{"title":"A case of blunt liver injury with rare hemodynamics: traumatic outflow block.","authors":"Keita Sato, Natsuki Hashiba, Junji Uraki","doi":"10.1186/s12245-025-00979-0","DOIUrl":"10.1186/s12245-025-00979-0","url":null,"abstract":"<p><strong>Background: </strong>Non-operative management (NOM) has become the standard of care for blunt solid organ injury, with angioembolization (AE) playing a key role in achieving hemostasis, particularly in liver trauma. Although the dual blood supply to the liver provides relative protection against ischemia, AE can disrupt this balance and lead to major hepatic necrosis (MHN), a life- threatening complication associated with significant morbidity and mortality. Early identification of patients at risk of developing MHN is critical but remains challenging. While treatment strategies for MHN have been explored, early predictive markers, especially angiographic findings, remain underreported and are not yet established in the literature. We report a rare intrahepatic hemodynamic phenomenon observed on angiography that may serve as an early predictor of MHN.</p><p><strong>Case presentation: </strong>A 32-year-old man sustained a Grade III liver injury predominantly involving the left hepatic lobe following a motor vehicle collision. Contrast-enhanced CT showed hepatic parenchymal injury with hemoperitoneum. Although no active extravasation was observed, contrast enhancement was noted in the left portal vein branch during the arterial phase. Selective angiography via the left hepatic artery revealed parenchymal enhancement of the left hepatic lobe, followed by retrograde opacification of the left portal vein branch. Notably, contrast did not proceed into the left hepatic vein, suggesting impaired hepatic venous outflow. This hemodynamic pattern, characterized by trans-sinusoidal arterial-to-portal flow without venous drainage, can be termed traumatic outflow block (TOFB), a phenomenon not previously reported in trauma. Despite this atypical flow pattern, AE was performed using gelatin sponge particles. The patient subsequently developed abdominal pain and fever, and CT showed non-perfusion of the lateral liver segment. Emergency surgery confirmed massive hepatic necrosis and lateral segmentectomy was performed. Intraoperatively, there were no observable lacerations or disruptions of the portal vein or hepatic veins. However, the liver parenchyma near the root of the left hepatic vein exhibited substantial contusion and hematoma, suggesting possible venous compression. The patient made an uneventful recovery and was discharged on postoperative day nine.</p><p><strong>Conclusions: </strong>TOFB is a novel angiographic finding suggestive of hepatic venous congestion and may serve as an early predictor of MHN after embolization. While therapeutic strategies for TOFB remain undefined, early recognition of this hemodynamic pattern could guide selective embolization, prompt monitoring and potentially improve outcomes in patients with severe liver trauma.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"180"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case report : pyridaben poisoning induced acute respiratory and circulating failure.","authors":"Dan Zhang, Juan Wang, WeiYi Zhang","doi":"10.1186/s12245-025-00946-9","DOIUrl":"10.1186/s12245-025-00946-9","url":null,"abstract":"<p><strong>Background: </strong>Pyridaben, a commonly employed pyridazinone insecticide, is extensively utilized in safeguarding crops against insects and mites. Pyridaben is known to impede mitochondrial complex I activity, inducing mitochondrial impairment, which subsequently culminates in cellular hypoxia, cessation of glycolysis, swift lactic acid buildup, and the onset of lactic acidosis. Prolonged exposure to pyridaben has been demonstrated to elicit deleterious effects on neuronal cells. Furthermore, pyridaben has been associated with the manifestation of cardiotoxicity, leading to abnormal cardiac function.</p><p><strong>Case presentation: </strong>A 55-year-old Male was expeditiously transported to our medical facility thirty minutes subsequent to ingesting 10 mL of pyridaben. Upon admission, the patient exhibited symptoms of vomiting and coma. Within the next half-hour, he progressed to hypotonic hypoxemia and hypotension as a result of pyridaben intoxication. With the implementation of prompt gastric lavage, oral administration of activated charcoal, respiratory and circulatory support, as well as continuous renal replacement therapy (CRRT), the patient was ultimately discharged successfully without any lingering sequelae.</p><p><strong>Conclusion: </strong>This case report delineates a rare occurrence of acute human poisoning stemming from contact with novel synthetic pesticides. The document elucidates the clinical manifestations observed and the efficacious administration of supportive therapeutic interventions.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"182"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A unique case of atraumatic splenic haematoma likely caused by increased intra-abdominal pressure: a case report.","authors":"Yu Xian Wong, Yi Wen Mathew Yeo, Eleazar Ebreo","doi":"10.1186/s12245-025-00978-1","DOIUrl":"10.1186/s12245-025-00978-1","url":null,"abstract":"<p><strong>Background: </strong>The spleen is a highly vascular organ, and splenic haematoma is a complication most commonly due to abdominal trauma. Atraumatic splenic haematoma is much rarer and is often associated with underlying pathology such as coagulopathies, malignancies, anatomical abnormalities or use of anticoagulants. This case report highlights a unique case of atraumatic splenic haematoma in a young, healthy male, likely precipitated by increased intra-abdominal pressure from persistent cough and weightlifting. It presents a rare cause of atraumatic splenic haematoma that is not commonly documented in literature.