International journal of biomedical research最新文献

{"title":"Imbalances of both systolic and diastolic hypertension is implicated by a series of causative agents, a cross-sectional health survey","authors":"Rupom Mitra, A. Towhid, Md. Habibur Rahman, Md. Al Amin, D. N. Roy","doi":"10.7439/IJBR.V9I2.4422","DOIUrl":"https://doi.org/10.7439/IJBR.V9I2.4422","url":null,"abstract":"Background and Objectives: Hypertension (HTN) or high blood pressure is a chronic medical condition in which the blood pressure in the arteries is elevated. Blood pressure is summarized by two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed between beats (diastole). Our survey based study is carried out to estimate the current consequences of HTN among the populations of southern cities in Bangladesh. Methods: We have conducted our research in context on population’s age, gender, family history, addictive probability with type of drug habit, age of onset of respondents. We have compared systolic value with diastolic regarding these parameters by the help of self-designed standard questionnaire relevant with hypertension by manual data collection over six month’s period. Total 350 subject respondents were investigated by majorly visiting at their home, work places and hospitals. Descriptive statistics were applied to the collected data and analyzed using Microsoft Excel software. Results: 52.8% was male respondents and 47.8% was female of which 27.3% was the age range 56-65 years and another top most 23.4% was 46-55 years old. 90-100 mm/Hg diastolic value was noticed for 84.9% participants whereas 101-110mm/Hg was for remaining 9.3%. On the other hand, 140-150 and 151-160mm/Hg systolic pressure measured for 36.1% and 26.8% patients. Although 43.4% respondents answered yes in question for conveying hypertension from their family history but 56.6% was not at all. Narcotics substances immensely do impact in high blood pressure pathogenesis as it has showed almost 54.63% users among them betel & tobacco are experienced at least 71% following for smoking 29%. However, 68% betel & tobacco consumers had diastolic pressure 90-100 mm/Hg and 140-150 mm/Hg systolic value was measured for 37% betel and tobacco addicts followed by 26% chain smokers persist systolic pressure 151-160 mm/Hg range. Interestingly the maximum numbers of 32.2% peoples was first affected by hypertension in their age 36-45 years and 24.9% was the age range of 46-55 in second position. Conclusion: Hypertension is a major public health problem and it is diagnosed on the basis of a persistent high blood pressure. Unfortunately, the tendency to start hypertension in young age is increasing day by day. Everybody should be very conscious about this severe health issue to give up all kind of habit forming narcotic agents.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"9 1","pages":"66-71"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81184700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender based inequality in care seeking of under five children","authors":"Nilesh Gothi, G. Kumar, Aditi Gothi","doi":"10.7439/IJBR.V9I2.4626","DOIUrl":"https://doi.org/10.7439/IJBR.V9I2.4626","url":null,"abstract":"Objective: The objective of present study is to assess difference in treatment seeking behavior of families in urban slums for their male and female child. Methods: Study was carried out in urban slums of Udaipur city. Total 34 slums were clustered in the city. Six families were selected from every cluster. Results: Ratio between male and female children was 1:1. Most of the families chose unqualified care providers for girls as compared to boys. Expenditure on health care was more for boys. Conclusion: Utilization of government medical facilities was very less by rural population and even lesser in case of girls. There appear to be significant difference in seeking care for male and female child.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"23 1","pages":"86-87"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82111916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extra-pulmonary tuberculosis - A retrospective study","authors":"A. Poudyal, R. Gurung, N. Poudyal, R. Baral, B. Khanal, S. Bhattacharya","doi":"10.7439/ijbr.v9i1.4521","DOIUrl":"https://doi.org/10.7439/ijbr.v9i1.4521","url":null,"abstract":"Background: Tuberculosis can occur in various organ systems of human body. In the recent years, there has been an increase in the occurrence of extra-pulmonary tuberculosis (EPTB) worldwide. As very little data is available regarding the situation of EPTB in Eastern Nepal, this study was conducted to assess its frequency in various organ systems of the body and to evaluate the role of demographic factors like sex and age in its causation. Aim : To see the prevalence of EPTB among the patient attending a tertiary care hospital, BPKIHS. Methods: Extrapulmonary specimens received for Acid Fast Bacilli (AFB) microscopy in the TB Laboratory, BP Koirala Institute of Health Sciences, Dharan from 1 st July 2010–30 th June 2011 were