International Journal of Critical Illness and Injury Science最新文献

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Gastrointestinal histopathology of acute colchicine toxicity after lower dose treatment of pericarditis: A case report. 小剂量秋水仙碱治疗心包炎急性毒性的胃肠道组织病理学观察。
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 DOI: 10.4103/ijciis.ijciis_105_21
Lisa Liu, Steven Tessier, Rodrigo Duarte-Chavez, Daniel Marino, Anish Kaza, Santo Longo, Sudip Nanda
{"title":"Gastrointestinal histopathology of acute colchicine toxicity after lower dose treatment of pericarditis: A case report.","authors":"Lisa Liu,&nbsp;Steven Tessier,&nbsp;Rodrigo Duarte-Chavez,&nbsp;Daniel Marino,&nbsp;Anish Kaza,&nbsp;Santo Longo,&nbsp;Sudip Nanda","doi":"10.4103/ijciis.ijciis_105_21","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_105_21","url":null,"abstract":"<p><p>Colchicine is an anti-inflammatory alkaloid drug with anti-microtubule activity. Colchicine toxicity is a serious and potentially fatal complication associated with hallmark histopathological features most conspicuous in proliferative tissues such as the gastrointestinal tract. These features have only been reported in patients treated with high doses. We report a patient who experienced acute colchicine toxicity with gastrointestinal histologic changes after treatment with the lowest dose of colchicine. Knowledge of drug-drug interactions and the organs involved in colchicine metabolism is imperative when using colchicine, even when administered at its lowest dose.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"174-176"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective cohort study of short-stay admissions to the medical intensive care unit: Defining patient characteristics and critical care resource utilization. 医学重症监护室短期住院病人的回顾性队列研究:确定患者特征和重症监护资源利用情况。
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 Epub Date: 2022-09-20 DOI: 10.4103/ijciis.ijciis_6_22
Pooja N Pandit, Mark Mallozzi, Rahed Mohammed, Gregory McDonough, Taylor Treacy, Nathaniel Zahustecher, Erika J Yoo
{"title":"A retrospective cohort study of short-stay admissions to the medical intensive care unit: Defining patient characteristics and critical care resource utilization.","authors":"Pooja N Pandit, Mark Mallozzi, Rahed Mohammed, Gregory McDonough, Taylor Treacy, Nathaniel Zahustecher, Erika J Yoo","doi":"10.4103/ijciis.ijciis_6_22","DOIUrl":"10.4103/ijciis.ijciis_6_22","url":null,"abstract":"<p><strong>Background: </strong>Little is known about the mortality and utilization outcomes of short-stay intensive care unit (ICU) patients who require <24 h of critical care. We aimed to define characteristics and outcomes of short-stay ICU patients whose need for ICU level-of-care is ≤24 h compared to nonshort-stay patients.</p><p><strong>Methods: </strong>Single-center retrospective cohort study of patients admitted to the medical ICU at an academic tertiary care center in 2019. Fisher's exact test or Chi-square for descriptive categorical variables, <i>t</i>-test for continuous variables, and Mann-Whitney two-sample test for length of stay (LOS) outcomes.</p><p><strong>Results: </strong>Of 819 patients, 206 (25.2%) were short-stay compared to 613 (74.8%) nonshort-stay. The severity of illness as measured by the Mortality Probability Model-III was significantly lower among short-stay compared to nonshort-stay patients (<i>P</i> = 0.0001). Most short-stay patients were admitted for hemodynamic monitoring not requiring vasoactive medications (77, 37.4%). Thirty-six (17.5%) of the short-stay cohort met Society of Critical Care Medicine's guidelines for ICU admission. Nonfull-ICU LOS, or time spent waiting for transfer out to a non-ICU bed, was similar between the two groups. Hospital mortality was lower among short-stay patients compared to nonshort-stay patients (<i>P</i> = 0.01).</p><p><strong>Conclusions: </strong>Despite their lower illness severity and fewer ICU-level care needs, short-stay patients spend an equally substantial amount of time occupying an ICU bed while waiting for a floor bed as nonshort-stay patients. Further investigation into the factors influencing ICU triage of these subacute patients and contributors to system inefficiencies prohibiting their timely transfer may improve ICU resource allocation, hospital throughput, and patient outcomes.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"127-132"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of National Early Warning Score 2 to risk-stratify coronavirus disease of 2019 patients in the emergency department: A retrospective cohort study. 国家预警评分2对2019年急诊科冠状病毒病风险分层的应用:一项回顾性队列研究
