International journal of biomedical research最新文献_第7页

Split face comparative study for efficacy of microneedling alone versus microneedling combined with vitamin c in treating facial acne scars 微针单独与微针联合维生素c治疗面部痤疮疤痕的疗效对比研究

International journal of biomedical research Pub Date : 2017-11-30 DOI: 10.7439/IJBR.V8I11.4445

R. Chakrawarty, M. Jaiswal

{"title":"Split face comparative study for efficacy of microneedling alone versus microneedling combined with vitamin c in treating facial acne scars","authors":"R. Chakrawarty, M. Jaiswal","doi":"10.7439/IJBR.V8I11.4445","DOIUrl":"https://doi.org/10.7439/IJBR.V8I11.4445","url":null,"abstract":"Background: Microneedling a newer treatment modality for facial acne scars induces collagen production through mechanical stimulation of the dermis and leads to the softening of scars, realignment of collagen bundles and stimulation of new collagen. Topical vitamin C have beneficial effect on acne and improves acne scarring when used in conjunction with glycolic acid peels and post-laser resurfacing. Aims: Split face comparative assessment of the efficacy of microneedling therapy versus microneedling therapy in conjunction with topical vitamin C in facial acne scars. Materials and Methods: This study was performed on 50 patients having facial acne scars after taking informed written consent. The face was divided into right and left half from midline. On the half of face only microneedling and on other side of face microneedling therapy with topical vitamin C (5% L-ascorbic acid) has been used. A total of three session at 4 weeks interval was done in each patient. Facial scars was assessed clinically to grade the severity of scarring, as per the ECCA grading system. Results: Gradual improvement in global score & acne scar types after each sitting of Microneedling as well as Microneedling + Topical Vitamin-C observed. Overall mean percentage improvement with Microneedling + Topical Vitamin-C was more than the mean percentage improvement with Microneedling alone. Conclusion: Microneedling shows significant clinical improvement in the M type scars (rolling), and U type scars (boxcar) and modest improvement in V type scars (ice-pick). Effect of microneedling is enhanced by combining the procedure with application of topical vitamin C.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"21 1","pages":"598-604"},"PeriodicalIF":0.0,"publicationDate":"2017-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84588543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Anaesthesiologist in the management of Pericardial Mass in one month old child 麻醉医师在1月龄儿童心包包块处理中的作用

International journal of biomedical research Pub Date : 2017-11-30 DOI: 10.7439/IJBR.V8I11.4505

L. Vali, Apeksha A Bhure

引用次数: 0

Prevalence of Hepatitis B and C in Blood Bank Donors in SVNGMC Yavatamal SVNGMC血库献血者乙型和丙型肝炎患病率

International journal of biomedical research Pub Date : 2017-11-30 DOI: 10.7439/IJBR.V8I11.4494

Snehal F. Jumnake, Jayawant Mahadhani, Sanjay Khandekar, Nilima D. Lodha, S. Hingway

{"title":"Prevalence of Hepatitis B and C in Blood Bank Donors in SVNGMC Yavatamal","authors":"Snehal F. Jumnake, Jayawant Mahadhani, Sanjay Khandekar, Nilima D. Lodha, S. Hingway","doi":"10.7439/IJBR.V8I11.4494","DOIUrl":"https://doi.org/10.7439/IJBR.V8I11.4494","url":null,"abstract":"Background: Infections caused by the hepatitis B virus (HBV) and hepatitis C virus (HCV) are global public health problems. The safety of donated blood can be estimated by monitoring the prevalence of viral markers in the donor population. The present study was carried out in Yavatmal region of Maharashtra state, with an objective to determine the prevalence of HBV and HCV among blood bank donors. Methods: Over a period of three years (January 2014 to December 2016), a total of 33082 blood units were collected from healthy voluntary and replacement blood donors. The donated units were serologically screened for hepatitis B surface antigen (HBsAg) and antibody to hepatitis C virus (anti-HCV). Results: Out of total blood donors, 93.67% were males and 6.32% were females. HBsAg was positive in 284 (0.85%) of the blood units that were collected, the blood units with antiHCV seropositivity had the lowest prevalence (n=9, 0.027%) and these prevalence being higher in males than females. The prevalence of HBsAg was highest in the year of 2015 (0.93%) compared to 2014 (0.85) and 2016 (0.78). There was decline in the prevalence of HCV infection has been observed, from 0.039% in 2014 to 0.016% in 2016. Conclusion: The study reveals that the decrease in HBV and HCV prevalence among blood bank donors in SVNGMC Yavatmal might be associated with the introduction of immunization programs, and an increased awareness of hepatitis B throughout the country.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"193 1","pages":"646-650"},"PeriodicalIF":0.0,"publicationDate":"2017-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79426886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Phosphorus level: A marker of myocardial infarction. 血清磷水平:心肌梗死的标志。