</p><p><strong>Case presentation: </strong>The patient is a 21-year-old male, with no known chronic disease. He is a smoker and complained of a persistent cough for the past three months. He presented the day after a gym session, with sudden left hypochondrium tenderness with no history of trauma, vomiting or diarrhoea. Physical exam revealed normal vital signs and generalized involuntary guarding over the entire abdomen. Initial point-of-care ultrasound was negative for free fluid in the abdomen, but a repeat ultrasound three hours later turned positive. Computed tomography scans of the abdomen, pelvis and mesenteric angiogram were then performed. They revealed intraperitoneal blood, a Grade III splenic haematoma involving the superior pole of the spleen towards the inferior pole, but no active bleeding. The patient was admitted for close monitoring. Initial laboratory evaluation did not show any coagulopathy or infection. The patient remained hemodynamically stable throughout his inpatient stay, and was managed conservatively with rest, analgesia, and empirical antibiotics. Serial haemoglobin levels remained stable, and his symptoms resolved with analgesia. As he remained hemodynamically stable, no repeat imaging was performed inpatient. He was subsequently discharged with instructions to avoid strenuous activities for 4 to 6 weeks. An outpatient follow-up was arranged for him, to review symptoms and monitor haemoglobin level.</p><p><strong>Conclusion: </strong>This case highlights a rare case of atraumatic splenic haematoma, possibly related to increased intra-abdominal pressure from persistent coughing and weightlifting. Atraumatic splenic haematoma is rare and might be easily overlooked as a diagnosis in the emergency department. Emergency physicians should maintain a high index of suspicion for splenic injury in patients presenting with unexplained left hypochondrium pain, and bedside ultrasonography can aid in assessment and guide the need for further evaluation.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"176"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ba Loc Nguyen, Yong Jian Cheng, Si Yong Ivan Chua, Choon Chiat Oh
{"title":"Trends in dermatological presentations at the emergency department of a tertiary hospital in Singapore: a 4-year analysis pre- and during COVID-19.","authors":"Ba Loc Nguyen, Yong Jian Cheng, Si Yong Ivan Chua, Choon Chiat Oh","doi":"10.1186/s12245-025-00960-x","DOIUrl":"10.1186/s12245-025-00960-x","url":null,"abstract":"<p><strong>Background: </strong>Skin disorders comprise a significant portion of emergency department (ED) visits. Limited dermatology training among junior ED doctors poses challenges, especially during crises like COVID-19, which introduced resource constraints and new viral rash morphologies. This study examines dermatological ED presentations at Singapore General Hospital, comparing pre-pandemic (2018-2019) and pandemic (2020-2021) trends in diagnosis and disposition patterns.</p><p><strong>Materials & methods: </strong>A retrospective analysis of de-identified electronic health records (2018-2021) was conducted. Data included patient demographics, diagnosis, and disposition (admission, referral, discharge). Diagnoses were classified into major categories, and statistical analyses were performed using Python 3.12 and chi-squared tests.</p><p><strong>Results: </strong>Among 28,621 cases, dermatological presentations declined by 15.6% during COVID-19. Infective conditions remained the most common, with bacterial cellulitis and herpes zoster leading. Inflammatory dermatoses, especially urticaria, atopic, and contact dermatitis, increased during the pandemic. Allergy cases surged in 2021, largely linked to COVID-19 vaccinations. Admissions peaked in 2020, and referrals to dermatologists increased in 2021, while GP referrals declined.</p><p><strong>Conclusion: </strong>Major shifts in dermatological ED trends highlight the impact of PPE usage, vaccinations, and pandemic psychological stressors. Increased admissions and specialist referrals emphasize the need for enhanced dermatology training and resource allocation in emergency medicine for future pandemic preparedness.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"174"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare coincidence of presentation of TIA like illness immediately followed by acute myocardial infarction and cardiac arrest: a case report.","authors":"Meiling Wang, Danping Yan, Sa Wang, Yuwei Wang","doi":"10.1186/s12245-025-00982-5","DOIUrl":"10.1186/s12245-025-00982-5","url":null,"abstract":"<p><p>A 64-year-old man presented with acute left-sided limb weakness and no abnormalities on brain CT perfusion imaging. The patient soon experienced cardiac arrest, and coronary angiography after successful cardiopulmonary resuscitation demonstrated complete occlusion of the anterior descending branch and circumflex branch mid-sections, as well as diffuse lesions in the right coronary mid-section. Atypical AMI manifestations complicate emergency diagnosis, necessitating high clinical vigilance and broad differential assessment during initial evaluation.