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 DOI: 10.4103/ijciis.ijciis_8_22
Sweta Khuraijam, Alok Gangurde, Vridhi Shetty
{"title":"Utility of National Early Warning Score 2 to risk-stratify coronavirus disease of 2019 patients in the emergency department: A retrospective cohort study.","authors":"Sweta Khuraijam,&nbsp;Alok Gangurde,&nbsp;Vridhi Shetty","doi":"10.4103/ijciis.ijciis_8_22","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_8_22","url":null,"abstract":"<p><strong>Background: </strong>The application of a risk stratification pathway is necessary for the emergency department (ED) to assess the severity of the disease and the need for escalation of therapy. We aimed to implement the National Early Warning Score 2 (NEWS2) pathway at triage to differentiate patients who are stable or critically ill with no invasive investigations at the time of admission during the coronavirus disease of 2019 (COVID-19) era in comparison to other clinical risk scores.</p><p><strong>Methods: </strong>One hundred and four patients were collected from April 1, 2021, to June 1, 2021, during the second wave of the COVID-19 pandemic at an academic medical center in India. The NEWS2 scoring system and the quick sepsis-related organ failure assessment (qSOFA) score were introduced as part of the initial assessment in the triage area of the ED. Data were assessed using the area under the receiving operating characteristic (AUROC) curve for NEWS2 and qSOFA scores, respectively.</p><p><strong>Results: </strong>In the study, NEWS2 classification indicated that 25% of patients required continuous monitoring, of which 12.7% subsequently deteriorated within 24 h of admission and 7% died. Both, NEWS2 (threshold 0; 1, AUROC 0.883; 95%; confidence interval [CI] 0.8-0.966) and qSOFA (threshold 0; 1, AUROC 0.851; 95% CI 0.766-29 0.936) effectively identified COVID-19 patients in the ED at risk for clinical deterioration. There was no significant difference in the diagnostic performance of qSOFA and NEWS2 (DeLong's test <i>P</i> = 0.312).</p><p><strong>Conclusion: </strong>Both NEWS2 and qSOFA effectively-identified COVID-19 patients in the ED at risk for clinical deterioration with no significant statistical difference. However, a triage level risk stratification score can be developed with the inclusion of blood parameters on admission to further validate the practice.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"133-137"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10682382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heister mouth gag aided endotracheal intubation in patients with maxillofacial trauma: A case report. 海斯特口塞辅助气管插管治疗颌面部外伤1例。
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 DOI: 10.4103/ijciis.ijciis_15_22
Karan Singla, Tanvir Samra, Kajal Jain
{"title":"Heister mouth gag aided endotracheal intubation in patients with maxillofacial trauma: A case report.","authors":"Karan Singla,&nbsp;Tanvir Samra,&nbsp;Kajal Jain","doi":"10.4103/ijciis.ijciis_15_22","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_15_22","url":null,"abstract":"<p><p>Securing the airway in patients with maxillofacial trauma is challenging for the anesthesiologist. Pain and facial deformities limit mouth opening and hence direct laryngoscopy. Fractured bone segments, blood, oral secretions, and tissue edema preclude the use of fiber-optic bronchoscopes for intubation of the trachea. We report a successful attempt of orotracheal intubation with a Macintosh blade in a 25-year-old patient with restricted mouth opening with the use of a Heister mouth gag.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"177-179"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The potential effect of iopamidol contrast on renal function in patients infected with SARS-CoV-2 virus: A retrospective cohort study. iopamidol造影剂对SARS-CoV-2病毒感染患者肾功能的潜在影响:一项回顾性队列研究