International journal of biomedical research Pub Date : 2017-11-30 DOI: 10.7439/IJBR.V8I11.4450

Neha D. Sheth, H. Sirajwala

引用次数: 0

Assessment of peripheral neuronal activity with Nerve Conduction Studies in subclinical hypothyroidfemales from rural area of Bankura district of West Bengal 西孟加拉邦班库拉农村地区亚临床甲状腺功能减退女性周围神经元活动的神经传导研究

International journal of biomedical research Pub Date : 2017-11-28 DOI: 10.7439/IJBR.V8I11.4454

Piyali Das, P. Pradhan, Sharmistha Ghoshal

{"title":"Assessment of peripheral neuronal activity with Nerve Conduction Studies in subclinical hypothyroidfemales from rural area of Bankura district of West Bengal","authors":"Piyali Das, P. Pradhan, Sharmistha Ghoshal","doi":"10.7439/IJBR.V8I11.4454","DOIUrl":"https://doi.org/10.7439/IJBR.V8I11.4454","url":null,"abstract":"Objective : Like overt cases, whether subclinical hypothyroidism also causes supressed neuronal transmission is still debated . In this study, we tried to explore whether neuronal transmission is impaired in peripheral nerves in subclinical hypothyroidism with the help of Nerve Conduction Studies. Methods: 30 subclinical hypothyroid cases and 30 age sex matched euthyroid control were examined. All the subjects were assessed for Nerve Conduction velocity (NCV).Latency ,amplitude of CMAP(Compound Motor Action Potential) and conduction velocity of peripheral nerves like median and ulnar of both hands were considered. Findings were compared between groups by unpaired Students T- test andassociation among thyroid function parameters and NCV findings were tested by Pearsons co efficient of correlation (r value). Every where p< 0.05 was considered as significant. Results: Subclinical hypothyroids showed significantly higher distal latencies but lower conduction velocities of both median and ulnar nerves than the euthyroid controls (p<0.05 in each case). Amplitude of CMAP of both the nerves were not significantly different between the groups.Level of T3 was found to have a significant negative correlation withdistal latencies of Median and ulnar nerves (r value = -0.51 and -0.38 respectively, P<0.05 in each case) whereas a positive correlation with their conduction velocities (r- value = 0.27 and 0.55 respectively, p< 0.05 in each case). TSH however did not show any significant correlation with NCV parameters. Conclusion: Subclinical hypothyroidism may cause impairment in peripheral nerve conduction but the severity of such neurodeficit is not correlated with the level of TSH but with the level of T3.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"15 1","pages":"605-608"},"PeriodicalIF":0.0,"publicationDate":"2017-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75119944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A comparison between 0.25% bupivacaine and 0.25% ropivacaine in caudal anaesthesia in paediatric patients undergoing lower abdominal surgeries 0.25%布比卡因与0.25%罗哌卡因在小儿下腹部手术患者尾侧麻醉中的比较

International journal of biomedical research Pub Date : 2017-11-28 DOI: 10.7439/IJBR.V8I11.4490