included in the study. Age, sex and origin of specimens were retrieved and analyzed. Results: High male prevalence was noted with Male: Female ratio of 1.6:1. Maximum specimens were received from age group 0-15 years followed by 16-30years. Body fluids were the most common specimen submitted for EPTB examination. Out of 1823 suspected cases of EPTB, 11 cases were found to be positive by microscopic method, out of the positives cases eight were male and remaining were female. Conclusion: EPTB is high amongst male in their productive age. Tubercular lymphadenitis is the most common form of EPTB. Introduction of newer and rapid method for the diagnosis of EPTB is utmost necessary for country like ours where diagnosis of Extrapulmonary Tuberculosis is still a challenge.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"40 1","pages":"08-11"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74461862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study of oral clonidine and oral gabapentin in attenuation of pressor response to direct laryngoscopy and tracheal intubation","authors":"J. Galat, C. Upasani","doi":"10.7439/IJBR.V9I1.4598","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4598","url":null,"abstract":"Background: Laryngoscopy and intubation causes reflex sympatho-adrenal response in the form of tachycardia and hypertension. The hemodynamic responses during laryngoscopy and endotracheal intubation should be abolished to balance the myocardial oxygen supply and demand which is a key note in the safe conduct of anaesthesia. The present study compared the effect of oral clonidine with oral gabapentin for attenuating hemodynamic pressor responses to laryngoscopy and tracheal intubation. Methods: Total ninety patients of ASA grade I and II, age between 18-50 years, BMI 18 to 25 and who were posted for elective surgeries under general anesthesia were selected for the study. They were divided into three groups of 30 patients in each. Group P received oral placebo (control), group –C received 0.2mg of oral clonidine and group G received 800mg oral gabapentin. Heart rate, systolic blood pressures, diastolic blood pressures mean blood pressures and rate pressure product were noted before induction, after induction, during laryngoscopy and 1,2,3,4,5,10 and 15 minutes after laryngoscopy and intubation. Results: There was significant rise in hemodynamic parameters after laryngoscopy and intubation. Oral clonidine (0.2 mg) and oral gabapentin (800 mg) when given 90mins prior to surgery effectively attenuated the rise in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure and rate pressure product to laryngoscopy and intubation as compared to oral Placebo. Conclusion: Both the drugs, tablet  clonidine 0.2mg and capsule  gabapentin 800mg when given orally  was found to be safe and without any side effects like hypotension and bradycardia.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"27 1","pages":"49-53"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81404281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience of human milk banking from tertiary care centre of South Rajasthan","authors":"Badrilal Meghwal, Manisha Balai, B. Jain","doi":"10.7439/IJBR.V9I1.4594","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4594","url":null,"abstract":"Background and objective: Human milk bank plays an essential role by providing human milk to infants who would otherwise not be able to receive human milk. This retrospective study was carried out to review the basic characteristics of donors and recipients, and the amounts and contamination of breast milk donated at the human milk bank from a tertiary care hospital in South Rajasthan. Materials and methods: Milk banks collect, screen, store, process, and distribute human milk. Data regarding clinical characteristics of the donor mother and recipients, and collected human milk for a period of 9 months (April – December 2017) were obtained from medical records and analysed. Results: The donor pool consisted of 3117 mothers with total sittings of milk donation being 6787. Maximum number (1763; 56.5%) of donor mothers were recruited from gynaecological indoor units. A total of 789.8 L milk was collected, and 767.4 L milk was processed. There were 1492 neonate beneficiaries. Preterm neonates were the most common beneficiaries. Conclusion: Human milk banks serve a vital function by providing human milk for premature infants, sick or hospitalized infants and others who, for a variety of reasons, would otherwise not have access to mothers’ milk. The use of donor milk is widely endorsed. Additionally, establishing a nationwide network of human milk banking and successfully integrating human milk banking services with newborn care will further contribute to the progress of milk banking and reducing preventable newborn deaths.