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 DOI: 10.4103/ijciis.ijciis_92_21
Sarven Tersakyan, Monica Chappidi, Ankit Patel, Kenneth Hainsworth, Abdalhai Alshoubi
{"title":"The potential effect of iopamidol contrast on renal function in patients infected with SARS-CoV-2 virus: A retrospective cohort study.","authors":"Sarven Tersakyan,&nbsp;Monica Chappidi,&nbsp;Ankit Patel,&nbsp;Kenneth Hainsworth,&nbsp;Abdalhai Alshoubi","doi":"10.4103/ijciis.ijciis_92_21","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_92_21","url":null,"abstract":"<p><strong>Background: </strong>Many types of computed tomography (CT) scans require the use of contrast. Acute kidney injury (AKI) is a known adverse effect of intravenous contrast administration. To our knowledge, the effects of low-osmolar contrast agents such as iopamidol on renal function in patients infected with the SARS-CoV-2 virus have never been studied. This study investigates the incidence of AKI following iopamidol contrast administration in patients infected with the SARS-CoV-2 virus.</p><p><strong>Methods: </strong>This retrospective cohort study included two groups: patients who received CT pulmonary angiography who were infected with SARS-CoV-2 virus and those who tested negative for SARS-CoV-2. Data were collected from the electronic medical record of a single hospital from January 1, 2020, to September 15, 2020. AKI was defined using the Kidney Disease: Improving Global Outcomes definition: increase in serum creatinine by ≥0.3 mg/dL (≥26.5 mcmol/L) within 48 h, or increase in serum creatinine to ≥1.5 times baseline, which is known or presumed to have occurred within the prior 7 days, or urine volume <0.5 mL/kg/h for 6 h.</p><p><strong>Results: </strong>AKI occurred in 13.51% of patients in the SARS-CoV-2 positive group and 16.92% of patients in the negative group. Using a two-sample test to compare the equality of proportions (with continuity correction factor), we found there is no significant difference in the two proportions (<i>P</i> = 0.3735).</p><p><strong>Conclusion: </strong>There was no significant difference in the incidence of AKI between SARS-CoV-2 positive and negative groups. Given the limitations of this study, further work must be done on this topic.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"155-159"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of central venous-to-arterial carbon dioxide difference to arterial-central venous oxygen difference ratio to lactate clearance and prognosis in patients with septic shock: A prospective observational cohort study. 感染性休克患者中心静脉-动脉二氧化碳差、动脉-中心静脉氧差、乳酸清除率与预后的相关性:一项前瞻性观察队列研究。
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 DOI: 10.4103/ijciis.ijciis_10_22
Kavya Sindhu, Deepak Malviya, Samiksha Parashar, Chandrakant Pandey, Soumya Sankar Nath, Shilpi Misra
{"title":"Correlation of central venous-to-arterial carbon dioxide difference to arterial-central venous oxygen difference ratio to lactate clearance and prognosis in patients with septic shock: A prospective observational cohort study.","authors":"Kavya Sindhu,&nbsp;Deepak Malviya,&nbsp;Samiksha Parashar,&nbsp;Chandrakant Pandey,&nbsp;Soumya Sankar Nath,&nbsp;Shilpi Misra","doi":"10.4103/ijciis.ijciis_10_22","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_10_22","url":null,"abstract":"<p><strong>Background: </strong>To assess the relationship between the ratio of difference of venoarterial CO<sub>2</sub> tension (P (v-a) CO<sub>2</sub>) and difference of arterio-venous oxygen content (C (a-cv) O<sub>2</sub>), i.e., ΔPCO<sub>2</sub>/ΔCaO<sub>2</sub> with lactate clearance (LC) at 8 and 24 h, to define a cutoff for the ratio to identify LC >10% and >20% at 8 and 24 h, respectively, and its association with prognosis in septic shock.