International Journal of Analytical Chemistry最新文献_第9页

Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods. 使用不同的分析方法评估牛奶和肉类中的抗生素残留。

IF 1.5 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-06-30 eCollection Date: 2023-01-01 DOI: 10.1155/2023/4380261

Melaku Getahun, Rahel Belete Abebe, Ashenafi Kibret Sendekie, Alem Endeshaw Woldeyohanis, Asmamaw Emagn Kasahun

{"title":"Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods.","authors":"Melaku Getahun, Rahel Belete Abebe, Ashenafi Kibret Sendekie, Alem Endeshaw Woldeyohanis, Asmamaw Emagn Kasahun","doi":"10.1155/2023/4380261","DOIUrl":"10.1155/2023/4380261","url":null,"abstract":"Veterinary drugs are pharmacologically and biologically active chemical agents. At present, veterinary drugs are extensively used to prevent and treat animal diseases, to promote animal growth, and to improve the conversion rate of feed. However, the use of veterinary drugs in food-producing animals may leave residues of the parent compounds and/or their metabolites in food products resulting in harmful effects on humans. To ensure food safety, sensitive and effective analytical methods have been developing rapidly. This review describes sample extraction and cleanup methods, and different analytical techniques are used for the determination of veterinary drug residues in milk and meat. Sample extraction methods, such as solvent extraction, liquid-liquid extraction, and cleanup methods such as dispersive solid-phase extraction and immunoaffinity chromatography, were summarized. Different types of analytical methods such as microbial, immunological, biosensor, thin layer chromatography, high-performance liquid chromatography, and liquid chromatography-tandem mass spectrometry were discussed for the analysis of veterinary drug residues in animal-derived foods. Liquid chromatography-tandem mass spectrometry is the most widely used analytical technique for the determination of antibiotic drug residues. This is due to the powerful separation of LC and accurate identification of MS, and LC-MS/MS is more popular in the analysis of veterinary drug residues.","PeriodicalId":13888,"journal":{"name":"International Journal of Analytical Chemistry","volume":"2023 ","pages":"4380261"},"PeriodicalIF":1.5,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9809577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioassay and RP-HPLC Method Development for the Analysis of Extracts and Herbal Products Containing Anthocleista nobilis 用生物测定法和反相高效液相色谱法分析花青菜提取物和草药制品

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-05-30 DOI: 10.1155/2023/6957519

Rahinatu Ali Bawa, John Nii Addotey, Abena Amponsaa Brobbey, James Oppong-Kyekyeku, Christopher Kodjo Hlordzi

{"title":"Bioassay and RP-HPLC Method Development for the Analysis of Extracts and Herbal Products Containing Anthocleista nobilis","authors":"Rahinatu Ali Bawa, John Nii Addotey, Abena Amponsaa Brobbey, James Oppong-Kyekyeku, Christopher Kodjo Hlordzi","doi":"10.1155/2023/6957519","DOIUrl":"https://doi.org/10.1155/2023/6957519","url":null,"abstract":"Anthocleista nobilis is a common constituent in numerous conventional medications in West Africa. The stem bark of A. nobilis is known to contain brucine and is used to treat intestinal parasites, stomachaches, gonorrhoea, wounds, etc. The extensive use has led to high market value and adulteration of their herbal products. In this work, the antioxidant properties of extracts of A. nobilis are verified, and a validated RP-HPLC method is used to estimate the brucine content of extracts and products containing A. nobilis. Stem bark extracts from ethyl acetate, 96% v/v ethanol, 70% v/v ethanol, and water of A. nobilis were investigated for phytochemical content using standard methods and their antioxidant activity using DPPH and phosphomolybdenum assays. An RP-HPLC method was developed and validated using brucine as a reference standard. The optimized conditions of the developed RP-HPLC method include a Supelcosil C18 column with dimensions 150 × 4.6 mm and particle size of 3 μm, a mobile phase comprising of MeOH : 0.1% v/v HCOOH (65:35 %v/v ) which was injected at a flow rate of 0.8 mL/min, and an injection volume of 50 μL. The wavelength of detection was 274 nm. The developed method was validated as per ICH guidelines. The common phytochemicals among the various extracts were tannins and alkaloids. All extracts exhibited a reasonable antioxidant activity in the DPPH and phosphomolybdenum assays, with the ethanol extract recording the highest activity of 27.681 μg/mL and 696.7452 μg/g AAE, respectively. The content of brucine in the extracts was determined to be 0.0177–0.1259 × 10–3% w/v, whereas the herbal products tested had a content of 0.8950−2.5013 × 10–3% w/v. These levels were below the toxicity threshold of brucine. The developed method could be used for the routine quality control of A. nobilis extracts and formulations.","PeriodicalId":13888,"journal":{"name":"International Journal of Analytical Chemistry","volume":"15 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138534417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analytical Validation of Smartphone Spectroscopic Technic Used in an Educational Kinetic Study 智能手机光谱技术在教育动力学研究中的应用分析验证