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"64 1","pages":"32-35"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90441726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retracted: Saliva: A systematic review on its diagnostic utility","authors":"Neeharika Mortha, D. Uppala, N. Kothia, S. Majumdar, K. Sravya","doi":"10.7439/IJBR.V9I1.4233","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4233","url":null,"abstract":"Introduction: A paradigm shift in recent years has led to the consideration of the oral cavity (and, thus, oral disease) not in isolation but as a component integrated with systemic physiology, important in maintaining systemic health and reflective of systemic disease. Saliva has been studied extensively as a potential diagnostic tool over the last decade due to its ease and non-invasive accessibility along with its abundance of biomarkers. Aim & Objective: This is a systematic review of the studies published in past 15 years in electronic databases regarding the utility of saliva as a diagnostic tool Materials & Methods: Data collection from electronic databases, followed by data extraction and management. Results & Conclusion: Of 85 studies considered among 510, represent the evolution of saliva in screening neoplasm, with 34 different analytes detected in this population followed by 22 in metablic disorders and the least being in systemic disorders. Most abundantly applied technique being ELISA, common analyte being Immunoglobulins. The application of high throughput proteomic techniques in various studies in the past decade has led to the discovery of new biomarkers.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"244 1","pages":"26-31"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74493738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of the clinical and etiological profile of patients presenting with Congenital Heart Diseases","authors":"K. Jain, B. Jain, D. Sareen","doi":"10.7439/IJBR.V9I1.4601","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4601","url":null,"abstract":"Introduction: Congenital Heart Diseases are amongst the major congenital malformations contributing to infant mortality. Most CHDs are diagnosed in infancy and cyanosis and cardiac failure are the principal signs. Later, in childhood or adolescence, CHD patients may present differently. Objective: To Study the clinical & Etiological profile of Patient presenting as CHD. Material and Methods : This prospective study was conducted in Dept. of pediatrics, RNT Medical College, Udaipur. 100 children having sign and symptoms suggestive of CHD, attending the Balchikitsalay, were included in this study. Each case worked out by a detailed history, physical examination and various investigations. 1. CBC 2. Chest X-Ray 3. Echo Cardiography. Results: Majority of the cases in our study were of Acyanotic CHD (73%) and most of them presented during 0-1 Year of life (78.08%). Dyspnoea was the commonest symptoms seen in (62%) followed by FTT in (40%) cases and Recurrent RTI in (36%) cases, Refusal to feed in (34%) cases, cyanosis in (25%) cases, Anoxic Spell in (5%) of cases. 73 Patients had abnormal chest X-ray finding on presentation. Conclusion: Acyanotic CHD were most commonly seen in children rather than cyanotic CHD.VSD was most common acyanotic congenital heart disease in infancy. Among cyanotic CHDs, Tetralogy of Fallot is the most common lesion. All cases of CHD should be under regular monitoring so as to permit optimal growth and development. A high index of suspicion, a detailed history, physical examination, chest X-ray along with the use of 2-D-Echocardiography which not only helps us to diagnose most of the cases of congenital heart disease but also help in diagnosing severity of the lesion.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"12 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75920324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of plasma total cholesterol-VLDL cholesterol ratio (TC/VLDLC) in Type-2 diabetes mellitus","authors":"S. Srinivas, S. Nagendra, Prashanthkumar Goudappala, T. KashinathR","doi":"10.7439/IJBR.V9I1.4577","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4577","url":null,"abstract":"Dyslipidemia is a significant predisposing factor of diabetes mellitus induced cardio vascular complications in Type-2 Diabetes mellitus (T2DM) subjects. Triacylglycerols and Cholesterol along with phospholipids forms the basic components of tissue lipids and alterations either in their formation or in their composition leads to dyslipidemia. VLDL transports most of the endogenous triacylglyerols. This study was undertaken to assess the significance of plasma total cholesterol- VLDLC ratio (TC/VLDLC) in assessing dyslipidemic status of T2DM subjects as well as to compare the utility of this ratio with known cardio vascular disease markers like Atherogenic Coefficient and Atherogenic Index of Plasma. T-2DM subjects in the age group of 35-65 years attending Medicine OPD, Subbaiah Medical College Hospital and Research center, Shivamogga for routine check-up were randomly selected. A fasting heparinised blood sample was collected from normal control subjects as well as T-2DM subjects. The samples were centrifuged, separated plasma employed for estimation of Total Cholesterol, Triacylglycerol, HDL-Cholesterol and fasting glucose levels. VLDL Cholesterol, Atherogenic Coefficient (AC), Atherogenic Index of Plasma (AIP) and TC/VLDLC ratio calculated. A significant raise(p<0.001) is observed in levels of fasting glucose, TC,TAG, VLDLC, AC, and AIP in T2DM subjects as compared to normal control subjects where as a significant fall is seen in the calculated values of TC/VLDLC ratio. Hence it can be concluded that along with AC and AIP the TC/VLDLC ratio is a valuable additional marker of diabetes induced dyslipidemia suggesting its clinical utility in assessing and prevention of dyslipidemia induced cardio vascular complications in T2DM subjects.