</p><p><strong>Methods: </strong>Adult patients with septic shock were included in this prospective, observational cohort study. Blood samples for arterial lactate, arterial, and central venous oxygen and carbon dioxide were drawn simultaneously at time zero (T0), 8 h (T8), and 24 h (T24). At T8, patients were divided into Group 8A (LC ≥10%) and Group 8B (LC <10%). At T24, patients were divided into Group 24A (LC ≥20%) and Group 24B (LC <20%).</p><p><strong>Results: </strong>Ninty-eight patients were included. The area under the curve of ΔPCO<sub>2</sub>/ΔCaO<sub>2</sub> at T8 (0.596) and T24 (0.823) was the highest when compared to P(v-a) CO<sub>2</sub> and C(a-v) O<sub>2</sub>. The best cutoff of P(v-a) CO<sub>2</sub>/C (a-v) O<sub>2</sub> as predictor of LC >10% was 1.31 (sensitivity 70.6% and specificity 53.3%) and for LC >20% was 1.37 (sensitivity 100% and specificity 50%). At both T8 and T24, P(v-a) CO<sub>2</sub>/C (a-v) O<sub>2</sub> showed a significant negative correlation with LC. Groups 8A and 24A showed lower intensive care unit mortality than 8B and 24B, respectively. Values of P(v-a) CO<sub>2</sub>/C (a-v) O<sub>2</sub> at T8 were comparable, but at T24, there was a significant difference between the survivors and nonsurvivors (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>ΔPCO<sub>2</sub>/ΔCaO<sub>2</sub> predicts lactate clearance, and its 24 h value appears superior to the 8-h value in predicting LC and mortality in septic shock patients.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"146-154"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The risk factors of the functional status, quality of life, and family psychological status in children with postintensive care syndrome: A cohort study. 重症监护后综合征患儿功能状态、生活质量和家庭心理状态的风险因素:一项队列研究。
International Journal of Critical Illness and Injury Science Pub Date : 2022-07-01 Epub Date: 2022-09-20 DOI: 10.4103/ijciis.ijciis_7_22
Saptadi Yuliarto, Kurniawan Taufik Kadafi, Sri Fauziah, Takhta Khalasha, William Prayogo Susanto
{"title":"The risk factors of the functional status, quality of life, and family psychological status in children with postintensive care syndrome: A cohort study.","authors":"Saptadi Yuliarto, Kurniawan Taufik Kadafi, Sri Fauziah, Takhta Khalasha, William Prayogo Susanto","doi":"10.4103/ijciis.ijciis_7_22","DOIUrl":"10.4103/ijciis.ijciis_7_22","url":null,"abstract":"<p><strong>Background: </strong>Intensive care treatment has a side effect of several impairments after hospital discharge, known as postintensive care syndrome (PICS). PICS in children must be well evaluated because PICS can affect their global development and quality of life. Our specific aims are to determine the impact of intensive care treatment and the risk factors which contribute to PICS.</p><p><strong>Methods: </strong>In this observational cohort study, we identified critically ill children treated in intensive care units (ICUs) for more than 24 h and survived. We evaluated the internal and external risk factors of the patients in the intensive care. We interviewed their parents to define the functional status and quality of life of the patients in 7 days before ICU admission and the psychological status of the family at the time of intensive care admission. The interview was repeated in 3 months after the intensive care discharge.</p><p><strong>Results: </strong>There was a significant decrease in functional status and quality of life after intensive care treatment (<i>P</i> < 0.001). However, none of the internal risk factors were significantly associated with PICS. Neurologic involvement in the disease was associated with the significantly reduced functional status of patients, while the severity of the disease was significantly associated with both functional status and quality of life. Our study also showed a significant psychological disorder of the family in the intensive care.</p><p><strong>Conclusion: </strong>The occurrence of PICS in children was associated with the severity of the disease, decreased the functional status and quality of life, and contributed to psychological disorders for the family.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 3","pages":"165-173"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point prevalence of delirium among critically ill patients in Saudi Arabia: A multicenter observational study. 沙特阿拉伯危重病人谵妄的点患病率:一项多中心观察性研究。