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-04-20 DOI: 10.1155/2023/3729633

S. Raissi, F. Fakhfakh

{"title":"Analytical Validation of Smartphone Spectroscopic Technic Used in an Educational Kinetic Study","authors":"S. Raissi, F. Fakhfakh","doi":"10.1155/2023/3729633","DOIUrl":"https://doi.org/10.1155/2023/3729633","url":null,"abstract":"Use of smartphone-based spectroscopy is showing a constant growth since last year. It presents the advantage of being widely available for everyone. The most important thing is that it is still a low-cost method adapted to the education context. However, as all analytical methods, it should be validated to ensure the reliability of its results. In this study, we present the steps of the validation process with its statistical tests applied to the dosage of di-iode. Shapiro–Wilk test revealed that our method has a random character. Homogeneity of variance analyses using the Cochran test confirmed the precision of the method. The Fisher test revealed the linearity of the model of correlation between I2 concentration and the response. The relation between response and concentration is A = 1000 C + 0.002. From the parameters of the linear regression of the model, we deduced the limits of quantification and XLq = 4·10−5 mol·L−1 and XLd = 1·10−5 mol·L−1. Thanks to tightness of the sample, the method of I2 dosage was successfully applied in iodine quantification to monitor acetone iodination during time in the context of kinetic studies with minimum system trouble. Being low cost, this method can facilitate access to physical methods in educational laboratories.","PeriodicalId":13888,"journal":{"name":"International Journal of Analytical Chemistry","volume":"1 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41553770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Carbon Nanofiber-Modified Concrete in Industrial Building Design. 纳米碳纤维改性混凝土在工业建筑设计中的应用。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-25 eCollection Date: 2023-01-01 DOI: 10.1155/2023/2587551

Tianjie Liu

{"title":"Application of Carbon Nanofiber-Modified Concrete in Industrial Building Design.","authors":"Tianjie Liu","doi":"10.1155/2023/2587551","DOIUrl":"10.1155/2023/2587551","url":null,"abstract":"In order to explore the influence law and action mechanism of carbon nanofibers on the basic mechanical properties of concrete, the author proposes the mechanical properties and microscopic mechanism of carbon nanofiber-modified concrete. Concrete was prepared with different dosages of carbon nanofibers, and the compressive strength, flexural strength, and splitting strength of carbon nanofiber-modified concrete were tested, and the modification mechanism was explored. Experimental results show that an appropriate amount of carbon nanofibers can improve the mechanical properties of concrete. When the dosage is 0.3%, the mechanical properties of carbon nanofiber-modified concrete are the best, and its compressive strength, flexural strength, and split tensile strength are increased by 9.2%, 13.2%, and 17.5%, respectively, compared with plain concrete. Carbon nanofibers can form a three-dimensional network structure inside the concrete, which can improve the microscopic morphology of the concrete, enhance the toughness and integrity of the concrete, fill the pore defects inside the concrete, refine the pore size distribution, and consume part of the fracture failure energy when the concrete is damaged.","PeriodicalId":13888,"journal":{"name":"International Journal of Analytical Chemistry","volume":"2023 ","pages":"2587551"},"PeriodicalIF":1.8,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10652081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Transcription Factor E2F1 Regulates the Expression of ADRB2. 转录因子E2F1调控ADRB2的表达。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI: 10.1155/2023/8210685

