Jonathan Osei-Owusu, Kwabena Boakye Kokro, Andrew Ofori, Joseph Apau, Aboagye Kwarteng Dofuor, Bright Yaw Vigbedor, Albert Aniagyei, Ralph Kwakye, George Edusei, Boniface Yeboah Antwi, Harry Okyere
{"title":"Evaluation of phytochemical, proximate, antioxidant, and anti-nutrient properties of <i>Corchorus olitorius, Solanum macrocarpon</i> and <i>Amaranthus cruentus</i> in Ghana.","authors":"Jonathan Osei-Owusu, Kwabena Boakye Kokro, Andrew Ofori, Joseph Apau, Aboagye Kwarteng Dofuor, Bright Yaw Vigbedor, Albert Aniagyei, Ralph Kwakye, George Edusei, Boniface Yeboah Antwi, Harry Okyere","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>In Ghana, <i>Corchorus olitorius, Solanum macrocarpon</i> and <i>Amaranthus cruentus</i> are green leafy vegetables that are customarily eaten together with a starchy staple food. The present study aimed at assessing the ethanolic leaf extract of <i>C. olitorius</i>, <i>S. macrocarpon</i> and <i>A. cruentus</i> for antioxidant capacity, phytochemical property, nutritional and anti-nutrient content.</p><p><strong>Method: </strong>Phytochemical constituent and proximate analysis were determined using standard protocols. The DPPH scavenging activity was used to determine the antioxidant activity of the ethanolic leaf extracts from the three vegetables. The antinutrients phytate and oxalate were determined by titrimetric methods of analysis.</p><p><strong>Results: </strong>Pytochemical screening revealed the presence of tannins and flavonoids in <i>C. olitorius</i>, <i>S. macrocarpon</i> and <i>A. cruentus</i>. Alkaloids and saponins were present in <i>C. olitorius</i> and <i>S. macrocarpon</i> but not in <i>A. cruentus</i>. Terpenoids, steroids, carotenoids and coumarins were absent in all the three vegetables. Proximate analysis revealed varying levels of moisture, fat, protein, ash, crude fibre and carbohydrates in the three leafy vegetables. The DPPH scavenging showed 86.71%, 71.72% and 38.86% activity for <i>S. macrocarpon</i>, <i>C. olitorius</i> and <i>A. cruentus</i> respectively. The antinutrient results revealed an oxalate level of 2.7 ± 0.13% for <i>C. olitorius</i>, 6.43 ± 0.06% for <i>A. cruentus</i> and 12.32 ± 0.13% for <i>S. macrocarpon</i>. For levels of phytates, our results revealed a 3.084 ± 0.54%, 1.14 ± 0.26% and 1.71 ± 0.27% for <i>C. olitorius</i>, <i>A. cruentus</i> and <i>S. macrocarpon</i>, respectively.</p><p><strong>Conclusion: </strong>The current study has shown that <i>C. olitorius</i>, <i>A. cruentus</i> and <i>S. macrocarpon</i> possess important phytochemicals, nutrients and significant antioxidant activity, suggesting a potential of these vegetables against diverse disease, if eaten by humans.</p>","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"14 2","pages":"17-24"},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195395/pdf/ijbmb0014-0017.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9504227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel therapeutic strategies for the treatment of chronic hepatitis-B viral infection","authors":"A. Kar, Deoraj Sharma","doi":"10.33545/26646501.2023.v5.i2a.48","DOIUrl":"https://doi.org/10.33545/26646501.2023.v5.i2a.48","url":null,"abstract":"","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76012041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Mid-regional pro-adrenomedullin (MR-proADM) and same biochemical parameters in diabetes mellitus type 2 patients","authors":"N. Aziz","doi":"10.33545/26646501.2023.v5.i2a.44","DOIUrl":"https://doi.org/10.33545/26646501.2023.v5.i2a.44","url":null,"abstract":"","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"2013 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82609361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dina El Bery, S. El-Masry, A. Guirgis, Dr. Hany Khalil