International Journal of Critical Illness and Injury Science Pub Date : 2022-04-01 Epub Date: 2022-06-24 DOI: 10.4103/ijciis.ijciis_76_21
Nada S Alqadheeb, Mai S Hashhoush, Abdulrahman M Alharthy, Nasir Nasim Mahmood, Zahra A Alfardan, Rashid Amin, Khalid A Maghrabi, Mohammed A Almaani, Mahmoud S Alyamany, Farhan Zayed Alenezi, Abdulrahman R Alruwaili, Kasim H Alkhatib, Asia S Rugaan, Faisal S Eltatar, Haifa M Algethamy, Abdullah M Abudayah, Alaa E Ghabashi, Galal B ElRakaiby, Khalid F Alkatheeri, Mohammed I Alarifi, Yousef A Al Mubarak, Nadia H Ismail, Israa H Alnajdi, Mohammed Elrazi I Ahmed, Mariam A Alansari, Ahmed O Alenazi, Osama M Almuslim
{"title":"Point prevalence of delirium among critically ill patients in Saudi Arabia: A multicenter observational study.","authors":"Nada S Alqadheeb,&nbsp;Mai S Hashhoush,&nbsp;Abdulrahman M Alharthy,&nbsp;Nasir Nasim Mahmood,&nbsp;Zahra A Alfardan,&nbsp;Rashid Amin,&nbsp;Khalid A Maghrabi,&nbsp;Mohammed A Almaani,&nbsp;Mahmoud S Alyamany,&nbsp;Farhan Zayed Alenezi,&nbsp;Abdulrahman R Alruwaili,&nbsp;Kasim H Alkhatib,&nbsp;Asia S Rugaan,&nbsp;Faisal S Eltatar,&nbsp;Haifa M Algethamy,&nbsp;Abdullah M Abudayah,&nbsp;Alaa E Ghabashi,&nbsp;Galal B ElRakaiby,&nbsp;Khalid F Alkatheeri,&nbsp;Mohammed I Alarifi,&nbsp;Yousef A Al Mubarak,&nbsp;Nadia H Ismail,&nbsp;Israa H Alnajdi,&nbsp;Mohammed Elrazi I Ahmed,&nbsp;Mariam A Alansari,&nbsp;Ahmed O Alenazi,&nbsp;Osama M Almuslim","doi":"10.4103/ijciis.ijciis_76_21","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_76_21","url":null,"abstract":"<p><strong>Background: </strong>Delirium in critically ill patients is independently associated with poor clinical outcomes. There is a scarcity of published data on the prevalence of delirium among critically ill patients in Saudi Arabia. Therefore, we sought to determine, in a multicenter fashion, the prevalence of delirium in critically ill patients in Saudi Arabia and explore associated risk factors.</p><p><strong>Methods: </strong>A cross-sectional point prevalence study was conducted on January 28, 2020, at 14 intensive care units (ICUs) across 3 universities and 11 other tertiary care hospitals in Saudi Arabia. Delirium was screened once using the Intensive Care Delirium Screening Checklist. We excluded patients who were unable to participate in a valid delirium assessment, patients admitted with traumatic brain injury, and patients with documented dementia in their medical charts.</p><p><strong>Results: </strong>Of the 407 screened ICU patients, 233 patients were enrolled and 45.9% were diagnosed with delirium. The prevalence was higher in mechanically ventilated patients compared to patients not mechanically ventilated (57.5% vs. 33.6%; <i>P</i> < 0.001). In a multivariate model, risk factors independently associated with delirium included age (adjusted odds ratio [AOR], 1.021; 95% confidence interval [CI], 1.01-1.04; <i>P</i> = 0.008), mechanical ventilation (AOR, 2.39; 95% CI, 1.34-4.28; <i>P</i> = 0.003), and higher severity of illness (AOR, 1.01; 95% CI, 1.001-1.021; <i>P</i> = 0.026).</p><p><strong>Conclusion: </strong>In our study, delirium remains a prevalent complication, with distinct risk factors. Further studies are necessary to investigate long-term outcomes of delirium in critically ill patients in Saudi Arabia.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 2","pages":"70-76"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40512710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surveillance study of bloodstream infections, antimicrobial use, and resistance patterns among intensive care unit patients: A retrospective cross-sectional study. 重症监护病房患者血液感染、抗菌素使用和耐药性模式的监测研究:一项回顾性横断面研究。