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"175"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic performance of artificial intelligence for dermatological conditions: a systematic review focused on low- and middle-income countries to address resource constraints and improve access to specialist care.","authors":"Olivier Uwishema, Malak Ghezzawi, Nicole Charbel, Shireen Alawieh, Subham Roy, Magda Wojtara, Clyde Moono Hakayuwa, Ibrahim Khalil Ja'afar, Gerard Nkurunziza, Manya Prasad","doi":"10.1186/s12245-025-00975-4","DOIUrl":"10.1186/s12245-025-00975-4","url":null,"abstract":"<p><strong>Background: </strong>Artificial Intelligence (AI) has emerged as a transformative tool in dermatology, particularly in Low- and Middle-Income Countries (LMICs), where healthcare systems face challenges such as a shortage of dermatologists and limited resources. AI technologies, including deep learning models like Convolutional Neural Networks (CNNs), have demonstrated potential in improving diagnostic accuracy for skin diseases, which contribute significantly to the global disease burden. However, most research has focused on High-Income Countries (HICs), leaving gaps in understanding AI's applicability and effectiveness in LMICs.</p><p><strong>Aim/objective: </strong>This systematic review critically evaluates the application of AI in dermatological practice within LMICs, assessing the performance of AI technologies across diverse geographic regions.</p><p><strong>Methodology: </strong>The review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and included 19 studies from databases including PubMed, Embase, and Cochrane. Eligible studies evaluated AI applications in dermatology within LMICs, reporting metrics like sensitivity, specificity, precision, and accuracy. Data extraction and quality assessment were performed independently by several reviewers using tools like PROBAST and QUADAS-2. A qualitative synthesis as per SWiM guidelines was conducted due to heterogeneity in study designs and outcomes.</p><p><strong>Conclusion: </strong>AI shows significant promise in enhancing dermatological diagnostics and expanding access to dermatologic care in LMICs, with models achieving high accuracy (up to 99%) in tasks like skin cancer and infectious disease detection. However, challenges such as underrepresented skin tones in datasets, limited clinical validation, and infrastructural barriers currently hinder equitable implementation. Future efforts should prioritize creating and utilizing diverse datasets, lightweight models for mobile deployment, and human-AI collaboration to ensure context-specific and scalable solutions. Addressing these gaps can help leverage AI to mitigate global health disparities in dermatological care.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"172"},"PeriodicalIF":2.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Nemati, Mohammad Moshiri, Mobin Gholami, Mahdi Talebi, Leila Etemad, Morteza Talebi Doluee
{"title":"Epidemiology of poisoning in elderly Iranians: a narrative review with global context.","authors":"Ahmad Nemati, Mohammad Moshiri, Mobin Gholami, Mahdi Talebi, Leila Etemad, Morteza Talebi Doluee","doi":"10.1186/s12245-025-00989-y","DOIUrl":"10.1186/s12245-025-00989-y","url":null,"abstract":"<p><strong>Background: </strong>Acute poisoning among elderly populations is a serious health concern with particularly hazardous consequences. This review synthesizes findings from multiple studies investigating acute poisoning among the elderly in Iran and compares them with similar studies in other countries.</p><p><strong>Method: </strong>This study reviews data from several studies conducted in various regions of Iran that investigated acute poisoning among elderly individuals (older than 60 years old). Studies were included that provided information on demographic characteristics and clinical findings in English or Persian up to date.</p><p><strong>Results: </strong>Six studies from five provinces in Iran were analyzed, revealing a consistent male predominance in poisoning cases, particularly among those aged 60-69. Most incidents occurred at home, primarily through oral ingestion. While pharmaceutical agents were initially the primary cause, illicit drug use, particularly opioids, has become increasingly prevalent. Accidental poisoning and drug overdoses were more common among men, whereas suicide attempts were more frequent in women. Clinical presentations often included altered mental status, with average hospital stays of up to 3.5 days. Mortality rates ranged from 3.5 to 11.7%, predominantly due to opioid poisoning.</p><p><strong>Conclusion: </strong>Reviewing international studies highlighted that patterns of poisoning vary between countries, underscoring the need for a context-specific approach. The rise in opioid-related poisonings and distinct patterns observed highlight a critical and evolving public health challenge for elderly Iranians. These findings underscore the urgent need for targeted interventions, including opioid monitoring programs, enhanced access to mental health services through primary healthcare, and community-based support systems. Training caregivers and implementing public health campaigns are also crucial to address this growing concern and improve the safety and well-being of this vulnerable population.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"173"},"PeriodicalIF":2.