{"title":"DNA methylation progress is involved in influenza a virus infection","authors":"Dina El Bery, S. El-Masry, A. Guirgis, Dr. Hany Khalil","doi":"10.33545/26646501.2023.v5.i2a.45","DOIUrl":"https://doi.org/10.33545/26646501.2023.v5.i2a.45","url":null,"abstract":"","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91004601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiotherapy effective clonogens model graphical optimization approaching linear quadratic method for head and neck tumors","authors":"F. Casesnoves","doi":"10.33545/26646501.2023.v5.i1a.37","DOIUrl":"https://doi.org/10.33545/26646501.2023.v5.i1a.37","url":null,"abstract":"","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89427346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riddhi Shah, Regiane Cristina do Nascimento Miranda, Daniel Alves dos Santos, Edvande Xavier dos Santos Filho
{"title":"Water quality from Ribeirão Santana downstream the rural area of São Luís de Montes Belos, Goiás, Brazil","authors":"Riddhi Shah, Regiane Cristina do Nascimento Miranda, Daniel Alves dos Santos, Edvande Xavier dos Santos Filho","doi":"10.33545/26646501.2023.v5.i2a.49","DOIUrl":"https://doi.org/10.33545/26646501.2023.v5.i2a.49","url":null,"abstract":"Industrial waste thrown into waterways is a major problem in Brazil. On that premise, this work evaluated the water quality from Ribeirão Santana downstream the area of São Luís de Montes Belos, Goiás, Brazil throughout the year 2021. Physical-chemical and microbiological evaluation revealed inconsistencies (p","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135652624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Darakhshandeh, Elham Fathi, Ali Haji Gholami, Farzaneh Ashrafi, Valiollah Mehrzad, Elahe Nasri
{"title":"Bacterial spectrum and antimicrobial resistance pattern in cancer patients with febrile neutropenia.","authors":"Ali Darakhshandeh, Elham Fathi, Ali Haji Gholami, Farzaneh Ashrafi, Valiollah Mehrzad, Elahe Nasri","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Bloodstream infections are serious complications in neutropenic cancer patients. There has been a universal pickup in multidrug resistant (MDR) strains. For individuals who are at high risk for infections caused by MDR bacteria, a novel de-escalation strategy has been developed. Determine the bacterial spectrum and antibiotic resistance pattern in febrile neutropenic cancer patients was the goal of this investigation.</p><p><strong>Materials and methods: </strong>From 2019 to 2020, 60 cancer patients with febrile neutropenia who were sent to Isfahan's Omid Hospital were included in this retrospective analysis. Experiments were done on the antimicrobial susceptibility of isolated bacterial infections.</p><p><strong>Results: </strong>The patients' average age was 43.35±15.59 years. Ninety-one percent (55/61) of the 60 patients had hematologic malignancies, and 8.3 percent (5/61) had solid tumors. The majority of the germs were gram-negative bacteria (66.7 percent). E. coli was the pathogen that was isolated the most frequently (26.7%), followed by Klebsiella (16.7 percent). In addition, the most prevalent identified Gram-positive bacteria was Staphylococcus epidermidis (21.7 percent). Third-generation cephalosporin (ESBL-E) resistance was present in 50% of E. coli, along with 50% resistance to cotrimoxazole, ciprofloxacin, and piperacillin, 31% resistance to amikacin, and 20% resistance to meropenem (CRE). They had an 80% sensitivity to amikacin and a 70% sensitivity to ciprofloxacin. Ten percent of our patients had antibiotic resistance in the antibiogram (XDR).</p><p><strong>Conclusion: </strong>In summary, most bacterial infections were resistant to different medications. The emergence and spread of Gram-negative bacteria that are resistant to antibiotics can be stopped by prudent antibiotic use.</p>","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"14 1","pages":"10-16"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018003/pdf/ijbmb0014-0010.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9514479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Environmental and immunonutrition effects on public health linked to water pollutants and fish disease","authors":"D. Tadese","doi":"10.33545/26646501.2023.v5.i1a.36","DOIUrl":"https://doi.org/10.33545/26646501.2023.v5.i1a.36","url":null,"abstract":"","PeriodicalId":13891,"journal":{"name":"International journal of biochemistry and molecular biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87795764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}