Darshana Kumbhre, R. Jain

{"title":"A comparison between 0.25% bupivacaine and 0.25% ropivacaine in caudal anaesthesia in paediatric patients undergoing lower abdominal surgeries","authors":"Darshana Kumbhre, R. Jain","doi":"10.7439/IJBR.V8I11.4490","DOIUrl":"https://doi.org/10.7439/IJBR.V8I11.4490","url":null,"abstract":"Aims and Objectives: The present study was undertaken to compare the onset time, duration of action of sensory and motor blockade and postoperative pain relief between 0.25% bupivacaine and 0.25% ropivacaine in caudal block for children undergoing lower abdominal surgeries. Method: In a double blind study, 50 patients of (age 2-8 years) ASA grade I and II were randomly allocated in two equal groups to received 0.75ml/ kg of either 0.25% bupivacaine (Group I) or 0.25% ropivacaine (Group II) via caudal epidural route. Caudal block was performed in all patients after induction of anesthesia with sevoflurane and oxygen. All the results were tabulated and analyzed statistically. For all statistical analysis, the level of significance was P 0.05). The duration of motor block in group I was 142.227.77 minutes while in group II it was 120.623.51 minutes (p 0.05). The mean pain score of patients in both groups were comparable. Conclusion: Bupivacaine and Ropivacaine provides almost similar duration of pain relief postoperatively but ropivacaine provides less motor blockade as compared to bupivacaine, making it a suitable agent for day care surgery with increase safety margin particularly in younger children.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"11 1","pages":"641-645"},"PeriodicalIF":0.0,"publicationDate":"2017-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84494614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and risk factors of hypertension among young medical students: An observational study 年轻医学生高血压患病率及危险因素:一项观察性研究

International journal of biomedical research Pub Date : 2017-11-28 DOI: 10.7439/IJBR.V8I11.4467

T. Rao, J. Jain, Richa Chaudhary

{"title":"Prevalence and risk factors of hypertension among young medical students: An observational study","authors":"T. Rao, J. Jain, Richa Chaudhary","doi":"10.7439/IJBR.V8I11.4467","DOIUrl":"https://doi.org/10.7439/IJBR.V8I11.4467","url":null,"abstract":"Background: Hypertension is a chronic disease which over the years can predispose to stroke, heart failure and chronic kidney disease. So, longer hypertension is present more adverse events are observed. This makes it important to diagnose and control hypertension at an early stage in life. Like most developing countries data on hypertension among young especially medical students are scarce in India. We aimed to determine the prevalence and risk factors of hypertension among young medical students of MGIMS Sevagram. Methods: This cross-sectional study was conducted between August, 2010 and March 2013 in MGIMS Sevagram, a rural based teaching hospital in Wardha District of Maharashtra state of India. Total of 765 students, aged 17-35 years, were studied and their data using a WHO STEPS questionnaire,which included socio-demographic characteristics and risk factors of hypertension, were collected. Blood pressure and anthropometric measurements for obesity were performed using standardized protocols. Blood samples for fasting lipid profile were collected. Statistical analysis was done using STATA 13 software. Results: The prevalence of hypertension was found to be 3.53% and 32.16% students had prehypertension. 41.12% of those already on treatment for hypertension had uncontrolled hypertension. After multivariate logistic regression analysis hypertension risk was significantly higher among alcoholics {OR-3.47 (95% CI 1.91-11.23)}, those with positive family history of hypertension {OR-3.47(95% CI 1.91-11.23 )} those with abnormal waist circumference{OR-4.64 (95% CI 1.44-14.94)} and abnormal waist hip ratio{OR-3.64(95% CI 1.33-10.21)}. Conclusion: This study has found a significant burden of hypertension and prehypertension among young medical students. Despite having adequate knowledge and access to management, large proportion of hypertensive medical students didnt have adequate blood pressure control.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"1 1","pages":"609-613"},"PeriodicalIF":0.0,"publicationDate":"2017-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76016762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of post-menopausal osteoporosis in leprosy patients using one-monthly oral Ibandronate administration 每月口服依班膦酸盐治疗麻风病患者绝经后骨质疏松症

International journal of biomedical research Pub Date : 2017-11-21 DOI: 10.7439/IJBR.V8I11.4468