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Segmental spleen and left kidney infarction induced by vasoconstriction in a methamphetamine abuser patient: a case report.","authors":"Alireza Javidan, Mahdi Rezai, Reza Mosaddegh, Najmeh Zarei Jelyani, Raha Latifaltojar","doi":"10.1186/s12245-025-01011-1","DOIUrl":"10.1186/s12245-025-01011-1","url":null,"abstract":"<p><strong>Background: </strong>Methamphetamine is one of the most used illicit drugs worldwide that affects different systems of the body by an immediate and sustained increase of monoamines. Its effect on the central nervous system (CNS) and neurotoxic effects are best known. There are also many reports of its effects on vasoconstriction in some peripheral and large caliber arteries, which results in different organ and limb disturbances.</p><p><strong>Case presentation: </strong>We report a rare case of a man with simultaneous spleen and left kidney infarction captured on contrast-enhanced computed tomographyeffects, without evidence of thrombosis or atherosclerosis, findings strongly suggestive of methamphetamine-induced vasospasm. The patient's abdominal pain improved under observation within days without apparent tissue loss or organ failure. Unfortunately, the patient passed away as a result of bradycardia and cardiac arrest.</p><p><strong>Conclusion: </strong>This very rare case highlights the potentially severe vasospastic complications of methamphetamine abuse, which may result in multiorgan infarction. The fatal outcome in this patient was primarily due to underlying cardiac disease and endocarditis, although methamphetamine-associated cardiovascular strain could not be excluded as a contributor. Clinicians should consider vascular events in methamphetamine users presenting with atypical abdominal pain or any signs of organ dysfunction.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"170"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"S-100B in acute ischemic stroke: a visualization of global hotspots.","authors":"Samhitha Gurijala, Sofia Malik, Latha Ganti","doi":"10.1186/s12245-025-01007-x","DOIUrl":"10.1186/s12245-025-01007-x","url":null,"abstract":"<p><p>A bibliometric analysis was performed on academic research from 1965 to 2025 with a focus on S-100B protein and acute ischemic stroke (AIS). In total 15,792 academic papers about S-100B protein and AIS were reviewed, showing a sharp incline in publications after 1980. Leading the publications of research and citations were the United States, followed by Japan and Germany, which also had the highest clustered connections as well. The most prevalent organization was the Harvard University. This bibliometric analysis aims to analyze the prognostic value of S-100B protein as a potential biomarker in AIS with global data.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"171"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoffer B Hedegaard, Kasper Iversen, Fredrik Folke, Morten Lock-Hansen, Carolina Malta Hansen, Jannik Pallisgaard
{"title":"Review of current knowledge regarding usage of pre-hospital heart rate variability and complexity in triage and added value for predicting the need for life-saving interventions.","authors":"Christoffer B Hedegaard, Kasper Iversen, Fredrik Folke, Morten Lock-Hansen, Carolina Malta Hansen, Jannik Pallisgaard","doi":"10.1186/s12245-025-00967-4","DOIUrl":"10.1186/s12245-025-00967-4","url":null,"abstract":"<p><strong>Background & aim: </strong>Analysis of heart rate variability metrics has shown added accuracy in pre-hospital trauma triage. These metrics include heart rate variability (HRV), meaning oscillations in the time interval between heartbeats, and heart rate complexity (HRC), which assesses intricate patterns of heart rate over time. This review article evaluates current knowledge regarding HRV and HRC and prediction of a subsequent life-saving intervention (LSI), an intervention executed by trained medical personnel to prolong the life of the patient. Our primary focus was on pre-hospital patients and the utility of HRV and HRC when added to existing trauma triage scores or vital signs such as heart rate (HR).</p><p><strong>Methode: </strong>A literature search was carried out by searching the MEDLINE database via the PubMed website for original research published in English from 2008 to 2023. The combinations of search terms applied yielded 18 original studies of which only six met our criteria. We included another study as it contributed original research beneficial to our article.</p><p><strong>Results: </strong>The studies showed a statistically significant increase in the ∆Area Under Curve (AUC) between 0.14 and 0.40 for predicting risk of LSI when adding the two heart rate variability metrics to existing trauma triage scores or vital signs such as HR. Calculation of HRV and/or HRC could be conducted using ECG recording hardware already accessible in most emergency pre-hospital settings with less ECG noise and therefore higher quality ECG data over time.</p><p><strong>Conclusion: </strong>Both HRV and HRC showed potential for increasing ∆AUC in predicting risk of LSI when added to existing risk triage scores. Calculation of HRV and HRC could potentially be conducted using a preexisting hardware in most emergency pre-hospital settings.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"169"},"PeriodicalIF":2.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12459062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}