International Journal of Critical Illness and Injury Science Pub Date : 2022-04-01 Epub Date: 2022-06-24 DOI: 10.4103/ijciis.ijciis_70_21
Mera A Ababneh, Mohammad Al Domi, Abeer M Rababa'h
{"title":"Surveillance study of bloodstream infections, antimicrobial use, and resistance patterns among intensive care unit patients: A retrospective cross-sectional study.","authors":"Mera A Ababneh,&nbsp;Mohammad Al Domi,&nbsp;Abeer M Rababa'h","doi":"10.4103/ijciis.ijciis_70_21","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_70_21","url":null,"abstract":"<p><strong>Background: </strong>Bloodstream infections (BSIs) are one of the most critical illnesses requiring intensive care unit (ICU) admission. This study assessed patterns of antimicrobial use and resistance in ICU patients with BSIs.</p><p><strong>Methods: </strong>Inpatients admitted to the ICU and who received at least one antimicrobial agent between January 1, 2017, and December 31, 2019, were included in the study. Electronic patients' medical records were used to collect patients' demographic, clinical, and microbiological data.</p><p><strong>Results: </strong>A total of 1051 patients were enrolled in the study, where 650 patients (61.84%) were treated with three or more antimicrobial agents. The most frequently used antimicrobials were piperacillin/tazobactam followed by teicoplanin, meropenem, and levofloxacin. The most predominant multidrug-resistant pathogens were <i>Acinetobacter baumannii</i>, followed by <i>Escherichia coli, Methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumonia,</i> and <i>Pseudomonas aeruginosa</i>.</p><p><strong>Conclusions: </strong>The administration of the antimicrobials among ICU patients was highly based on a combination of three or more broad-spectrum agents. MDR pathogens were found to be highly prevalent among ICU patients with BSI. Therefore, we suggest recommending that hospital policies should apply the antimicrobial stewardship protocols, infection control, and implement antimicrobial de-escalation protocol to reduce the harm pressure of antimicrobial resistance.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 2","pages":"82-90"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40512729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Approach to new-onset facial nerve palsy in a critically ill patient: A case report. 危重病人新发面神经麻痹1例。
International Journal of Critical Illness and Injury Science Pub Date : 2022-04-01 Epub Date: 2022-06-24 DOI: 10.4103/ijciis.ijciis_94_21
Saumitra Misra, Saurabh Kumar, Nitin Rai, Sai Saran
{"title":"Approach to new-onset facial nerve palsy in a critically ill patient: A case report.","authors":"Saumitra Misra,&nbsp;Saurabh Kumar,&nbsp;Nitin Rai,&nbsp;Sai Saran","doi":"10.4103/ijciis.ijciis_94_21","DOIUrl":"https://doi.org/10.4103/ijciis.ijciis_94_21","url":null,"abstract":"<p><p>Lower motor type of facial nerve palsy (Bell's palsy) is one of the most common types of facial nerve palsy, with well-defined management with steroids and antivirals for patients attending outpatient clinics. The diagnosis and management of facial nerve palsy in critically ill patients require an individualized approach, as there may be many other causes like soft-tissue compression due to facial edema which can occur as a complication of prone ventilation and severe subcutaneous emphysema. This report highlights the challenges in the management of new-onset facial nerve palsy diagnosed in the intensive care unit (ICU) for a patient on mechanical ventilation, and creates a necessity for a standard operating protocol for the management of such scenarios in ICU.</p>","PeriodicalId":13938,"journal":{"name":"International Journal of Critical Illness and Injury Science","volume":"12 2","pages":"115-117"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40512733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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