was the commonest benign tumor followed by mucinous cystadenoma and mature cystic teratoma. Among the malignant surface epithelial tumors, mucinous cystadenocarcinoma was most common, followed by serous cystadenocarcinoma. Conclusion: Benign ovarian neoplasms outnumber the malignant ones in all age groups. Surface epithelial tumors are the most common class of tumors and mucinous cystadenocarcinoma is the commonest malignant neoplasm.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"65 1","pages":"1576-1581"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74166387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Morphometric Study of Axis Vertebra in Subjects of Indian Origin 印度裔受试者中轴椎形态计量学研究

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18911

J. Kaur, Kamaljeet Kaur, Poonam Singh, Ajay Kumar

{"title":"Morphometric Study of Axis Vertebra in Subjects of Indian Origin","authors":"J. Kaur, Kamaljeet Kaur, Poonam Singh, Ajay Kumar","doi":"10.18311/IJMDS/2018/18911","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18911","url":null,"abstract":"Background: The axis vertebra, exhibits complex and extensive variability in the morphology and there are vital neurovascular structures in its proximity. Knowledge of this variability is important for neurosurgeons, orthopaedicians, otorhynologists and other physicians who in everyday practice are in contact with disorders of the spine and their consequences. Objective: The aim was to evaluate various morphometric dimensions of axis vertebrae and to compare with the available data. Material and Methods: 50 dried human axis vertebrae of Indian origin, available in the Department of Anatomy, Dayanand Medical College and Hospital, Ludhiana were studied. Various dimensions were taken with vernier calipers, metric scale and graph paper. The dimensions were measured in millimetres and statistically analysed with paired t-test. Results: The mean of maximum anteroposterior diameter (max.APD) and maximum transverse diameter (max.TD) of Superior Articular Facet (SAF) was measured as 17.42mm±1.73 and 15.31mm±1.44 on the right side, 17.64mm±1.51 and 15.17mm±1.48 on left side. The mean Distance from Lateral most edge of SAF to Midline was measured as 22.56mm ± 2.37 and 22.40mm ± 2.16 on the right and left sides, respectively. The mean Distance from Tip of Transverse Process to Midline was 26.45mm ± 2.85 on the right and 26.03mm ± 2.64 on the left side. The mean Height of Dens was measured as 13.83mm ± 1.52, mean Width of Dens as 9.57mm ± 0.85. Width of Pedicle was measured as 10.52mm ± 1.99 and 10.61mm ± 1.67on right and left sides, respectively. Conclusion: The knowledge of these dimensions can provide useful information for safe planning of osseous fixation.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"14 1","pages":"1615-1620"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84326127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Bernard Soulier Syndrome; A Rare Bleeding Disorder Bernard Soulier综合征;一种罕见的出血性疾病

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18917

P. Tripathi, K. Karthika, H. Pati, S. Tyagi

引用次数: 2

A Study on Concordance of Pre and Post-Surgical Biopsy in Oral Carcinoma 口腔癌术前术后活检一致性的研究

International Journal of Medical and Dental Sciences Pub Date : 2018-01-09 DOI: 10.18311/IJMDS/2018/18915

J. Sebastian, B. Satheesan, Shibu P. Emmnuel, N. C. Sandeepa, S. Asif, S. Kaleem, Bhavna Barthunia

{"title":"A Study on Concordance of Pre and Post-Surgical Biopsy in Oral Carcinoma","authors":"J. Sebastian, B. Satheesan, Shibu P. Emmnuel, N. C. Sandeepa, S. Asif, S. Kaleem, Bhavna Barthunia","doi":"10.18311/IJMDS/2018/18915","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18915","url":null,"abstract":"Background: Clinically suspicious oral lesions are usually first dealt with an incisional biopsy. The management and treatment plan of these entities depends mainly on this report. The disparity in incisional and excisional biopsy report is an important area of concern affecting the patient’s management. Objective: Aim of the study was to compare retrospectively the incisional (presurgical) and excisional (post-surgical) biopsy reports of proven cases of carcinomas. Material and Methods: A total of 98 excisional biopsy cases of proved oral carcinoma were selected. Both incisional and excisional biopsy reports were retrieved. Sex predilection, Frequency of site of tumor, correlation between incisional and excisional biopsy, type of biopsy and change in the status were studied and statistically analyzed. Significance between Pre-biopsy and post biopsy was statistically analyzed using Chi-Square Tests. Results: There was concordance of 66.3% in incisional and excisional biopsy report. 33.7% cases showed disparity. Upgrading in the excisional biopsy report was noted in 15.30% cases. Downgrading was noted in 14.26% cases. When statistically analyzed the difference in pre-and post-biopsy was statistically insignificant. Conclusion: Incisional biopsy was found to have certain restriction in the valuation of Oral lesions. Clinicians should be vigilant the possibility of under diagnosis from incisional biopsy and even undetected carcinoma in the incisional specimen, especially of nonhomogeneous lesions.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"66 1","pages":"1632-1636"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85632705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0