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"2 1","pages":"36-39"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79964239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of gender on nerve conduction velocity in healthy adults in urban population of a developing country","authors":"Wasim Rahaman, M. Ghosh, A. Chaudhuri, S. Majumdar, M. Ghar, A. Biswas","doi":"10.7439/IJBR.V9I1.4541","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4541","url":null,"abstract":"Background: Gender plays important role on amplitude, duration and latency of motor and sensory nerve conduction studies. Aims: To compare the effect of gender on nerve conduction properties of upper and lower limbs in Median and Tibial nerves in an urban population of eastern India. Materials and methods: 60 healthy adults (30 male and 30 female volunteers) in the age group of 18 to 60 years without any significant present or past systemic illness were selected for the study. Nerve Conduction Study of both Right and Left Median nerve in case of Upper Limbs and both Right and Left Tibial nerve in case of Lower Limb were performed. Results were analysed using SPSS version 16. Results: In right median nerve Proximal and Distal Latency were more in males; Proximal and Distal Amplitude were more in females; Nerve Conduction Velocity was more in males; F-Wave Latency was more in males.In left median nerve Proximal and Distal Latency were more in male; Proximal and Distal Amplitude were more in females; Nerve Conduction Velocity was more in males; F-Wave Latency was more in males. In right Tibial nerve Distal Latency was more in males; Proximal and Distal Amplitude were more in females; Nerve Conduction Velocity was more in males; F-Wave Latency was more in females.In left tibial nerve Distal Latency was significantly more in males; Proximal and Distal Amplitude were more in females; Nerve Conduction Velocity was more in males; F-Wave Latency was significantly more in females. Conclusions: The Nerve Conduction Study Parametersvaries according to gender. This variation is due to difference in Height, Limb Length, Weight, BMI, Thickness and Density of subcutaneous tissue, Muscle Mass. Influence of gender must be taken into consideration during Nerve Conduction Study and establishing normative data for reference value of Neurophysiological Laboratories for different population remains essential.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"24 1","pages":"12-17"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80101424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of neurodevelopmental abnormalities in children with severe acute malnutrition between the age of 6 months to 30 months","authors":"V. Jain, Swati Patel, N. Agarwal, A. Gaur","doi":"10.7439/IJBR.V9I1.4547","DOIUrl":"https://doi.org/10.7439/IJBR.V9I1.4547","url":null,"abstract":"Objectives : To assess the developmental abnormalities in Severe Acute Malnutrition using Developmental Assessment Scale for Indian Infants (DASII). Design: Hospital based Prospective Analytical Study. Setting : Department of Pediatrics, Kamla Raja Hospital, Gajra Raja Medical College, Gwalior. Participants: Children with severe acute malnutrition as per criteria of WHO between the age of 6 months and 30 months admitted in the hospital between March 2015 to January 2017. Method: Patients were first managed as per WHO guidelines of SAM. At the end of stabilization phase detailed neurological examination was done to look for neurological deficits by Development Assessment Scale for Indian Infants (DASII). Results: A total of 70 cases were enrolled. Mean Development Quotient for cases was 79.7(23.5) against a population mean of 112.28(10.7) (p 11.5cm [91.5(16.4)]. On analyzing patients having stunting, it was found that a significant proportion of them had low Motor DQ (chi 2 4.1, p value 0.023), low Mental DQ (chi 2 2.9, p value 0.038), and low Mean DQ (chi 2 3.1, p value 0.036) when compared to patients not having stunting. Conclusions : SAM patients have both low Mental DQ and Motor DQ. Low MUAC is associated with Low Motor DQ. Stunting is associated with low Motor and Mental DQ.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"54 1","pages":"18-20"},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83128227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}