S. Nagpure, R. Kale, S. Pathak, Satyavan Patel

{"title":"Management of post-menopausal osteoporosis in leprosy patients using one-monthly oral Ibandronate administration","authors":"S. Nagpure, R. Kale, S. Pathak, Satyavan Patel","doi":"10.7439/IJBR.V8I11.4468","DOIUrl":"https://doi.org/10.7439/IJBR.V8I11.4468","url":null,"abstract":"Objective: To study the effects of once monthly regimen of Ibandronate on bone marrow density, severity of osteoporosis and quality of life in postmenopausal osteoporotic leprosy patients. Materials and Methods: Out of 204 eligible participants, written consent was given by 200 participants who were hence enrolled for the study. These 200 patients with postmenopausal osteoporotic leprosy were administered with Ibandronate tablet (150mg) as once monthly from October 2010 to October 2011. Patients were analyzed for BMD, severity of osteoporosis and quality of life index. Results: The percentage change in the hip BMD at first follow up was increased by 8.83%. and with second follow up it was increased by 14.51%. A total of 4 patients were in Singhs Index Grade I, 128 patients in Grade II and 60 patients in Grade III severity at the baseline screening. No study dropouts were found for entire 1 year of treatment duration, that is 100% adherence were observed in subjects undergoing treatment. Conclusion: Monthly regimen of Ibandronate confirmed having better tolerability and adherence in postmenopausal osteoporotic leprosy patients. The present study was grounded on the assumption that osteoporotic postmenopausal leprosy patients often experience low levels of quality of life. This was substantiated by the findings, where majority of females in showed improvement in their QOL, with reference to physical activity and pain, limitations to daily activities, change in emotional status and general health status.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"170 1","pages":"623-629"},"PeriodicalIF":0.0,"publicationDate":"2017-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74871569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum nitric oxide levels in chronic renal failure patients on maintenance hemodialysis 维持血液透析的慢性肾衰竭患者血清一氧化氮水平

International journal of biomedical research Pub Date : 2017-11-01 DOI: 10.7439/IJBR.V8I10.4444

Mohammed Mounuddin, B. Laxmikanth

{"title":"Serum nitric oxide levels in chronic renal failure patients on maintenance hemodialysis","authors":"Mohammed Mounuddin, B. Laxmikanth","doi":"10.7439/IJBR.V8I10.4444","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4444","url":null,"abstract":"Background: Nitric oxide (NO) is an endothelium derived vasodilator. NO regulates renal function through modulation of vascular tone. With the progressive development of renal insufficiency, it remains unclear whether endogenous NO production is increased or decreased in the kidney. Aim: This study was carried out to evaluate NO levels and its correlation to routine parameters of renal dysfunction in patients of chronic renal failure (CRF) on maintenance hemodialysis (MHD) in comparison to healthy controls. Material and Methods: 30 CRF patients on MHD with serum creatinine levels >2.5 mg/dl were included in the study along with 30 healthy controls. Serum NO was estimated by spectrophotometric method using cadmium reduction. Routine renal function tests; blood urea nitrogen (BUN) and creatinine were performed by standard clinical chemistry procedures. The between-group differences and between-variable correlations were studied by the independent sample t-test and Pearson correlation analyses, respectively. The receiver operating characteristic curve (ROC) analysis was performed to obtain the sensitivity, specificity and area under curve (AUC) values for serum NO. Results: The serum NO levels were found to be significantly increased (p 0.01) in CRF on MHD (96.5 26.22 ?mol/l) as compared to the controls (40.57 13.36 ?mol/l). NO output correlated with serum creatinine (r=0.615, p 0.01) and BUN (r=0.584 ,p= 0.01) in the CRF group. The ROC analysis on serum NO discriminated between CRF patients and controls with good sensitivity (93.3%), specificity (96.1%) and AUC (0.95) results at a cut-off value of 72.5 mol/L. Conclusions: Our study findings of increased serum NO level and its significant positive correlations with BUN and creatinine in CRF patients on MHD suggests an altered endothelial function in CRF patients on MHD. This increase in serum NO has been found to be useful in discriminating patients from controls.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"84 1","pages":"576-579"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86204528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Recurrent florid vulval warts in a human immunodeficiciency virus reactive patient: excision 人类免疫缺陷病毒反应性患者复发性红润外阴疣:切除

International journal of biomedical research Pub Date : 2017-11-01 DOI: 10.7439/IJBR.V8I10.4383

I. Shambe, C. Obu

引用次数: 0