Infectious Diseases in Clinical Practice最新文献_第4页

Infectious Diseases in Clinical Practice Pub Date : 2023-10-23 DOI: 10.1097/ipc.0000000000001302

Bilal Irfan, Ihsaan Yasin, Aneela Yaqoob

引用次数: 0

COVID-19 Infection and Diabetes COVID-19感染与糖尿病

Infectious Diseases in Clinical Practice Pub Date : 2023-10-16 DOI: 10.1097/ipc.0000000000001295

Ahmed Fathy Gomaa, Reda M. Elghmary, Mahmoud A. Sharafeddin, Salem Youssef Mohamed, Ayman Fathy Elsayed

{"title":"COVID-19 Infection and Diabetes","authors":"Ahmed Fathy Gomaa, Reda M. Elghmary, Mahmoud A. Sharafeddin, Salem Youssef Mohamed, Ayman Fathy Elsayed","doi":"10.1097/ipc.0000000000001295","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001295","url":null,"abstract":"Abstract Background Hyperglycemia is one of the most important independent risk factors that affect the prognosis and outcome of COVID-19 patients. Coronavirus disease 2019 infection is associated with poor glycemic control. This study's objectives were to determine the effect of hyperglycemia on the prognosis and outcome of COVID-19 patients and to detect whether COVID-19 infection can induce new-onset diabetes. Patients and Methods This cohort study was carried out on 240 hospitalized Egyptian COVID-19 patients, at Zagazig University Hospital isolation intensive care unit, between March 2020 and March 2021. They compared patients with diabetes and uncontrolled hyperglycemia against each other and COVID-19 patients without diabetes or uncontrolled hyperglycemia. Baseline demographic data, clinical features, and laboratory analysis were collected. Clinical outcome was evaluated via hospital stay and survival rate. Patients with uncontrolled hyperglycemia and nondiabetic patients were followed up 1 year after the hospital discharge to detect the development of new-onset diabetes. Result The diabetic group had the highest creatinine level, and the nondiabetic group had a minor C-reactive protein and D-dimer. The difference is significant between diabetic and nondiabetic groups concerning hospital stay. The nondiabetic group had the shortest hospital stay. There is a statistically substantial relationship between mortality and the glycosylated hemoglobin, serum creatinine, C-reactive protein, D-dimer, and serum ferritin. A total of 46.6% of survivors in the uncontrolled hyperglycemic group and 3.4% in the nondiabetic group developed diabetes mellitus during follow-up. There is a statistically significant relationship between new-onset diabetes mellitus and D-dimer. Conclusions Coronavirus disease 2019 can induce diabetes mellitus in vulnerable patients (presented with uncontrolled hyperglycemia at admission). In addition, COVID-19 patients with diabetes or uncontrolled hyperglycemia have worse outcomes and poor prognoses.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"170 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136112525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thromboembolism in Cancer Patients With COVID-19 Infection Compared With Other Infections—A Case Series 2019冠状病毒病(COVID-19)感染的癌症患者血栓栓塞与其他感染的比较——一个病例系列

Infectious Diseases in Clinical Practice Pub Date : 2023-10-16 DOI: 10.1097/ipc.0000000000001305

Mounika Binkam, John N. Greene, Stephanie M. Oehler, Christy Thai, Björn Holmström

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Large Unidentified Neck Mass in an Immunocompetent Patient 免疫功能正常患者颈部不明大肿块

Infectious Diseases in Clinical Practice Pub Date : 2023-10-16 DOI: 10.1097/ipc.0000000000001327

M. Gabriela Cabanilla, Scott V. Norville

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Microsporidial Stromal Keratitis, a Case Report 微孢子性间质角膜炎1例报告

Infectious Diseases in Clinical Practice Pub Date : 2023-10-16 DOI: 10.1097/ipc.0000000000001300

Monchai Duangpraphat, Dhitiwat Changpradub, Worawong Chueansuwan

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Nocardia paucivorans Endophthalmitis and Cerebral Abscesses in an Immunocompetent Patient 免疫功能正常患者的少诺卡菌眼内炎和脑脓肿

Infectious Diseases in Clinical Practice Pub Date : 2023-10-16 DOI: 10.1097/ipc.0000000000001313

Heeral Thakkar, Palaniraj Rama Raj, Annaleise R. Howard-Jones, Paul Adler, Vidthiya Menon

引用次数: 0

Real-World Outcomes of Neutralizing Monoclonal Antibody Treatment in Patients Affected by Nosocomial Coronavirus Disease 2019 中和性单克隆抗体治疗2019院内冠状病毒病患者的现实结局

Infectious Diseases in Clinical Practice Pub Date : 2023-10-06 DOI: 10.1097/ipc.0000000000001307

Lucio Boglione, Federica Poletti, Roberto Rostagno, Roberta Moglia, Marco Cantone, Maria Esposito, Silvio Borrè

{"title":"Real-World Outcomes of Neutralizing Monoclonal Antibody Treatment in Patients Affected by Nosocomial Coronavirus Disease 2019","authors":"Lucio Boglione, Federica Poletti, Roberto Rostagno, Roberta Moglia, Marco Cantone, Maria Esposito, Silvio Borrè","doi":"10.1097/ipc.0000000000001307","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001307","url":null,"abstract":"Introduction Neutralizing monoclonal antibodies (NmAbs) are a treatment option in patients with early SARS-CoV-2 infection. In this study, we examined the role of NmAbs therapies in a cohort of patients affected by nosocomial COVID-19 infection and high risk of illness progression. Methods A retrospective, single-center analysis was performed including all patients affected by nosocomial SARS-CoV-2 infection receiving NmAbs treatment between April 2021 and March 2022. Results The overall included patients were 75. Mortality rate was 13.3%; disease progression was observed in 22 patients (29.3%); clinical improvement was reported in 49 subjects (65.3%). In multivariate logistic regression, the presence of immunosuppression risk factor and late administration of therapies were recognized as independent predictors of treatment failure. Conclusions In this real-world analysis, the treatment with NmAbs was safety and effectiveness in high-risk patients with nosocomial COVID-19 infection, but the timing of administration and the role of viral variants are the main limiting factors of this approach.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134945450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Peritoneal Tuberculosis 腹膜结核

Infectious Diseases in Clinical Practice Pub Date : 2023-10-06 DOI: 10.1097/ipc.0000000000001310

Nazli Begum Ozturk, Christos Tsagkaris, Raim Iliaz

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Rapid Diagnosis of Bartonella-Induced Hemophagocytic Lymphohistiocytosis Using Next-Generation Sequencing of Plasma 利用下一代血浆测序快速诊断巴尔通体诱导的噬血细胞淋巴组织细胞病

Infectious Diseases in Clinical Practice Pub Date : 2023-10-06 DOI: 10.1097/ipc.0000000000001301

Kristin E. Mondy, Rama Thyagarajan, H. Stephen Han, Brian Lee

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A 20-Day Course of Nirmatrelvir/r in a Young Man Newly Diagnosed With Acquired Immunodeficiency Syndrome Carrying Persistent Omicron BA.2 Infection 一名新诊断为获得性免疫缺陷综合征并携带持续性组粒BA.2感染的年轻男性接受尼马特利韦/r治疗20天

Infectious Diseases in Clinical Practice Pub Date : 2023-10-06 DOI: 10.1097/ipc.0000000000001291

Giuseppe Bruno, Claudia Fabrizio, Marilina Tampoia, Maria Chironna, Giovanni Battista Buccoliero

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