Juan Du, Feifei Rui, Zhongfen Hao, Yun Hang, Jin Shu

{"title":"Transcription Factor E2F1 Regulates the Expression of ADRB2.","authors":"Juan Du, Feifei Rui, Zhongfen Hao, Yun Hang, Jin Shu","doi":"10.1155/2023/8210685","DOIUrl":"https://doi.org/10.1155/2023/8210685","url":null,"abstract":"Adrenergic beta-2-receptor (ADRB2) is highly expressed in various tissue cells, affecting the susceptibility, development, and drug efficacy of diseases such as bronchial asthma and malignant tumor. However, the transcriptional regulatory mechanism of the human ADRB2 gene remains unclear. This study aimed to clarify whether E2F transcription factor 1 (E2F1) was involved in the transcriptional regulation of the human ADRB2 gene. First, the 5' flanking region of the human ADRB2 gene was cloned, and its activity was detected using A549 and BEAS-2B cells. Second, it was found that the overexpression of E2F1 could increase promoter activity by a dual-luciferase reporter gene assay. In contrast, treatment of knockdown of E2F1 significantly resulted in a decrease in its promoter activity. Moreover, mutation of the binding site of E2F1 greatly reduced the potential of human ADRB2 promoter transcriptional activity to be regulated by E2F1 overexpression and knockdown. Additionally, by real-time quantitative PCR and Western blot analysis, we demonstrated that overexpression of E2F1 elevated the ADRB2 mRNA expression and protein levels while si-E2F1 reduced its expression. Finally, the consequence of the chromatin immunoprecipitation assay showed that E2F1 was able to bind to the promoter region of ADRB2 in vivo. These results confirmed that E2F1 upregulated the expression of the human ADRB2 gene.","PeriodicalId":13888,"journal":{"name":"International Journal of Analytical Chemistry","volume":"2023 ","pages":"8210685"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9398971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retracted: Residential Environment Pollution Monitoring System Based on Cloud Computing and Internet of Things. 撤稿:基于云计算和物联网的居住环境污染监测系统。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI: 10.1155/2023/9858523

International Journal Of Analytical Chemistry

引用次数: 0

Simultaneous Determination and Stability Analysis of Ten New Psychoactive Substances including Synthetic Cathinones, Phenethylamines, and Ketamine Substitutes in Urine Using Liquid Chromatography-Tandem Mass Spectrometry. 液相色谱-串联质谱法同时测定尿液中合成卡西酮、苯乙胺和氯胺酮代用品等10种新型精神活性物质及其稳定性分析。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI: 10.1155/2023/9895595

Feng-Shuo Yang, Hei-Hwa Lee, Li-Ping Tseng, Yung-Hung Lee, Yung-Sheng Lan, Yi-Cheng Lee, Yi-Cheng Chou, Yi-Ching Lin

{"title":"Simultaneous Determination and Stability Analysis of Ten New Psychoactive Substances including Synthetic Cathinones, Phenethylamines, and Ketamine Substitutes in Urine Using Liquid Chromatography-Tandem Mass Spectrometry.","authors":"Feng-Shuo Yang, Hei-Hwa Lee, Li-Ping Tseng, Yung-Hung Lee, Yung-Sheng Lan, Yi-Cheng Lee, Yi-Cheng Chou, Yi-Ching Lin","doi":"10.1155/2023/9895595","DOIUrl":"https://doi.org/10.1155/2023/9895595","url":null,"abstract":"Knowing the stability of drugs is important to ensure accurate and reliable results of drug concentrations. This study evaluated the stability of ten new psychoactive substances (NPSs) in urine and methanol/water at different storage temperatures. Quantitative analyses were performed using liquid chromatography-tandem mass spectrometry. Three replicates of each storage condition were analyzed at day 0 and after 7, 14-, 30-, 60-, and 90 days with storage at +25°C, +4°C, and -20°C. For each analyte, the percent difference at each time interval from day 0 was calculated for each storage condition. Para-methoxyamphetamine (PMA), para-methoxymethamphetamine (PMMA), deschloroketamine (DCK), and 2-fluorodeschloroketamine (2-FDCK) were stable in urine, even when stored for 90-day periods at various temperatures. For synthetic cathinones, the concentrations declined over time at room temperature (+25°C) in urine but were relatively stable in methanol solvent with 0.1% formic acid. The significant degradation was found at +25°C, and the most excellent stability was shown by samples stored at -20°C. Phenethylamines (PMA and PMMA) and ketamine substitutes (DCK and 2-FDCK) were relatively more stable than synthetic cathinones (mephedrone, butylone, pentylone, ephylone, 4-MEAPP, and eutylone).","PeriodicalId":13888,"journal":{"name":"International Journal of Analytical Chemistry","volume":"2023 ","pages":"9895595"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9878118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retracted: Effect of Free Formaldehyde on Chemical Structure and Thermal Properties of Nano-Titanium Dioxide Resin. 游离甲醛对纳米二氧化钛树脂化学结构和热性能的影响。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI: 10.1155/2023/9813219

International Journal Of Analytical Chemistry

引用次数: 0

Retracted: Stability Analysis and Construction Parameter Optimization of Tunnels in the Fractured Zone of Faults. 缩回:断层破碎带隧道稳定性分析及施工参数优化。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI: 10.1155/2023/9841604

International Journal Of Analytical Chemistry

引用次数: 1

Retracted: Load Test Analysis of a Long-Span Prestressed Nano-Concrete Highway Bridge. 某大跨度预应力纳米混凝土公路桥梁荷载试验分析。

IF 1.8 4区化学

International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI: 10.1155/2023/9853014

International Journal Of Analytical Chemistry

引用次数: 0